公开(公告)号：US20230301563A1

公开(公告)日：2023-09-28

申请号：US18182941

申请日：2023-03-13

Applicant: Dexcom, Inc.

Inventor： Peter C. Simpson ,  Robert Boock ,  Paul V Neale ,  Sebastian Bohm ,  Matthew D. Wightlin ,  Jack Pryor ,  Jason Mitchell ,  Jeff Jackson ,  Kaushik Patel ,  Antonio C. Lievares

IPC: A61B5/1473 ,  A61B5/1486 ,  B05C3/12 ,  B05C3/02 ,  B23K26/362 ,  A61B5/145 ,  B05C3/10

CPC classification number: A61B5/1473 ,  A61B5/14865 ,  B05C3/125 ,  B05C3/02 ,  B23K26/362 ,  A61B5/14532 ,  B05C3/10 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14503 ,  A61B5/14546 ,  A61B2560/0223 ,  A61B2562/043 ,  A61B2562/125 ,  A61B2562/0209 ,  B05C5/0241

Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802′, 802″ formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

公开(公告)号：US20230293067A1

公开(公告)日：2023-09-21

申请号：US18201114

申请日：2023-05-23

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Jennifer Blackwell ,  Sebastian Bohm ,  Michael J. Estes ,  Jeff Jackson ,  Jason Mitchell ,  Jack Pryor ,  Daiting Rong ,  Sean T. Saint ,  Disha B. Sheth ,  Shanger Wang

IPC: A61B5/1473 ,  A61B5/145

CPC classification number: A61B5/1473 ,  A61B5/14532

Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.

公开(公告)号：US20230284944A1

公开(公告)日：2023-09-14

申请号：US18198085

申请日：2023-05-16

Applicant: Dexcom, Inc.

Inventor： Shanger Wang ,  Devon M. Headen ,  Sebastian Bohm ,  Jonathan Hughes ,  Ted Tang Lee ,  Peter C. Simpson ,  Jiong Zou

IPC: A61B5/1486 ,  A61B5/00 ,  C12Q1/00 ,  A61B5/145 ,  C12Q1/54

CPC classification number: A61B5/14865 ,  A61B5/0022 ,  C12Q1/006 ,  C12Q1/002 ,  A61B5/14532 ,  A61B5/14546 ,  C12Q1/54 ,  G01N27/3271

Abstract: Flexible analyte sensors are provided. Flexible analyte sensors may be flexible continuous analyte sensors that facilitate continuous monitoring of an analyte such as blood glucose. The flexible analyte sensor may have a relatively flexible conductive or non-conductive core, may be formed from a plurality of substantially planar layers, or may be configured to transform from a freestanding sensor ex vivo to a non-freestanding sensor in vivo.

公开(公告)号：US11677443B1

公开(公告)日：2023-06-13

申请号：US18163241

申请日：2023-02-01

Applicant: Dexcom, Inc.

Inventor： Thomas Miller ,  Mark Dervaes ,  Phong Lieu ,  Peter C. Simpson ,  Shawn Larvenz ,  Jacob S. Leach ,  Sebastian Bohm

IPC: H04B5/00 ,  H04W76/14 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495 ,  G01N27/327 ,  H04W12/06 ,  H04W4/80 ,  H04W52/02 ,  H04B5/02

CPC classification number: H04B5/0031 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/14532 ,  G01N27/3271 ,  H04B5/0043 ,  H04W4/80 ,  H04W12/06 ,  H04W12/068 ,  H04W52/0229 ,  H04W76/14 ,  H04B5/02 ,  Y02D30/70

Abstract: Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises: activating a transceiver of a first communication device associated with an analyte sensor at a first time; and establishing a two-way communication channel with the second communication device; wherein the activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device.

公开(公告)号：US20230140651A1

公开(公告)日：2023-05-04

申请号：US18049924

申请日：2022-10-26

Applicant: Dexcom. Inc.

Inventor： Arturo Garcia ,  Peter C. Simpson ,  Apurv U. Kamath ,  Naresh C. Bhavaraju ,  Stephen J. Vanslyke

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495

Abstract: Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

公开(公告)号：US11510625B2

公开(公告)日：2022-11-29

申请号：US17592170

申请日：2022-02-03

Applicant: DexCom, Inc.

Inventor： John Michael Gray ,  Jennifer Blackwell ,  Paul V. Neale ,  Justen Deering England ,  Andrew Joncich ,  Cameron Brock ,  Peter C. Simpson ,  Thomas Metzmaker ,  Neel Narayan Shah ,  Mark Douglas Kempkey ,  Patrick John Castagna ,  Warren Terry ,  Jason Halac ,  Christian Michael Andre George ,  Daniel E. Apacible ,  John Charles Barry ,  Maria Noel Brown Wells ,  Kenneth Pirondini ,  Andrew Michael Reinhardt ,  Jason C. Wong ,  Remy E. Gagnon ,  David DeRenzy ,  Randall Scott Koplin ,  Alan Baldwin ,  Young Woo Lee ,  David A. Keller ,  Louise Emma van den Heuvel ,  Carol Wood Sutherland

IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/00

Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.

公开(公告)号：US11504063B2

公开(公告)日：2022-11-22

申请号：US17592199

申请日：2022-02-03

Applicant: DexCom, Inc.

Inventor： John Michael Gray ,  Jennifer Blackwell ,  Paul V. Neale ,  Justen Deering England ,  Andrew Joncich ,  Cameron Brock ,  Peter C. Simpson ,  Thomas Metzmaker ,  Neel Narayan Shah ,  Mark Douglas Kempkey ,  Patrick John Castagna ,  Warren Terry ,  Jason Halac ,  Christian Michael Andre George ,  Daniel E. Apacible ,  John Charles Barry ,  Maria Noel Brown Wells ,  Kenneth Pirondini ,  Andrew Michael Reinhardt ,  Jason C. Wong ,  Remy E. Gagnon ,  David DeRenzy ,  Randall Scott Koplin ,  Alan Baldwin ,  Young Woo Lee ,  David A. Keller ,  Louise Emma van den Heuvel ,  Carol Wood Sutherland

IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/00

Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.

公开(公告)号：US20220322975A1

公开(公告)日：2022-10-13

申请号：US17842624

申请日：2022-06-16

Applicant: DexCom, Inc.

Inventor： Joseph J. Baker ,  Philip Thomas Pupa ,  Timothy Joseph Goldsmith ,  Jonathan Bodnar ,  Jason Halac ,  John Michael Gray ,  Neal Davis Johnston ,  Justen Deering England ,  Peter C. Simpson ,  Paul V. Neale ,  Jennifer Blackwell ,  Maria Noel Brown Wells ,  Kenneth Pirondini ,  Andrew Michael Reinhardt ,  Mark Douglas Kempkey ,  Young Woo Lee ,  Warren Terry ,  Patrick John Castagna ,  David A. Keller ,  Randall Scott Koplin ,  Andrew Joncich ,  Nirav Bhatt

IPC: A61B5/145 ,  A61B5/00 ,  A61B17/34

Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

公开(公告)号：US11450421B2

公开(公告)日：2022-09-20

申请号：US16904454

申请日：2020-06-17

Applicant: DexCom, Inc.

Inventor： Anna Leigh Davis ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Rita M. Castillo ,  Alexandra Elena Constantin ,  Rian Draeger ,  Laura J. Dunn ,  Gary Brian Gable ,  Arturo Garcia ,  Thomas Hall ,  Hari Hampapuram ,  Christopher Robert Hannemann ,  Anna Claire Harley-Trochimczyk ,  Nathaniel David Heintzman ,  Andrea Jean Jackson ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Samuel Jere Marsh ,  Gary A. Morris ,  Subrai Girish Pai ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Ashley Anne Rindfleisch ,  Sofie Wells Schunk ,  Peter C. Simpson ,  Daniel Smith ,  Stephen J. Vanslyke ,  Matthew T. Vogel ,  Tomas C. Walker ,  Benjamin Elrod West ,  Atiim Joseph Wiley

IPC: G16H20/17 ,  G16H50/20 ,  G06N20/00 ,  A61B5/00 ,  H04M1/72412 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  G08B21/04 ,  G06N5/04 ,  A61M5/172 ,  G16H40/67 ,  G16H40/63

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

公开(公告)号：US20220240817A1

公开(公告)日：2022-08-04

申请号：US17719224

申请日：2022-04-12

Applicant: DexCom, Inc.

Inventor： Jason Halac ,  John Charles Barry ,  Becky L. Clark ,  Chris W. Dring ,  John Michael Gray ,  Kris Elliot Higley ,  Jeff Jackson ,  David A. Keller ,  Ted Tang Lee ,  Jason Mitchell ,  Kenneth Pirondini ,  David Rego ,  Ryan Everett Schoonmaker ,  Peter C. Simpson ,  Craig Thomas Gadd ,  Kyle Thomas Stewart ,  John Stanley Hayes

IPC: A61B5/1473 ,  A61B5/1486 ,  A61B5/145 ,  G01N27/327 ,  A61B5/1459 ,  G01N33/66 ,  A61B5/1495 ,  A61B5/00 ,  A61M15/00 ,  G16H20/17 ,  G16H40/63 ,  A61M5/142 ,  A61M5/172 ,  A61M5/20 ,  A61M11/00 ,  A61M35/00 ,  H05K3/32

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.