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48 条记录 (耗时 0.054 秒)

    Computer readable medium for performing sensor array based materials characterization
    16.
    发明授权
    Computer readable medium for performing sensor array based materials characterization 失效
    用于执行基于传感器阵列的材料表征的计算机可读介质

    公开(公告)号：US06668230B2

    公开(公告)日：2003-12-23

    申请号：US10315519

    申请日：2002-12-10

    申请人： Paul Mansky ,  James Bennett

    发明人： Paul Mansky ,  James Bennett

    IPC分类号： G01N3100

    CPC分类号： G01N25/005 ,  B01J19/0046 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00707 ,  B01J2219/00745 ,  B01J2219/00747 ,  C40B30/08 ,  C40B40/18 ,  G01N25/18 ,  G01N27/72

    摘要： A modular materials characterization apparatus includes a sensor array disposed on a substrate, with a standardized array and contact pad format; electronic test and measurement apparatus for sending electrical signals to and receiving electrical signals from the sensor array; an apparatus for making electrical contact to the sensors in the standardized array format; an apparatus for routing signals between one or more selected sensors and the electronic test and measurement apparatus and a computer including a computer readable having a computer program recorded therein for controlling the operator of the apparatus. The sensor array is preferably arranged in a standardized format used in combinatorial chemistry applications for rapid deposition of sample materials on the sensor array. The interconnection apparatus and sensor array and contact pad allow measurement of many different material properties by using substrates carrying different sensor types, with only minor modifications if any to the electronic test and measurement apparatus and test procedures. By using a sensor array that is separate from the electronic apparatus, and by including standardized contacting and signal routing apparatuses, the apparatus creates a modular “plug-and-play” system that eliminates the need for multiple materials characterization machines, and eliminates the need for application-specific active circuitry within the sensor arrays themselves. Further, the modular sensor array system can characterize large numbers of material samples rapidly, on the order of at least 50 samples per hour, reducing the time needed for screening of materials libraries.

    摘要翻译： 模块化材料表征装置包括设置在基板上的传感器阵列，具有标准化的阵列和接触垫格式; 电子测试和测量装置，用于向传感器阵列发送电信号并接收电信号; 用于以标准阵列格式与传感器电接触的装置; 用于在一个或多个选择的传感器和电子测试和测量装置之间路由信号的装置和包括计算机可读的计算机，其中记录有计算机程序以控制装置的操作者。 传感器阵列优选地以用于组合化学应用中的标准化格式布置，用于将样品材料快速沉积在传感器阵列上。 互连装置和传感器阵列和接触垫允许通过使用携带不同传感器类型的基板来测量许多不同的材料性质，只要对电子测试和测量装置和测试程序进行微小的修改即可。 通过使用与电子设备分离的传感器阵列，并且通过包括标准化的接触和信号路由设备，该设备创建了模块化的“即插即用”系统，其消除了对多种材料表征机器的需要，并且消除了需要 用于传感器阵列本身内的特定于应用的有源电路。 此外，模块化传感器阵列系统可以快速表征大量材料样品，每小时至少50个样品量级，减少了材料库筛选所需的时间。

    Sensor array-based system and method for rapid materials characterization
    17.
    发明授权
    Sensor array-based system and method for rapid materials characterization 失效

    公开(公告)号：US06535824B1

    公开(公告)日：2003-03-18

    申请号：US09458398

    申请日：1999-12-10

    申请人： Paul Mansky ,  James Bennett

    发明人： Paul Mansky ,  James Bennett

    IPC分类号： G01N3100

    CPC分类号： G01N25/005 ,  B01J19/0046 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00707 ,  B01J2219/00745 ,  B01J2219/00747 ,  C40B30/08 ,  C40B40/18 ,  G01N25/18 ,  G01N27/72

    摘要： A modular materials characterization apparatus includes a sensor array disposed on a substrate, with a standardized array and contact pad format; electronic test and measurement apparatus for sending electrical signals to and receiving electrical signals from the sensor array; an apparatus for making electrical contact to the sensors in the standardized array format; an apparatus for routing signals between one or more selected sensors and the electronic test and measurement apparatus and a computer including a computer readable having a computer program recorded therein for controlling the operator of the apparatus. The sensor array is preferably arranged in a standardized format used in combinatorial chemistry applications for rapid deposition of sample materials on the sensor array. The interconnection apparatus and sensor array and contact pad allow measurement of many different material properties by using substrates carrying different sensor types, with only minor modifications if any to the electronic test and measurement apparatus and test procedures. By using a sensor array that is separate from the electronic apparatus, and by including standardized contacting and signal routing apparatuses, the apparatus creates a modular “plug-and-play” system that eliminates the need for multiple materials characterization machines, and eliminates the need for application-specific active circuitry within the sensor arrays themselves. Further, the modular sensor array system can characterize large numbers of material samples rapidly, on the order of at least 50 samples per hour, reducing the time needed for screening of materials libraries.

    Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
    19.
    发明授权
    Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom 有权
    制备具有交联壳和由其产生的核 - 壳复合材料的核 - 壳复合材料的方法

    公开(公告)号：US08586097B2

    公开(公告)日：2013-11-19

    申请号：US12088611

    申请日：2006-10-02

    申请人： Futian Liu ,  Han-Ting Chang ,  Dominique Charmot ,  Eric Connor ,  Paul Mansky ,  Mingjun Liu

    发明人： Futian Liu ,  Han-Ting Chang ,  Dominique Charmot ,  Eric Connor ,  Paul Mansky ,  Mingjun Liu

    IPC分类号： A61K9/14 ,  A61K9/58

    CPC分类号： A61K31/795 ,  A61K9/5026 ,  A61K9/5031 ,  A61K9/5036 ,  A61K9/5042

    摘要： The present invention provides methods and compositions for the treatment of ion imbalances using core-shell composites and compositions comprising such core-shell composites. In particular, the invention provides core-shell particles and compositions comprising potassium binding polymers, and core-shell particles and compositions comprising sodium binding polymers, and in each case, pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are also disclosed. The compositions and methods of the invention offer improved approaches for treatment of hyperkalemia and other indications related to potassium ion homeostasis, and for treatment of hypertension and other indicates related to sodium ion homeostasis.

    摘要翻译： 本发明提供了使用核 - 壳复合材料和包含这种核 - 壳复合材料的组合物来处理离子不平衡的方法和组合物。 特别地，本发明提供了核 - 壳颗粒和包含钾结合聚合物的组合物，以及包含钠结合聚合物的核 - 壳颗粒和组合物，并且在每种情况下都是其药物组合物。 还公开了用于治疗和/或预防益处的聚合物和药物组合物的使用方法。 本发明的组合物和方法提供治疗高钾血症和与钾离子稳态相关的其它适应症的改进方法，以及用于治疗与钠离子稳态有关的高血压和其它指征。