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公开(公告)号：US10980869B2
公开(公告)日：2021-04-20
申请号：US15703685
申请日：2017-09-13
Applicant: BAYLOR RESEARCH INSTITUTE
Inventor： Gerard Zurawski , Jacques F. Banchereau , Anne-Laure Flamar , Peter Klucar , Keiko Akagawa , Sandra Zurawski , SangKon Oh
IPC: A61K39/00 , A61K39/395 , C07K16/28 , C07K14/435
Abstract: The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccines and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.
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12.发明申请AGENTS THAT ENGAGE ANTIGEN-PRESENTING CELLS THROUGH DENDRITIC CELL ASIALOGLYCOPROTEIN RECEPTOR (DC-ASGPR) 审中-公开通过DENDRITIC CELL ASIALOGLYCOPROTEIN受体（DC-ASGPR）引入抗原呈递细胞的试剂公开(公告)号：US20160375126A1
公开(公告)日：2016-12-29
申请号：US15265236
申请日：2016-09-14
Applicant: BAYLOR RESEARCH INSTITUTE
Inventor： SangKon Oh , Dapeng Li
IPC: A61K39/145 , C12N7/00 , C12N5/0784 , C07K16/28
CPC classification number: A61K39/145 , A61K47/6849 , A61K51/1027 , A61K2039/5154 , C07K14/005 , C07K14/195 , C07K14/37 , C07K14/405 , C07K14/435 , C07K16/28 , C07K2317/24 , C07K2317/33 , C07K2317/56 , C07K2317/74 , C07K2317/75 , C07K2317/92 , C12N5/0639 , C12N7/00 , C12N2760/16122 , C12N2760/16134
Abstract: The present invention includes compositions and methods for making and using anti DC-ASGPR antibodies that can, e.g., activate DCs and other cells.
Abstract translation: 本发明包括用于制备和使用可以例如激活DC和其他细胞的抗DC-ASGPR抗体的组合物和方法。
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13.发明申请DENDRITIC CELL ASGPR TARGETING IMMUNOTHERAPEUTICS FOR MULTIPLE SCLEROSIS 审中-公开多发性硬化症多发性神经细胞ASGPR靶向性免疫抑制剂公开(公告)号：US20160296609A1
公开(公告)日：2016-10-13
申请号：US14901617
申请日：2014-06-27
Applicant: Baylor Research Institute
Inventor： SangKon Oh , Gerard Zurawski
CPC classification number: A61K39/0008 , A61K2039/505 , A61K2039/577 , C07K14/46 , C07K16/28 , C07K2319/33
Abstract: Methods and compositions for treating multiple sclerosis using dendritic cell anti-ASGPR antibodies fused to myelin basic protein or myelin oligodendrocyte glycoprotein provided.
Abstract translation: 使用与髓磷脂碱性蛋白或髓鞘少突胶质细胞糖蛋白融合的树突状细胞抗ASGPR抗体治疗多发性硬化症的方法和组合物。
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公开(公告)号：US20160022792A1
公开(公告)日：2016-01-28
申请号：US14819909
申请日：2015-08-06
Applicant: Baylor Research Institute
Inventor： Gerard Zurawski , Jacques F. Banchereau , Anne-Laure Flamar , Peter Klucar , Keiko Akagawa , Sandra Zurawski , SangKon Oh
IPC: A61K39/00 , C07K14/435 , C07K16/28
CPC classification number: A61K39/0011 , A61K2039/6056 , C07K14/435 , C07K16/2878 , C07K2319/00 , C07K2319/33 , C07K2319/91 , Y02A50/39 , Y02A50/466
Abstract: The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccines and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.
Abstract translation: 本发明包括用于表达，分泌和使用用作例如疫苗和抗原递送载体的用于将抗原递送至抗原呈递细胞的组合物和方法。 在一个实施方案中，载体是抗CD40抗体或其片段，以及与抗-CD40抗体或其片段（包括人源化抗体）连接的一个或多个抗原肽。
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公开(公告)号：US11267895B2
公开(公告)日：2022-03-08
申请号：US16946302
申请日：2020-06-15
Applicant: BAYLOR RESEARCH INSTITUTE
Inventor： Jacques F. Banchereau , Gerard Zurawski , Sandra Zurawski , SangKon Oh
IPC: C07K16/28 , C07K14/005 , A61K39/00
Abstract: The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccine and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.
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Patent Agency Ranking
16.发明授权公开(公告)号：US11173202B2
公开(公告)日：2021-11-16
申请号：US16372832
申请日：2019-04-02
Applicant: BAYLOR RESEARCH INSTITUTE
Inventor： SangKon Oh , Dapeng Li
IPC: A61K39/145 , A61K47/68 , A61K51/10 , C07K16/28 , C07K14/005 , C07K14/195 , C07K14/37 , C07K14/405 , C07K14/435 , C12N5/0784 , C12N7/00 , A61K39/00
Abstract: The present invention includes compositions and methods for making and using anti DC-ASGPR antibodies that can, e.g., activate DCs and other cells.
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公开(公告)号：US20210024641A1
公开(公告)日：2021-01-28
申请号：US16946302
申请日：2020-06-15
Applicant: BAYLOR RESEARCH INSTITUTE
Inventor： Jacques F. Banchereau , Gerard Zurawski , Sandra Zurawski , SangKon Oh
IPC: C07K16/28 , C07K14/005
Abstract: The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccine and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.
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18.发明授权公开(公告)号：US10279030B2
公开(公告)日：2019-05-07
申请号：US15265236
申请日：2016-09-14
Applicant: BAYLOR RESEARCH INSTITUTE
Inventor： SangKon Oh , Dapeng Li
IPC: A61K39/00 , A61K39/395 , A01N63/00 , A61K39/145 , A61K51/10 , C07K16/28 , C07K14/005 , C07K14/195 , C07K14/37 , C07K14/405 , C07K14/435 , C12N5/0784 , C12N7/00 , A61K47/68
Abstract: The present invention includes compositions and methods for making and using anti DC-ASGPR antibodies that can, e.g., activate DCs and other cells.
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公开(公告)号：US20170114142A1
公开(公告)日：2017-04-27
申请号：US15401856
申请日：2017-01-09
Applicant: BAYLOR RESEARCH INSTITUTE
Inventor： Jacques F. Banchereau , Gerard Zurawski , Sandra Zurawski , SangKon Oh
IPC: C07K16/28
CPC classification number: C07K16/2878 , A61K39/00 , A61K2039/6056 , C07K14/005 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/74 , C07K2317/80 , C07K2319/00 , C12N2740/16222 , C12N2740/16322
Abstract: The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccine and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.
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公开(公告)号：US20140234344A1
公开(公告)日：2014-08-21
申请号：US14165400
申请日：2014-01-27
Applicant: Baylor Research Institute
Inventor： Jacques F. Banchereau , Gerard Zurawski , Sandra Zurawski , SangKon Oh
IPC: C07K16/28
CPC classification number: C07K16/2878 , A61K39/00 , A61K2039/6056 , C07K14/005 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/74 , C07K2317/80 , C07K2319/00 , C12N2740/16222 , C12N2740/16322
Abstract: The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccines and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.
Abstract translation: 本发明包括用于表达，分泌和使用用作例如疫苗和抗原递送载体的用于将抗原递送至抗原呈递细胞的组合物和方法。 在一个实施方案中，载体是抗CD40抗体或其片段，以及与抗-CD40抗体或其片段（包括人源化抗体）连接的一个或多个抗原肽。
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