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    IMPLANTS AND METHODS FOR MANUFACTURING SAME
    13.
    发明申请
    IMPLANTS AND METHODS FOR MANUFACTURING SAME 有权

    公开(公告)号：US20130302511A1

    公开(公告)日：2013-11-14

    申请号：US13942104

    申请日：2013-07-15

    Applicant: Allergan, Inc.

    Inventor： Alexei Goraltchouk ,  Dennis Van Epps ,  Thomas E. Powell

    IPC: A61F2/12

    CPC classification number: B05D3/107 ,  A61F2/12 ,  A61L27/30 ,  A61L27/56 ,  A61L2400/18

    Abstract: Implantable prosthesis, components of prosthesis, and methods of making same are provided. The methods generally include the steps of providing an implant shell, applying a curable fluid composition to the shell to form a coating thereon and applying a particulate component to the composition. The composition is a mixture, for example, an emulsion, containing a silicone-based elastomer dispersion and droplets of a suspended leachable agent. After the elastomer is stabilized and cured, the particulate component and leachable agent are removed, resulting in an implantable member having a porous, open-cell surface texture designed to be effective in reducing incidence of capsular formation or contraction.

    Implants and methods for manufacturing same
    16.
    发明授权
    Implants and methods for manufacturing same 有权
    植入物及其制造方法

    公开(公告)号：US08951596B2

    公开(公告)日：2015-02-10

    申请号：US13942104

    申请日：2013-07-15

    Applicant: Allergan, Inc.

    Inventor： Alexei Goraltchouk ,  Dennis Van Epps ,  Thomas E. Powell

    IPC: A61F2/52 ,  B05D3/10 ,  B05D3/02 ,  B05D1/38 ,  A61F2/12 ,  A61L27/30 ,  A61L27/56

    CPC classification number: B05D3/107 ,  A61F2/12 ,  A61L27/30 ,  A61L27/56 ,  A61L2400/18

    Abstract: Implantable prosthesis, components of prosthesis, and methods of making same are provided. The methods generally include the steps of providing an implant shell, applying a curable fluid composition to the shell to form a coating thereon and applying a particulate component to the composition. The composition is a mixture, for example, an emulsion, containing a silicone-based elastomer dispersion and droplets of a suspended leachable agent. After the elastomer is stabilized and cured, the particulate component and leachable agent are removed, resulting in an implantable member having a porous, open-cell surface texture designed to be effective in reducing incidence of capsular formation or contraction.

    Abstract translation: 提供可植入假体，假体的组成部分及其制造方法。 所述方法通常包括提供植入物外壳，将可固化流体组合物施加到外壳上以在其上形成涂层的步骤，并将颗粒组分施用于组合物。 组合物是混合物，例如含有硅氧烷基弹性体分散体和悬浮的可浸出试剂的液滴的乳液。 在弹性体稳定和固化之后，除去颗粒组分和可浸出的试剂，得到可植入的构件，其具有设计成有效减少荚膜形成或收缩的发生率的多孔，开放细胞表面织构。

    IMPLANTABLE MATERIALS
    17.
    发明申请
    IMPLANTABLE MATERIALS 审中-公开
    可植入材料

    公开(公告)号：US20140242258A1

    公开(公告)日：2014-08-28

    申请号：US14271292

    申请日：2014-05-06

    Applicant: Allergan, Inc.

    Inventor： Alexei Goraltchouk ,  Jordan Thompson ,  Miram M. Abiad ,  Kevin A. Ma

    IPC: A61L27/00

    CPC classification number: A61L27/00 ,  A61F2/12 ,  A61L27/18 ,  A61L27/56 ,  A61L2430/04 ,  C08L83/04

    Abstract: A textured breast implant is provided which generally includes a fluid fillable elastomeric shell having a texture defined by struts, for example, hollow struts, defining interconnected open cells. Methods of making the texture include applying a silicone dispersion to a base material and removing the base material from the coating to form a silicone-based structure comprising struts defining interconnected open cells, said struts including internal surfaces defining cavities within the struts. The method may further include the step of contacting the silicone based structure having cavities with a silicone dispersion to cause the silicone to enter and fill the cavities.

    Abstract translation: 提供纹理化的乳房植入物，其通常包括具有由支柱（例如，定义互连的开放细胞）的中空支柱限定的纹理的流体可填充的弹性体外壳。 制造纹理的方法包括将硅氧烷分散体施加到基材上并从涂层中除去基材以形成包含限定互连的开放电池的支柱的硅氧烷基结构，所述支柱包括限定支柱内的空腔的内表面。 该方法还可以包括使具有空腔的硅氧烷基结构与硅氧烷分散体接触以使硅酮进入和填充空腔的步骤。

    INTRAGASTRIC BALLOON SHELL MATERIALS AND CONSTRUCTION
    18.
    发明申请
    INTRAGASTRIC BALLOON SHELL MATERIALS AND CONSTRUCTION 审中-公开
    内部气囊材料和结构

    公开(公告)号：US20140066968A1

    公开(公告)日：2014-03-06

    申请号：US14075698

    申请日：2013-11-08

    Applicant: Allergan, Inc.

    Inventor： Elizabeta Pavlovic ,  Jordan Thompson ,  Loantrang Dang ,  Alexei Goraltchouk

    IPC: A61F5/00

    CPC classification number: A61F5/003 ,  A61F5/0036 ,  A61L31/042 ,  A61L31/048 ,  A61L31/06 ,  A61L31/14 ,  C08L79/02 ,  C08L67/04 ,  C08L1/28 ,  C08L5/08 ,  C08L23/16

    Abstract: An intragastric balloon with a 12-month lifespan. The intragastric balloon has a shell made of a material with as good as or better than initial mechanical properties of previous materials; i.e. higher ultimate tensile strength (UTS) and elongation at break (Eb), lower stiffness (K), higher acid stability, and improved resistance to infection. The new materials in particular provide improved acid resistance. These new materials produce a device that has reduced adverse events and a longer lifespan in vivo. The materials may form the entire wall of the shell or may form just a barrier layer coupled with a scaffold layer of a different material.

    Abstract translation: 一个12个月的寿命的胃内气球。 胃内球囊具有由先前材料的初始机械性能好或优于原材料的材料制成的外壳; 即更高的极限拉伸强度（UTS）和断裂伸长率（Eb），较低的刚度（K），较高的酸稳定性和改善的抗感染性。 新材料特别提供改善的耐酸性。 这些新材料产生的体内减少不良事件和更长使用寿命的装置。 材料可以形成壳的整个壁，或者可以形成仅与不同材料的支架层结合的阻挡层。

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