摘要:
Pyrogallol or a salt thereof is prepared by a process comprising deoximating cyclohexane-1,2,3-trione oxime or an oxime derivative thereof or a salt of either. Preferably the oxime itself is exployed, especially the 1,3-dioxime. The deoximation is preferably effected by hydrolysis.
摘要:
A wedge-shaped whipstock is provided for directional well drilling which tapers from the lead end to a thick section at the bottom, and is fabricated from a tough polymeric material. An adhesive coating is applied to the outside surface of the wedge for permanent adherence of the whipstock to the surface of the drill hole. A deformable highly viscous material can fill and complement the internal wedge portion to produce a cylindrical configuration prior to use. Alternatively, or in conjunction with the deformable viscous material, a compressive element having a shaped compression face and made from a frangible material may be formed on the drill bit and/or attached to the prepared whipstock for the lowering of the tool into the drill hole and bonding the whipstock in place. The bottom surface of the whipstock is reinforced for positioning in the hole over a bridge plug or broken drill pipe. The weight of the drill bit and stem applied to the compressive element deforms the viscous filler material and laterally sets the whipstock in the hole. Rotation of the drill bit destroys the compressive element; and the drill, following the face of the wedge, drills an offset hole at an angle to the original. Various attachments, arrangements, and materials are provided for the whipstock wedge, filler portion and compressive element.
摘要:
The invention provides a method of monitoring a subject's neurological condition. In some embodiments, the method includes the steps of analyzing a physiological signal (such as an EEG) from a subject to determine if the subject is in a contra-ictal condition; and if the subject is in a contra-ictal condition, providing an indication (e.g., to the subject and/or to a caregiver) that the subject is in the contra-ictal condition, such as by activating a green light or other visible output. In some embodiments, if the subject is in a pro-ictal condition, the method includes the step of providing an indication (such as a red light) that the subject is in the pro-ictal condition. The invention also provides neurological system monitors.
摘要:
Systems and methods of monitoring a subject's neurological condition are provided. In some embodiments, the method includes the steps of analyzing a physiological signal (such as an EEG) from a subject to determine if the subject is in a contra-ictal condition; and if the subject is in a contra-ictal condition, providing an indication (e.g., to the subject and/or to a caregiver) that the subject is in the contra-ictal condition. The systems and methods may utilize a minimally invasive, leadless device to monitor the subject's condition. In some embodiments, if the subject is in a pro-ictal condition, the method includes the step of providing an indication (such as a red light) that the subject is in the pro-ictal condition.
摘要:
A head gimbal assembly includes a slider assembly and a flexure tongue that cantilevers in a first direction and supports the slider assembly. The slider assembly cantilevers away from the flexure tongue in a second direction different than the first direction. A load beam imparts a force on the flexure tongue and generates a first net torque on the slider assembly. The cantilevering of the slider assembly decreases a magnitude of the first net torque on the slider assembly. The force on the flexure tongue can also generate a second net torque on the slider assembly that is oriented about a second axis different than the first axis. The slider assembly can cantilever in the second direction to decrease the magnitude of the second net torque on the slider assembly. Portions of the flexure tongue and the slider assembly can be spaced apart from one another to form a gap that is directly between the flexure tongue and the slider assembly. The flexure tongue can includes a tongue aperture and/or one or more notches that increase the deflection of the flexure tongue to decrease the first net torque.
摘要:
Systems and methods of monitoring a subject's neurological condition are provided. In some embodiments, the method includes the steps of analyzing a physiological signal (such as an EEG) from a subject to determine if the subject is in a contra-ictal condition; and if the subject is in a contra-ictal condition, providing an indication (e.g., to the subject and/or to a caregiver) that the subject is in the contra-ictal condition. The systems and methods may utilize a minimally invasive, leadless device to monitor the subject's condition. In some embodiments, if the subject is in a pro-ictal condition, the method includes the step of providing an indication (such as a red light) that the subject is in the pro-ictal condition.
摘要:
A system for providing alerts of neurological events occurring in a human subject is provided. The system includes: a monitoring module adapted to detect and sample a neurological signal; an event detection module coupled to the monitoring module for detecting one or more types of predetermined reportable events based on the detected neurological signal; and an alert module coupled to the event detection module, wherein upon the detection of a reportable event by the event detection module, said alert module selects a first alert contact from a plurality of contacts contained in a contact list, and generates a first alert communication to the first alert contact.
摘要:
The present invention provides systems and methods for ambulatory, long term monitoring of a physiological signal from a patient. At least a portion of the systems of the present invention may be implanted within the patient in a minimally invasive manner. In preferred embodiments, brain activity signals are sampled from the patient and are transmitted to a handheld patient communication device for further processing.