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公开(公告)号：US20240366490A1
公开(公告)日：2024-11-07
申请号：US18543854
申请日：2023-12-18
Applicant: Allergan, Inc.
Inventor： Elizabeta Pavlovic , Monica A. Serban , Xiaojie Yu , Nicholas J. Manesis
IPC: A61K8/64 , A61K8/73 , A61L27/20 , A61L27/22 , A61L27/36 , A61L27/52 , A61Q19/08 , C08B37/08 , C08H1/00 , C08J3/075 , C08J3/24 , C08L5/08 , C08L89/00
Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.
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公开(公告)号：US20220023186A1
公开(公告)日：2022-01-27
申请号：US17396597
申请日：2021-08-06
Applicant: Allergan, Inc.
Inventor： Gabriel N. Njikang , Xiaojie Yu , Futian Liu , Nicholas J. Manesis
Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions made with a di-amine or multiamine crosslinker in the presence of a carbodiimide coupling agent.
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13.发明申请公开(公告)号：US20200000968A1
公开(公告)日：2020-01-02
申请号：US16527804
申请日：2019-07-31
Applicant: Allergan, Inc.
Inventor： Jacob F. Pollock , Lauren E. Kokai , Cunqi Cui , Xiaojie Yu , Dennis E. Van Epps , Darin J. Messina
IPC: A61L27/52 , A61L27/24 , A61K8/73 , A61Q19/08 , A61K8/04 , A61L27/26 , A61L27/36 , A61L27/38 , A61L27/20 , A61L27/54 , A61L27/58
Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
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公开(公告)号：US10434214B2
公开(公告)日：2019-10-08
申请号：US15727916
申请日：2017-10-09
Applicant: Allergan, Inc.
Inventor： Xiaojie Yu , Nicholas J. Manesis , Jacob Pollock
Abstract: Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers. The macromolecular matrix may include a crosslinked combination of hyaluronic acid and collagen.
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公开(公告)号：US10300169B2
公开(公告)日：2019-05-28
申请号：US15686036
申请日：2017-08-24
Applicant: Allergan, Inc.
Inventor： Xiaojie Yu , Darin J. Messina , Elizabeta Pavlovic , Cunqi Cui , Kate M. Smither
Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
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Patent Agency Ranking
16.发明申请公开(公告)号：US20170348463A1
公开(公告)日：2017-12-07
申请号：US15686444
申请日：2017-08-25
Applicant: Allergan, Inc.
Inventor： Jacob F. Pollock , Lauren E. Kokai , Cunqi Cui , Xiaojie Yu , Dennis E. Van Epps , Darin J. Messina
CPC classification number: A61L27/52 , A61K8/042 , A61K8/735 , A61K2800/91 , A61L27/20 , A61L27/24 , A61L27/26 , A61L27/3604 , A61L27/3804 , A61L27/54 , A61L27/58 , A61L2300/412 , A61L2300/64 , A61L2400/06 , A61L2430/34 , A61Q19/08 , C08L89/06 , C08L5/08
Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
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公开(公告)号：US09795711B2
公开(公告)日：2017-10-24
申请号：US15609967
申请日：2017-05-31
Applicant: Allergan, Inc.
Inventor： Xiaojie Yu , Nicholas J. Manesis , Jacob Pollock
CPC classification number: A61L27/24 , A61K8/042 , A61K8/735 , A61K2800/91 , A61L27/26 , A61L27/3695 , A61L27/52 , A61L2400/06 , A61L2430/34 , A61Q19/08 , C08L5/08 , C08L89/06
Abstract: Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers. The macromolecular matrix may include a crosslinked combination of hyaluronic acid and collagen.
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18.发明授权公开(公告)号：US09782517B2
公开(公告)日：2017-10-10
申请号：US15494991
申请日：2017-04-24
Applicant: Allergan, Inc.
Inventor： Jacob F. Pollock , Lauren E. Kokai , Cunqi Cui , Xiaojie Yu , Dennis E. Van Epps , Darin J. Messina
CPC classification number: A61L27/52 , A61K8/042 , A61K8/735 , A61K2800/91 , A61L27/20 , A61L27/24 , A61L27/26 , A61L27/3604 , A61L27/3804 , A61L27/54 , A61L27/58 , A61L2300/412 , A61L2300/64 , A61L2400/06 , A61L2430/34 , A61Q19/08 , C08L89/06 , C08L5/08
Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
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公开(公告)号：US20140315828A1
公开(公告)日：2014-10-23
申请号：US13868010
申请日：2013-04-22
Applicant: ALLERGAN, INC.
Inventor： Elizabeta Pavlovic , Monica A. Serban , Xiaojie Yu , Nicholas J. Manesis
Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.
Abstract translation: 可用作真皮填料的组合物和使用这种组合物治疗各种皮肤和软组织病症的方法。 真皮填料可以包括使用例如两个交联剂连接到透明质酸的丝，并且可以用于治疗面部缺陷，面部缺陷，面部增大，乳房缺陷，隆胸或乳房重建。
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公开(公告)号：US20140011980A1
公开(公告)日：2014-01-09
申请号：US13934976
申请日：2013-07-03
Applicant: Allergan, Inc.
Inventor： Kaustubh S. Chitre , Xiaojie Yu , Nicholas J. Manesis
IPC: A61L2/08
CPC classification number: A61L2/08 , A61L2/084 , A61L2/085 , A61L2/10 , A61L27/20 , A61L27/24 , A61L27/3604 , A61L27/52
Abstract: Method for sterilizing a hydrogel composition include subjecting the composition to pulsed light comprising broadband spectrum radiation, the pulsed light being at a dose effective to sterilize the composition without causing significant change in rheology of the composition.
Abstract translation: 用于对水凝胶组合物进行灭菌的方法包括使组合物经受包含宽带光谱辐射的脉冲光，脉冲光以有效消毒组合物的剂量而不引起组合物流变学的显着变化。
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