公开(公告)号：US20220348973A1

公开(公告)日：2022-11-03

申请号：US17423262

申请日：2021-01-21

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jee Yeon Bae ,  Byoung Hoon Yoon ,  Su Yon Kwon ,  Kyungrim Kim ,  Ju Eun Kim ,  Hyo Jeong Byun ,  Seung Hyun Cho ,  Nara Kwon ,  Hyung Joon Kim

IPC: C12P13/04 ,  C12N9/02 ,  C12N1/20 ,  C12N15/77

Abstract: The present disclosure relates to a microorganism of the genus Corynebacterium having an increased L-amino acid producing ability, containing NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from the genus Lactobacillus. According to the present disclosure, the NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from Lactobacillus delbrueckii subsp. bulgaricus is introduced to increase the reducing power through the activity of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, thereby increasing the L-amino acid producing ability of the strains belonging to the genus Corynebacterium.

公开(公告)号：US11345940B2

公开(公告)日：2022-05-31

申请号：US16461490

申请日：2018-12-18

Applicant: CJ Cheiljedang Corporation

Inventor： Seon Hye Kim ,  Hyung Joon Kim ,  Haena Oh ,  Byoung Hoon Yoon ,  Min Gyeong Kang

IPC: C12P13/10 ,  C07K14/34 ,  C12N1/20 ,  C12N15/77

Abstract: A microorganism of the genus Corynebacterium producing L-arginine, and a method for producing L-arginine using the same.

公开(公告)号：US10703783B2

公开(公告)日：2020-07-07

申请号：US15754350

申请日：2016-07-27

Applicant: CJ Cheiljedang Corporation

Inventor： Seung Bin Lee ,  Yoon Hee Chung ,  Hyung Joon Kim ,  Doo Jin Kang ,  Seong Eun Bang ,  Song Gi Ryu

IPC: C12P13/08 ,  C07K14/34 ,  C12N15/77 ,  C12R1/15

Abstract: The present invention relates to an L-lysine-producing microorganism of the genus Corynebacterium and a method for producing L-lysine using the same.

公开(公告)号：US20190292526A1

公开(公告)日：2019-09-26

申请号：US16426453

申请日：2019-05-30

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Lan Huh ,  Jun Ok Moon ,  Hyun Won Bae ,  Hyung Joon Kim ,  Sung Ki Song

IPC: C12N9/02 ,  C12N15/77 ,  C12P13/04 ,  C12P13/08

Abstract: The present disclosure relates to a novel pyruvate dehydrogenase variant, a polynucleotide encoding the pyruvate dehydrogenase variant, a microorganism of the genus Corynebacterium producing L-amino acid, which includes the pyruvate dehydrogenase variant, and a method for producing an L-amino acid using the microorganism.

公开(公告)号：US09562246B2

公开(公告)日：2017-02-07

申请号：US14784621

申请日：2014-04-16

Applicant: CJ Cheiljedang Corporation

Inventor： Hyung Joon Kim ,  Ju No Jang ,  Kyung Rim Kim ,  Keun Cheol Lee ,  Young Bin Hwang ,  Hyeong Pyo Hong

IPC: C12P13/22 ,  C12N9/10

CPC classification number: C12P13/227 ,  C12N9/1077 ,  C12Y204/02018 ,  Y02P20/52

Abstract: The present invention relates to a microorganism of the genus Escherichia having enhanced L-tryptophan productivity, which has been modified to express yeast anthranilate phosphoribosyltransferase in order to be able to produce L-tryptophan at high concentration, and to a method for producing L-tryptophan, comprising a step of culturing the microorganism. The microorganism of the genus Escherichia can produce L-tryptophan, and thus can be advantageously used in the pharmaceutical industry and the feed industry, particularly for animal feed.

Abstract translation: 本发明涉及具有增强的L-色氨酸生产力的埃希氏菌属微生物，其已被修饰以表达酵母邻氨基苯甲酸酯磷酸核糖转移酶，以便能够产生高浓度的L-色氨酸，以及L-色氨酸的生产方法 包括培养微生物的步骤。 埃希氏菌属的微生物可产生L-色氨酸，因此可有利地用于制药工业和饲料工业，尤其用于动物饲料。

公开(公告)号：US20160040200A1

公开(公告)日：2016-02-11

申请号：US14923825

申请日：2015-10-27

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： So Yeon Rah ,  Lan Huh ,  Chang Gyeom Kim ,  Kwang Ho Lee ,  Jun Ok Moon ,  Kyung Han Lee ,  Jin Seok Sung ,  Hyung Joon Kim

IPC: C12P13/08 ,  C12N9/12 ,  C12N9/92

CPC classification number: C12P13/08 ,  C12N9/1205 ,  C12N9/92 ,  C12Y207/01017 ,  C12Y503/01005 ,  Y02P20/52

Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.

Abstract translation: 本发明涉及能够利用木糖的棒状杆菌的微生物和使用其的L-赖氨酸的制造方法。 更具体地，本发明涉及被修饰的棒状杆菌的微生物，其中引入木糖异构酶和木酮糖激酶的基因是木糖合成酶来表达木糖合酶。 本发明还涉及L-赖氨酸的制造方法，其特征在于，包括使用木糖作为碳源培养棒状杆菌的修饰微生物并从培养物中回收L-赖氨酸的步骤。

公开(公告)号：US12173341B2

公开(公告)日：2024-12-24

申请号：US17423262

申请日：2021-01-21

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jee Yeon Bae ,  Byoung Hoon Yoon ,  Su Yon Kwon ,  Kyungrim Kim ,  Ju Eun Kim ,  Hyo Jeong Byun ,  Seung Hyun Cho ,  Nara Kwon ,  Hyung Joon Kim

IPC: C12P13/04 ,  C12N1/20 ,  C12N9/02 ,  C12N15/77 ,  C12R1/15

Abstract: The present disclosure relates to a microorganism of the genus Corynebacterium having an increased L-amino acid producing ability, containing NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from the genus Lactobacillus. According to the present disclosure, the NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from Lactobacillus delbrueckii subsp. bulgaricus is introduced to increase the reducing power through the activity of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, thereby increasing the L-amino acid producing ability of the strains belonging to the genus Corynebacterium.

公开(公告)号：US20230056278A1

公开(公告)日：2023-02-23

申请号：US17790619

申请日：2021-04-02

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Cheol Woong Ha ,  Yeong Eun Im ,  Eun Bin Yang ,  Yeonsoo Kim ,  Hyung Joon Kim

IPC: C12P21/02 ,  C12N15/81 ,  C12N9/00

Abstract: Provided are a novel promoter, a vector including the same, a microorganism including the same, and a method of producing glutathione using the same.

公开(公告)号：US11293014B2

公开(公告)日：2022-04-05

申请号：US16484315

申请日：2019-04-09

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyungrim Kim ,  Hyo Jeong Byun ,  Kwang Woo Lee ,  Hyung Joon Kim ,  Yong Uk Shin ,  Jung Kee Lee

IPC: C12N9/26 ,  C12N1/20 ,  C12P13/04 ,  C12P13/06 ,  C12P13/08

Abstract: The present disclosure relates to a microorganism for producing an L-amino acid with enhanced activity of α-glucosidase and a method for producing an L-amino acid using the same. According to the present disclosure, the microorganism of the genus Corynebacterium producing an L-amino acid has enhanced activity of α-glucosidase, thereby improving L-amino acid production yield. Therefore, the microorganism may be very usefully used for L-amino acid production.

公开(公告)号：US11180784B2

公开(公告)日：2021-11-23

申请号：US16344205

申请日：2019-01-25

Applicant: CJ Cheiljedang Corporation

Inventor： Seung-ju Son ,  Byoung Hoon Yoon ,  Kwang Woo Lee ,  Seon Hye Kim ,  Hyo Jeong Byun ,  Jin Sook Chang ,  Hyung Joon Kim ,  Yong Uk Shin

IPC: C12P13/08 ,  C07K14/34

Abstract: A microorganism of the genus Corynebacterium producing L-amino acids, and a method of producing L-amino acids using the same.