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11.发明申请ELECTROSTATIC-ASSISTED FIBER SPINNING METHOD AND PRODUCTION OF HIGHLY ALIGNED AND PACKED HOLLOW FIBER ASSEMBLY AND MEMBRANE 有权静电辅助纤维纺丝方法和高对比和包装中空纤维组件和膜的生产公开(公告)号：US20110264235A1
公开(公告)日：2011-10-27
申请号：US12764692
申请日：2010-04-21
Applicant: CHIEN-CHUNG CHEN , JEN-CHANG YANG , JEN-CHIEH LU , SHENG-YANG LEE
Inventor： CHIEN-CHUNG CHEN , JEN-CHANG YANG , JEN-CHIEH LU , SHENG-YANG LEE
CPC classification number: D01D5/0069 , A61F2/06 , B01D61/147 , B01D69/08 , B01D2323/39 , D01D5/24 , D01F6/625 , D01F8/14 , Y10T428/249924
Abstract: The invention provides a highly aligned and closely packed hollow fiber assembly, wherein the assemblies of fibrous membrane has a width-to-fiber diameter ratio (W/d) larger than 10 and the orientation of the fibers is no larger than +/−10°. Also provided is an electrospinning process for the preparation of the fiber assembly of the invention and its applications.
Abstract translation: 本发明提供了一种高度排列紧密的中空纤维组件，其中纤维膜的组件具有大于10的宽度与纤维直径之比（W / d），并且纤维的取向不大于+/- 10 °。 还提供了用于制备本发明的纤维组件及其应用的静电纺丝方法。
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公开(公告)号：US20090220919A1
公开(公告)日：2009-09-03
申请号：US12191628
申请日：2008-08-14
Applicant: Jen-Chang Yang , Yu-Lin Huang , Hongda Wu , Yen Cheng Yang , Sheng-Yang Lee
Inventor： Jen-Chang Yang , Yu-Lin Huang , Hongda Wu , Yen Cheng Yang , Sheng-Yang Lee
CPC classification number: A61Q11/00 , A61K8/22 , A61K8/66 , A61K8/90 , A61K8/97 , A61K2800/522 , A61K2800/88 , A61K2800/882
Abstract: This invention is related to a kind of teeth bleaching formulation containing the vegetative enzymes extracted from plant tubers with extensively applications in cosmetic dentistry. The enzymes are susceptible to promote the decomposition (dissociation) of peroxide compounds, thus the intermediate hydroxyl free radicals are generated to turn the unpleasant stained tooth into light or colorless appearance effectively. The composition of a whitening gel may comprising 2˜50 wt % of hydrogen peroxide, 0.003˜3 wt % vegetative enzyme extract, and transferring to alkalinity approximately pH 8˜13 to achieve the high efficiency dental bleaching usage.
Abstract translation: 本发明涉及一种含有从植物块茎中提取的营养酶的牙齿漂白制剂，在美容牙科中广泛应用。 酶易于促进过氧化物化合物的分解（解离），因此产生中间羟基自由基以有效地将令人不快的染色牙齿变成光或无色的外观。 美白凝胶的组成可以包含2〜50重量％的过氧化氢，0.003〜3重量％的营养酶提取物，并转移至碱度约pH 8〜13，以达到高效率的牙齿漂白用途。
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13.发明授权Electrostatic-assisted fiber spinning method and production of highly aligned and packed hollow fiber assembly and membrane 有权静电辅助纤维纺丝方法和高度排列和中空纤维组装和膜的生产公开(公告)号：US09139935B2
公开(公告)日：2015-09-22
申请号：US12764692
申请日：2010-04-21
Applicant: Chien-Chung Chen , Jen-Chang Yang , Jen-Chieh Lu , Sheng-Yang Lee
Inventor： Chien-Chung Chen , Jen-Chang Yang , Jen-Chieh Lu , Sheng-Yang Lee
CPC classification number: D01D5/0069 , A61F2/06 , B01D61/147 , B01D69/08 , B01D2323/39 , D01D5/24 , D01F6/625 , D01F8/14 , Y10T428/249924
Abstract: The invention provides a highly aligned and closely packed hollow fiber assembly, wherein the assemblies of fibrous membrane has a width-to-fiber diameter ratio (W/d) larger than 10 and the orientation of the fibers is no larger than +/−10°. Also provided is an electrospinning process for the preparation of the fiber assembly of the invention and its applications.
Abstract translation: 本发明提供了一种高度排列紧密的中空纤维组件，其中纤维膜的组件具有大于10的宽度与纤维直径之比（W / d），并且纤维的取向不大于+/- 10 °。 还提供了用于制备本发明的纤维组件及其应用的静电纺丝方法。
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14.发明授权Composite of amorphous calcium phosphate/calcium sulfate hemihydrate (CSH/ACP) for bone implantation and process for producing the same 有权用于骨植入的无定形磷酸钙/硫酸钙半水合物复合物（CSH / ACP）及其制备方法公开(公告)号：US09056097B2
公开(公告)日：2015-06-16
申请号：US13010473
申请日：2011-01-20
Applicant: Jen-Chang Yang , Sheng-Yang Lee , Duen-Cheng Wang , Haw-Ming Huang , Wei-Jen Chang , Malosi Poma , Hong-Da Wu , Dian-Yu Ji
Inventor： Jen-Chang Yang , Sheng-Yang Lee , Duen-Cheng Wang , Haw-Ming Huang , Wei-Jen Chang , Malosi Poma , Hong-Da Wu , Dian-Yu Ji
CPC classification number: A61K33/42 , A61L27/425 , A61L27/427
Abstract: The invention provides a composite of α-calcium sulfate (CS) hemihydrate/amorphous calcium phosphate (α-CSH/ACP), comprising α-CSH and ACP at a weight ratio of about 10:90 to about 90:10. Particularly, the composite of the invention has a resorption period of 3-6 months. The invention also provides a one-pot process for producing α-CSH/ACP composite of the invention. The one-pot process of the invention can produce α-CSH and ACP in a single process and easily obtain α-CSH/ACP composite.
Abstract translation: 本发明提供了以约10:90至约90:10的重量比包含α-CSH和ACP的α-硫酸钙（CS）半水合物/无定形磷酸钙（α-CSH / ACP）的复合物。 特别地，本发明的复合材料的吸收期为3-6个月。 本发明还提供了一种用于制备本发明的α-CSH / ACP复合材料的一锅法。 本发明的一锅法可以在单一工艺中生产α-CSH和ACP，容易获得α-CSH / ACP复合材料。
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15.发明授权Calcium phosphate complex for oral care applications, its preparation method, and compositions containing the same 有权用于口腔护理应用的磷酸钙复合物，其制备方法和含有它们的组合物公开(公告)号：US08263048B2
公开(公告)日：2012-09-11
申请号：US12975052
申请日：2010-12-21
Applicant: Jen-Chang Yang , Sheng-Yang Lee , Der-Zen Liu , Nai-Chia Teng , En-Sheng Ke , Chien Chung Chen , Dian-Yu Ji , Chen-Feng Ma , Hong-Da Wu
Inventor： Jen-Chang Yang , Sheng-Yang Lee , Der-Zen Liu , Nai-Chia Teng , En-Sheng Ke , Chien Chung Chen , Dian-Yu Ji , Chen-Feng Ma , Hong-Da Wu
CPC classification number: A61Q11/00 , A61K8/24 , A61K8/88 , A61K2800/58
Abstract: The invention is directed to a calcium phosphate complex and the composition containing the same for oral care applications, in which the calcium phosphate complex is formed by chelating the γ-polyglutamic acid (γ-PGA) with amorphous calcium phosphate (ACP). This complex can prevent crystallization of ACP and maintain its high solubility. The calcium phosphate complex has superior mucoadhesion properties, allowing it to remain in the mouth longer and offering effective buffering, by which dental caries can be alleviated and prevented.
Abstract translation: 本发明涉及一种磷酸钙复合物和含有该磷酸钙络合物的组合物，其中通过用无定形磷酸钙（ACP）螯合γ-聚谷氨酸（γ-PGA）形成磷酸钙复合物。 该复合物可以防止ACP的结晶并保持其高溶解度。 磷酸钙复合物具有优异的粘膜粘附性质，使其能够更长时间地保留在口腔中，并提供有效的缓冲，可以减轻和预防龋齿。
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Patent Agency Ranking
16.发明申请公开(公告)号：US20110229547A1
公开(公告)日：2011-09-22
申请号：US12725163
申请日：2010-03-16
Applicant: Jen-Chang Yang , Sheng-Yang Lee , Tsuimin Tsai , Hong-Da Wu , Hsin-Tai Hu , Yan-Cheng Yang , Chen-Feng Ma
Inventor： Jen-Chang Yang , Sheng-Yang Lee , Tsuimin Tsai , Hong-Da Wu , Hsin-Tai Hu , Yan-Cheng Yang , Chen-Feng Ma
CPC classification number: A61K35/32 , A61K35/28 , A61K38/1875 , A61K38/39 , A61L27/10 , A61L27/12 , A61L27/18 , A61L27/20 , A61L27/56 , A61L2430/02 , C08L79/02
Abstract: The present invention relates to a process of using a heat responsive mixture to produce inorganic interconnected 3D open-cell bone substitutes which can be applied in the orthopedic or dental field for treatment of bone damage. The invention provides a simple and easily-controlled process of preparing porous inorganic bone substitute materials.
Abstract translation: 本发明涉及使用热响应混合物来生产可应用于整形外科或牙科领域用于治疗骨损伤的无机互连3D开放细胞骨替代物的方法。 本发明提供了制备多孔无机骨替代材料的简单且容易控制的方法。
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17.发明申请CALCIUM PHOSPHATE COMPLEX FOR ORAL CARE APPLICATIONS, ITS PREPARATION METHOD, AND COMPOSITIONS CONTAINING THE SAME 有权用于口腔护理应用的磷酸钙复合物，其制备方法和包含其的组合物公开(公告)号：US20110150791A1
公开(公告)日：2011-06-23
申请号：US12975052
申请日：2010-12-21
Applicant: JEN-CHANG YANG , SHENG-YANG LEE , DER-ZEN LIU , NAI-CHIA TENG , EN-SHENG KE , CHIEN CHUNG CHEN , DIAN-YU JI , CHEN-FENG MA , HONG-DA WU
Inventor： JEN-CHANG YANG , SHENG-YANG LEE , DER-ZEN LIU , NAI-CHIA TENG , EN-SHENG KE , CHIEN CHUNG CHEN , DIAN-YU JI , CHEN-FENG MA , HONG-DA WU
CPC classification number: A61Q11/00 , A61K8/24 , A61K8/88 , A61K2800/58
Abstract: The invention is directed to a calcium phosphate complex and the composition containing the same for oral care applications, in which the calcium phosphate complex is formed by chelating the γ-polyglutamic acid (γ-PGA) with amorphous calcium phosphate (ACP). This complex can prevent crystallization of ACP and maintain its high solubility. The calcium phosphate complex has superior mucoadhesion properties, allowing it to remain in the mouth longer and offering effective buffering, by which dental caries can be alleviated and prevented.
Abstract translation: 本发明涉及一种磷酸钙复合物和含有该磷酸钙络合物的组合物，其中通过用无定形磷酸钙（ACP）螯合γ-聚谷氨酸（γ-PGA）形成磷酸钙复合物。 该复合物可以防止ACP的结晶并保持其高溶解度。 磷酸钙复合物具有优异的粘膜粘附性质，使其能够更长时间地保留在口腔中，并提供有效的缓冲，可以减轻和预防龋齿。
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公开(公告)号：US20050287494A1
公开(公告)日：2005-12-29
申请号：US10946007
申请日：2004-09-22
Applicant: Jen-Chang Yang , Hsien-Kun Lee , Sheng-Yang Lee , Ching-Wu Weng , Jiunn-Liang Chen , Lin Hsu-Ting
Inventor： Jen-Chang Yang , Hsien-Kun Lee , Sheng-Yang Lee , Ching-Wu Weng , Jiunn-Liang Chen , Lin Hsu-Ting
IPC: A61C5/14 , A61C9/00 , A61K6/00 , A61K31/717 , A61K33/12
CPC classification number: A61K31/717 , A61C9/0033 , A61K6/0011 , A61K6/0058 , A61K33/12 , A61K2300/00 , C08L1/02 , C08L33/18 , C08L77/10
Abstract: A gingival retraction material is prepared using fibrillated fibers to improve viscosity and combining taste-modifying agent, color agent, and kaolin filler to form a paste-like structure having the viscosity ranging from 31.0×106 cP to 71.0×106 cP. The gingival material is injectable into the patient's gingival sulcus to provide a physical active force that widens the patient's gingival sulcus by means of the material viscosity and also to control gingival tissue fluid and hemostasis so as to keep the gingival sulcus dry for further mold impressions.
Abstract translation: 使用原纤化纤维制备牙龈回缩材料以改善粘度，并结合调味剂，着色剂和高岭土填料形成粘度范围为31.0×10 -6 c至71.0的糊状结构 c 10。 牙龈材料可注射到患者的牙龈沟中，以提供物理活性力，通过材料粘度扩大患者的牙龈沟，并且还控制牙龈组织液和止血，以保持牙龈干燥以获得更多的模具印模。
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19.发明授权公开(公告)号：US08465582B2
公开(公告)日：2013-06-18
申请号：US12725163
申请日：2010-03-16
Applicant: Jen-Chang Yang , Sheng-Yang Lee , Tsuimin Tsai , Hong-Da Wu , Hsin-Tai Hu , Yan-Cheng Yang , Chen-Feng Ma
Inventor： Jen-Chang Yang , Sheng-Yang Lee , Tsuimin Tsai , Hong-Da Wu , Hsin-Tai Hu , Yan-Cheng Yang , Chen-Feng Ma
IPC: A61L27/00
CPC classification number: A61K35/32 , A61K35/28 , A61K38/1875 , A61K38/39 , A61L27/10 , A61L27/12 , A61L27/18 , A61L27/20 , A61L27/56 , A61L2430/02 , C08L79/02
Abstract: The present invention relates to a process of using a heat responsive mixture to produce inorganic interconnected 3D open-cell bone substitutes which can be applied in the orthopedic or dental field for treatment of bone damage. The invention provides a simple and easily-controlled process of preparing porous inorganic bone substitute materials.
Abstract translation: 本发明涉及使用热响应混合物来生产可应用于整形外科或牙科领域用于治疗骨损伤的无机互连3D开放细胞骨替代物的方法。 本发明提供了制备多孔无机骨替代材料的简单且容易控制的方法。
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公开(公告)号：US20120136441A1
公开(公告)日：2012-05-31
申请号：US12956485
申请日：2010-11-30
Applicant: WEI-CHUNG YANG , JEN-CHANG YANG , DUEN-JENG WANG , SHENG-YANG LEE , YAN-CHIH CHEN
Inventor： WEI-CHUNG YANG , JEN-CHANG YANG , DUEN-JENG WANG , SHENG-YANG LEE , YAN-CHIH CHEN
CPC classification number: A61L27/56 , A61F2/4455 , A61F2002/30011 , A61F2002/30062 , A61L27/446 , A61L2430/02
Abstract: The invention relates to a method of preparing a composite or porous composite used as a biodegradable scaffold, the composite prepared therefrom and the use of the composite. In particular, the composite is a calcium sulfate-polylactic acid composite or porous composite and the composite can be especially used as an in situ pore forming scaffold.
Abstract translation: 本发明涉及一种制备用作生物可降解支架的复合或多孔复合材料的方法，由其制备的复合材料和复合材料的用途。 特别地，复合材料是硫酸钙 - 聚乳酸复合材料或多孔复合材料，并且该复合材料可以特别用作原位成孔支架。
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