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Patent Agency Ranking
公开(公告)号：US20210088503A1
公开(公告)日：2021-03-25
申请号：US17113527
申请日：2020-12-07
Applicant: General Electric Company
Inventor： Jessica Godin Karp , Xiaohui Chen , Kashan Ali Shaikh , Mengli Wang , Ralf Lenigk , Christine Lynne Surrette
Abstract: A device and/or methodology are described that include a mechanism for separating erythrocytes from other constituents of blood and for purifying leukocytes from blood. The separation and purification aspects may be provided in separate components or within the same component. The separation aspect assists in separating erythrocytes (red blood cells) from other cells in blood, such as by aggregation of the red blood cells. A suitable aggregation device or device component uses chambers with at least one small dimension (e.g., a microfluidic chip) to control the interaction of the blood with a solution containing a high molecular weight polymer (e.g., dextran) to achieve separation.
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公开(公告)号：US10830787B2
公开(公告)日：2020-11-10
申请号：US15968668
申请日：2018-05-01
Applicant: General Electric Company
Inventor： William Albert Challener , Mengli Wang
IPC: G01P15/093 , G01H9/00 , G02B26/02 , B81B7/02 , G01P15/08 , G01P15/097
Abstract: An accelerometer includes a membrane, an energy source producing a laser beam which is directed at the membrane causing it to vibrate, and a transparent cap disposed at one end of the energy source. The accelerometer includes a first controller for adjusting an output power of the energy source in a first feedback loop, a second controller for controlling the wavelength of the laser beam in a second feedback loop, and a detector sensing a reflected portion of the laser beam. An acceleration signal is based in part on the frequency of the reflected portion of the laser beam.
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公开(公告)号：US09080941B2
公开(公告)日：2015-07-14
申请号：US14277503
申请日：2014-05-14
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Kashan Ali Shaikh , Mengli Wang , Adriana Ines Larriera Moreno , Jessica Godin Karp , Christine Lynne Pitner
CPC classification number: G01N21/05 , B01L3/5027 , B01L3/502707 , B01L9/527 , B01L2200/027 , B01L2200/0689 , B01L2300/0816 , B01L2300/0822 , B01L2300/0867 , B01L2300/0877 , B01L2300/0887 , B01L2400/0655 , B32B37/0076 , B32B37/182 , B32B38/0008 , B32B2535/00 , C12Q1/6841 , G01N2021/058
Abstract: A microfluidic flow cell subassembly, which may be assembled into a flow cell having fluidic connections outside of the main substrate, is described for encapsulating a sample to allow for subsequent controlled delivery of reagents to the sample, such as multiplexed in situ biomarker staining and analysis. As configured, the subassembly comprises a substrate layer forms a flexible optically transparent lid which is capable of bending in either direction to alter the internal dimensions of the subassembly. Methods of use are also disclosed.
Abstract translation: 描述了可以组装成具有在主底物外部的流体连接的流动池的微流体流动池子组件，用于封装样品以允许随后控制的试剂递送到样品中，例如原位复合生物标记染色和分析 。 如所配置的，子组件包括基底层，形成柔性的光学透明盖，该盖能够沿任一方向弯曲以改变子组件的内部尺寸。 还公开了使用方法。
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公开(公告)号：US20150150462A1
公开(公告)日：2015-06-04
申请号：US14094814
申请日：2013-12-03
Applicant: General Electric Company
Inventor： Mengli Wang
IPC: A61B5/00
CPC classification number: A61B5/0095 , A61B5/742 , A61B5/748 , A61B2562/046
Abstract: A photoacoustic transducer assembly for imaging a subject of interest is presented. Furthermore, the photoacoustic transducer assembly includes a substrate. In addition, the photoacoustic transducer assembly includes a first plurality of source elements disposed on one or more sides of the substrate, wherein the first plurality of source elements is arranged along a periphery of the one or more sides of the substrate and configured to irradiate a region of interest in the subject of interest. Moreover, the photoacoustic transducer assembly also includes a plurality of detector elements disposed on the one or more sides of the substrate, wherein the plurality of detector elements is surrounded by the first plurality of source elements and configured to detect one or more signals generated by the region of interest in response to the irradiation.
Abstract translation: 提出了一种用于对感兴趣的对象成像的光声换能器组件。 此外，光声换能器组件包括基底。 另外，光声换能器组件包括设置在基板的一个或多个侧面上的第一多个源元件，其中第一多个源元件沿着基板的一个或多个边的周边布置，并被配置为照射 感兴趣的主题感兴趣的区域。 此外，光声换能器组件还包括设置在基板的一个或多个侧面上的多个检测器元件，其中多个检测器元件被第一多个源元件围绕并且被配置为检测由第一多个源元件产生的一个或多个信号 响应于照射的感兴趣区域。
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公开(公告)号：US20140248617A1
公开(公告)日：2014-09-04
申请号：US14277503
申请日：2014-05-14
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Kashan Ali Shaikh , Mengli Wang , Adriana Ines Larriera Moreno , Jessica Godin Karp , Christine Lynne Pitner
CPC classification number: G01N21/05 , B01L3/5027 , B01L3/502707 , B01L9/527 , B01L2200/027 , B01L2200/0689 , B01L2300/0816 , B01L2300/0822 , B01L2300/0867 , B01L2300/0877 , B01L2300/0887 , B01L2400/0655 , B32B37/0076 , B32B37/182 , B32B38/0008 , B32B2535/00 , C12Q1/6841 , G01N2021/058
Abstract: A microfluidic flow cell subassembly, which may be assembled into a flow cell having fluidic connections outside of the main substrate, is described for encapsulating a sample to allow for subsequent controlled delivery of reagents to the sample, such as multiplexed in situ biomarker staining and analysis. As configured, the subassembly comprises a substrate layer forms a flexible optically transparent lid which is capable of bending in either direction to alter the internal dimensions of the subassembly. Methods of use are also disclosed.
Abstract translation: 描述了可以组装成具有在主底物外部的流体连接的流动池的微流体流动池子组件，用于封装样品以允许随后控制的试剂递送到样品中，例如原位复合生物标记染色和分析 。 如所配置的，子组件包括基底层，形成柔性的光学透明盖，该盖能够沿任一方向弯曲以改变子组件的内部尺寸。 还公开了使用方法。
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