公开(公告)号：US20090048461A1

公开(公告)日：2009-02-19

申请号：US11571033

申请日：2005-06-21

Applicant: Naresh Kumar

Inventor： Naresh Kumar

IPC: C07C69/66 ,  C07C45/65

CPC classification number: C11D3/48 ,  A01N31/02 ,  A01N35/02 ,  A61K8/35 ,  A61Q5/02 ,  A61Q19/10 ,  C07C45/676 ,  C07C49/227 ,  C07C49/235 ,  C11D3/24

Abstract: The present invention provides a method for the preparation of compounds of formula (II). The invention also provides novel compounds of formula (II) and their use in medical, scientific and/or biological applications.

Abstract translation: 本发明提供了制备式（II）化合物的方法。 本发明还提供新的式（II）化合物及其在医学，科学和/或生物应用中的用途。

公开(公告)号：US07488494B2

公开(公告)日：2009-02-10

申请号：US10704385

申请日：2003-11-07

Applicant: Andrew Heaton ,  Naresh Kumar ,  Graham Edmund Kelly ,  Alan Husband

Inventor： Andrew Heaton ,  Naresh Kumar ,  Graham Edmund Kelly ,  Alan Husband

IPC: A61K47/22 ,  A61K31/47 ,  C07D335/04 ,  C07D311/04

CPC classification number: C07D311/26 ,  A23L33/10 ,  A23L33/11 ,  A23V2002/00 ,  C07D311/36 ,  C07D311/38 ,  C07D311/58 ,  C07D471/06 ,  A23V2250/2116 ,  A23V2200/30

Abstract: Isoflavone compounds are described and recommended as therapeutic agents. Exemplified and preferred compounds are (a). Indications show compounds have good competitive binding to estrogen receptors. This is exemplified

Abstract translation: 描述和推荐异黄酮化合物作为治疗剂。 示例性和优选的化合物是（a）。 适应症显示化合物与雌激素受体具有良好的竞争性结合。 这是例证

公开(公告)号：US20080292736A1

公开(公告)日：2008-11-27

申请号：US12011582

申请日：2008-01-28

Applicant: Ghulam Nabi Qazi ,  Kasturi Lal Bedi ,  Rakesh Kamal Johri ,  Manoj Kumar Tikoo ,  Ashok Kumar Tikoo ,  Subhash Chandra Sharma ,  Tasaduaq Abdullah ,  Om Parkash Suri ,  Bishan Datt Gupta ,  Krishan Avtar Suri ,  Naresh Kumar Satti ,  Ravi Kant Khajuria

Inventor： Ghulam Nabi Qazi ,  Kasturi Lal Bedi ,  Rakesh Kamal Johri ,  Manoj Kumar Tikoo ,  Ashok Kumar Tikoo ,  Subhash Chandra Sharma ,  Tasaduaq Abdullah ,  Om Parkash Suri ,  Bishan Datt Gupta ,  Krishan Avtar Suri ,  Naresh Kumar Satti ,  Ravi Kant Khajuria

IPC: A61K36/23 ,  A61K36/9068

CPC classification number: A61K31/7048 ,  A61K31/496 ,  A61K31/497 ,  A61K36/23 ,  A61K36/67 ,  A61K36/9068 ,  A61K2300/00

Abstract: The present invention relates to the use of extracts of Carum carvi as bioenhancers, either alone or in combination with piperine or Zingiber officinale extract to improve the bioavailability of a wide variety of drugs.

Abstract translation: 本发明涉及Carum carvi的提取物作为生物降解剂，单独使用或与胡椒碱或姜黄素提取物组合以提高各种药物的生物利用度。

公开(公告)号：US20070130616A1

公开(公告)日：2007-06-07

申请号：US11296027

申请日：2005-12-06

Applicant: Raymond Ng ,  Ganesh Kirti ,  Thomas Keefe ,  Naresh Kumar

Inventor： Raymond Ng ,  Ganesh Kirti ,  Thomas Keefe ,  Naresh Kumar

IPC: H04L9/32

CPC classification number: G06F21/6227 ,  G06F2221/2105 ,  G06F2221/2149 ,  H04L63/168

Abstract: Systems, methods, and machine-readable media are disclosed for providing dynamic and/or conditional constraints on queries based on an external security policy. In one embodiment, a method is provided which comprises receiving from a user a request to access a resource. A condition clause can be read from a grant statement defined in the security policy. The grant statement can define permission for the user to access the requested resource. In some cases, the grant statement can comprise a Java Authentication and Authorization Service (JAAS) grant statement. A query associated with the requested access can be modified based on the permission granted to the user. The modified query can then be made to perform the requested access.

Abstract translation: 公开了系统，方法和机器可读介质，用于基于外部安全策略来提供关于查询的动态和/或条件约束。 在一个实施例中，提供了一种方法，其包括从用户接收访问资源的请求。 可以从安全策略中定义的授权语句读取条件子句。 授权语句可以定义用户访问所请求资源的权限。 在某些情况下，授权语句可以包含Java认证和授权服务（JAAS）授权语句。 可以基于授予用户的权限来修改与请求的访问相关联的查询。 然后可以使修改的查询执行请求的访问。

公开(公告)号：US20070032666A1

公开(公告)日：2007-02-08

申请号：US11414552

申请日：2006-05-01

Applicant: Roger Read ,  Naresh Kumar

Inventor： Roger Read ,  Naresh Kumar

IPC: C07D305/12

CPC classification number: C08F20/00 ,  A01N43/08 ,  C07D307/58 ,  C08F24/00

Abstract: The present invention relates to the side chain functionalization of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones) and their synthetic analogues, that yields fimbrolides substituted with a halogen, an oxygen or a nitrogen functionality in the alkyl chain, especially fimbrolide alcohols, caboxylate and sulfinate and sulfonate esters, ethers, aldehydes, ketones, acids, amides, nitro derivatives, hydrophobic, hydrophilic and fluorophilic alkyl derivatives and polymers.

Abstract translation: 本发明涉及福滨洛尔（卤代3-烷基-5-亚甲基-2（5H） - 呋喃酮）及其合成类似物的侧链官能化，其产生在烷基中被卤素，氧或氮官能团取代的菲莫拉林 链，特别是曲芬洛尔醇，卡波西铵和亚磺酸盐和磺酸酯，醚，醛，酮，酸，酰胺，硝基衍生物，疏水性，亲水和氟烷基衍生物和聚合物。

公开(公告)号：US20070010568A1

公开(公告)日：2007-01-11

申请号：US10544520

申请日：2003-02-07

Applicant: Anita Mehta ,  Bruhaspathy Miriyala ,  Naresh Kumar ,  Jang Gupta

Inventor： Anita Mehta ,  Bruhaspathy Miriyala ,  Naresh Kumar ,  Jang Gupta

IPC: A61K31/403 ,  C07D209/02

CPC classification number: C07D471/08

Abstract: This invention relates to derivatives of substituted azabicyclo hexanes. The compound of this invention can function as muscarinic receptor antagonists, and can be used for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to a process for the preparation of compounds of the present invention, pharmaceutical compositions containing the compounds of the present invention and the methods of treating the diseases mediated through muscarinic receptors.

Abstract translation: 本发明涉及取代的氮杂双环己烷的衍生物。 本发明化合物可用作毒蕈碱受体拮抗剂，可用于治疗通过毒蕈碱受体介导的呼吸道，尿路和胃肠道系统的各种疾病。 本发明还涉及制备本发明化合物的方法，含有本发明化合物的药物组合物以及通过毒蕈碱受体介导的疾病的治疗方法。

公开(公告)号：US20060247225A1

公开(公告)日：2006-11-02

申请号：US10543585

申请日：2003-01-23

Applicant: Anita Mehta ,  Arundutt Silamkoti ,  Naresh Kumar ,  Jang Gupta

Inventor： Anita Mehta ,  Arundutt Silamkoti ,  Naresh Kumar ,  Jang Gupta

IPC: A61K31/55 ,  A61K31/46

CPC classification number: C07D401/04 ,  C07D209/52 ,  C07D401/06 ,  C07D403/04 ,  C07D405/04 ,  C07D405/06 ,  C07D409/04

Abstract: This invention generally relates to derivatives of 3,6 disubstituted azabicyclo hexanes. The compounds of this invention can function as muscarinic receptor antagonists and can be used for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to pharmaceutical compositions containing the compounds of the present invention and the methods of treating the diseases mediated through muscarinic receptors.

公开(公告)号：US20060106220A1

公开(公告)日：2006-05-18

申请号：US11300976

申请日：2005-12-14

Applicant: Andrew Heaton ,  Naresh Kumar ,  Graham Kelly ,  Alan Husband

Inventor： Andrew Heaton ,  Naresh Kumar ,  Graham Kelly ,  Alan Husband

IPC: A61K31/4745 ,  C07D471/04 ,  C07D405/02 ,  C07D409/02 ,  C07D401/02 ,  A61K31/4709

CPC classification number: C07D311/26 ,  A23L33/10 ,  A23L33/11 ,  A23V2002/00 ,  C07D311/36 ,  C07D311/38 ,  C07D311/58 ,  C07D471/06 ,  A23V2250/2116 ,  A23V2200/30

Abstract: Isoflavone compounds and analogues thereof, compositions containing same and therapeutic methods of treatment involving same are described.

Abstract translation: 描述异黄酮化合物及其类似物，含有其的组合物和涉及其的治疗方法。

公开(公告)号：US20050215772A1

公开(公告)日：2005-09-29

申请号：US10525231

申请日：2003-08-19

Applicant: Naresh Kumar

Inventor： Naresh Kumar

IPC: A01N43/08 ,  A01N43/36 ,  A61L2/16 ,  A61L12/14 ,  A61P17/10 ,  A61P31/00 ,  A61P33/00 ,  C07D207/38 ,  C07D207/44 ,  C07D307/34 ,  C07D307/60 ,  C07D307/66 ,  C07H19/22 ,  C07D207/24 ,  C07H19/048

CPC classification number: C07D207/44 ,  A01N43/08 ,  A01N43/36 ,  A61L2/16 ,  A61L12/14 ,  C07D207/38 ,  C07D307/34 ,  C07D307/60 ,  C07D307/66

Abstract: Novel synthesis methods, to the products of such novel methods, and to uses of these products. In particular, the present invention provides methods for the reactions of furanones, in particular fimbrolides, with amines. The invention has particular application in the synthesis of halogenated 1,5-dihydro-pyrrol-2-one, 5-halomethylene substituted 1,5-dihydropyrrol-2-ones (lactam analogues of fimbriolides), 5-amino substituted furanones and 5-aminomethylene-2(5H)-furanones and their synthetic analogues. The invention also relates to novel compounds and uses thereof.

Abstract translation: 新型合成方法，对这些新方法的产品，以及这些产品的用途。 特别地，本发明提供了呋喃酮，特别是福滨洛尔与胺反应的方法。 本发明特别适用于卤代1,5-二氢 - 吡咯-2-酮，5-卤代亚甲基取代的1,5-二氢吡咯-2-酮（呋喃草醚的内酰胺类似物），5-氨基取代的呋喃酮和5- 氨基亚甲基-2（5H） - 呋喃酮及其合成类似物。 本发明还涉及新化合物及其用途。

公开(公告)号：US06913772B2

公开(公告)日：2005-07-05

申请号：US10735437

申请日：2003-12-11

Applicant: Ghulam Nabi Qazi ,  Bupinder Singh Jaggi ,  Bal Krishan Chandan ,  Krishan Avtar Suri ,  Naresh Kumar Satti ,  Rakesh Maurya ,  Lila Ram Manhas ,  Ashwani Kumar ,  Bal Krishan Kapahi

Inventor： Ghulam Nabi Qazi ,  Bupinder Singh Jaggi ,  Bal Krishan Chandan ,  Krishan Avtar Suri ,  Naresh Kumar Satti ,  Rakesh Maurya ,  Lila Ram Manhas ,  Ashwani Kumar ,  Bal Krishan Kapahi

IPC: A01N25/00 ,  A01N27/00 ,  A01N65/00 ,  A61K31/4745 ,  A61K31/70 ,  A61K36/27 ,  A61K35/78

CPC classification number: A61K36/27 ,  Y10S514/885 ,  Y10S514/893 ,  Y10S514/894

Abstract: The present invention relates to a composition useful for hepatoprotection, said composition comprising polar extract of plant Cryptolepis Buchanani and/or fractions of the said extract, and optionally pharmaceutically acceptable additives and a method of producing said composition and also a method of treating a subject using said composition.

Abstract translation: 本发明涉及一种可用于肝保护的组合物，所述组合物包含植物Cryptolepis Buchanani的极性提取物和/或所述提取物的级分，和任选的药学上可接受的添加剂和制备所述组合物的方法，以及使用 所说的组合。