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21 条记录 (耗时 0.019 秒)

    DEVICE FOR APPLYING ADJUNCT IN ENDOSCOPIC PROCEDURE
    13.
    发明申请
    DEVICE FOR APPLYING ADJUNCT IN ENDOSCOPIC PROCEDURE 有权
    内镜手术治疗的手段

    公开(公告)号：US20130037596A1

    公开(公告)日：2013-02-14

    申请号：US13206752

    申请日：2011-08-10

    申请人： Brian W. Bear ,  Thu Anh Le ,  Thomas W. Lytle, IV ,  Mark D. Overmyer ,  Michael Setser ,  Bret W. Smith ,  Joseph Zavatsky ,  Kreena Modi

    发明人： Brian W. Bear ,  Thu Anh Le ,  Thomas W. Lytle, IV ,  Mark D. Overmyer ,  Michael Setser ,  Bret W. Smith ,  Joseph Zavatsky ,  Kreena Modi

    IPC分类号： A61B17/068

    CPC分类号： A61B17/07207 ,  A61B17/07292 ,  A61B2017/00495 ,  A61B2017/00893 ,  A61B2017/07271 ,  A61B2017/2927

    摘要： A modular end effector delivers a therapeutic agent onto tissue that has been severed and/or stapled. The end effector is removably attached to a device. The device applies force to a piston of the end effector. The force causes a distal movement of a piston along a wall disposed within the end effector. The piston engages with agents stored on opposite sides of the wall, moving the agents distally to a mixture space. The agents are mixed in the mixture space and expelled through a tip. Staples may be embedded in or disposed below a foam block, which is disposed within a staple cartridge. Via an endoscopic stapling device, coated staples are driven through tissue while interacting with another agent on the device or the cartridge. The interaction forms a tissue restoring material that is applied onto the tissue.

    摘要翻译： 模块化的末端执行器将治疗剂递送到已被切断和/或装订的组织上。 端部执行器可拆卸地连接到装置。 该装置对末端执行器的活塞施加力。 该力导致活塞沿着设置在末端执行器内的壁的远端移动。 活塞与存储在壁的相对侧上的试剂接合，将试剂向远端移动到混合物空间。 将试剂在混合物空间中混合并通过尖端排出。 钉书钉可以嵌入或设置在布置在钉仓内的泡沫块的下方。 通过内窥镜缝合装置，当与装置或药筒上的另一药剂相互作用时，涂布的钉被驱动通过组织。 相互作用形成施加到组织上的组织恢复材料。

    Surgical staple cartridge with self-dispensing staple buttress
    16.
    发明授权
    Surgical staple cartridge with self-dispensing staple buttress 有权
    手术钉盒，具有自分散钉支撑

    公开(公告)号：US09101359B2

    公开(公告)日：2015-08-11

    申请号：US13231064

    申请日：2011-09-13

    申请人： Bret W. Smith ,  Thomas W. Lytle, IV ,  Matthew C. Miller ,  Yi-Lan Wang ,  Joseph Zavatsky ,  Kreena Modi ,  Aron O. Zingman

    发明人： Bret W. Smith ,  Thomas W. Lytle, IV ,  Matthew C. Miller ,  Yi-Lan Wang ,  Joseph Zavatsky ,  Kreena Modi ,  Aron O. Zingman

    IPC分类号： A61B17/068 ,  A61B17/072

    CPC分类号： A61B17/07292 ,  A61B2017/07214 ,  A61B2017/07271

    摘要： A surgical instrument includes a handle portion, a shaft housing a firing bar, an end effector comprising an anvil, a lower jaw, and a stapling and severing assembly responsive to a longitudinal closing motion produced by the handle portion and the shaft. The lower jaw is configured to receive a removable cartridge when in an open position. The cartridge includes a housing, a plurality of staples disposed in the housing, and a deck disposed over the plurality of staples. The deck defines apertures, with each aperture being substantially disposed over each staple. The instrument includes a movable buttress that is integral with the housing of the cartridge or integral with the lower jaw of the end effector. The buttress may attach to the anvil and include a portion to receive tissue. The receipt of tissue urges and moves the buttress proximally inwards to further encompass the tissue.

    摘要翻译： 手术器械包括手柄部分，容纳击球杆的轴，包括砧座的末端执行器，下颚和响应于由手柄部分和轴产生的纵向关闭运动的装订和切割组件。 下颚构造成在处于打开位置时接收可移除的盒。 盒包括壳体，设置在壳体中的多个钉，以及设置在多个钉上的甲板。 甲板限定孔，每个孔基本上设置在每个钉上。 该仪器包括一个可移动的支柱，该活动支撑件与盒的壳体成一体，或与末端执行器的下颚一体。 支撑件可以附接到砧座并且包括接收组织的部分。 组织的接收促使支撑向内侧移动以进一步包围组织。

    Tissue sealants from plasma derived proteins
    17.
    发明授权
    Tissue sealants from plasma derived proteins 有权
    血浆衍生蛋白的组织密封剂

    公开(公告)号：US08846849B2

    公开(公告)日：2014-09-30

    申请号：US13107375

    申请日：2011-05-13

    申请人： Binoy K. Bordoloi ,  Joseph Zavatsky ,  Chetan Anirudh Khatri ,  Olajompo Moloye-Olabisi

    发明人： Binoy K. Bordoloi ,  Joseph Zavatsky ,  Chetan Anirudh Khatri ,  Olajompo Moloye-Olabisi

    IPC分类号： C08G63/668

    CPC分类号： A61L24/106

    摘要： The present invention is directed in one embodiment to a tissue adhesive or sealant composition comprising an electrophilic group containing cross-linking compound having a linker moiety of a diglycolic acid, a water soluble core moiety and an electrophilic group that is covalently bonded to the diglycolic acid linker moiety and a nucleophilic group containing protein. In other embodiments, the present invention is directed to a delivery device or a medical device on which the composition has been applied or incorporated therein. The present invention is also directed to a method for sealing tissue using the tissue adhesive or sealant composition.

    摘要翻译： 本发明在一个实施方案中涉及一种组织粘合剂或密封剂组合物，其包含亲电子基团，该亲电子基团含有交联化合物，该交联化合物具有二甘醇酸的接头部分，水溶性核心部分和与二甘醇酸共价结合的亲电子基团 接头部分和含亲核基团的蛋白质。 在其它实施方案中，本发明涉及其上已经施用或并入其中的组合物的递送装置或医疗装置。 本发明还涉及使用组织粘合剂或密封剂组合物密封组织的方法。

    SURGICAL STAPLE CARTRIDGE WITH SELF-DISPENSING STAPLE BUTTRESS
    19.
    发明申请
    SURGICAL STAPLE CARTRIDGE WITH SELF-DISPENSING STAPLE BUTTRESS 有权
    手术包装盒与自我分配的胸带

    公开(公告)号：US20130062394A1

    公开(公告)日：2013-03-14

    申请号：US13231064

    申请日：2011-09-13

    申请人： Bret W. Smith ,  Thomas W. Lytle, IV ,  Matthew C. Miller ,  Yi-Lan Wang ,  Joseph Zavatsky ,  Kreena Modi ,  Aron O. Zingman

    发明人： Bret W. Smith ,  Thomas W. Lytle, IV ,  Matthew C. Miller ,  Yi-Lan Wang ,  Joseph Zavatsky ,  Kreena Modi ,  Aron O. Zingman

    IPC分类号： A61B17/068

    CPC分类号： A61B17/07292 ,  A61B2017/07214 ,  A61B2017/07271

    摘要： A surgical instrument includes a handle portion, a shaft housing a firing bar, an end effector comprising an anvil, a lower jaw, and a stapling and severing assembly responsive to a longitudinal closing motion produced by the handle portion and the shaft. The lower jaw is configured to receive a removable cartridge when in an open position. The cartridge includes a housing, a plurality of staples disposed in the housing, and a deck disposed over the plurality of staples. The deck defines apertures, with each aperture being substantially disposed over each staple. The instrument includes a movable buttress that is integral with the housing of the cartridge or integral with the lower jaw of the end effector. The buttress may attach to the anvil and include a portion to receive tissue. The receipt of tissue urges and moves the buttress proximally inwards to further encompass the tissue.

    摘要翻译： 手术器械包括手柄部分，容纳击球杆的轴，包括砧座的末端执行器，下颚和响应于由手柄部分和轴产生的纵向关闭运动的装订和切断组件。 下颚构造成在处于打开位置时接收可移除的盒。 盒包括壳体，设置在壳体中的多个钉，以及设置在多个钉上的甲板。 甲板限定孔，每个孔基本上设置在每个钉上。 该仪器包括一个可移动的支柱，该活动支撑件与盒的壳体成一体，或与末端执行器的下颚一体。 支撑件可以附接到砧座并且包括接收组织的部分。 组织的接收促使支撑向内侧移动以进一步包围组织。