公开(公告)号：US10034743B2

公开(公告)日：2018-07-31

申请号：US14809389

申请日：2015-07-27

申请人： Elwha LLC

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/12 ,  A61B5/07 ,  A61B5/00 ,  A61B5/145

CPC分类号： A61F2/12 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/14546 ,  A61B5/4312 ,  A61B5/686 ,  A61B5/6867 ,  A61B2560/0219 ,  A61F2250/0085 ,  A61F2250/0096

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the plurality of sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.

公开(公告)号：US20170354281A1

公开(公告)日：2017-12-14

申请号：US15688977

申请日：2017-08-29

申请人： Elwha LLC

发明人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Jordin T. Kare ,  Robert Langer ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： A47G21/04 ,  A47G23/02 ,  A47G21/02 ,  A47G19/22

CPC分类号： A47G21/04 ,  A47G19/2227 ,  A47G21/02 ,  A47G23/0216 ,  A47G2400/04

摘要： In an aspect, an eating utensil includes a controllable odorant emitter for delivering an odorant to a person who is eating or drinking from the eating utensil. The odorant may be delivered orthonasally or retronasally. The odorant may be used to stimulate or suppress appetite. In an aspect, a controllable odorant emitter is provided in an attachment that may be removably secured to an eating utensil. Related methods and systems for delivering odorant in connection with use of an eating utensil are described.

公开(公告)号：US09550029B2

公开(公告)日：2017-01-24

申请号：US13664138

申请日：2012-10-30

申请人： Elwha LLC

发明人： Edward S. Boyden ,  Hon Wah Chin ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61M31/00 ,  A61M5/42 ,  A61F7/00

CPC分类号： A61M5/427 ,  A61B90/11 ,  A61B90/13 ,  A61B2090/364 ,  A61F7/00 ,  A61M2205/18 ,  A61M2205/50 ,  A61M2205/587 ,  G16H10/60 ,  Y02A90/26

摘要： Systems and methods are described herein for guided injection, which include: one or more controllable light-emitting elements configured to emit non-destructive light and a computing device operably connected to the one or more controllable light-emitting elements configured to emit non-destructive light, the computing device including a processor operable to receive at least one digital representation of a body region of an individual, the body region of the individual including one or more physical registration landmarks, the at least one digital representation including one or more digitally registered injection sites and one or more digital registration landmarks corresponding to the one or more physical registration landmarks on the body region; and control the one or more controllable light-emitting elements to illuminate a location of a surface of the body region of the individual corresponding in location to at least one of the one or more digitally registered injection sites.

摘要翻译： 本文描述了用于引导注入的系统和方法，其包括：被配置为发射非破坏性光的一个或多个可控发光元件和可操作地连接到被配置为发射非破坏性的一个或多个可控发光元件的计算设备 所述计算设备包括可操作以接收个人身体区域的至少一个数字表示的处理器，所述个体的身体区域包括一个或多个物理注册地标，所述至少一个数字表示包括一个或多个数字注册 注入位置和对应于身体区域上的一个或多个物理注册地标的一个或多个数字注册地标; 并且控制所述一个或多个可控发光元件以将位于所述个体的身体区域的表面的位置照射到所述一个或多个数字注册的注射位置中的至少一个。

公开(公告)号：US09387080B2

公开(公告)日：2016-07-12

申请号：US14282811

申请日：2014-05-20

申请人： Elwha LLC

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Clarence T. Tegreene

IPC分类号： A61F2/30 ,  A61F2/32 ,  A61F2/38 ,  A61F2/40

CPC分类号： A61F2/30 ,  A61F2/32 ,  A61F2/38 ,  A61F2/40 ,  A61F2002/30673

摘要： Artificial joint prosthetic components including synovial fluid deflection structures are described. Embodiments of artificial joint prosthesis include those with: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis; and at least one fluid deflection structure positioned on the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo.

摘要翻译： 描述了包括滑液偏转结构在内的人造关节假体部件。 人造关节假体的实施例包括具有：人造关节假体的面向骨的表面的面向骨体的表面，所述骨对面表面构造成在体内面向骨假体界面; 人造关节假体的非接触表面; 以及定位在所述非接触表面上的至少一个流体偏转结构，所述流体偏转结构被定位成使滑液在体内远离骨假体界面偏转。

公开(公告)号：US09339372B2

公开(公告)日：2016-05-17

申请号：US14302814

申请日：2014-06-12

申请人： Elwha LLC

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/12 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1473

CPC分类号： A61F2/12 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/4312 ,  A61B5/686 ,  A61B5/6867 ,  A61B2562/046 ,  A61F2250/0001 ,  A61F2250/0002

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.

摘要翻译： 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 从所述壳体的外表面延伸的多个突起，所述突起形成与所述壳体的外表面相邻的多个隔室; 至少一个液体可渗透的盖附接到突起，所述盖完全包围壳体和多个突起; 以及多个传感器模块，其附接到壳体并且彼此间隔一定距离，每个传感器模块被定向成检测多个隔室中的一个内的流体中的一种或多种分析物，其中多个传感器模块 包括唯一的标识符并被配置为利用从外部源发送的能量。

公开(公告)号：US09326730B2

公开(公告)日：2016-05-03

申请号：US14301077

申请日：2014-06-10

申请人： Elwha LLC

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/12 ,  A61B5/00 ,  A61B5/07

CPC分类号： A61B5/686 ,  A61B5/076 ,  A61B5/4312 ,  A61B5/4848 ,  A61B5/4851 ,  A61F2/12

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.

摘要翻译： 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 至少一个流体可透过的盖，所述盖完全包围所述壳; 以及多个传感器模块，其附接到壳体并且彼此间隔一定距离，每个传感器模块被定向成检测壳体和盖子之间的流体中的一种或多种分析物，其中多个传感器模块中的每一个包括 唯一的标识符并被配置为利用从外部源发送的能量。

公开(公告)号：US20140257496A1

公开(公告)日：2014-09-11

申请号：US14283572

申请日：2014-05-21

申请人： Elwha LLC

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Clarence T. Tegreene

IPC分类号： A61F2/30 ,  A61F2/38 ,  A61F2/40 ,  A61F2/32

CPC分类号： A61F2/30 ,  A61F2/30742 ,  A61F2/32 ,  A61F2/38 ,  A61F2/40 ,  A61F2002/30079 ,  A61F2002/30087 ,  A61F2002/30558 ,  A61F2002/30673 ,  A61F2002/30682 ,  A61F2002/30683 ,  A61F2002/3082 ,  A61F2002/3092 ,  A61F2002/3429 ,  A61F2002/3631 ,  A61F2002/482

摘要： Artificial joint prostheses, including hip, knee and shoulder joints, are described. In some aspects, an artificial joint prosthesis includes: a bone-facing surface of an artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure attached to the non-contact surface, the fluid deflection structure positioned to direct a flow of synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain particles present within the synovial fluid.

摘要翻译： 描述了人造关节假体，包括髋关节，膝关节和肩关节。 在一些方面，人造关节假体包括：人造关节假体的面向骨的表面，所述面向骨骼的表面构造成在体内面向骨假体界面; 人造关节假体的非接触表面，与人造关节假体的面向骨的表面相邻的非接触表面; 连接到非接触表面的至少一个流体偏转结构，所述流体偏转结构被定位成将滑液流在体内引导离开骨假体界面; 以及至少一个颗粒保持结构，定位成接触滑液的定向流并被构造成保留存在于滑液内的颗粒。

公开(公告)号：US20140088721A1

公开(公告)日：2014-03-27

申请号：US13675068

申请日：2012-11-13

申请人： ELWHA LLC

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Clarence T. Tegreene

IPC分类号： A61F2/30 ,  A61F2/38 ,  A61F2/40 ,  A61F2/32

CPC分类号： A61F2/30 ,  A61F2/30742 ,  A61F2/32 ,  A61F2/38 ,  A61F2/40 ,  A61F2002/30079 ,  A61F2002/30682 ,  A61F2002/30683 ,  A61F2002/3082 ,  A61F2002/30937

摘要： Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, an artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a first component of the artificial joint prosthesis including a contact surface of the artificial joint prosthesis, the first component fabricated from at least one polymer and a plurality of magnetic particles; and a second component of the artificial joint prosthesis including at least one magnet configured to create a magnetic field within the artificial joint, the at least one magnet positioned to form a magnetic field directed to influence a location of debris including the magnetic particles in the joint to a position distinct from the bone-prosthesis interface in vivo.

摘要翻译： 描述了假肢人工关节，包括髋关节，膝关节和肩关节。 在一些实施例中，人造关节假体包括：人造关节假体的面向骨的表面，所述面向骨的表面构造成在体内面向骨假体界面; 所述人造关节假体的第一部件包括所述人造关节假体的接触表面，所述第一部件由至少一个聚合物和多个磁性颗粒制成; 以及所述人造关节假体的第二部件，所述第二部件包括构造成在所述人造关节内产生磁场的至少一个磁体，所述至少一个磁体定位成形成用于影响包括所述关节中的所述磁性颗粒的碎片位置的磁场 到与体内骨假体界面不同的位置。

公开(公告)号：US20140088720A1

公开(公告)日：2014-03-27

申请号：US13659020

申请日：2012-10-24

申请人： ELWHA LLC

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Clarence T. Tegreene

IPC分类号： A61F2/30 ,  A61F2/38 ,  A61F2/40 ,  A61F2/32

CPC分类号： A61F2/30 ,  A61F2/30742 ,  A61F2/32 ,  A61F2/38 ,  A61F2/40 ,  A61F2002/30079 ,  A61F2002/30087 ,  A61F2002/30558 ,  A61F2002/30673 ,  A61F2002/30682 ,  A61F2002/30683 ,  A61F2002/3082 ,  A61F2002/3092 ,  A61F2002/3429 ,  A61F2002/3631 ,  A61F2002/482

摘要： Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, an artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain non-physiological particles present within the synovial fluid.

摘要翻译： 描述了假肢人工关节，包括髋关节，膝关节和肩关节。 在一些实施例中，人造关节假体包括：人造关节假体的面向骨的表面，所述面向骨的表面构造成在体内面向骨假体界面; 人造关节假体的非接触表面，与人造关节假体的面向骨的表面相邻的非接触表面; 定位成邻近非接触表面定位的至少一个流体偏转结构，所述流体偏转结构被定位成使滑液在体内远离骨假体界面偏转; 附接到所述流体偏转结构的机构，所述机构可操作以移动所述流体偏转结构以将滑液体在体内远离所述骨假体界面引导; 以及至少一个颗粒保持结构，定位成接触滑液的定向流并被配置为保留存在于滑液内的非生理性颗粒。

公开(公告)号：US20140088719A1

公开(公告)日：2014-03-27

申请号：US13658982

申请日：2012-10-24

申请人： ELWHA LLC

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Clarence T. Tegreene

IPC分类号： A61F2/30 ,  A61F2/38 ,  A61F2/40 ,  A61F2/32

CPC分类号： A61F2/30 ,  A61F2/30742 ,  A61F2/32 ,  A61F2/38 ,  A61F2/40 ,  A61F2002/30079 ,  A61F2002/30087 ,  A61F2002/30558 ,  A61F2002/30673 ,  A61F2002/30682 ,  A61F2002/30683 ,  A61F2002/3082 ,  A61F2002/3092 ,  A61F2002/3429 ,  A61F2002/3631 ,  A61F2002/482

摘要： Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, a artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; and a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo.