Nanocrystals
    11.
    发明申请
    Nanocrystals 有权
    纳米晶体

    公开(公告)号:US20050112376A1

    公开(公告)日:2005-05-26

    申请号:US10952701

    申请日:2004-09-29

    申请人: Imad Naasani

    发明人: Imad Naasani

    摘要: Provided herein are compositions of functionalized, fluorescent nanocrystals comprising fluorescent nanocrystals coated with an imidazole-containing compound; compositions of functionalized, fluorescent nanocrystals comprising fluorescent nanocrystals coated with an imidazole-containing compound and cross-linked with a phosphine cross-linking compound; compositions of functionalized fluorescent nanocrystals operably bound to molecular probe; a process of making functionalized, fluorescent nanocrystals; and a process of using functionalized, fluorescent nanocrystals in a detection system.

    摘要翻译: 本文提供了包含用含咪唑的化合物涂覆的荧光纳米晶体的官能化荧光纳米晶体的组合物; 官能化荧光纳米晶体的组成包括用含咪唑的化合物涂覆并与膦交联化合物交联的荧光纳米晶体; 可操作地结合分子探针的官能化荧光纳米晶体的组成; 制备官能化荧光纳米晶体的方法; 以及在检测系统中使用官能化的荧光纳米晶体的过程。

    Functionalized Fluorescent Nanocrystal Compositions and Methods for Their Preparation
    14.
    发明申请
    Functionalized Fluorescent Nanocrystal Compositions and Methods for Their Preparation 有权
    功能化荧光纳米晶体组合物及其制备方法

    公开(公告)号:US20100291702A1

    公开(公告)日:2010-11-18

    申请号:US11685343

    申请日:2007-03-13

    申请人: Imad Naasani

    发明人: Imad Naasani

    IPC分类号: G01N21/76

    摘要: The present invention provides for functionalized fluorescent nanocrystal compositions and methods for making these compositions. The compositions are fluorescent nanocrystals coated with at least one material. The coating material has chemical compounds or ligands with functional groups or moieties with conjugated electrons and moieties for imparting solubility to coated fluorescent nanocrystals in aqueous solutions. The coating material provides for functionalized fluorescent nanocrystal compositions which are water soluble, chemically stable, and emit light with a high quantum yield and/or luminescence efficiency when excited with light. The coating material may also have chemical compounds or ligands with moieties for bonding to target molecules and cells as well as moieties for cross-linking the coating. In the presence of reagents suitable for reacting to form capping layers, the compounds in the coating may form a capping layer on the fluorescent nanocrystal with the coating compounds operably bonded to the capping layer.

    摘要翻译: 本发明提供了功能化的荧光纳米晶体组合物和制备这些组合物的方法。 组合物是涂覆有至少一种材料的荧光纳米晶体。 涂层材料具有具有带有共轭电子和部分的官能团或部分的化学化合物或配体,以在水溶液中赋予涂覆的荧光纳米晶体的溶解性。 涂层材料提供功能化的荧光纳米晶体组合物,其水溶性,化学稳定性,并且当用光激发时具有高量子产率和/或发光效率的光。 涂层材料还可以具有化学化合物或具有用于键合到靶分子和细胞的部分的配体以及用于交联涂层的部分。 在适于反应形成覆盖层的试剂存在下,涂层中的化合物可以在荧光纳米晶体上形成覆盖层,其中涂层化合物可操作地结合到覆盖层上。

    Functionalized fluorescent nanocrystals, and methods for their preparation and use

    公开(公告)号:US20080213919A1

    公开(公告)日:2008-09-04

    申请号:US12041589

    申请日:2008-03-03

    申请人: Imad Naasani

    发明人: Imad Naasani

    摘要: Functionalized fluorescent nanocrystal compositions and methods for making and using these compositions are disclosed. The compositions are fluorescent nanocrystals coated with at least one material. The coating material has chemical compounds or ligands with functional groups or moieties with conjugated electrons and moieties for imparting solubility to coated fluorescent nanocrystals in aqueous solutions. The coating material provides for functionalized fluorescent nanocrystal compositions which are water soluble, chemically stable, and emit light with a high quantum yield and/or luminescence efficiency when excited with light. The coating material may also have chemical compounds or ligands with moieties for bonding to target molecules and cells as well as moieties for cross-linking the coating. In the presence of reagents suitable for reacting to form capping layers, the compounds in the coating may form a capping layer on the fluorescent nanocrystal with the coating compounds operably bonded to the capping layer.

    Highly luminescent functionalized semiconductor nanocrystals for biological and physical applications
    16.
    发明授权
    Highly luminescent functionalized semiconductor nanocrystals for biological and physical applications 有权
    用于生物和物理应用的高发光官能化半导体纳米晶体

    公开(公告)号:US07214428B2

    公开(公告)日:2007-05-08

    申请号:US10410108

    申请日:2003-04-09

    申请人: Imad Naasani

    发明人: Imad Naasani

    IPC分类号: B32B5/16

    摘要: The present invention provides for detection apparatus with functionalized fluorescent nanocrystal compositions and methods for making and using these compositions in biological detection applications, material separations, and in the production of biosensors. The compositions are fluorescent nanocrystals coated with at least one coating material comprising ligands with functional groups or moieties with conjugated electrons and moieties for imparting solubility to fluorescent nanocrystals in aqueous solutions. The coating material provides for functionalized fluorescent nanocrystal compositions which are water soluble, chemically stable, and emit light with a high quantum yield and/or luminescence efficiency when excited with light. The coating material may also have chemical compounds or ligands with moieties for bonding to target molecules and cells as well as moieties for cross-linking the coating.

    摘要翻译: 本发明提供了具有官能化荧光纳米晶体组合物的检测装置以及用于在生物检测应用,材料分离和生物传感器生产中制备和使用这些组合物的方法。 组合物是涂覆有至少一种涂层材料的荧光纳米晶体,所述涂层材料包含具有带有共轭电子的官能团或部分的配体和用于在水溶液中赋予荧光纳米晶体的溶解度的部分。 涂层材料提供功能化的荧光纳米晶体组合物,其水溶性,化学稳定性,并且当用光激发时具有高量子产率和/或发光效率的光。 涂层材料还可以具有化学化合物或具有用于键合到靶分子和细胞的部分的配体以及用于交联涂层的部分。

    Nanocrystals
    17.
    发明授权
    Nanocrystals 有权
    纳米晶体

    公开(公告)号:US07198847B2

    公开(公告)日:2007-04-03

    申请号:US10952701

    申请日:2004-09-29

    申请人: Imad Naasani

    发明人: Imad Naasani

    IPC分类号: B32B5/16

    摘要: Provided herein are compositions of functionalized, fluorescent nanocrystals comprising fluorescent nanocrystals coated with an imidazole-containing compound; compositions of functionalized, fluorescent nanocrystals comprising fluorescent nanocrystals coated with an imidazole-containing compound and cross-linked with a phosphine cross-linking compound; compositions of functionalized fluorescent nanocrystals operably bound to molecular probe; a process of making functionalized, fluorescent nanocrystals; and a process of using functionalized, fluorescent nanocrystals in a detection system.

    摘要翻译: 本文提供了包含用含咪唑的化合物涂覆的荧光纳米晶体的官能化荧光纳米晶体的组合物; 官能化荧光纳米晶体的组成包括用含咪唑的化合物涂覆并与膦交联化合物交联的荧光纳米晶体; 可操作地结合分子探针的官能化荧光纳米晶体的组成; 制备官能化荧光纳米晶体的方法; 以及在检测系统中使用官能化的荧光纳米晶体的过程。

    Nanocrystals
    18.
    发明授权

    公开(公告)号:US06955855B2

    公开(公告)日:2005-10-18

    申请号:US10245082

    申请日:2002-09-17

    申请人: Imad Naasani

    发明人: Imad Naasani

    摘要: Provided herein are compositions of functionalized, fluorescent nanocrystals comprising fluorescent nanocrystals coated with an imidazole-containing compound; compositions of functionalized, fluorescent nanocrystals comprising fluorescent nanocrystals coated with an imidazole-containing compound and cross-linked with a phosphine cross-linking compound; compositions of functionalized fluorescent nanocrystals operably bound to molecular probe; a process of making functionalized, fluorescent nanocrystals; and a process of using functionalized, fluorescent nanocrystals in a detection system.

    Functionalized fluorescent nanocrystal compositions and methods for their preparation
    19.
    发明授权
    Functionalized fluorescent nanocrystal compositions and methods for their preparation 有权
    功能化荧光纳米晶体组合物及其制备方法

    公开(公告)号:US08283179B2

    公开(公告)日:2012-10-09

    申请号:US11685343

    申请日:2007-03-13

    申请人: Imad Naasani

    发明人: Imad Naasani

    IPC分类号: G01N21/76

    摘要: The present invention provides for functionalized fluorescent nanocrystal compositions and methods for making these compositions. The compositions are fluorescent nanocrystals coated with at least one material. The coating material has chemical compounds or ligands with functional groups or moieties with conjugated electrons and moieties for imparting solubility to coated fluorescent nanocrystals in aqueous solutions. The coating material provides for functionalized fluorescent nanocrystal compositions which are water soluble, chemically stable, and emit light with a high quantum yield and/or luminescence efficiency when excited with light. The coating material may also have chemical compounds or ligands with moieties for bonding to target molecules and cells as well as moieties for cross-linking the coating. In the presence of reagents suitable for reacting to form capping layers, the compounds in the coating may form a capping layer on the fluorescent nanocrystal with the coating compounds operably bonded to the capping layer.

    摘要翻译: 本发明提供了功能化的荧光纳米晶体组合物和制备这些组合物的方法。 组合物是涂覆有至少一种材料的荧光纳米晶体。 涂层材料具有具有带有共轭电子和部分的官能团或部分的化学化合物或配体,以在水溶液中赋予涂覆的荧光纳米晶体的溶解性。 涂层材料提供功能化的荧光纳米晶体组合物,其水溶性,化学稳定性,并且当用光激发时具有高量子产率和/或发光效率的光。 涂层材料还可以具有化学化合物或具有用于键合到靶分子和细胞的部分的配体以及用于交联涂层的部分。 在适于反应形成覆盖层的试剂存在下,涂层中的化合物可以在荧光纳米晶体上形成覆盖层,其中涂层化合物可操作地结合到覆盖层上。