Molecular imaging of living subjects using Raman spectroscopy and labeled Raman nanoparticles
    13.
    发明授权
    Molecular imaging of living subjects using Raman spectroscopy and labeled Raman nanoparticles 有权
    使用拉曼光谱和标记拉曼纳米粒子的活体受体的分子成像

    公开(公告)号:US08795628B2

    公开(公告)日:2014-08-05

    申请号:US12598780

    申请日:2008-05-05

    IPC分类号: A61K51/00 A61K49/00

    CPC分类号: G01N21/658 B82Y30/00

    摘要: Methods of imaging a living host using Raman nanoparticles; methods of generating a true image of a living host having been administered Raman nanoparticles; methods of multiplex imaging of a living host using a plurality of Raman nanoparticles; methods of generating multimodality images by combining Raman images with other functional/anatomical images; labeled Raman nanoparticles; and the like, are provided.

    摘要翻译: 使用拉曼纳米颗粒成像活体的方法; 产生已经施用拉曼纳米粒子的活体的真实图像的方法; 使用多个拉曼纳米粒子对活体进行多重成像的方法; 通过将拉曼图像与其他功能/解剖图像组合来产生多模态图像的方法; 标记的拉曼纳米颗粒; 等等。

    Controlling a pressure transient in a well
    17.
    发明授权
    Controlling a pressure transient in a well 有权
    控制井中的压力瞬变

    公开(公告)号:US07036594B2

    公开(公告)日:2006-05-02

    申请号:US10701309

    申请日:2003-11-04

    IPC分类号: E21B43/25

    摘要: A system for controlling a dynamic pressure transient in a well during operations to provide fluid communication between the wellbore and adjacent formation. A method includes determining the characteristics of an adjacent formation, selecting a perforating tool for increasing fluid communication, determining a dynamic pressure transient to enhance the quality of the fluid communication and prevent damage, selecting a wellbore fluid to achieve the desired pressure transient, and performing the fluid communication process based on the selected parameters.

    摘要翻译: 一种用于在操作期间控制井中的动态压力瞬变以在井筒和相邻地层之间提供流体连通的系统。 一种方法包括确定相邻地层的特征,选择用于增加流体连通的穿孔工具,确定动态压力瞬变以提高流体连通的质量并防止损坏,选择井眼流体以实现期望的压力瞬变,以及执行 基于所选参数的流体通信过程。

    Reservoir communication with a wellbore

    公开(公告)号:US06598682B2

    公开(公告)日:2003-07-29

    申请号:US09797209

    申请日:2001-03-01

    IPC分类号: E21B2900

    摘要: A method and apparatus for improving reservoir communication includes, in one arrangement, use of one or more chambers to create an underbalance condition and/or a fluid surge in the wellbore. In another arrangement, a tool string comprises a packer, a circulating valve, and an atmospheric chamber, in which the circulating valve, when open, is adapted to vent a lower wellbore region below the packer when the packer is set, and the atmospheric chamber is capable of being operated to create an underbalance condition below the packer. In yet another arrangement, an apparatus comprises a subsea wellhead equipment including a blow-out preventer, choke line filled with a low density fluid, and a kill line filled with a heavy fluid. The choke line is adapted to be opened to create an underbalance condition in the wellbore. In yet another arrangement, a method of creating an underbalance condition comprises controlling wellbore pressure at least in a perforating interval to achieve a target level, configuring a perforating gun to achieve a target detonation pressure in the perforating gun upon detonation, and creating an underbalance condition in the perforating interval of the wellbore when the perforating gun is shot. In yet another arrangement, a tool string for use in a wellbore extending from a well surface comprises a closure member adapted to be positioned below the well surface, and a chamber defined at least in part by the closure member. The tool string further comprises at least a port selectively openable to enable communication between the chamber and a wellbore region. The port when open creates a fluid surging to the chamber to provide a low pressure condition in the wellbore region. A tool in the tool string is adapted to perform an operation in the low pressure condition.