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35 条记录 (耗时 0.025 秒)

    Strain gauge
    11.
    发明申请
    Strain gauge 失效
    应变计

    公开(公告)号：US20070186664A1

    公开(公告)日：2007-08-16

    申请号：US10581355

    申请日：2004-12-01

    申请人： Ian Powlesland ,  Alan Wilson

    发明人： Ian Powlesland ,  Alan Wilson

    IPC分类号： G01B7/16

    CPC分类号： G01B7/18 ,  G01L1/18

    摘要： A strain gauge (10), comprising a silicon strain sensing element (14) for sensing strain with first and second load points (16) and provided with a pair of piezo-resistors (22) located between said load points such that, when said strain sensing element (14) is subjected to tension or compression at said load points, a first of said pair of piezo-resistors (22a,22b) is subjected to compression and a second of said pair of piezo-resistors (22a,22b) is subjected to tension, wherein a change in relative resistance of said pair of piezo-resistors is induced by subjecting said strain sensing element to compression or tension.

    摘要翻译： 一种应变仪（10），包括用于感测具有第一和第二负载点（16）的应变的硅应变传感元件（14），并且设置有位于所述负载点之间的一对压电阻器（22），使得当所述 应变感测元件（14）在所述负载点处受到张力或压缩，所述一对压电电阻器（22a，22b）中的第一个被压缩，并且所述一对压电电阻器（22a）中的第二个 ，22b）受到张力，其中所述一对压电阻器的相对电阻的变化是通过使所述应变传感元件经受压缩或张力而引起的。

    Micro-electronic bond degradation sensor and method of manufacture
    12.
    发明授权
    Micro-electronic bond degradation sensor and method of manufacture 失效
    微电子键降解传感器及其制造方法

    公开(公告)号：US06693417B2

    公开(公告)日：2004-02-17

    申请号：US10139035

    申请日：2002-05-03

    申请人： Alan Wilson

    发明人： Alan Wilson

    IPC分类号： G01R100

    CPC分类号： G01N17/02 ,  G01N33/442

    摘要： A micro-electronic bond degradation sensor includes a sensor substrate having sensor circuitry and a sensor stud and a power stud extending therefrom. The sensor circuitry includes a voltage-to-current amplifier having an input coupled to sensor stud and an output coupled to the power stud. The voltage-to-current amplifier is operable to convert a voltage signal occurring along the sensor stud to a current signal output along the power stud.

    摘要翻译： 微电子键降解传感器包括具有传感器电路和传感器螺柱的传感器基板和从其延伸的电源螺柱。 传感器电路包括电压 - 电流放大器，其具有耦合到传感器螺柱的输入和耦合到电源螺柱的输出。 电压 - 电流放大器可操作以将沿着传感器螺柱发生的电压信号转换成沿着电力螺柱输出的电流信号。

    SYSTEM AND METHOD FOR SERUM BASED CANCER DETECTION
    13.
    发明申请
    SYSTEM AND METHOD FOR SERUM BASED CANCER DETECTION 审中-公开
    基于血清的癌症检测系统及方法

    公开(公告)号：US20150294076A1

    公开(公告)日：2015-10-15

    申请号：US14440987

    申请日：2013-11-06

    申请人： Patrick TREADO ,  Shona STEWART ,  Heather KIRSCHNER ,  Ryan PRIORE ,  Alan WILSON ,  CHEMIMAGE CORPORATION

    发明人： Patrick Treado ,  Shona Stewart ,  Heather Kirschner ,  Ryan Priore ,  Alan Wilson

    IPC分类号： G06F19/00 ,  G06F19/24 ,  G01N21/65 ,  G01N33/49

    CPC分类号： G16H50/20 ,  G01J3/1804 ,  G01J3/44 ,  G01J3/4406 ,  G01N21/65 ,  G01N33/49 ,  G01N33/57419 ,  G16B40/00

    摘要： A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.

    摘要翻译： 用于分析诸如干人血清的生物样品以确定诸如结肠直肠癌（CRC）的疾病状态的系统和方法。 使用干燥的样品可能具有增强样品组分的局部浓度和/或分割的潜力。 该方法可以包括照射生物样品的至少一个位置以产生多个相互作用的光子，收集相互作用的光子并产生代表生物样品的至少一个拉曼数据集。 系统可以包括照明源以照亮生物样品的至少一个位置并且生成至少一个多个相互作用的光子，至少一个反射镜，用于将相互作用的光子引导到检测器。 检测器可以被配置为产生代表生物样品的至少一个拉曼数据集。 该系统和方法可以利用FAST设备进行多点分析，或者可以配置为使用线扫描配置分析样本。

    Environment monitoring and recording tag with remote sensing capability
    14.
    发明授权
    Environment monitoring and recording tag with remote sensing capability 有权
    具有遥感能力的环境监测和记录标签

    公开(公告)号：US09035773B2

    公开(公告)日：2015-05-19

    申请号：US12722958

    申请日：2010-03-12

    申请人： Michael Petersen ,  Alan Wilson ,  Dean Brotzel

    发明人： Michael Petersen ,  Alan Wilson ,  Dean Brotzel

    IPC分类号： G08B13/14 ,  G01D21/00 ,  G01D9/00 ,  G06K19/07

    CPC分类号： G01D21/00 ,  G01D9/005 ,  G06K19/0717

    摘要： A tag includes an integrated circuit thereon, including memory, antenna means for RF transmission of data acquired by the integrated circuit, a sensor sensing environmental conditions to which the sensor is subjected, the sensor providing signals based on the environmental conditions to the integrated circuit, a thermistor device of increasing the accuracy of the tag by confining on-board calculation data to a resistance domain and leaving conversion of the data to a temperature domain for an external device once the data is retrieved from the tag's memory.

    摘要翻译： 标签包括其上的集成电路，包括存储器，用于RF传输由集成电路获取的数据的天线装置，感测传感器经受的环境条件的传感器，传感器基于环境条件向集成电路提供信号， 一种热敏电阻器件，其通过将板上计算数据限制在电阻域上，并且一旦从标签的存储器检索到数据，就将数据转换为外部设备的温度域，从而提高了标签的精度。

    Process for Casting and Extracting Biomedical Devices
    15.
    发明申请
    Process for Casting and Extracting Biomedical Devices 审中-公开
    铸造和提取生物医学设备的工艺

    公开(公告)号：US20070138669A1

    公开(公告)日：2007-06-21

    申请号：US11611182

    申请日：2006-12-15

    申请人： Yu-Chin Lai ,  Edmond Quinn ,  Alan Wilson

    发明人： Yu-Chin Lai ,  Edmond Quinn ,  Alan Wilson

    IPC分类号： B29D11/00

    CPC分类号： G02B1/043 ,  B29D11/00125

    摘要： A process for producing polymeric biomedical devices, such as contact lenses, involves casting a monomeric mixture including a diluent; and subsequently removing extractables from the devices by contacting the devices with the an additional volume of the diluent.

    摘要翻译： 用于生产聚合物生物医学装置（例如隐形眼镜）的方法涉及浇铸包含稀释剂的单体混合物; 并随后通过使装置与额外体积的稀释剂接触从装置中除去可提取物。

    Carboxyalkyl cellulose esters for sustained delivery of pharmaceutically active substances
    16.
    发明申请
    Carboxyalkyl cellulose esters for sustained delivery of pharmaceutically active substances 审中-公开
    用于持续递送药物活性物质的羧甲基纤维素酯

    公开(公告)号：US20070104787A1

    公开(公告)日：2007-05-10

    申请号：US11592129

    申请日：2006-11-03

    申请人： Jessica Posey-Dowty ,  Thelma Watterson ,  Kevin Edgar ,  Shane Kirk ,  Michael Welty ,  Jinghua Yuan ,  Michael Shelton ,  Larry Lingerfelt ,  Alan Wilson

    发明人： Jessica Posey-Dowty ,  Thelma Watterson ,  Kevin Edgar ,  Shane Kirk ,  Michael Welty ,  Jinghua Yuan ,  Michael Shelton ,  Larry Lingerfelt ,  Alan Wilson

    IPC分类号： A61K31/717 ,  A61K9/22

    CPC分类号： A61K9/2054 ,  A61K9/10 ,  A61K9/2013 ,  A61K9/4808 ,  A61K31/717

    摘要： Disclosed herein are pharmaceutical compositions comprising carboxyalkylcellulose esters for sustained delivery of pharmaceutically active substances. The composition comprises: at least one pharmaceutically active agent, and at least one carboxyalkyl cellulose ester comprising an anhydroglucose repeat unit having the structure: wherein: R1-R6 are each independently selected from —OH, —OC(O)(alkyl), and —O(CH2)xC(O)OH, and pharmaceutically acceptable salts thereof, wherein x ranges from 1-3, a degree of substitution per anhydroglucose of —OH ranges from 0.1 to 0.7, a degree of substitution per anhydroglucose of —C(O)(alkyl) ranges from 0.1 to 2.7, and a degree of substitution per anhydroglucose of —O(CH2)xC(O)OH ranges from 0.2 to 0.75, and wherein in pharmaceutically acceptable media, the composition exhibits sustained release of the at least one pharmaceutically active agent. Also disclosed are methods of administering the compositions for sustained delivery, such as delivery following zero order kinetics.

    摘要翻译： 本文公开了包含用于持续递送药物活性物质的羧基烷基纤维素酯的药物组合物。 所述组合物包含：至少一种药物活性剂和至少一种羧基烷基纤维素酯，其包含具有以下结构的脱水葡萄糖重复单元：其中：R 1〜R 6各自为 独立地选自-OH，-OC（O）（烷基）和-O（CH 2）2 C（O）OH及其药学上可接受的盐，其中 x的范围为1-3，-OH的每个脱水葡萄糖的取代度为0.1至0.7，-C（O）（烷基）的每个脱水葡萄糖的取代度为0.1- 2.7，并且每个脱水葡萄糖的取代度 -O（CH 2）2 C（O）OH的范围为0.2至0.75，并且其中在药学上可接受的介质中，所述组合物表现出至少一种 药物活性剂。 还公开了施用用于持续递送的组合物的方法，例如在零级动力学之后的递送。

    Medicament dispenser
    18.
    发明申请
    Medicament dispenser 有权
    药剂分配器

    公开(公告)号：US20060196504A1

    公开(公告)日：2006-09-07

    申请号：US10565515

    申请日：2004-07-21

    申请人： Stephen Augustyn ,  Gary Crosby ,  Michael Davies ,  Stephen Harvey ,  Mark Palmer ,  Paul Rand ,  Alan Wilson

    发明人： Stephen Augustyn ,  Gary Crosby ,  Michael Davies ,  Stephen Harvey ,  Mark Palmer ,  Paul Rand ,  Alan Wilson

    IPC分类号： A61M15/00 ,  B65D83/06

    CPC分类号： A61M15/0045 ,  A61M15/0003 ,  A61M15/0025 ,  A61M15/0043 ,  A61M15/0051 ,  A61M15/0055 ,  A61M15/0078 ,  A61M15/008 ,  A61M15/0083 ,  A61M2202/064

    摘要： There is provided a medicament dispenser for containing plural elongate form medicament carriers, each having multiple distinct medicament dose portions carried thereby, the dispenser having a housing of generally non-circular form, and within said housing a dispensing mechanism for dispensing the distinct medicament dose portions carried by each of said plural medicament carriers. The mechanism comprises at least one receiving station for receiving each of the plural medicament carriers; a release for releasing in combination a distinct medicament dose portion from each of the plural medicament carriers on receipt thereof by said receiving station; an outlet, positioned to be in communication with the distinct medicament dose portions releasable by said release; and at least one indexer for individually indexing the distinct medicament dose portions of each of the plural medicament carriers. The dispenser contains plural elongate form medicament carriers, each having multiple distinct dose portions carried thereby. At least one of said medicament carriers has the form of a continuous loop.

    摘要翻译： 提供了一种用于容纳多个细长形状的药物载体的药物分配器，每个细长形式的药物载体具有由其承载的多个不同的药物剂量部分，分配器具有大致非圆形形状的壳体，并且在所述壳体内部具有用于分配不同药物剂量部分 由所述多个药物载体中的每一个承载。 该机构包括用于接收多个药物载体中的每一个的至少一个接收站; 用于由所述接收站接收多个药物载体中的每一个的组合释放不同药物剂量部分的释放物; 出口，定位成与通过所述释放可释放的不同药物剂量部分连通; 以及至少一个索引器，用于单独索引多个药物载体中的每一个的不同药物剂量部分。 分配器包含多个细长形式的药物载体，每个具有多个不同的剂量部分。 所述药物载体中的至少一个具有连续环的形式。