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34 条记录 (耗时 0.024 秒)

    Preparation of small crystals
    13.
    发明授权
    Preparation of small crystals 有权
    制备小晶体

    公开(公告)号：US07326294B2

    公开(公告)日：2008-02-05

    申请号：US10513153

    申请日：2003-04-08

    申请人： Linda Jane McCausland ,  David Reay

    发明人： Linda Jane McCausland ,  David Reay

    IPC分类号： B01D9/00 ,  C30B1/00

    CPC分类号： F26B3/12 ,  A61K9/1688 ,  B01D1/18 ,  B01D9/0027 ,  B01D9/005 ,  B01D9/0054 ,  B01D9/0059 ,  B01D9/0081 ,  Y10S117/901

    摘要： Small crystals are made by mixing a solution of a desired substance with an anti-solvent in a fluidic vortex mixer in which the residence time is less than 1s, for example 10 ms. The liquid within the fluidic vortex mixer (12) is subjected to high intensity ultrasound from a transducer (20, 22). The solution very rapidly becomes supersaturated, and the ultrasound can induce a very large number of nuclei for crystal growth. Small crystals, for example less than 5 μm, are formed. The resulting suspension is treated so as to add or remove ingredients, and then spray dried using an atomizer tuned to create small droplets in such a way that each droplet should contain not more than one crystal. Crystal agglomeration is hence prevented.

    摘要翻译： 通过将所需物质的溶液与抗溶剂混合在流动涡旋混合器中制备小晶体，其中停留时间小于1秒，例如10ms。 流体涡流混合器（12）内的液体经受来自换能器（20,22）的高强度超声波。 溶液非常迅速地变得过饱和，并且超声可以诱导非常大量的用于晶体生长的核。 形成小晶体，例如小于5μm。 处理所得到的悬浮液以便添加或除去成分，然后使用调节的雾化器喷雾干燥以产生小液滴，使得每个液滴应该包含不超过一个晶体。 因此防止了晶体聚集。

    Valve with vortex chamber and a mechanical member to shut off flow
    14.
    发明授权
    Valve with vortex chamber and a mechanical member to shut off flow 失效
    阀门具有涡流室和机械构件以切断流量

    公开(公告)号：US07234489B2

    公开(公告)日：2007-06-26

    申请号：US10474733

    申请日：2002-04-02

    申请人： Michael Joseph Bowe ,  John William Stairmand

    发明人： Michael Joseph Bowe ,  John William Stairmand

    IPC分类号： F15C1/16

    CPC分类号： F16K1/443 ,  Y10T137/2115 ,  Y10T137/87346

    摘要： A valve assembly (10) comprises a vortex chamber (14) with an axial outlet port (20), a main inlet port (16) for a fluid to be controlled, and a substantially tangential inlet port (25); the fluid enters through an inlet chamber (13) in which is a mechanical valve (26) movable so as to obstruct fluid flow into the vortex chamber (14). A duct (24) links the inlet chamber (13) to the tangential inlet port (25) of the vortex chamber. The position of the mechanical valve (26) affects the flow of fluid through the duct (24), so the vortex chamber (14) amplifies the effect of the mechanical valve. Further movement of the valve (26) closes off flow altogether (40). The assembly may include a weir (36) in the outlet, to separate gas and liquid phases.

    摘要翻译： 阀组件（10）包括具有轴向出口（20），用于待控制流体的主入口（16）和基本切向的入口（25）的涡流室（14）。 流体通过入口室（13）进入，其中机械阀（26）可移动以阻止流体流入涡流室（14）。 管道（24）将入口室（13）连接到涡流室的切向入口（25）。 机械阀（26）的位置影响通过管道（24）的流体的流动，因此涡流室（14）放大机械阀的作用。 阀（26）的进一步运动完全关闭流（40）。 组件可以包括出口中的堰（36），以分离气相和液相。

    Valve assembly
    16.
    发明授权
    Valve assembly 失效

    公开(公告)号：US07073532B2

    公开(公告)日：2006-07-11

    申请号：US10519195

    申请日：2003-05-22

    申请人： Michael Joseph Bowe

    发明人： Michael Joseph Bowe

    IPC分类号： F16K11/06

    CPC分类号： F16K1/123 ,  F16K3/265 ,  F16K47/08 ,  Y10T137/86759

    摘要： A valve assembly (10) comprises a valve stem (14) with a bore (15) and radial apertures (17), and a sleeve (18) closed atone end and slidable over the valve stem (14) to obstruct the apertures (17). At the end of the valve stem opposite the outlet end, the valve stem (14) defines a fluidic vortex chamber (22) with both tangential inlets (28) and non-tangential peripheral inlets (26), and with an axial outlet (24) communicating with the bore (15). The sleeve (18) defines at least one radial port (32) near its closed end. The valve assembly operates in a conventional fashion except when approaching closure. Once the last of the apertures (17) in the valve stem has been closed, the only flow path is through the fluidic vortex chamber (22). Further movement of the sleeve (18) alters the distribution of the flow between the non-tangential inlets (26) and the tangential inlets (28), so adjusting the strength of the fluidic vortex and the resistance to fluid flow. The valve assembly (10) suppresses erosive and cavitational wear of the valve mechanism, and can provide a wide range of flow modulation.