Low-mycotoxin coffee cherry products
    11.
    发明授权
    Low-mycotoxin coffee cherry products 有权
    低霉菌素咖啡樱桃制品

    公开(公告)号:US08597710B2

    公开(公告)日:2013-12-03

    申请号:US12899385

    申请日:2010-10-06

    IPC分类号: A23B7/00 A23F5/00

    摘要: A coffee cherry is harvested, preferably in a sub-ripe state, and quick-dried to provide a basis for numerous nutritional products. Such coffee cherries and portions thereof may be particularly characterized by their extremely low concentration of mycotoxins, including various aflatoxins, fumonisins, ochratoxins, and/or vomitoxin (DON, deoxynivalenol).

    摘要翻译: 收获咖啡樱桃,优选处于亚成熟状态,并快速干燥以提供许多营养产品的基础。 这样的咖啡樱桃及其部分可以特别地特征在于它们极微浓度的真菌毒素,包括各种黄曲霉毒素,伏马毒素,赭曲毒素和/或呕吐毒素(DON,脱氧雪腐镰刀菌烯醇)。

    PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION
    14.
    发明申请
    PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION 有权
    药物组合物和代谢调节方法

    公开(公告)号:US20090203638A1

    公开(公告)日:2009-08-13

    申请号:US12419950

    申请日:2009-04-07

    摘要: Pharmaceutical compositions include compounds with cytokinin activity to modulate glucose and/or lipid metabolism in a mammal. Especially preferred compounds include those comprising a purine scaffold, and it is further preferred that contemplated compositions are employed to prevent and/or treat various diseases, including pre-diabetes, insulin resistance, type-2 diabetes, Syndrome X, and dyslipidemia. In still further preferred aspects, compounds with cytokinin activity are used to activate AMPK and/or Akt. Consequently, various diseases associated with dysregulation of AMPK and/or Akt may be treated using the compounds of the present inventive subject matter.

    摘要翻译: 药物组合物包括具有细胞分裂素活性以调节哺乳动物中的葡萄糖和/或脂质代谢的化合物。 特别优选的化合物包括含有嘌呤支架的那些化合物,并且进一步优选的是,预期的组合物用于预防和/或治疗各种疾病,包括前期糖尿病,胰岛素抵抗,2型糖尿病,X综合征和血脂异常。 在另外的优选方面,使用具有细胞分裂素活性的化合物来活化AMPK和/或Akt。 因此,可以使用本发明主题的化合物治疗与AMPK和/或Akt失调相关的各种疾病。

    Compositions and methods for treating NIDDM and other conditions and disorders associated with AMPK regulation
    16.
    发明授权
    Compositions and methods for treating NIDDM and other conditions and disorders associated with AMPK regulation 有权
    用于治疗NIDDM和其他与AMPK调节相关的病症和障碍的组合物和方法

    公开(公告)号:US07320806B2

    公开(公告)日:2008-01-22

    申请号:US10526837

    申请日:2003-08-29

    IPC分类号: A61K36/8998

    CPC分类号: A61K36/00 A61K36/8998

    摘要: Compositions and methods are provided to increase glucose uptake in a cell as well as to treat a patient suffering from a condition or disorder associated with AMPK regulation. Particularly contemplated compositions include a compound that is isolated from a plant that has AICAR-like activity. In another aspect of the invention, contemplated compositions comprise a non-insulin compound that has AICAR-like activity and activates AMPK in a cell.

    摘要翻译: 提供组合物和方法以增加细胞中的葡萄糖摄取以及治疗患有与AMPK调节相关的病症或障碍的患者。 特别考虑的组合物包括从具有AICAR样活性的植物中分离的化合物。 在本发明的另一方面,预期的组合物包含具有AICAR样活性并在细胞中活化AMPK的非胰岛素化合物。

    Compositions and method for steroid homeostasis
    17.
    发明申请
    Compositions and method for steroid homeostasis 审中-公开
    类固醇体内平衡的组成和方法

    公开(公告)号:US20050032743A1

    公开(公告)日:2005-02-10

    申请号:US10648975

    申请日:2003-08-26

    申请人: Dusan Miljkovic

    发明人: Dusan Miljkovic

    摘要: Methods and compositions are directed to a dietary supplement comprising boron that is an a complex with a carbohydrate, wherein administration of the complex increases steroid levels, and particularly 25-hydroxy vitamin D3. Thus, contemplated compositions are useful for treatment of impaired steroid homeostasis, and especially beneficial for prevention and/or treatment of bone density loss. Particularly preferred compositions further include calcium, magnesium, and/or vitamin D in a nutritionally acceptable form.

    摘要翻译: 方法和组合物涉及包含与碳水化合物复合物的硼的膳食补充剂,其中配合物的施用增加了类固醇水平,特别是25-羟基维生素D3。 因此,预期的组合物可用于治疗受损的类固醇体内平衡,并且特别有利于预防和/或治疗骨密度损失。 特别优选的组合物还包括营养可接受的形式的钙,镁和/或维生素D.

    Metallic oligopeptide complexes
    18.
    发明授权
    Metallic oligopeptide complexes 失效
    金属寡肽复合物

    公开(公告)号:US6071545A

    公开(公告)日:2000-06-06

    申请号:US243762

    申请日:1999-02-03

    IPC分类号: A23L1/304 A23L1/305

    CPC分类号: A23L33/18 A23L33/165

    摘要: A composition of matter which comprises a metallic complex of the formulaM.sup.Z+ L.sub.n IwhereinM is a metal ion of nutritional or therapeutic value;L.sub.n is one or more oligopeptides wherein at least one oligopeptide comprises at least one amino acid selected from the group consisting of nonprotein amino acids and synthetic amino acids;n=1-3,Z=1-6. The metal ion of the metallic complex is selected from the group consisting of chromium, zinc, manganese, magnesium, calcium, copper, iron, vanadium, cobalt, molybdenum, germanium, selenium, and indium. The invention further provides food or drink compositions or dietary supplements which comprise the metallic complex of the invention.

    摘要翻译: 一种物质组合物,其包含式MZ + LnI的金属络合物,其中M是营养或治疗值的金属离子; Ln是一种或多种寡肽,其中至少一种寡肽包含至少一种选自非蛋白氨基酸和合成氨基酸的氨基酸; n = 1-3,Z = 1-6。 金属络合物的金属离子选自铬,锌,锰,镁,钙,铜,铁,钒,钴,钼,锗,硒和铟。 本发明还提供了包含本发明的金属络合物的食品或饮料组合物或膳食补充剂。