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    Needle guide system and medical intervention system
    11.
    发明授权
    Needle guide system and medical intervention system 有权

    公开(公告)号：US10376235B2

    公开(公告)日：2019-08-13

    申请号：US15385877

    申请日：2016-12-21

    申请人： Industrial Technology Research Institute ,  National Taiwan University Hospital

    发明人： Wan-Hsin Hsieh ,  Hui-Hsin Lu ,  Chih-Yuan Wang

    IPC分类号： A61B8/08 ,  A61B5/06 ,  A61B8/00

    摘要： A needle guide system is provided. The needle guide system includes a puncture device, an ultrasound transducer, a first orientation detector, a second orientation detector, a proximity detector and a processor. The ultrasound transducer is configured to obtain an ultrasound image. The first orientation detector is disposed on the puncture device, and the second orientation detector is disposed on the ultrasound transducer. The proximity detector is disposed on at least one of the puncture device and the ultrasound transducer, configured to obtain a relative distance between the puncture device and the ultrasound transducer. The processor is configured to obtain a spatial relationship between the puncture device and the ultrasound transducer by using the first orientation detector, the second orientation detector, and the proximity detector, and predict a trajectory of the puncture device in the ultrasound image according to the spatial relationship. In addition, a medical intervention system is also provided.

    Sensing bone fixing element
    13.
    发明授权
    Sensing bone fixing element 有权

    公开(公告)号：US10052063B2

    公开(公告)日：2018-08-21

    申请号：US14985458

    申请日：2015-12-31

    申请人： National Chiao Tung University ,  National Taiwan University Hospital Hsin-Chu Branch

    发明人： Wen-Syang Hsu ,  Tze-Hong Wong ,  Asher Sun ,  Sung-Yueh Wu

    IPC分类号： A61B5/00 ,  A61B17/70 ,  A61B5/07

    CPC分类号： A61B5/4851 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/686 ,  A61B17/7032 ,  A61B2562/0261

    摘要： A sensing bone fixing element includes a fixing portion, a fastening portion, a capacitor structure, and a coil. The fastening portion is fixed to the fixing portion and suitable for being fastened to a bone. The fastening portion passes through the capacitor structure which has a capacitance value and includes a first conductive layer, a second conductive layer, and an elastic dielectric layer. The first conductive layer leans against the fixing portion, the second conductive layer leans against the bone, and the elastic dielectric layer is located between the first conductive layer and the second conductive layer. The coil has an inductance value, and two ends of the coil are respectively connected to the first conductive layer and the second conductive layer. The coil receives a detection radio frequency (RF) signal and generates a responding RF signal according to variations in the capacitance value and the inductance value.

    METHODS OF ANALYZING PRESSURE DISTRIBUTION ROW BY ROW
    14.
    发明申请
    METHODS OF ANALYZING PRESSURE DISTRIBUTION ROW BY ROW 审中-公开

    公开(公告)号：US20170131159A1

    公开(公告)日：2017-05-11

    申请号：US15147185

    申请日：2016-05-05

    申请人： NATIONAL TAIWAN UNIVERSITY HOSPITAL

    发明人： Wei-Li HSI

    IPC分类号： G01L1/00

    CPC分类号： G01L1/005 ,  G01L1/146 ,  G01L1/205

    摘要： The present invention provides a method of calculating an average moment arm row by row, comprising measuring the pressure an object exerts on a pressure sensor matrix, obtaining the pressure values and moment arms for each sensor of the sensor matrix in a time sequence, and calculating an average moment arm for each row of the sensor matrix, to reveal a row of sensors whose pressure is distributed farthest from or closest to the reference axis over time. The present invention also provides a method of calculating a percentage of average moment arm row by row to reveal the relative pressure distribution in a row between the sensors sensing pressure closest to and farthest from the reference axis. The present invention further provides a method of calculating a change of average moment arm and a change of percentage of average moment arm over time row by row.

    Device of Automatic Mechanical Wound Opener for Head and Neck Surgery
    16.
    发明申请
    Device of Automatic Mechanical Wound Opener for Head and Neck Surgery 有权
    头颈外科自动机械伤口开启装置

    公开(公告)号：US20150100078A1

    公开(公告)日：2015-04-09

    申请号：US14047104

    申请日：2013-10-07

    申请人： National Taiwan University Hospital

    发明人： Tsung-Lin Yang

    IPC分类号： A61B17/02

    CPC分类号： A61B17/0206 ,  A61B90/50 ,  A61B2090/571

    摘要： A wound opener is provided. An operative field can be created through head/neck soft tissues for introducing the endoscopes and robotic surgical tools. An incision size can be properly adjusted. Thus, endoscopes, robotic arms or other devices can be smoothly introduced into the operative field to evaluate and treat lesions of head and neck soft tissues. Hence, the present invention facilitates surgical procedure, reduces wound size and effectively conceals wound to make it become invisible.

    摘要翻译： 提供伤口开启器。 可以通过头/颈软组织产生用于引入内窥镜和机器人手术工具的手术领域。 切口尺寸可以适当调整。 因此，可以将内窥镜，机器人手臂或其他装置平滑地引入到手术领域中，以评估和治疗头颈软组织的损伤。 因此，本发明有助于外科手术，减少伤口尺寸并有效地隐藏伤口以使其变得不可见。

    Method for Analyzing Apoptosis Inducing Factor-2
    17.
    发明申请
    Method for Analyzing Apoptosis Inducing Factor-2 审中-公开
    分析细胞凋亡诱导因子-2的方法

    公开(公告)号：US20130323750A1

    公开(公告)日：2013-12-05

    申请号：US13903972

    申请日：2013-05-28

    申请人： National Taiwan University Hospital.

    发明人： Kuan-Tun Wu ,  Ann Chen ,  Shuk-Man Ka

    IPC分类号： G01N33/68

    CPC分类号： G01N33/6872 ,  G01N33/68 ,  G01N2333/902 ,  G01N2800/347

    摘要： A method for analyzing apoptosis inducing factor-2 (AIF-2) is disclosed, which has not been found in urine samples of human patients with chronic kidney disease, to establish AIF-2 as a non-invasive biomarker for chronic kidney disease. The method includes: collecting a plurality of urine samples; conducting western blot for each urine sample for detecting the AIF-2 protein content in each urine sample; and conducting statistical analysis of the AIF-2 protein content in each urine sample to establish AIF-2 as a biological marker for chronic kidney disease.

    摘要翻译： 公开了一种分析凋亡诱导因子-2（AIF-2）的方法，其在慢性肾脏疾病患者的尿液样本中尚未发现，以建立AIF-2作为慢性肾脏疾病的非侵入性生物标志物。 该方法包括：收集多个尿样; 对每个尿样进行蛋白印迹检测，以检测每个尿样中的AIF-2蛋白含量; 并对每个尿液样品中的AIF-2蛋白质含量进行统计分析，建立AIF-2作为慢性肾脏疾病的生物学标志物。

    Object detection method and convolution neural network for the same
    20.
    发明授权
    Object detection method and convolution neural network for the same 有权

    公开(公告)号：US11651588B1

    公开(公告)日：2023-05-16

    申请号：US16970628

    申请日：2020-06-05

    申请人： AETHERAI IP HOLDING LLC ,  NATIONAL TAIWAN UNIVERSITY HOSPITAL

    发明人： Chao-Yuan Yeh ,  Wen-Chien Chou ,  Cheng-Kun Yang

    IPC分类号： G06V10/82 ,  G06T3/40 ,  G06V10/77

    CPC分类号： G06V10/82 ,  G06T3/4046 ,  G06V10/7715

    摘要： Disclosed are an object detection method and a convolution neural network. The method is performed through hierarchical architecture of the CNN and includes extracting groups of augmented feature maps from an input image through a backbone and two other groups of feature maps, identifying positive and negative samples with an IOU-based sampling scheme to be proposals for foreground and background through a proposal-sampling classifier, mapping the proposals to regions on the groups of augmented feature maps through the region proposal module, pooling the regions to fixed scale feature maps based on ROI aligning, fusing the fixed scale feature maps, and flattening the fused feature maps to generate an ROI feature vector through an ROI aligner for object classification and box regression. Because extracted features in the groups of augmented feature maps range from spatially-rich features to semantically-rich features, enhanced performance in object classification and box regression can be secured.