公开(公告)号：US20230210418A1

公开(公告)日：2023-07-06

申请号：US18091984

申请日：2022-12-30

Applicant: DexCom, Inc.

Inventor： John Charles Barry ,  Elshad Abdullayev ,  Eunsook Chae Barber ,  Patrick J. Castagna ,  John Durham ,  Craig Thomas Gadd ,  Carl E. Hoffmeier ,  Nicholas Kalfas ,  Mark Kempkey ,  Young Woo Lee ,  Nicolas Medjo ,  Carl Pettersen ,  Will Reyna ,  Morgan Alexander Robinson ,  Samuel Rogers ,  Jeffrey J. Smith ,  Terry Thom ,  Shanger Wang ,  James Woodward

IPC: A61B5/1473 ,  A61B5/145 ,  A61B5/00

CPC classification number: A61B5/1473 ,  A61B5/14532 ,  A61B5/6833 ,  A61B5/6849

Abstract: Implementations relate generally to devices for measuring an analyte in a host. Implementations may provide reduced sizes for wearable devices including a transcutaneous analyte sensor for analyte measurement.

公开(公告)号：US20210361200A1

公开(公告)日：2021-11-25

申请号：US17342071

申请日：2021-06-08

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Minglian Shi ,  Sebastian Bohm ,  Maria Noel Brown Wells ,  John Patrick Majewski ,  Leah Morta Edra ,  Disha B. Sheth ,  John Michael Gray ,  Shanger Wang ,  Ted Tang Lee ,  Michael L. Moore ,  Jason Mitchell ,  Jennifer Blackwell ,  Neel Narayan Shah ,  Todd Andrew Newhouse ,  Jason Halac ,  Ryan Everett Schoonmaker ,  Paul V. Neale ,  Jiong Zou ,  Sean T. Saint

IPC: A61B5/145 ,  A61B5/00

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

公开(公告)号：US20210356420A1

公开(公告)日：2021-11-18

申请号：US17390668

申请日：2021-07-30

Applicant: DexCom, Inc.

Inventor： Ted Tang Lee ,  Shanger Wang ,  Jiong Zou

IPC: G01N27/327 ,  C08G18/08 ,  C08G18/48 ,  C08G18/40 ,  C08G18/38 ,  C08G18/12 ,  C08G18/44 ,  C08G18/75 ,  C08L39/06 ,  C08L69/00 ,  C08L75/04 ,  C12Q1/00 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  G01N33/66 ,  A61K31/045 ,  A61K31/137 ,  A61K31/46 ,  A61K31/465 ,  A61K31/485 ,  A61K31/515 ,  A61K31/56 ,  A61K33/00 ,  A61K36/185 ,  A61K38/28 ,  A61B5/1473 ,  C12N11/08

Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.

公开(公告)号：US20180116572A1

公开(公告)日：2018-05-03

申请号：US15798064

申请日：2017-10-30

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Minglian Shi ,  Sebastian Bohm ,  John Patrick Majewski ,  Maria Noel Brown Wells ,  Leah Ebuen Morta ,  Disha B. Sheth ,  John Michael Gray ,  Shanger Wang ,  Ted Tang Lee ,  Michael L. Moore ,  Jason Mitchell ,  Jennifer Blackwell ,  Neel Narayan Shah ,  Todd Andrew Newhouse ,  Jason Halac ,  Ryan Everett Schoonmaker ,  Paul V. Neale ,  Jiong Zou ,  Sean T. Saint

IPC: A61B5/145

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

公开(公告)号：US20180116570A1

公开(公告)日：2018-05-03

申请号：US15798249

申请日：2017-10-30

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Minglian Shi ,  Sebastian Bohm ,  Maria Noel Brown Wells ,  John Patrick Majewski ,  Leah Ebuen Morta ,  Disha B. Sheth ,  John Michael Gray ,  Shanger Wang ,  Ted Tang Lee ,  Michael L. Moore ,  Jason Mitchell ,  Jennifer Blackwell ,  Neel Narayan Shah ,  Todd Andrew Newhouse ,  Jason Halac ,  Ryan Everett Schoonmaker ,  Paul V. Neale ,  Jiong Zou ,  Sean T. Saint

IPC: A61B5/145 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/0004 ,  A61B5/0015 ,  A61B5/14503 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/683 ,  A61B5/6849 ,  A61B2560/045

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

公开(公告)号：US20170188922A1

公开(公告)日：2017-07-06

申请号：US15394706

申请日：2016-12-29

Applicant: DexCom, Inc.

Inventor： Ted Tang Lee ,  Andrew Trinin Dennis ,  Shanger Wang ,  Jiong Zou

IPC: A61B5/1486 ,  A61K36/185 ,  A61K31/46 ,  A61K38/28 ,  A61K31/045 ,  A61B5/00 ,  A61K31/465 ,  A61K31/56 ,  A61K31/137 ,  A61K31/515 ,  A61B5/145 ,  A61K33/00 ,  A61K31/485

CPC classification number: G01N27/3273 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2562/12 ,  A61K31/045 ,  A61K31/137 ,  A61K31/46 ,  A61K31/465 ,  A61K31/485 ,  A61K31/515 ,  A61K31/56 ,  A61K33/00 ,  A61K36/185 ,  A61K38/28 ,  C08G18/0828 ,  C08G18/12 ,  C08G18/3857 ,  C08G18/4018 ,  C08G18/44 ,  C08G18/4833 ,  C08G18/755 ,  C08L39/06 ,  C08L69/00 ,  C08L75/04 ,  C12N11/08 ,  C12Q1/002 ,  C12Q1/006 ,  G01N27/3275 ,  G01N33/66 ,  C08G18/3234

Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises a biointerface layer which interfaces with a biological fluid containing the analyte to be measured. The biointerface layer comprises a biointerface polymer, wherein the biointerface polymer comprises polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The biointerface layer increases sensor longevity and decrease sensor inaccuracy by inhibiting accumulation of cells, proteins, and other biological species on the outermost layers of the sensor.

公开(公告)号：US20160338733A1

公开(公告)日：2016-11-24

申请号：US15160516

申请日：2016-05-20

Applicant: DexCom, Inc.

Inventor： Neel Shah ,  Jennifer Blackwell ,  Jonathan Hughes ,  Ted Tang Lee ,  Peter C. Simpson ,  Shanger Wang

IPC: A61B17/34 ,  A61B5/145

CPC classification number: A61B17/3468 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14865 ,  A61B2017/3456 ,  A61B2560/063 ,  A61M5/3286

Abstract: The present disclosure relates to a needle including a wall structure, a cutting edge and a blunt contour. The needle advantageously can be used to deliver a sensor (such as a glucose or other analyte sensor) through an outer skin layer and into a sensor depth in a less invasive way than prior art needles. The size of the cutting edge is balanced against a portion of the distal wall structure that has blunt contours. Thus, the needle is capable of cutting the more durable outer skin layer (first phase) and then progressively stretching open the cut for further advancement into the subcutaneous layer (second phase). When the needle is sufficiently advanced, it is retracted leaving the sensor in a desired position. Early testing has shown a reduction of “dip and recover” from glucose sensors delivered using the needle.

公开(公告)号：US20240215876A1

公开(公告)日：2024-07-04

申请号：US18091889

申请日：2022-12-30

Applicant: DexCom, Inc.

Inventor： John Charles Barry ,  Elshad Abdullayev ,  Eunsook Chae Barber ,  Patrick J. Castagna ,  John Durham ,  Craig Thomas Gadd ,  Carl E. Hoffmeier ,  Nicholas Kalfas ,  Mark Kempkey ,  Young Woo Lee ,  Nicolas Medjo ,  Carl Pettersen ,  Will Reyna ,  Morgan Alexander Robinson ,  Samuel Rogers ,  Jeffrey J. Smith ,  Terry Thom ,  Shanger Wang ,  James Woodward

IPC: A61B5/1477 ,  A61B5/145

CPC classification number: A61B5/1477 ,  A61B5/14532

Abstract: Implementations relate generally to devices for measuring an analyte in a host. Implementations may provide reduced sizes for wearable devices including a transcutaneous analyte sensor for analyte measurement.

公开(公告)号：US20240138720A1

公开(公告)日：2024-05-02

申请号：US18516661

申请日：2023-11-21

Applicant: Dexcom, Inc.

Inventor： Ted Tang Lee ,  Andrew Trinin Dennis ,  Shanger Wang ,  Jiong Zou

IPC: A61B5/145

CPC classification number: A61B5/14532

Abstract: Disclosed are devices for determining an analyte concentration. The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and an electronics unit operatively connected to the sensor. The electronics unit may be engaged with a housing that may secure the device to a host's skin. In this regard, in one embodiment, the housing may be attached to an adhesive patch that is fastened to the skin of the host.

公开(公告)号：US20230293067A1

公开(公告)日：2023-09-21

申请号：US18201114

申请日：2023-05-23

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Jennifer Blackwell ,  Sebastian Bohm ,  Michael J. Estes ,  Jeff Jackson ,  Jason Mitchell ,  Jack Pryor ,  Daiting Rong ,  Sean T. Saint ,  Disha B. Sheth ,  Shanger Wang

IPC: A61B5/1473 ,  A61B5/145

CPC classification number: A61B5/1473 ,  A61B5/14532

Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.