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公开(公告)号：US20090318436A1
公开(公告)日：2009-12-24
申请号：US12287791
申请日：2008-10-14
Applicant: Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michelle Potashman , Aaron C. Siegmund , Stephanie K. Springer , Markian Stec , Ning Xi , Kevin Yang
Inventor： Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michelle Potashman , Aaron C. Siegmund , Stephanie K. Springer , Markian Stec , Ning Xi , Kevin Yang
IPC: A61K31/5355 , C07D487/02 , A61K31/5025 , C07D413/14 , C07D471/02 , A61K31/437 , A61K31/53 , C07D498/02 , A61K31/4355 , A61P35/00
CPC classification number: C07D471/04 , C07D487/04 , C07D493/04 , C07D495/04 , C07D498/04 , C07D519/00
Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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公开(公告)号：US20090124612A1
公开(公告)日：2009-05-14
申请号：US11879034
申请日：2007-07-13
Applicant: Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michele Potashman , Aaron C. Siegmund , Stephanie Springer , Markian Stec , Ning Xi , Kevin Yang
Inventor： Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michele Potashman , Aaron C. Siegmund , Stephanie Springer , Markian Stec , Ning Xi , Kevin Yang
IPC: A61K31/5377 , C07D487/04 , C07D471/04 , A61P35/04 , A61K31/437 , A61K31/5025
CPC classification number: C07D471/04
Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Abstract translation: 所选化合物对于预防和治疗诸如HGF介导的疾病等疾病是有效的。 本发明包括新颖的化合物，类似物，前药和药学上可接受的盐，用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。
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公开(公告)号：US20090124609A1
公开(公告)日：2009-05-14
申请号：US12009123
申请日：2008-01-15
Applicant: Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michele Potashman , Aaron C. Siegmund , Stephanie Springer , Markian Stec , Ning Xi , Kevin Yang
Inventor： Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michele Potashman , Aaron C. Siegmund , Stephanie Springer , Markian Stec , Ning Xi , Kevin Yang
IPC: A61K31/538 , C07D487/02 , A61K31/5025 , C07D413/14 , A61K31/5377 , A61P35/00 , C07D471/02 , A61K31/437 , A61K31/53 , C07D265/36
CPC classification number: A61K31/538 , A61K31/437 , A61K31/497 , A61K31/5025 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K45/06 , C07D403/12 , C07D471/04 , C07D473/34 , C07D487/04 , C07D493/04 , C07D495/04 , C07D498/04 , C07D519/00
Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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公开(公告)号：US08314087B2
公开(公告)日：2012-11-20
申请号：US12070309
申请日：2008-02-15
Applicant: Brian K. Albrecht , Steven Bellon , Shon Booker , Alan C. Cheng , Derin D'Amico , Noel D'Angelo , Jean-Christophe Harmange , Tae-Seong Kim , Longbin Liu , Mark H. Norman , Aaron C. Siegmund , Markian Stec , Ning Xi , Kevin Yang
Inventor： Brian K. Albrecht , Steven Bellon , Shon Booker , Alan C. Cheng , Derin D'Amico , Noel D'Angelo , Jean-Christophe Harmange , Tae-Seong Kim , Longbin Liu , Mark H. Norman , Aaron C. Siegmund , Markian Stec , Ning Xi , Kevin Yang
IPC: C07D215/233 , C07D413/14 , C07D205/08 , C07D409/14 , C07D401/14 , C07D239/36 , A61K31/4709 , A61K31/5355 , A61K31/397 , A61K31/497 , A61K31/506 , A61P35/00
CPC classification number: C07D237/16 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/14 , C07D471/04
Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Abstract translation: 所选化合物对于预防和治疗诸如HGF介导的疾病等疾病是有效的。 本发明包括新颖的化合物，类似物，前药和药学上可接受的盐，用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。
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公开(公告)号：US20080280917A1
公开(公告)日：2008-11-13
申请号：US12070309
申请日：2008-02-15
Applicant: Brian K. Albrecht , Steven Bellon , Shon Booker , Alan C. Cheng , Derin D'Amico , Noel D'Angelo , Jean-Christophe Harmange , Tae-Seong Kim , Longbin Liu , Mark H. Norman , Aaron C. Siegmund , Markian Stec , Ning Xi , Kevin Yang
Inventor： Brian K. Albrecht , Steven Bellon , Shon Booker , Alan C. Cheng , Derin D'Amico , Noel D'Angelo , Jean-Christophe Harmange , Tae-Seong Kim , Longbin Liu , Mark H. Norman , Aaron C. Siegmund , Markian Stec , Ning Xi , Kevin Yang
IPC: A61K31/501 , C07D403/12 , A61K31/4709 , A61P25/00 , A61P35/00 , C07D471/00
CPC classification number: C07D237/16 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/14 , C07D471/04
Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Abstract translation: 所选化合物对于预防和治疗诸如HGF介导的疾病等疾病是有效的。 本发明包括新颖的化合物，类似物，前药和药学上可接受的盐，用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。
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Patent Agency Ranking
公开(公告)号：US07060834B2
公开(公告)日：2006-06-13
申请号：US10488066
申请日：2002-08-23
Applicant: Derin D'Amico
Inventor： Derin D'Amico
IPC: A61K31/47 , C07D215/38 , C07D215/46
CPC classification number: C07D417/12 , C07D215/44
Abstract: Compounds useful for the treatment of pain in accord with the following structural diagram, wherein A, R1, b, R4, R5, R6, R7 and R8 are any of a number of groups as defined in the specification, and pharmaceutical compositions and methods of treatment utilizing such compounds.
Abstract translation: 用于治疗疼痛的化合物，符合以下结构图，其中A，R 1，B，R 4，R 5， R 6，R 7和R 8是本说明书中定义的多个基团中的任何一个，并且药物组合物和治疗方法利用 这样的化合物。
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公开(公告)号：US20060100216A1
公开(公告)日：2006-05-11
申请号：US11247050
申请日：2005-10-11
Applicant: Benny Askew , Jian Chen , Derin D'Amico , Thomas Nguyen , Kevin Yang
Inventor： Benny Askew , Jian Chen , Derin D'Amico , Thomas Nguyen , Kevin Yang
IPC: A61K31/496 , A61K31/454 , A61K31/452 , C07D405/14 , C07D403/14
CPC classification number: C07C271/22 , C07C2603/18 , C07D249/04 , C07D295/135 , C07D311/68 , C07D405/04 , C07D405/06 , C07D405/14
Abstract: The invention encompasses novel compounds and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for treatment of diseases mediated by B1 bradykinin receptor.
Abstract translation: 本发明包括新颖的化合物及其药学上可接受的衍生物，用于治疗由B1缓激肽受体介导的疾病的药物组合物和方法。
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公开(公告)号：US20050234044A1
公开(公告)日：2005-10-20
申请号：US10823372
申请日：2004-04-13
Applicant: Robert Groneberg , James Zhan , Benny Askew , Derin D'Amico , Nianhe Han , Christopher Fotsch , Qingyian Liu , Babak Riahi , Jiawang Zhu , Kevin Yang , Jian Chen , Rana Nomak
Inventor： Robert Groneberg , James Zhan , Benny Askew , Derin D'Amico , Nianhe Han , Christopher Fotsch , Qingyian Liu , Babak Riahi , Jiawang Zhu , Kevin Yang , Jian Chen , Rana Nomak
IPC: A61K31/425 , A61K31/4523 , A61K31/454 , A61K31/4545 , A61K31/4709 , A61K31/517 , A61K31/55 , A61P29/00 , C07D207/48 , C07D211/96 , C07D215/58 , C07D217/22 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/02 , C07D413/14 , C07D417/02 , C07D417/12 , C07D417/14 , C07D43/02
CPC classification number: C07D207/48 , C07D211/96 , C07D215/58 , C07D217/22 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14
Abstract: Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Abstract translation: 所选化合物对于治疗疼痛和疾病如炎症介导的疾病是有效的。 本发明包括新的化合物，类似物，前药和其药学上可接受的衍生物，用于预防和治疗疾病和其它疾病或涉及疼痛，炎症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。
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公开(公告)号：US20050131020A1
公开(公告)日：2005-06-16
申请号：US10488025
申请日：2002-08-23
Applicant: Derin D'Amico
Inventor： Derin D'Amico
IPC: A61K31/4706 , A61K31/5377 , A61P25/02 , A61P25/04 , A61P29/00 , A61P43/00 , C07D215/44 , C07D215/38 , A61K31/47 , A61K31/4709 , C07D41/02
CPC classification number: A61K31/5377 , A61K31/4706 , C07D215/44
Abstract: Compounds useful for the treatment of pain in accord with the following structural diagram, wherein A, R1, b, R3, d, R4, R5, R6 and R7 are any of a number of groups as defined in the specification, and pharmaceutical compositions and methods of treatment utilizing such compounds.
Abstract translation: 用于治疗疼痛的化合物符合以下结构图，其中A，R 1，b，R 3，d，R 4， >，R 5，R 6和R 7是本说明书中定义的多个基团中的任何一个，以及药物组合物和方法 利用这些化合物进行治疗。
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公开(公告)号：US20050124654A1
公开(公告)日：2005-06-09
申请号：US10823377
申请日：2004-04-12
Applicant: Robert Groneberg , Bonny Askew , Derin D'Amico , James Zhan , Andras Toro , Youngboo Kim , David Mareska , Nianhe Han , Christopher Fotsch , Qingyian Liu , Babak Riahi , Kevin Yang , Aiwen Li , Chester Yuan , Kaustav Biswas , Scott Harried , Thomas Nguyen , Wenyuan Qian , Jian Chen , Rana Nomak
Inventor： Robert Groneberg , Bonny Askew , Derin D'Amico , James Zhan , Andras Toro , Youngboo Kim , David Mareska , Nianhe Han , Christopher Fotsch , Qingyian Liu , Babak Riahi , Kevin Yang , Aiwen Li , Chester Yuan , Kaustav Biswas , Scott Harried , Thomas Nguyen , Wenyuan Qian , Jian Chen , Rana Nomak
IPC: A61K31/18 , A61K31/277 , A61K31/405 , A61K31/47 , A61P25/04 , A61P29/00 , C07C311/19 , C07C311/29 , C07D205/04 , C07D207/12 , C07D207/16 , C07D207/20 , C07D209/14 , C07D209/16 , C07D209/40 , C07D209/52 , C07D211/38 , C07D211/44 , C07D211/46 , C07D211/60 , C07D211/70 , C07D213/42 , C07D213/56 , C07D213/64 , C07D215/38 , C07D215/40 , C07D215/42 , C07D217/22 , C07D233/54 , C07D239/74 , C07D271/08 , C07D277/64 , C07D279/02 , C07D285/14 , C07D295/125 , C07D295/13 , C07D295/135 , C07D307/14 , C07D307/28 , C07D307/79 , C07D307/81 , C07D311/68 , C07D317/58 , C07D333/20 , C07D333/24 , C07D333/58 , C07D333/62 , C07D405/04 , C07D405/06 , C07D405/12 , C07D407/06 , C07D407/12 , C07D409/06 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/08
CPC classification number: C07C311/19 , C07C311/13 , C07C311/29 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07C2602/10 , C07D205/04 , C07D207/12 , C07D207/16 , C07D207/20 , C07D209/14 , C07D209/16 , C07D209/40 , C07D209/52 , C07D211/38 , C07D211/44 , C07D211/46 , C07D211/60 , C07D211/70 , C07D213/42 , C07D213/56 , C07D213/64 , C07D215/38 , C07D215/40 , C07D215/42 , C07D217/22 , C07D233/54 , C07D239/74 , C07D271/08 , C07D277/64 , C07D279/02 , C07D285/14 , C07D295/125 , C07D295/13 , C07D295/135 , C07D307/14 , C07D307/28 , C07D307/79 , C07D307/81 , C07D311/68 , C07D317/58 , C07D333/20 , C07D333/24 , C07D333/58 , C07D333/62 , C07D405/04 , C07D405/06 , C07D405/12 , C07D407/06 , C07D407/12 , C07D409/06 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/08
Abstract: Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Abstract translation: 所选化合物对于治疗疼痛和疾病如炎症介导的疾病是有效的。 本发明包括新的化合物，类似物，前药和其药学上可接受的衍生物，用于预防和治疗疾病和其它疾病或涉及疼痛，炎症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。
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