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公开(公告)号：US12300313B2
公开(公告)日：2025-05-13
申请号：US17580862
申请日：2022-01-21
Inventor： Farnood Merrikh Bayat , Xinjie Guo , Dmitri Strukov , Nhan Do , Hieu Van Tran , Vipin Tiwari , Mark Reiten
IPC: G11C11/54 , G06F3/06 , G06N3/04 , G06N3/045 , G06N3/063 , G11C16/08 , G11C16/12 , G11C16/16 , G11C16/34 , G11C29/38
Abstract: An artificial neural network device that utilizes one or more non-volatile memory arrays as the synapses. The synapses are configured to receive inputs and to generate therefrom outputs. Neurons are configured to receive the outputs. The synapses include a plurality of memory cells, wherein each of the memory cells includes spaced apart source and drain regions formed in a semiconductor substrate with a channel region extending there between, a floating gate disposed over and insulated from a first portion of the channel region and a non-floating gate disposed over and insulated from a second portion of the channel region. Each of the plurality of memory cells is configured to store a weight value corresponding to a number of electrons on the floating gate. The plurality of memory cells are configured to multiply the inputs by the stored weight values to generate the outputs.
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公开(公告)号：US12298524B2
公开(公告)日：2025-05-13
申请号：US17314895
申请日：2021-05-07
Applicant: The Regents of the University of California
Inventor： Luat Vuong , Baurzhan Muminov , Ji Feng
Abstract: Described herein are imaging devices and associated methods. Devices and methods are described that include a plurality of topological phase modulators. In one example, the plurality of topological phase modulators includes an array of spiral vortices. Devices and methods are described that include a neural network to reconstruct images using data from the plurality of topological phase modulators.
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公开(公告)号：US12297241B2
公开(公告)日：2025-05-13
申请号：US17257951
申请日：2019-07-03
Applicant: The Regents of the University of California
Inventor： Kun Zhang , Yan Wu , Amir Dailamy , Prashant Mali , Daniella McDonald , Udit Parekh , Michael Hu
Abstract: This disclosure relates to methods, polynucleotides, vectors, viral particles, cells, and systems or the engineering of human tissues. One aspect of the disclosure relates to using lineage-specific miRNA binding molecules to bias tissue lineage. Another aspect of the disclosure relates to using lineage-specific transcription factor overexpression to bias tissue lineage.
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公开(公告)号：US20250143596A1
公开(公告)日：2025-05-08
申请号：US18694371
申请日：2022-09-23
Applicant: The Regents of the University of California
Inventor： Jun CHEN
Abstract: The present embodiments relate generally to a soft system for producing a giant magnetoelastic effect. In some embodiments, the soft system is composed of platinum-catalyzed silicone polymer matrix and neodymium-iron-boron nanomagnets. The soft system shows up to four times more enhancement of the magnetomechanical coupling factor (T/Pa) than traditional rigid counterparts owing to a distinct physical mechanism. In embodiments, the giant magnetoelastic effect is coupled with magnetic induction to implement a soft magnetoelastic generator (MEG) as an approach to biomechanical energy conversion, a technology that was heretofore conventionally challenged by low current, high internal impedance, and low water/humidity resistance for decent operation stability. This new method of biomechanical-to-electrical conversion is intrinsically waterproof since the magnetic fields are able to penetrate water with negligible intensity loss. Thus, it was demonstrated to work stably on wet skin or in body fluids without any encapsulation, opening up alternative avenues for practical human-body centered energy, sensing, and therapeutic applications.
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公开(公告)号：US12290659B2
公开(公告)日：2025-05-06
申请号：US18078857
申请日：2022-12-09
Applicant: The Regents of the University of California , Government of the United States as represented by the Secretary of the Air Force
Inventor： Michael Austin Johnson , Lucas Paul Neff , Timothy Williams
Abstract: Systems and methods for Endovascular Perfusion Augmentation for Critical Care (EPACC) are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient. The system may also include a catheter controller unit that causes the expandable aortic blood flow regulation device to expand and contract to restrict blood flow through the aorta. The system may also include one or more sensors for measuring physiological information indicative of blood flow through the aorta, and a non-transitory computer readable media having instructions stored thereon, wherein the instructions, when executed by a processor coupled to the one or more sensors, cause the processor to compare the measured physiological information with a target physiological range associated with blood flow through the aorta such that the catheter controller unit automatically adjusts expansion and contraction of the expandable aortic blood flow regulation device to adjust an amount of blood flow through the aorta if the measured physiological information falls outside the target physiological range.
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Patent Agency Ranking
公开(公告)号：US20250140893A1
公开(公告)日：2025-05-01
申请号：US18930823
申请日：2024-10-29
Inventor： Jeongbeom LEE , Min-Sang SONG , Yu-Ting CHEN , Ying Shirley MENG
IPC: H01M10/04 , H01M10/0525 , H01M10/44 , H01M10/615 , H01M50/105
Abstract: A battery cell pressing system may include a sealed case having an internal chamber, the sealed case including at least one window to allow visual inspection of the internal chamber; a pouch-type battery cell disposed within the internal chamber of the sealed case; a fluid filling the internal chamber and surrounding the pouch-type battery cell; a fluid entrance in fluid communication with the internal chamber; a pressing member configured to adjust a pressure of the fluid within the internal chamber such that the pressure at which the fluid presses the pouch-type battery cell is approximately 1 MPa to 10 MPa; a heater configured to heat the fluid within the internal chamber; and a pressure measuring member configured to measure the pressure within the internal chamber. The fluid isotropically presses the pouch-type battery cell during at least one of charging and discharging of the pouch-type battery cell.
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17.发明申请公开(公告)号：US20250139446A1
公开(公告)日：2025-05-01
申请号：US18925783
申请日：2024-10-24
Applicant: The Regents of The University of California
Inventor： Guann Pyng Li , Yutian Ren
IPC: G06N3/088
Abstract: A system for automatically self-labeling a digital dataset includes a first sensor for generating a first data stream, a second sensor for collecting information to generate a second data stream, and a causal model manager (CMM). The CMM is configured to determine a first causal event from a first data segment of the first data stream, and a causal relation between the first causal event and a second data segment selected from the second data stream. The system further includes (a) an interactive time model for determining an interaction time between the first and second data segments, and (b) a self-labeling subsystem configured to derive a label from the second data segment, associate the first data segment with the derived label, form a self-labeled data pair from the associated first data segment and the derived label, and automatically annotate the self-labeled data pair with the interaction time.
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公开(公告)号：US20250138633A1
公开(公告)日：2025-05-01
申请号：US18694280
申请日：2022-09-23
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Nader Fathy , Patrick Mercier
Abstract: A method for obtaining neural signals from a neural signal sensor includes extracting sensor offset from a neural input signal. Sensor offset is removed from N-channels that share a single amplifier. The neural input signal is acquired from the analog domain by neural electrodes with varying DC-offset and the method includes multiplexing the N-channels via a time divisional multiple access procedure into a single neural amplifier An integrated digitally assisted neural recording system includes an analog multiplexer structured to receive N-channels and to multiplex the N-Channels into a single neural amplifier. A feedback loop is configured to cancel electrode offset voltage in the digital domain by generating electrode offset voltage samples and adding delay to align each electrode offset voltage sample to be subtracted at the neural amplifier in the analog domain.
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公开(公告)号：US20250138296A1
公开(公告)日：2025-05-01
申请号：US18721509
申请日：2023-01-13
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Aydogan Ozcan , Deniz Mengu
Abstract: Quantitative phase imaging (QPI) is a label-free computational imaging technique that provides optical path length information of objects. Here, a diffractive QPI network architecture is disclosed that can synthesize the quantitative phase image of an object by converting the input phase information of a scene or object(s) into intensity variations at the output plane. A diffractive QPI network is a specialized all-optical device designed to perform a quantitative phase-to-intensity transformation through passive diffractive/reflective surfaces that are spatially engineered using deep learning and image data. Forming a compact, all-optical network that axially extends only ˜200-300λ (λ=illumination wavelength), this framework replaces traditional QPI systems and related digital computational burdens with a set of passive substrate layers. All-optical diffractive QPI networks can potentially enable power-efficient, high frame-rate and compact phase imaging systems that might be useful for various applications, including, e.g., on-chip microscopy and sensing.
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20.发明申请公开(公告)号：US20250137036A1
公开(公告)日：2025-05-01
申请号：US18936581
申请日：2024-11-04
Applicant: The Regents of the University of California
Inventor： Drew Hall , Chung-Lun Hsu , Alexander Sun , Yunting Zhao , Eliah Aronoff-Spencer
IPC: C12Q1/6825 , G01N27/02
Abstract: Disclosed are biosensor devices, systems, and methods for point-of-care applications. In some aspects, a biosensor system includes a biosensor chip device to measure impedance at an electrode-electrolyte interface, which includes an electrochemical sensor comprising a first electrode including a functionalization layer exposing a molecular binding site to bind a target molecule for detection and a second electrode that does not include the binding site, and an electronic circuit unit corresponding to each electrode of the electrochemical sensor including a transimpedance amplifier, a phase detector to determine a relative phase shift in the detected electrical signal caused by an impedance change from a binding event of the target molecule at the molecular binding site, and a time-to-digital converter to quantize and average phase data points in time to remove uncorrelated noise from the detected electrical signal; and a signal generator to produce an electrical excitation signal applied across the electrode-electrolyte interface.
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