公开(公告)号：US20250057188A1

公开(公告)日：2025-02-20

申请号：US18713952

申请日：2022-11-30

Applicant: DSM IP ASSETS B.V.

Inventor： Elodie BACOU ,  Yanhong LUO ,  Ursula MCCORMACK ,  Luis Fernando ROMERO MILLAN ,  Viviane VERLHAC ,  Maria WALSH

IPC: A23K10/16 ,  A23K20/163 ,  A23K20/174 ,  A23K20/20 ,  A23K50/30

Abstract: Disclosed embodiments concern a composition comprising mannan-derived oligosaccharides orycast cell wall product and vitamin C. vitamin E, vitamin D3, and selenium. The disclosedembodiments further concern a method of administering the above composition as a feedadditive to supplement the feed of. farm animals. particularly for sows and piglets. The disclosedmethod is for promoting the immunity of pigs.

公开(公告)号：US12227772B2

公开(公告)日：2025-02-18

申请号：US17050603

申请日：2019-05-21

Applicant: DSM IP ASSETS B.V.

Inventor： Christopher Mark Farrell ,  Lisa Ann Laprade ,  Otto Martin Lehmann ,  Joshua Trueheart

IPC: C12N9/10 ,  C12P33/00

Abstract: The present invention is related to modified sterol acyltransferase enzymes with improved activity and/or specificity towards acylation of the vitamin D3 precursor 7-dehydrocholesterol (7-DHC) to be used in biotechnological production of vitamin D3. The invention further relates to a yeast strain expressing said modified enzymes and their use in a process for production of vitamin D3 or derivatives and/or metabolites thereof.

公开(公告)号：US20250041320A1

公开(公告)日：2025-02-06

申请号：US18718648

申请日：2022-12-09

Applicant: DSM IP ASSETS B.V.

Inventor： Elkin AMAYA ,  Britt BLOKKER ,  Cristiano BORTOLUZZI ,  John GERRMIA ,  Alex KARAGIANNIS-VOULES ,  Estefania PEREZ CALVO ,  Jose-Otavio SORBARA

IPC: A61K31/702 ,  A23K20/163 ,  A23K50/75 ,  A61P3/02

Abstract: The present invention relates to use of oligosaccharide preparations to increase average body weight and/or to decrease feed conversion ratio and/or to increase average body weight gain of a bird, and to oligosaccharide preparations for use in treatment, amelioration and/or prophylaxis of a bird vaccinated against coccidiosis.

公开(公告)号：US20250041265A1

公开(公告)日：2025-02-06

申请号：US18715617

申请日：2022-11-29

Applicant: DSM IP Assets B.V.

Inventor： Elger FUNDA ,  Odile KRAINZ ,  Alexandru ZABARA

IPC: A61K31/375 ,  A61K9/50

Abstract: The present invention relates to a new delivery system for Vitamin C (also known as ascorbic acid and ascorbate) for the release large intestine. These nutritional ingredients are useful for gut and metabolic health in monogastric animals (such as swine and poultry as well as fish), especially in humans.

公开(公告)号：US20250040574A1

公开(公告)日：2025-02-06

申请号：US18691213

申请日：2022-08-29

Applicant: DSM IP Assets B.V.

Inventor： Maartje Maria FRANSE ,  Johanna Corline Margriet VINK ,  Mirna BOSNJAK

IPC: A23L2/66 ,  A23L2/56 ,  A23L2/60 ,  A23L29/238 ,  A23L33/15 ,  A23L33/21

Abstract: The present invention relates to a ready to mix composition comprising 30 to 60 wt. % pea and rapeseed protein, 5 to 25 wt. % dietary fiber, 0 to 15 wt. % creaming agent, 1 to 15 wt. % flavor and 0.1 to 5 wt. % hydrocolloid, wherein the ratio of pea and rapeseed protein is within the range of 80:20 to 20:80.

公开(公告)号：US20250032674A1

公开(公告)日：2025-01-30

申请号：US18718647

申请日：2022-12-12

Applicant: DSM IP ASSETS B.V.

Inventor： Mark Kenneth HAZZARD ,  Noel L. DAVISON ,  Mandy Maria Jozefina WIERMANS ,  Nicolaes Hubertus Maria DE BONT ,  Loes Heleen PLUYMEN

IPC: A61L27/48 ,  B32B5/02 ,  B32B27/12 ,  B32B27/40

Abstract: Disclosed herein are composite sheets and prosthetic medical devices formed therefrom. In an embodiment, a composite sheet has a thickness of 25-250 μm and comprises 10-70 mass %, based on the total mass of the composite sheet, of a knit fabric having thickness of 15-225 μm and comprising strands of 2-50 dtex, the strands comprising biocompatible polymer fibers, the strands comprising biocompatible polymer fibers, wherein the fabric comprises a thickness in a plurality of first locations, and pores in a plurality of second locations; and 30-90 mass %, based on the total mass of the composite sheet, of a polyurethane coating, wherein the polyurethane coating coats the fabric and fills the pores of the fabric such that the composite sheet is substantially impermeable to water.

公开(公告)号：US20250008982A1

公开(公告)日：2025-01-09

申请号：US18713582

申请日：2022-12-05

Applicant: DSM IP Assets B.V. ,  Zhejiang DSM Zhongken Biotechnology Co. Ltd

Inventor： Shanshan HE ,  Fei ZHANG

IPC: A23J3/22 ,  A23L13/40 ,  A23L13/60

Abstract: The present application relates to a texture improver. The texture improver comprises curdlan and rapeseed protein at a weight ratio of 1:9 to 9:1. When used in food, particularly in a meat product or a plant-based meat product, the texture improver can remarkably improve the texture and taste of the product, and meets clean food label requirements.

公开(公告)号：US20240400623A1

公开(公告)日：2024-12-05

申请号：US18809132

申请日：2024-08-19

Applicant: DSM IP ASSETS B.V.

Inventor： Johannes Gustaaf Ernst VAN LEEUWEN ,  Viktor Marius BOER ,  Priscilla ZWARTJENS ,  Jos VAN VUGT ,  René Marcel DE JONG

IPC: C07K14/39 ,  C12N9/02 ,  C12P19/56

Abstract: The disclosure provides a recombinant cell capable of producing a steviol glycoside, wherein the cell comprises a nucleic acid coding for a variant of a parent polypeptide, wherein the variant has steviol glycoside transport mediating activity, wherein the variant comprises an amino acid sequence which, when aligned with the amino acid sequence of the parent polypeptide, comprises at least one modification of the amino acid residue corresponding to any of the amino acids in the amino acid sequence of the parent polypeptide, wherein the variant has an improved ability to produce rebaudioside M and optionally other steviol glycosides extracellularly if compared with the parent polytpeptide when measured under the same conditions.

公开(公告)号：US20240397917A1

公开(公告)日：2024-12-05

申请号：US18699673

申请日：2022-10-12

Applicant: DSM IP ASSETS B.V.

Inventor： Marco CESCO ,  Carlos LOZANO ,  Claudia SILVA

IPC: A01K67/02 ,  G01N33/68 ,  G01N33/82 ,  G01N33/84

Abstract: The present invention relates to industrial animal production. In particular the present invention relates to a method of raising a group of animals, and a method of determining analytes, in egg yolk or in the blood of an animal by ex vivo analysis of blood and/or yolk samples.

公开(公告)号：US20240374624A1

公开(公告)日：2024-11-14

申请号：US18685028

申请日：2022-08-23

Applicant: DSM IP ASSETS B.V.

Inventor： Remo CAMPICHE ,  Riccardo SFRISO

IPC: A61K31/702 ,  A61P17/10

Abstract: The present invention relates to compositions comprising at least one human milkoligosaccharide selected from the group consisting of 2′-fucosyllactose, difucosyllactose and/or lacto-N-tetraose as an anti-microbial agent against Cutibacterium acnes (C. acnes) as well as the use thereof in a regimen to prevent and/or treat acne comprising the steps of topically administering a composition comprising said human milk oligosaccharide(s) to the skin of a subject with acne/acne prone skin followed by topically administering a composition comprising one or more non-pathogenic live bacterial C. acnes strains.