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公开(公告)号：US20090187199A1
公开(公告)日：2009-07-23
申请号：US12340588
申请日：2008-12-19
申请人： Geoffrey C. Gurtner , Gerald G. Fuller , Michael T. Longaker , Jayakumar Rajadas , Gordon Saul , C. Travis Rappleye , Evgenia Mandrusov
发明人： Geoffrey C. Gurtner , Gerald G. Fuller , Michael T. Longaker , Jayakumar Rajadas , Gordon Saul , C. Travis Rappleye , Evgenia Mandrusov
CPC分类号： A61B17/00491 , A61B17/04 , A61B17/11 , A61B17/122 , A61B17/1227 , A61B2017/1103 , A61B2017/1107
摘要： Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique.
摘要翻译： 公开了用于将非结合腔内连接在患者体内（包括血管内腔）的组合物，方法和试剂盒。 更具体地，在各个方面，本发明提供了用于连接这种非结合腔的组合物，方法和试剂盒，包括通常需要显微外科技术的小腔。
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公开(公告)号：US20090163844A1
公开(公告)日：2009-06-25
申请号：US12358159
申请日：2009-01-22
IPC分类号： A61F13/00
CPC分类号： A61F13/0243 , A61F13/00051 , A61F13/00059 , A61F13/0233 , A61F2013/00123 , A61F2013/00127 , A61F2013/00153 , A61F2013/00182 , A61F2013/0028 , A61K38/00 , A61K47/64 , A61K47/67 , B82Y5/00 , C07K5/0606 , C07K5/06113 , C07K5/0806 , C07K5/081 , C07K5/1008 , C07K7/02 , C07K9/005 , G01N33/57407 , G01N33/57419 , G01N2333/95 , G01N2500/00
摘要： Devices, bandages, kits and methods are described that can control or regulate the mechanical environment of a wound to ameliorate scar and/or keloid formation. The mechanical environment of a wound includes stress, strain, and any combination of stress and strain. The control of a wound's mechanical environment can be active, passive, dynamic, or static. The devices are configured to be removably secured to a skin surface in proximity to the wound site and shield the wound from endogenous and/or exogenous stress.
摘要翻译： 描述了可以控制或调节伤口的机械环境以改善瘢痕和/或瘢痕疙瘩形成的装置，绷带，试剂盒和方法。 伤口的机械环境包括应力，应变和应力和应变的任何组合。 创伤的机械环境的控制可以是主动的，被动的，动态的或静态的。 这些装置被构造成可移除地固定到靠近伤口部位的皮肤表面，并且将伤口屏蔽内源性和/或外源性应激。
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公开(公告)号：US20090131846A1
公开(公告)日：2009-05-21
申请号：US12358164
申请日：2009-01-22
IPC分类号： A61F13/00
CPC分类号： A61L15/42 , A61L15/44 , A61L15/58 , A61L2300/412 , A61L2300/428
摘要： Devices, bandages, kits and methods are described that can control or regulate the mechanical environment of a wound to ameliorate scar and/or keloid formation. The mechanical environment of a wound includes stress, strain, and any combination of stress and strain. The control of a wound's mechanical environment can be active, passive, dynamic, or static. The devices are configured to be removably secured to a skin surface in proximity to the wound site and shield the wound from endogenous and/or exogenous stress.
摘要翻译： 描述了可以控制或调节伤口的机械环境以改善瘢痕和/或瘢痕疙瘩形成的装置，绷带，试剂盒和方法。 伤口的机械环境包括应力，应变和应力和应变的任何组合。 创伤的机械环境的控制可以是主动的，被动的，动态的或静态的。 这些装置被构造成可移除地固定到靠近伤口部位的皮肤表面，并且将伤口屏蔽内源性和/或外源性应激。
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公开(公告)号：US20120226306A1
公开(公告)日：2012-09-06
申请号：US13411394
申请日：2012-03-02
申请人： Jasper Jackson , John A. Zepeda , Geoffrey C. Gurtner , William R. Beasley , Paul Yock , Keiichiro Ichiryu , Manuel A. Cardona Pamplona , Tor C. Krog , Kemal Levi , Michael T. Longaker , Reinhold H. Dauskardt , Michael T. Cao , Rene Rodriguez
发明人： Jasper Jackson , John A. Zepeda , Geoffrey C. Gurtner , William R. Beasley , Paul Yock , Keiichiro Ichiryu , Manuel A. Cardona Pamplona , Tor C. Krog , Kemal Levi , Michael T. Longaker , Reinhold H. Dauskardt , Michael T. Cao , Rene Rodriguez
IPC分类号： A61B17/00
CPC分类号： A61F13/00038 , A61F13/00 , A61F13/00029 , A61F13/0223 , A61F13/0226 , A61F13/023 , A61F13/0256 , A61F13/0259 , A61F2013/00374 , A61F2013/006
摘要： Devices, kits and methods described herein may be for wound healing, including but not limited to the treatment, amelioration, or prevention of scars and/or keloids. The packaging, manipulation elements, applicator and/or tensioning device maybe used to apply and/or maintain a strain in an elastic dressing.
摘要翻译： 本文所述的装置，试剂盒和方法可用于伤口愈合，包括但不限于治疗，改善或预防瘢痕和/或瘢痕疙瘩。 包装，操作元件，施用器和/或张紧装置可用于在弹性敷料中施加和/或维持应变。
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公开(公告)号：US08168850B2
公开(公告)日：2012-05-01
申请号：US12358162
申请日：2009-01-22
CPC分类号： A61L15/42 , A61L15/44 , A61L15/58 , A61L2300/412 , A61L2300/428
摘要： Devices, bandages, kits and methods are described that can control or regulate the mechanical environment of a wound to ameliorate scar and/or keloid formation. The mechanical environment of a wound includes stress, strain, and any combination of stress and strain. The control of a wound's mechanical environment can be active, passive, dynamic, or static. The devices are configured to be removably secured to a skin surface in proximity to the wound site and shield the wound from endogenous and/or exogenous stress.
摘要翻译： 描述了可以控制或调节伤口的机械环境以改善瘢痕和/或瘢痕疙瘩形成的装置，绷带，试剂盒和方法。 伤口的机械环境包括应力，应变和应力和应变的任何组合。 创伤的机械环境的控制可以是主动的，被动的，动态的或静态的。 这些装置被构造成可移除地固定到靠近伤口部位的皮肤表面，并且将伤口屏蔽内源性和/或外源性应激。
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公开(公告)号：US20120046591A1
公开(公告)日：2012-02-23
申请号：US13089104
申请日：2011-04-18
CPC分类号： A61F13/0243 , A61F13/00051 , A61F13/00059 , A61F13/0233 , A61F2013/00123 , A61F2013/00127 , A61F2013/00153 , A61F2013/00182 , A61F2013/0028 , A61K38/00 , A61K47/64 , A61K47/67 , B82Y5/00 , C07K5/0606 , C07K5/06113 , C07K5/0806 , C07K5/081 , C07K5/1008 , C07K7/02 , C07K9/005 , G01N33/57407 , G01N33/57419 , G01N2333/95 , G01N2500/00
摘要： Devices, bandages, kits and methods are described that can control or regulate the mechanical environment of a wound to ameliorate scar and/or keloid formation. The mechanical environment of a wound includes stress, strain, and any combination of stress and strain. The control of a wound's mechanical environment can be active, passive, dynamic, or static. The devices are configured to be removably secured to a skin surface in proximity to the wound site and shield the wound from endogenous and/or exogenous stress.
摘要翻译： 描述了可以控制或调节伤口的机械环境以改善瘢痕和/或瘢痕疙瘩形成的装置，绷带，试剂盒和方法。 伤口的机械环境包括应力，应变和应力和应变的任何组合。 创伤的机械环境的控制可以是主动的，被动的，动态的或静态的。 这些装置被构造成可移除地固定到靠近伤口部位的皮肤表面，并且将伤口屏蔽内源性和/或外源性应激。
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公开(公告)号：US20110244566A1
公开(公告)日：2011-10-06
申请号：US12931476
申请日：2011-02-01
申请人： Joseph Wu , Michael T. Longaker , Mark A. Kay , Ning Sung , FangJun Jia , Zhi-Ying Chen , Nicholas Panetta , Deepak Gupta
发明人： Joseph Wu , Michael T. Longaker , Mark A. Kay , Ning Sung , FangJun Jia , Zhi-Ying Chen , Nicholas Panetta , Deepak Gupta
CPC分类号： C12N5/0696 , C12N15/85 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/605 , C12N2501/606 , C12N2506/1384 , C12N2510/00 , C12N2800/00 , C12N2800/108 , C12N2800/24
摘要： Human somatic cells are reprogrammed to become induced pluripotent stem cells (iPS cells) by the introduction of a minicircle DNA vector. Cells of interest include adipose stem cells.
摘要翻译： 通过引入小环DNA载体，将人体细胞重新编程成诱导多能干细胞（iPS细胞）。 感兴趣的细胞包括脂肪干细胞。
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公开(公告)号：US09248049B2
公开(公告)日：2016-02-02
申请号：US13089105
申请日：2011-04-18
IPC分类号： A61F13/02 , A61F13/00 , A61K47/48 , B82Y5/00 , C07K5/062 , C07K5/072 , C07K5/083 , C07K5/103 , C07K7/02 , C07K9/00 , G01N33/574 , A61K38/00
CPC分类号： A61F13/0243 , A61F13/00051 , A61F13/00059 , A61F13/0233 , A61F2013/00123 , A61F2013/00127 , A61F2013/00153 , A61F2013/00182 , A61F2013/0028 , A61K38/00 , A61K47/64 , A61K47/67 , B82Y5/00 , C07K5/0606 , C07K5/06113 , C07K5/0806 , C07K5/081 , C07K5/1008 , C07K7/02 , C07K9/005 , G01N33/57407 , G01N33/57419 , G01N2333/95 , G01N2500/00
摘要： Devices, bandages, kits and methods are described that can control or regulate the mechanical environment of a wound to ameliorate scar and/or keloid formation. The mechanical environment of a wound includes stress, strain, and any combination of stress and strain. The control of a wound's mechanical environment can be active, passive, dynamic, or static. The devices are configured to be removably secured to a skin surface in proximity to the wound site and shield the wound from endogenous and/or exogenous stress.
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公开(公告)号：US08389791B2
公开(公告)日：2013-03-05
申请号：US13089104
申请日：2011-04-18
CPC分类号： A61F13/0243 , A61F13/00051 , A61F13/00059 , A61F13/0233 , A61F2013/00123 , A61F2013/00127 , A61F2013/00153 , A61F2013/00182 , A61F2013/0028 , A61K38/00 , A61K47/64 , A61K47/67 , B82Y5/00 , C07K5/0606 , C07K5/06113 , C07K5/0806 , C07K5/081 , C07K5/1008 , C07K7/02 , C07K9/005 , G01N33/57407 , G01N33/57419 , G01N2333/95 , G01N2500/00
摘要： Devices, bandages, kits and methods are described that can control or regulate the mechanical environment of a wound to ameliorate scar and/or keloid formation. The mechanical environment of a wound includes stress, strain, and any combination of stress and strain. The control of a wound's mechanical environment can be active, passive, dynamic, or static. The devices are configured to be removably secured to a skin surface in proximity to the wound site and shield the wound from endogenous and/or exogenous stress.
摘要翻译： 描述了可以控制或调节伤口的机械环境以改善瘢痕和/或瘢痕疙瘩形成的装置，绷带，试剂盒和方法。 伤口的机械环境包括应力，应变和应力和应变的任何组合。 创伤的机械环境的控制可以是主动的，被动的，动态的或静态的。 这些装置被构造成可移除地固定到靠近伤口部位的皮肤表面，并且将伤口屏蔽内源性和/或外源性应激。
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公开(公告)号：US20120226214A1
公开(公告)日：2012-09-06
申请号：US13411443
申请日：2012-03-02
申请人： Geoffrey C. Gurtner , Michael T. Longaker , Reinhold H. Dauskardt , Paul Yock , John A. Zepeda , Kenneth N. Horne , Bankim H. Mehta , Michael H. Rosenthal , Joseph Rimsa , Sergio Salinas , Melanie Harris , Greg Spooner , Kin Chan
发明人： Geoffrey C. Gurtner , Michael T. Longaker , Reinhold H. Dauskardt , Paul Yock , John A. Zepeda , Kenneth N. Horne , Bankim H. Mehta , Michael H. Rosenthal , Joseph Rimsa , Sergio Salinas , Melanie Harris , Greg Spooner , Kin Chan
IPC分类号： A61F13/00
CPC分类号： A61F13/00038 , A61F13/00 , A61F13/00029 , A61F13/0223 , A61F13/0226 , A61F13/023 , A61F13/0256 , A61F13/0259 , A61F2013/00374 , A61F2013/006
摘要： The methods, procedures, kits, and devices described herein assist with the healing process of tissue that was previously or simultaneously treated for a therapeutic or cosmetic effect. The methods, procedures, kits, and devices described herein can also provide temporary simulated results of a cosmetic procedure to allow for visual assessment to select the type of procedure or for treatment planning in advance of the surgical procedure.
摘要翻译： 本文描述的方法，程序，试剂盒和装置有助于治疗或美容效果先前或同时治疗的组织的愈合过程。 本文所述的方法，程序，试剂盒和装置还可以提供美容程序的临时模拟结果，以允许视觉评估在外科手术之前选择手术类型或治疗计划。
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