公开(公告)号：US4038084A

公开(公告)日：1977-07-26

申请号：US669839

申请日：1976-03-24

申请人： Tsunetomo Nakano ,  Kazuaki Nishio ,  Toshikazu Hayashi ,  Hiroshi Andou

发明人： Tsunetomo Nakano ,  Kazuaki Nishio ,  Toshikazu Hayashi ,  Hiroshi Andou

IPC分类号： C08F8/00 ,  C08C19/36 ,  C08F2/48 ,  C08F8/14 ,  C08F8/46 ,  C08F20/00 ,  C08F20/26 ,  C08F279/02 ,  C08F290/00 ,  C08F299/00 ,  G03F7/027

CPC分类号： G03F7/027 ,  C08C19/36 ,  C08F279/02 ,  Y10S430/111 ,  Y10S430/114 ,  Y10S430/115

摘要： A photo-setting composition essentially consisting of:(A) 100 weight parts of a product prepared by esterifying a maleic anhydride adduct of a liquid polybutadiene with a hydroxyl compound;(B) 10 - 150 weight parts of one or more than one kind of unsaturated compound selected from the group consisting of a hydroxyl compound identified above, a di(meth)acrylate compound and a glycidyl monoester compound; and(C) 0.5 - 10 weight parts of a benzoinether compound.

公开(公告)号：US08470549B2

公开(公告)日：2013-06-25

申请号：US13536202

申请日：2012-06-28

申请人： Kazuaki Nishio ,  Nozomu Matsukawa ,  Shigeo Yoshii

发明人： Kazuaki Nishio ,  Nozomu Matsukawa ,  Shigeo Yoshii

IPC分类号： G01N21/78 ,  G01N33/53 ,  G01N33/52

CPC分类号： G01N33/542 ,  C12Q1/26 ,  G01N33/54373 ,  G01N2333/90287

摘要： The present invention relates to a method for detecting an antigen with use of an antibody and an enzyme. Specifically, the present invention provides a method for detecting an antigen without use of a labeled-antibody. the method comprises immersing particles in a first buffer solution which is predicted to contain the antigen; wherein an antibody and a multi-copper oxidase CueO are immobilized on each surface of the particles, and the antibody reacts specifically with the antigen. The method further comprises the following steps recovering the obtained particles; mixing the particles recovered, an oxidation-reduction indicator (reductant), and a second buffer solution so as to prepare a reaction solution; measuring an activity degree of the multi-copper oxidase CueO contained in the reaction solution; determining that the first buffer solution contains the antigen based on the above activity degree.

摘要翻译： 本发明涉及使用抗体和酶检测抗原的方法。 具体而言，本发明提供了不使用标记抗体来检测抗原的方法。 该方法包括将颗粒浸入预测含有抗原的第一缓冲溶液中; 其中抗体和多铜氧化酶CueO固定在颗粒的每个表面上，并且抗体与抗原特异性反应。 该方法还包括以下步骤：回收所获得的颗粒; 混合回收的颗粒，氧化还原指示剂（还原剂）和第二缓冲溶液以制备反应溶液; 测定反应溶液中所含的多铜氧化酶CueO的活度; 基于上述活性度确定第一缓冲溶液含有抗原。

公开(公告)号：US4673773A

公开(公告)日：1987-06-16

申请号：US705745

申请日：1985-02-26

申请人： Tsunetomo Nakano ,  Hiroshi Yasuno ,  Kazuaki Nishio

发明人： Tsunetomo Nakano ,  Hiroshi Yasuno ,  Kazuaki Nishio

IPC分类号： C08G69/32 ,  C08G69/00 ,  C08G69/26 ,  C08G69/48 ,  G03F7/038 ,  H05K1/00 ,  H05K3/00 ,  H05K3/18 ,  H05K3/46 ,  H05K1/14

CPC分类号： G03F7/0387 ,  C08G69/265 ,  H05K3/4676 ,  H05K2201/09563 ,  H05K3/0023 ,  H05K3/181

摘要： In a multilayer printed circuit board comprising an insulating substrate and a plurality of circuit elements provided thereon in layers, each of which is composed of a circuit pattern and an insulating resin layer provided over the circuit pattern, the circuit patterns arranged adjacently to each other being portionwise connected electrically through via at least one hole, the improvement in which said insulating resin layer comprises a photoset resin of an aromatic polyamide having at least 10 molar % of a constitutional unit of the formula (Ia): ##STR1## wherein each of R.sup.1 and R.sup.2 independently is a hydrogen atom or a residue of a reactive organic compound, Ar.sup.1 is a divalent aromatic residue, and Ar.sup.2 is a divalent aromatic residue possessing a photosensitive group.

摘要翻译： 在包括绝缘基板和设置在其上的多个电路元件的多层印刷电路板中，每个电路板由设置在电路图案上的电路图案和绝缘树脂层构成，彼此相邻布置的电路图案是 其中所述绝缘树脂层包括具有至少10摩尔％的式（Ia）的结构单元的芳族聚酰胺的光固化树脂：其中， R 1和R 2各自独立地为氢原子或反应性有机化合物的残基，Ar 1为二价芳香族残基，Ar 2为具有感光性基团的2价芳香族残基。

公开(公告)号：US4368300A

公开(公告)日：1983-01-11

申请号：US326841

申请日：1981-12-03

申请人： Tsunetomo Nakano ,  Kazuaki Nishio ,  Hiroshi Watanabe ,  Hiroshi Yasuno

发明人： Tsunetomo Nakano ,  Kazuaki Nishio ,  Hiroshi Watanabe ,  Hiroshi Yasuno

IPC分类号： C08F2/00 ,  C08F2/50 ,  C08F2/54 ,  C08F290/00 ,  C08F299/00 ,  C08F299/02 ,  C08F299/04 ,  C08G59/00 ,  C08G59/02 ,  C08G59/17 ,  C08G59/18 ,  C08G59/40 ,  C08L63/00 ,  G03F7/033

CPC分类号： C08F299/028 ,  C08F299/0492 ,  G03F7/033 ,  Y10S525/922

摘要： A photosetting composition comprises an unsaturated acid-modified bisphenol type epoxy compound having an acryloyl radical; an oligoester diacrylate compound having a molecular weight of 420 or more; a photopolymerizable acrylate type monomeric compound having a molecular weight of 100 to 400; a bisphenol type epoxy resin having a softening point of 50.degree. C. to 150.degree. C. or a saturated acid-modified bisphenol type epoxy resin having a softening point of 50.degree. C. to 150.degree. C.; and a photopolymerization initiator, said composition having a proper viscosity and an excellent photocuring reaction rate and being able to form a photocured resinous film or article having a satisfactory Dupont impact strength, impact bending strength, and bonding property to metallic materials.

摘要翻译： 光固化组合物包含具有丙烯酰基的不饱和酸改性双酚型环氧化合物; 分子量为420以上的低聚酯二丙烯酸酯化合物; 分子量为100〜400的可光聚合的丙烯酸酯类单体化合物; 软化点为50〜150℃的双酚型环氧树脂或软化点为50〜150℃的饱和酸改性双酚型环氧树脂。 和光聚合引发剂，所述组合物具有适当的粘度和优异的光固化反应速率，并且能够形成具有令人满意的杜邦冲击强度，冲击弯曲强度和与金属材料的粘合性能的光固化树脂膜或制品。

公开(公告)号：US10563933B2

公开(公告)日：2020-02-18

申请号：US14646931

申请日：2014-01-08

申请人： Kazuaki Nishio ,  Kenji Shimoda

发明人： Kazuaki Nishio ,  Kenji Shimoda

IPC分类号： C23C4/01 ,  C23C4/06 ,  C23C4/18 ,  F28F13/18 ,  C23C4/08 ,  C23C14/16 ,  C23C14/32 ,  C23C14/58 ,  C23C4/04

摘要： A heat radiation member includes a metal base material made of a first metal material; and a plurality of heat radiation sections that are separately attached so as to disperse on a surface of the metal base material and contains a second metal material that is different from the first metal material and an oxide of the second metal material exposed on a surface of each of the respective heat radiation sections.

公开(公告)号：US20170022929A1

公开(公告)日：2017-01-26

申请号：US15117867

申请日：2015-03-18

申请人： Takashi KARITA ,  Kazunari TAKENAKA ,  Shinsuke SUGIMOTO ,  Akihiro YOSHIMURA ,  Kazuaki NISHIO

发明人： Takashi KARITA ,  Kazunari TAKENAKA ,  Shinsuke SUGIMOTO ,  Akihiro YOSHIMURA ,  Kazuaki NISHIO

IPC分类号： F02F1/16 ,  F01P3/02 ,  F02F1/36

CPC分类号： F02F1/166 ,  F01P3/02 ,  F01P2003/021 ,  F02F1/14 ,  F02F1/36

摘要： A water jacket spacer is inserted into a water jacket. The water jacket spacer includes an expansion member, a plate-shaped holder to which the expansion member is fixed, and a leaf spring that abuts the inner wall of the water jacket. The leaf spring projects from a face on the holder on the side opposite of the expansion member. The holder curves to match the shape of the water jacket. The position of the water jacket spacer in the water jacket is maintained by the biasing force of the leaf spring.

摘要翻译： 水夹套插入水套中。 水套隔套包括膨胀构件，固定有膨胀构件的板状保持器和与水套的内壁抵接的板簧。 板簧从支架的与膨胀构件相对的一侧的面突出。 支架曲线以匹配水套的形状。 水套间隔件在水套中的位置由板簧的偏置力保持。

公开(公告)号：US09295944B2

公开(公告)日：2016-03-29

申请号：US14356261

申请日：2011-12-27

申请人： Tadashi Takagaki ,  Yasuo Kinoshita ,  Kenji Shimoda ,  Kazuaki Nishio

发明人： Tadashi Takagaki ,  Yasuo Kinoshita ,  Kenji Shimoda ,  Kazuaki Nishio

IPC分类号： B01D50/00 ,  B01D53/94 ,  B01J35/04 ,  H01C17/06 ,  H01C17/28 ,  B01D53/96 ,  F01N3/20 ,  F01N3/28

CPC分类号： B01D53/94 ,  B01D53/96 ,  B01J35/04 ,  F01N3/2013 ,  F01N3/2828 ,  H01C17/06 ,  H01C17/28 ,  Y02T10/26 ,  Y10T29/49083 ,  Y10T29/49099 ,  Y10T29/49345

摘要： An electrically heated catalyst device includes a catalyst support including a ceramics, on which a catalyst is supported, a pair of surface electrodes disposed on an outer surface of the catalyst support, the surface electrodes being disposed opposite to each other and extending in an axial direction of the catalyst support, and a wiring line that externally supplies electric power to the surface electrodes, in which the catalyst support is electrically heated through the surface electrodes. A wrought member made of metal is buried in the surface electrodes, the wrought member extending in the axial direction of the catalyst support. With the configuration like this, the spreading of electric currents in the catalyst-support axis direction can be maintained even when cracks occur in the catalyst-support circumference direction in the surface electrodes.

摘要翻译： 电加热的催化剂装置包括催化剂载体，其包括在其上载有催化剂的陶瓷，设置在催化剂载体的外表面上的一对表面电极，所述表面电极彼此相对地设置并沿轴向方向 的催化剂载体的外部电力供给的电力线，以及通过表面电极对催化剂载体进行电加热的表面电极向外部供给电力的配线。 由金属制成的锻造构件埋设在表面电极中，锻造构件在催化剂载体的轴向方向上延伸。 利用这样的结构，即使在表面电极中的催化剂载体周向上发生裂纹，也能够维持催化剂载体轴方向的电流的扩散。

公开(公告)号：US20130062328A1

公开(公告)日：2013-03-14

申请号：US13577368

申请日：2011-09-14

申请人： Kenji Shimoda ,  Kazuaki Nishio ,  Yasuo Kinoshita ,  Tadashi Takagaki

发明人： Kenji Shimoda ,  Kazuaki Nishio ,  Yasuo Kinoshita ,  Tadashi Takagaki

IPC分类号： H05B3/02 ,  C23C4/12

CPC分类号： H05B3/08 ,  H05B3/42 ,  H05B2203/022 ,  H05B2203/024

摘要： An electrode according to one aspect of the present invention is formed on a base material composed of a ceramics. The electrodes includes a matrix composed of an Ni-Cr alloy (with a Cr content of 20 to 60 wt. %) or an MCrAlY alloy (M is at least one material selected from Fe, Co and Ni), and a disperse phase that is dispersed in the matrix and composed of an oxide mineral having a laminated structure. The ratio of area occupied by the disperse phase in a cross section of the electrode is 40 to 80%. With the structure like this, it is possible to suppress the increase in the electrical resistance even after a thermal cycle is performed.

摘要翻译： 根据本发明的一个方面的电极形成在由陶瓷构成的基材上。 电极包括由Ni-Cr合金（Cr含量为20〜60重量％）或MCrAlY合金（M为选自Fe，Co和Ni中的至少一种材料）构成的基体，以及分散相， 分散在基质中并由具有层压结构的氧化物矿物构成。 电极截面中分散相所占的面积比为40〜80％。 利用这样的结构，即使在进行热循环之后也可以抑制电阻的增加。

公开(公告)号：US20120309033A1

公开(公告)日：2012-12-06

申请号：US13536202

申请日：2012-06-28

申请人： Kazuaki Nishio ,  Nozomu Matsukawa ,  Shigeo Yoshii

发明人： Kazuaki Nishio ,  Nozomu Matsukawa ,  Shigeo Yoshii

IPC分类号： G01N21/78

CPC分类号： G01N33/542 ,  C12Q1/26 ,  G01N33/54373 ,  G01N2333/90287

摘要： The present invention relates to a method for detecting an antigen with use of an antibody and an enzyme. Specifically, the present invention provides a method for detecting an antigen without use of a labeled-antibody. the method comprises immersing particles in a first buffer solution which is predicted to contain the antigen; wherein an antibody and a multi-copper oxidase CueO are immobilized on each surface of the particles, and the antibody reacts specifically with the antigen. The method further comprises the following steps recovering the obtained particles; mixing the particles recovered, an oxidation-reduction indicator (reductant), and a second buffer solution so as to prepare a reaction solution; measuring an activity degree of the multi-copper oxidase CueO contained in the reaction solution; determining that the first buffer solution contains the antigen based on the above activity degree.

摘要翻译： 本发明涉及使用抗体和酶检测抗原的方法。 具体而言，本发明提供了不使用标记抗体来检测抗原的方法。 该方法包括将颗粒浸入预测含有抗原的第一缓冲溶液中; 其中抗体和多铜氧化酶CueO固定在颗粒的每个表面上，并且抗体与抗原特异性反应。 该方法还包括以下步骤：回收所获得的颗粒; 混合回收的颗粒，氧化还原指示剂（还原剂）和第二缓冲溶液以制备反应溶液; 测定反应溶液中所含的多铜氧化酶CueO的活度; 基于上述活性度确定第一缓冲溶液含有抗原。

公开(公告)号：US08309345B2

公开(公告)日：2012-11-13

申请号：US13296879

申请日：2011-11-15

申请人： Kazuaki Nishio ,  Nozomu Matsukawa ,  Shigeo Yoshii

发明人： Kazuaki Nishio ,  Nozomu Matsukawa ,  Shigeo Yoshii

IPC分类号： C12M1/34 ,  C12M3/00

CPC分类号： G01N33/54306 ,  C12Q1/26

摘要： Provided is a method for detecting an antigen without use of a labeled-antibody. A support having an antibody and a multi-copper oxidase CueO immobilized thereon is brought into contact with a first buffer solution containing the antigen, a current is measured by a potentiostat method using the support and a second buffer solution, and when the measured current is greater than or equal to 1.5×(blank value), it is determined that the antigen exists. The second buffer solution contains a substrate of the CueO and has an ionic strength falling within a range of not less than 0.3 mM and not more than 1.0 mM.

摘要翻译： 提供了不使用标记抗体来检测抗原的方法。 使具有固定在其上的抗体和多铜氧化酶CueO的载体与含有抗原的第一缓冲溶液接触，通过使用载体和第二缓冲溶液的恒电位法测量电流，并且当测量的电流为 大于或等于1.5×（空白值），则确定存在抗原。 第二缓冲溶液含有CueO的底物，离子强度在0.3mM以上1.0mM以下的范围内。