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公开(公告)号：US20200016435A1
公开(公告)日：2020-01-16
申请号：US16032623
申请日：2018-07-11
Applicant: ELWHA LLC
Inventor： Jeffrey A. Bowers , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Jay Pierce , Katherine E. Sharadin , Michael A. Smith , Marc Stein , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR.
Abstract: A nerve modulation device includes a first ultrasound transducer and a second ultrasound transducer. The first and second ultrasound transducers are configured to emit a first and second ultrasound waves, respectively, that exhibit different frequencies. The first and second ultrasound transducers can emit the first and second ultrasound waves in directions that are selected to cause the first and second ultrasound waves to intersect with each other at an intersection site that is at or near a selected nerve. At the intersection site, the first and second ultrasound waves can non-linearly interact to form an acoustic wave exhibiting a frequency that is less than the frequencies of the first and second ultrasound waves. The acoustic wave can modulate a selected nerve.
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公开(公告)号：US10265219B2
公开(公告)日：2019-04-23
申请号：US14252136
申请日：2014-04-14
Applicant: Elwha LLC
Inventor： Paul Duesterhoft , Nicholas Dykstra , Daniel Hawkins , Roderick A. Hyde , Jordin T. Kare , Eric C. Leuthardt , Elizabeth L. Schubert , Clarence T. Tegreene , Lowell L. Wood, Jr.
Abstract: Appurtenances to a wound dressing and systems for monitoring wound dressings are described. In some embodiments, a system for monitoring a wound dressing includes: an appurtenance to a wound dressing, wherein the appurtenance includes a sensor unit, an electronic identifier, and a transmitter unit operably attached to the sensor unit and to the electronic identifier; and a local unit including a receiver for the transmitter unit, a processor operably attached to the receiver, and a communication unit operably attached to the processor.
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公开(公告)号：US20180090124A1
公开(公告)日：2018-03-29
申请号：US15683517
申请日：2017-08-22
Applicant: Elwha LLC
Inventor： Jeffrey A. Bowers , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Clarence T. Tegreene , Lowell L. Wood, JR.
CPC classification number: G10K11/345 , G10K11/34 , G10K11/343 , H04R1/40 , H04R2201/401
Abstract: The present disclosure provides systems and methods associated with acoustic transmitters, receivers, and antennas. Specifically, the present disclosure provides a transducer system for transmitting and receiving acoustic energy according to a determined acoustic emission/reception pattern. In various embodiments, an acoustic transducer system may include an array of sub-wavelength transducer elements each configured with an electromagnetic resonance at one of a plurality of electromagnetic frequencies. Each sub-wavelength transducer element may generate an acoustic emission in response to the electromagnetic resonance. A beam-forming controller may cause electromagnetic energy to be transmitted at select electromagnetic frequencies to cause a select subset of the sub-wavelength transducer elements to generate acoustic emissions according to a selectable acoustic transmission pattern. A common port may facilitate electromagnetic communication with each of the sub-wavelength transducer elements.
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14.发明授权Device and method for detection and treatment of ventilator associated pneumonia in a mammalian subject 有权在哺乳动物受试者中用于检测和治疗呼吸机相关性肺炎的装置和方法公开(公告)号：US09480807B2
公开(公告)日：2016-11-01
申请号：US14044522
申请日：2013-10-02
Applicant: Elwha LLC
Inventor： Jeffrey A. Bowers , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Edward K. Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Gary L. McKnight , Nathan P. Myhrvold , Michael A. Smith , Clarence T. Tegreene , Lowell L. Wood, Jr.
CPC classification number: A61M16/044 , A61M16/0051 , A61M16/024 , A61M16/0443 , A61M16/0445 , A61M16/0459 , A61M2016/0027 , A61M2205/0205 , A61M2205/0266 , A61M2205/3303 , A61M2209/02
Abstract: Devices and methods are disclosed herein for preventing or treating ventilator associated pneumonia in a mammalian subject. The device includes an endotracheal tube having an interior surface and an exterior surface; and one or more closed cell layers in contact with the exterior surface and circumferentially surrounding one or more longitudinal portion of the endotracheal tube, wherein the closed cell layer is flexibly shaped to reversibly form a seal in a trachea of a mammalian subject.
Abstract translation: 本文公开了用于在哺乳动物受试者中预防或治疗呼吸机相关肺炎的装置和方法。 该装置包括具有内表面和外表面的气管内管; 以及与所述外表面接触并周向地包围所述气管插管的一个或多个纵向部分的一个或多个闭孔层，其中所述闭孔层被柔性地成形为在哺乳动物受试者的气管中可逆地形成密封。
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15.发明授权公开(公告)号：US09398955B2
公开(公告)日：2016-07-26
申请号：US14285968
申请日：2014-05-23
Applicant: Elwha LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Clarence T. Tegreene
CPC classification number: A61F2/30 , A61F2/30742 , A61F2/32 , A61F2/38 , A61F2/40 , A61F2002/30079 , A61F2002/30087 , A61F2002/30558 , A61F2002/30673 , A61F2002/30682 , A61F2002/30683 , A61F2002/3082 , A61F2002/3092 , A61F2002/3429 , A61F2002/3631 , A61F2002/482
Abstract: Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, an artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain non-physiological particles present within the synovial fluid.
Abstract translation: 描述了假肢人工关节，包括髋关节，膝关节和肩关节。 在一些实施例中，人造关节假体包括：人造关节假体的面向骨的表面，所述面向骨的表面构造成在体内面向骨假体界面; 人造关节假体的非接触表面，与人造关节假体的面向骨的表面相邻的非接触表面; 定位成邻近非接触表面定位的至少一个流体偏转结构，所述流体偏转结构被定位成使滑液在体内远离骨假体界面偏转; 附接到所述流体偏转结构的机构，所述机构可操作以移动所述流体偏转结构以将滑液体在体内远离所述骨假体界面引导; 以及至少一个颗粒保持结构，定位成接触滑液的定向流并被配置为保留存在于滑液内的非生理性颗粒。
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Patent Agency Ranking
16.发明申请公开(公告)号：US20150238691A1
公开(公告)日：2015-08-27
申请号：US14189255
申请日：2014-02-25
Applicant: Elwha LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Philip A. Eckhoff , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Gary L. McKnight , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Clarence T. Tegreene
CPC classification number: A61F2/30 , A61B5/1036 , A61B5/11 , A61F2/30742 , A61F2002/3067 , A61F2002/3068 , A61F2002/4666 , A61F2002/482 , A61F2250/0068 , A61F2250/0096 , A61M31/002 , A61M2205/3306 , A61M2205/3317 , A61M2205/332 , A61M2205/3523 , A61M2210/02 , A61M2230/63
Abstract: In some embodiments, a system for responsive release of a medicament in an artificial joint region includes: an implantable sensor unit including at least one sensor, the implantable sensor unit configured to be implanted in an artificial joint region; a responsive release control unit including an electronic controller and memory, the responsive release control unit configured to receive signals from the implantable sensor unit and to send signals to an implantable medicament release unit; and the implantable medicament release unit, including a reservoir and a controllable release unit attached to the reservoir, the controllable release unit configured to provide access to the reservoir in response to signals from the responsive release control unit, the implantable medicament release unit configured to be implanted in the artificial joint region.
Abstract translation: 在一些实施例中，用于药物在人造关节区域中的响应释放的系统包括：可植入传感器单元，其包括至少一个传感器，所述可植入传感器单元被配置为植入人造关节区域; 响应释放控制单元，包括电子控制器和存储器，所述响应释放控制单元被配置为从所述可植入传感器单元接收信号并将信号发送到可植入药物释放单元; 以及可植入药物释放单元，其包括附接到储存器的储存器和可控释放单元，所述可释放单元被配置为响应于来自所述响应释放控制单元的信号而提供对所述储存器的通路，所述可植入药物释放单元被配置为 植入人工关节区域。
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17.发明申请Device and Method for Detection and Treatment of Ventilator Associated Pneumonia in a Mammalian Subject 有权在哺乳动物受试者中呼吸机相关性肺炎的检测和治疗的装置和方法公开(公告)号：US20150090270A1
公开(公告)日：2015-04-02
申请号：US14044522
申请日：2013-10-02
Applicant: Elwha LLC
Inventor： Jeffrey A. Bowers , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Edward K.Y. Jung , Jordin T. Kare , Eric C. Leuthardt , Gary L. McKnight , Nathan P. Myhrvold , Michael A. Smith , Clarence T. Tegreene , Lowell L. Wood, JR.
CPC classification number: A61M16/044 , A61M16/0051 , A61M16/024 , A61M16/0443 , A61M16/0445 , A61M16/0459 , A61M2016/0027 , A61M2205/0205 , A61M2205/0266 , A61M2205/3303 , A61M2209/02
Abstract: Devices and methods are disclosed herein for preventing or treating ventilator associated pneumonia in a mammalian subject. The device includes an endotracheal tube having an interior surface and an exterior surface; and one or more closed cell layers in contact with the exterior surface and circumferentially surrounding one or more longitudinal portion of the endotracheal tube, wherein the closed cell layer is flexibly shaped to reversibly form a seal in a trachea of a mammalian subject.
Abstract translation: 本文公开了用于在哺乳动物受试者中预防或治疗呼吸机相关肺炎的装置和方法。 该装置包括具有内表面和外表面的气管内管; 以及与所述外表面接触并周向地包围所述气管插管的一个或多个纵向部分的一个或多个闭孔层，其中所述闭孔层被柔性地成形为在哺乳动物受试者的气管中可逆地形成密封。
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18.发明授权公开(公告)号：US08845740B2
公开(公告)日：2014-09-30
申请号：US13659020
申请日：2012-10-24
Applicant: Elwha LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Clarence T. Tegreene
CPC classification number: A61F2/30 , A61F2/30742 , A61F2/32 , A61F2/38 , A61F2/40 , A61F2002/30079 , A61F2002/30087 , A61F2002/30558 , A61F2002/30673 , A61F2002/30682 , A61F2002/30683 , A61F2002/3082 , A61F2002/3092 , A61F2002/3429 , A61F2002/3631 , A61F2002/482
Abstract: Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, an artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain non-physiological particles present within the synovial fluid.
Abstract translation: 描述了假肢人工关节，包括髋关节，膝关节和肩关节。 在一些实施例中，人造关节假体包括：人造关节假体的面向骨的表面，所述面向骨的表面构造成在体内面向骨假体界面; 人造关节假体的非接触表面，与人造关节假体的面向骨的表面相邻的非接触表面; 定位成邻近非接触表面定位的至少一个流体偏转结构，所述流体偏转结构被定位成使滑液在体内远离骨假体界面偏转; 附接到所述流体偏转结构的机构，所述机构可操作以移动所述流体偏转结构以将滑液体在体内远离所述骨假体界面引导; 以及至少一个颗粒保持结构，定位成接触滑液的定向流并被配置为保留存在于滑液内的非生理性颗粒。
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19.发明申请BREAST IMPLANT WITH REGIONALIZED ANALYTE SENSORS RESPONSIVE TO EXTERNAL POWER SOURCE 有权具有对外部电源响应的区域化分析仪传感器的乳腺植入公开(公告)号：US20140288647A1
公开(公告)日：2014-09-25
申请号：US14302814
申请日：2014-06-12
Applicant: Elwha LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
CPC classification number: A61F2/12 , A61B5/0031 , A61B5/14503 , A61B5/1451 , A61B5/14546 , A61B5/14735 , A61B5/4312 , A61B5/686 , A61B5/6867 , A61B2562/046 , A61F2250/0001 , A61F2250/0002
Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.
Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 从所述壳体的外表面延伸的多个突起，所述突起形成与所述壳体的外表面相邻的多个隔室; 至少一个液体可渗透的盖附接到突起，所述盖完全包围壳体和多个突起; 并且多个传感器模块附接到壳体并且彼此间隔一定距离，每个传感器模块被定向成检测多个隔室中的一个内的流体中的一种或多种分析物，其中多个传感器模块 包括唯一的标识符并被配置为利用从外部源发送的能量。
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20.发明申请公开(公告)号：US20140277519A1
公开(公告)日：2014-09-18
申请号：US14282811
申请日：2014-05-20
Applicant: Elwha LLC
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Clarence T. Tegreene
CPC classification number: A61F2/30 , A61F2/32 , A61F2/38 , A61F2/40 , A61F2002/30673
Abstract: Artificial joint prosthetic components including synovial fluid deflection structures are described. Embodiments of artificial joint prosthesis include those with: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis; and at least one fluid deflection structure positioned on the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo.
Abstract translation: 描述了包括滑液偏转结构在内的人造关节假体部件。 人造关节假体的实施例包括具有：人造关节假体的面向骨的表面的面向骨体的表面，所述骨对面表面构造成在体内面向骨假体界面; 人造关节假体的非接触表面; 以及定位在所述非接触表面上的至少一个流体偏转结构，所述流体偏转结构被定位成使滑液在体内远离骨假体界面偏转。
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