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公开(公告)号：US20150292995A1
公开(公告)日：2015-10-15
申请号：US14747837
申请日：2015-06-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Kurt J. Halverson , Raj Rajagopal
IPC: G01N1/40
CPC classification number: G01N1/4077 , C12M47/04 , C12Q1/24 , G01N1/405 , G01N33/1866 , G01N2001/4088
Abstract: Kits and systems for isolating microorganisms from a sample, the sample including sample matrix and microorganisms, the kit including concentration agent; and a system for isolating microorganisms from a sample.
Abstract translation: 用于从样品中分离微生物的试剂盒和系统，样品包括样品基质和微生物，试剂盒包括浓缩剂; 以及用于从样品中分离微生物的系统。
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公开(公告)号：US20150132740A1
公开(公告)日：2015-05-14
申请号：US14400390
申请日：2013-05-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Evan Koon Lun Yuuji Hajime , Andrew W. Rabins
IPC: G01N33/53 , G01N33/569
CPC classification number: G01N33/5306 , B01J20/0277 , B01J20/28026 , B01J20/28028 , C12N11/14 , C12Q1/04 , C12Q1/24 , G01N33/56916 , G01N33/56938 , G01N33/56961 , G01N2333/245 , G01N2333/395
Abstract: A concentration agent for microorganisms is provided that contains both lanthanum and carbonate. Additionally, articles that include the concentration agent and methods of concentrating a microorganism using the concentration agent are provided.
Abstract translation: 提供含有镧和碳酸盐的微生物浓缩剂。 此外，提供了包含浓缩剂的物质和使用浓缩剂浓缩微生物的方法。
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公开(公告)号：US20140011253A1
公开(公告)日：2014-01-09
申请号：US14023782
申请日：2013-09-11
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Tushar A. Kshirsagar , Thomas E. Wood
IPC: C12N11/14
CPC classification number: C12N11/14 , B01J20/02 , B01J20/06 , B01J20/14 , B01J20/3204 , B01J20/3234 , B01J20/3236 , C12N1/02 , C12Q1/04 , C12Q1/24
Abstract: A concentration agent for capture of microorganisms, including diatomaceous earth bearing, on at least a portion of its surface, a surface treatment comprising a surface modifier comprising titanium dioxide, fine-nanoscale gold or platinum, or a combination thereof, and methods for making the concentration agent.
Abstract translation: 用于在其表面的至少一部分上捕获包括硅藻土轴承的微生物的浓缩剂，包括包含二氧化钛，细纳米金或铂或其组合的表面改性剂的表面处理，以及用于制备 浓缩剂。
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公开(公告)号：US10709807B2
公开(公告)日：2020-07-14
申请号：US15509501
申请日：2015-09-28
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar
Abstract: Porous devices are provided that include a particle-containing fibrous porous matrix and a fluid absorbed in the particle-containing porous fibrous nonwoven matrix. The particle-containing fibrous porous matrix includes a porous fibrous nonwoven matrix containing first polyolefin fibers, second polyolefin fibers including poly(ethylene), and fiberglass fibers; and microorganism-binding particles. The microorganism-binding particles are enmeshed in said porous fibrous nonwoven matrix. Methods of debridement are provided including providing a porous device including a particle-containing fibrous porous matrix and wiping a wound or an area of skin with the device; and providing a porous device including a porous fibrous nonwoven matrix and wiping a wound with the device. Further, kits are provided including a sterile package containing at least one porous device, and typically also instructions for debridement.
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公开(公告)号：US10240018B2
公开(公告)日：2019-03-26
申请号：US14602603
申请日：2015-01-22
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Andrew W. Rabins
Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising a sintered porous polymer matrix comprising at least one concentration agent that comprises an amorphous metal silicate and that has a surface composition having a metal atom to silicon atom ratio of less than or equal to 0.5, as determined by X-ray photoelectron spectroscopy (XPS); (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration device with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration device.
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Patent Agency Ranking
公开(公告)号：US20180128722A1
公开(公告)日：2018-05-10
申请号：US15849830
申请日：2017-12-21
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Andrew W. Rabins
Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising (1) a porous fibrous nonwoven matrix and (2) a plurality of particles of at least one concentration agent that comprises a metal silicate, the particles being enmeshed in the porous fibrous nonwoven matrix; (b) providing a sample comprising at least one target cellular analyte; (c) contacting the concentration device with the sample such that at least a portion of the at least one target cellular analyte is bound to or captured by the concentration device; and (d) detecting the presence of at least one bound target cellular analyte.
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公开(公告)号：US09719125B2
公开(公告)日：2017-08-01
申请号：US15091024
申请日：2016-04-05
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Kurt J. Halverson , Neil Percy , James E. Aysta
Abstract: The present disclosure describes methods for concentrating microorganisms with concentration agents in a sampling device and the sampling device described herein. More specifically, methods for concentrating microorganisms from large volume samples with concentration agents in a sampling device can provide for rapid, low cost, simple (involving no complex equipment or procedures), and/or effective processes under a variety of conditions.
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公开(公告)号：US09382570B2
公开(公告)日：2016-07-05
申请号：US14069416
申请日：2013-11-01
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Raj Rajagopal , Kurt J. Halverson , Manjiri T. Kshirsagar , James E. Aysta
IPC: C12M1/34 , C12M3/00 , C12M1/00 , C12Q1/68 , G01N15/06 , G01N33/00 , G01N33/48 , C12Q1/04 , B01L3/00 , C12M1/24 , C12M1/30 , G01N33/569 , A61B10/00 , A61B10/02
CPC classification number: C12Q1/04 , A61B10/0045 , A61B10/02 , B01L3/5082 , B01L2200/026 , B01L2200/10 , C12M23/08 , C12M23/32 , C12M23/34 , C12M33/02 , G01N33/56916 , G01N2333/245
Abstract: The present invention provides methods to concentrate cells onto microparticles, to concentrate the microparticles, and to detect the cells. The present invention also includes unitary sample preparation and detection devices to be used in accordance with the methods.
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19.发明申请MAGNETIC SEPARATION PROCESS USING CARBOXYL-FUNCTIONALIZED SUPERPARAMAGNETIC NANOCLUSTERS 审中-公开使用羧基官能化超级纳米粒子的磁分离方法公开(公告)号：US20160122797A1
公开(公告)日：2016-05-05
申请号：US14895993
申请日：2014-06-05
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Lijun Zu
CPC classification number: C12Q1/10 , C12Q1/04 , G01N15/0612 , G01N15/1463 , G01N35/0098 , G01N2015/0088
Abstract: A process including: contacting a plurality of carboxyl-functionalized superparamagnetic nanoclusters with a liquid sample potentially comprising at least one microorganism strain; magnetically separating at least some of the carboxyl-functionalized superparamagnetic nanoclusters from at least a portion of the liquid sample; and, assaying the magnetically-separated superparamagnetic nanoclusters for evidence of the at least one microorganism strain having been non-specifically bound thereto.
Abstract translation: 一种方法，包括：使多个羧基官能化的超顺磁性纳米团簇与潜在地包含至少一种微生物菌株的液体样品接触; 从液体样品的至少一部分磁性分离至少一些羧基官能化的超顺磁性纳米簇; 以及测定磁分离的超顺磁性纳米簇，以证明至少一种非特异性结合于其上的微生物菌株。
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公开(公告)号：US20150133574A1
公开(公告)日：2015-05-14
申请号：US14602603
申请日：2015-01-22
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Andrew W. Rabins
IPC: C08J9/00
CPC classification number: C08J9/0066 , B01D61/147 , B01D63/00 , C08J9/0061 , C08J2323/06 , C08J2423/06 , C12Q1/24
Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising a sintered porous polymer matrix comprising at least one concentration agent that comprises an amorphous metal silicate and that has a surface composition having a metal atom to silicon atom ratio of less than or equal to 0.5, as determined by X-ray photoelectron spectroscopy (XPS); (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration device with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration device.
Abstract translation: 用于捕获或浓缩用于检测或测定的微生物的方法包括（a）提供包含烧结的多孔聚合物基质的浓缩装置，所述多孔聚合物基质包含至少一种浓缩剂，所述浓缩剂包含无定形金属硅酸盐，并且具有具有金属原子与硅原子的表面组成 比例小于或等于0.5，如通过X射线光电子能谱（XPS）测定的; （b）提供包含至少一种微生物菌株的样品; 和（c）使浓缩装置与样品接触，使得至少一部分微生物菌株与浓缩装置结合或捕获。
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