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    Thermosensitive nanostructure for hyperthermia treatment
    12.
    发明授权
    Thermosensitive nanostructure for hyperthermia treatment 有权
    热敏纳米结构热疗治疗

    公开(公告)号：US08586095B2

    公开(公告)日：2013-11-19

    申请号：US11511464

    申请日：2006-08-29

    Applicant: Wen Hsiang Chang ,  Chao-Hung Kao ,  Chin-I Lin ,  Shian-Jy Wang

    Inventor： Wen Hsiang Chang ,  Chao-Hung Kao ,  Chin-I Lin ,  Shian-Jy Wang

    IPC: A61K9/16

    CPC classification number: A61K49/1857 ,  A61K9/1075 ,  A61K41/0052 ,  A61K49/1806 ,  B82Y5/00

    Abstract: A thermosensitive nanostructure for hyperthermia treatment. Magnetic nanoparticles are encapsulated in a thermosensitive polymer nanostructure having a lower critical solution temperature (LCST) of about 40-45° C. The thermosensitive polymer nanostructure may carry a drug. When the magnetic nanoparticles are heated to 40-45° C. by application of an alternating magnetic field in hyperthermia treatment, the thermosensitive polymer nanostructure collapses to release the drug, thus providing concurrent drug treatment.

    Abstract translation: 用于热疗治疗的热敏纳米结构。 磁性纳米颗粒被封装在具有约40-45℃的较低临界溶解温度（LCST）的热敏聚合物纳米结构中。热敏聚合物纳米结构可携带药物。 当通过在热疗处理中施加交变磁场将磁性纳米颗粒加热至40-45℃时，热敏聚合物纳米结构崩溃以释放药物，从而提供同时进行的药物治疗。

    Automatic closing and opening umbrella with fixed type of plural sections of middle rod in variable dynamic process and ratio
    15.
    发明授权
    Automatic closing and opening umbrella with fixed type of plural sections of middle rod in variable dynamic process and ratio 失效
    具有可变动态过程和比例的固定式多段中间杆的自动关闭和开伞

    公开(公告)号：US5823215A

    公开(公告)日：1998-10-20

    申请号：US651956

    申请日：1996-05-21

    Applicant: Lung-Chiao Chou ,  Chin-I Lin

    Inventor： Lung-Chiao Chou ,  Chin-I Lin

    IPC: A45B25/14

    CPC classification number: A45B25/22 ,  A45B25/143

    Abstract: This invention is an umbrella in automatic opening and closing manner with its rod in the middle, which has multiple sections, and it is in variable dynamic process including the umbrella's skeleton mechanism, spring, locating device, shuttle arrow, control mechanism, handle, change-over device and pulling rig. Its main novelty is that within the middle rod of the umbrella's skeleton, a contrivance to change is installed. At the ends of the pulling rope in the contrivance to make changes, they respectively reach the lower nest and shuttle arrow. The control mechanism is manipulated by the pressing of of the button to release the umbrella's skeleton in particular position for closing and folding and the reserve energy of the spring. In coordination with both pulling ropes, each section of skeleton is tracted to extend and make the upward movement of the lower next to open the umbrella. The locating device fastens the middle rod at the fixed position to resist against wind. It can release the traction force between sections of the skeleton under the firm control of of shuttle arrow. The spring between branch skeletons in the umbrella is to close the umbrella and to change the place to return to the original point.

    Abstract translation: 本发明是一种具有自动开闭方式的伞形杆，其中杆具有多个部分，具有伞的骨架机构，弹簧，定位装置，穿梭箭头，控制机构，手柄，变化等动态过程 - 装置和牵引装置。 其主要的新颖之处在于，在伞的骨架的中间杆内，安装了改变的设计。 在牵引绳的末端进行改变，他们分别到达下巢和穿梭箭头。 通过按下按钮来操纵控制机构，以将伞的骨架放置在特定的位置，用于关闭和折叠以及弹簧的储备能量。 与拉绳配合，骨架的每个部分被拉伸，使下部的向上运动打开伞。 定位装置将中间杆固定在固定位置以抵抗风。 它可以在穿梭箭头的牢固控制下释放骨架部分之间的牵引力。 雨伞中的分支骨架之间的春天是关闭伞，并改变地方返回原点。

    Hair growth agent having a platelet dry powder
    16.
    发明申请
    Hair growth agent having a platelet dry powder 审中-公开
    具有血小板干粉的头发生长剂

    公开(公告)号：US20120087903A1

    公开(公告)日：2012-04-12

    申请号：US13200650

    申请日：2011-09-28

    Applicant: Chin I Lin ,  Han-Lei Wan

    Inventor： Chin I Lin ,  Han-Lei Wan

    IPC: A61K35/14 ,  A61P17/14

    CPC classification number: A61K8/983 ,  A61K35/19 ,  A61Q7/00

    Abstract: A hair growth agent having an effective dose of a platelet dry powder and a pharmaceutically acceptable solvent and/or excipient, wherein the effective dose refers to the presence of at least 1,000 platelets in every milligram of the hair growth agent.

    Abstract translation: 具有有效剂量的血小板干粉和药学上可接受的溶剂和/或赋形剂的毛发生长剂，其中有效剂量是指每毫克毛发生长剂中存在至少1,000个血小板。

    Nuclear molecular imaging contrast agent
    18.
    发明申请
    Nuclear molecular imaging contrast agent 审中-公开
    核分子成像对比剂

    公开(公告)号：US20070154390A1

    公开(公告)日：2007-07-05

    申请号：US11449764

    申请日：2006-06-09

    Applicant: Huang Chien Liang ,  Hsin-Ell Wang ,  Chin-I Lin ,  Shian-Jy Wang

    Inventor： Huang Chien Liang ,  Hsin-Ell Wang ,  Chin-I Lin ,  Shian-Jy Wang

    IPC: A61K51/00 ,  A61K49/10 ,  C08G63/91 ,  C08G63/48

    CPC classification number: A61K51/065

    Abstract: A nuclear molecular imaging contrast agent. The nuclear imaging contrast agent comprises a polymer according to the structure of wherein, P is and 1 is not less than 1; D is a C3-30 dendritic moiety having a plurality of oxygen residue; Z is a C3-20 moiety having a plurality of functional groups, wherein the functional groups comprise carbonyl, carboxyl, amine, ester, amide, or chelate group; L is a radioisotope or analyte-specific moiety ; m is not less than two ; and at least one X is an analyte-specific moiety; the other X can be hydrogen atom.

    Abstract translation: 核分子成像造影剂。 核成像造影剂包含根据其结构的聚合物，其中P为1且不小于1; D是具有多个氧残基的C3-30树枝状部分; Z是具有多个官能团的C3-20部分，其中官能团包括羰基，羧基，胺，酯，酰胺或螯合基团; L是放射性同位素或分析物特异性部分; m不小于2; 并且至少一个X是分析物特异性部分; 另外X可以是氢原子。

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