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公开(公告)号：US08232320B2
公开(公告)日：2012-07-31
申请号：US11928427
申请日：2007-10-30
申请人： James R. Baker, Jr. , Tarek Hamouda , Amy Shih , Andrzej Myc
发明人： James R. Baker, Jr. , Tarek Hamouda , Amy Shih , Andrzej Myc
IPC分类号： A01N33/12 , A61K31/14 , A61K31/235 , A61K31/74 , A61K9/14
CPC分类号： A61K31/522 , A61K8/062 , A61K8/068 , A61K9/1075 , A61K31/14 , A61K45/06 , A61K2800/413 , A61Q17/005 , B82Y5/00 , Y02A50/393 , Y02A50/402 , Y02A50/463 , Y02A50/469 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/481 , Y10S514/937 , Y10S514/938 , A61K2300/00
摘要： The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
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公开(公告)号：US20090143477A1
公开(公告)日：2009-06-04
申请号：US11928447
申请日：2007-10-30
申请人： James R. Baker, JR. , Tarek Hamouda , Amy Shih , Andrzej Myc
发明人： James R. Baker, JR. , Tarek Hamouda , Amy Shih , Andrzej Myc
CPC分类号： A61K31/522 , A61K8/062 , A61K8/068 , A61K9/1075 , A61K31/14 , A61K45/06 , A61K2800/413 , A61Q17/005 , B82Y5/00 , Y02A50/393 , Y02A50/402 , Y02A50/463 , Y02A50/469 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/481 , Y10S514/937 , Y10S514/938 , A61K2300/00
摘要： The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
摘要翻译： 本发明涉及用于降低与各种致病生物体和病毒有关的感染性，发病率和死亡率的组合物和方法。 本发明还涉及用于对由致病菌和病毒定殖或以其它方式感染的区域进行净化的方法和组合物。 此外，本发明涉及用于降低食品中病原生物体的感染性的方法和组合物。
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公开(公告)号：US06559189B2
公开(公告)日：2003-05-06
申请号：US09891086
申请日：2001-06-25
申请人： James R. Baker, Jr. , Tarek Hamouda , Amy Shih , Andrzej Myc
发明人： James R. Baker, Jr. , Tarek Hamouda , Amy Shih , Andrzej Myc
IPC分类号： A61K3114
CPC分类号： A61K8/062 , A61K8/06 , A61K9/1075 , A61K31/14 , A61K45/06 , A61K2800/21 , A61K2800/413 , A61Q5/006 , A61Q11/00 , A61Q15/00 , A61Q17/005 , B82Y5/00 , A61K2300/00
摘要： The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
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公开(公告)号：US09492525B2
公开(公告)日：2016-11-15
申请号：US13543493
申请日：2012-07-06
IPC分类号： A61K9/107 , A61P37/04 , A61K39/155 , A61K39/12 , C07K16/10 , C12N7/00 , A61K9/00 , A61K9/06 , A61K9/127 , A61K9/51 , A61K31/716 , A61K31/722 , A61K39/00
CPC分类号： A61K39/12 , A61K9/0019 , A61K9/06 , A61K9/1075 , A61K9/1271 , A61K9/5115 , A61K31/716 , A61K31/722 , A61K47/26 , A61K47/38 , A61K47/44 , A61K2039/5252 , A61K2039/543 , A61K2039/55555 , A61K2039/55566 , A61K2039/55583 , C07K16/1027 , C07K2317/33 , C07K2317/76 , C12N7/00 , C12N2760/18521 , C12N2760/18522 , C12N2760/18534 , A61K2300/00
摘要： The present invention relates to RSV vaccines and methods for inducing an immune response to RSV in a subject comprising administering an RSV vaccine.
摘要翻译： 本发明涉及用于在受试者中诱导对RSV的免疫应答的RSV疫苗和方法，包括施用RSV疫苗。
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公开(公告)号：US10206996B2
公开(公告)日：2019-02-19
申请号：US13591775
申请日：2012-08-22
申请人： Ali I. Fattom , Jakub Simon , James R. Baker, Jr. , Tarek Hamouda , Vira Bitko
发明人： Ali I. Fattom , Jakub Simon , James R. Baker, Jr. , Tarek Hamouda , Vira Bitko
IPC分类号： A61K39/00 , A61K39/245 , A61K39/39 , A61K9/107 , A61K39/12
摘要： The present application relates to the field of human immunology, in particular, a herpes simplex virus (HSV) vaccine. The subunit vaccine composition comprises isolated surface glycoproteins from herpes simplex viruses, fusion proteins or fragments thereof mixed in varied combination with a nanoemulsion, which is a potent immune enhancer.
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公开(公告)号：US09561271B2
公开(公告)日：2017-02-07
申请号：US13608317
申请日：2012-09-10
申请人： Ali I. Fattom , Tarek Hamouda , Vira Bitko , James R. Baker, Jr.
发明人： Ali I. Fattom , Tarek Hamouda , Vira Bitko , James R. Baker, Jr.
IPC分类号： A61K39/155 , A61K9/107 , A61K47/10 , A61K47/18 , A61K47/26 , A61K47/44 , A61K39/12 , A61K39/00
CPC分类号： A61K39/155 , A61K9/1075 , A61K39/12 , A61K47/10 , A61K47/186 , A61K47/26 , A61K47/44 , A61K2039/5252 , A61K2039/543 , A61K2039/55555 , A61K2039/55566 , C12N2760/18034
摘要： The present application relates to the field of immunology, in particular, a vaccine composition of respiratory syncytial virus (RSV) surface proteins, Fusion (F) and Glycoprotein (G) proteins subunit vaccine preferentially mixed with the immune cell targeting and enhancer, nanoemulsion to induce a protective immune response and avoid vaccine-induce disease enhancement.
摘要翻译： 本申请涉及免疫学领域，特别是呼吸道合胞病毒（RSV）表面蛋白，融合（F）和糖蛋白（G）蛋白亚基疫苗的疫苗组合物优先与免疫细胞靶向和增强子混合，纳米乳剂 诱导保护性免疫应答，并避免疫苗诱导疾病增强。
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公开(公告)号：US09144606B2
公开(公告)日：2015-09-29
申请号：US12427517
申请日：2009-04-21
IPC分类号： A61K39/145 , C07K14/005 , C12N7/00 , A61K9/107 , A61K39/00 , A61K39/12
CPC分类号： A61K39/145 , A61K9/0014 , A61K9/0043 , A61K9/1075 , A61K39/00 , A61K39/12 , A61K39/39 , A61K2039/5252 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55566 , A61K2039/58 , A61K2039/70 , C07K14/005 , C12N7/00 , C12N2760/16134 , C12N2760/16171 , C12N2760/16234 , C12N2760/16271
摘要： The present invention relates to methods for inducing an immune response to influenza in a subject comprising administering a nanoemulsion vaccine composition comprising an influenza immunogen or protein.
摘要翻译： 本发明涉及在受试者中诱导针对流感的免疫应答的方法，包括施用包含流感免疫原或蛋白质的纳米乳剂疫苗组合物。
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18.发明申请COMPOSITIONS FOR INACTIVATING PATHOGENIC MICROORGANISMS, METHODS OF MAKING THE COMPOSITIONS, AND METHODS OF USE THEREOF 有权用于灭活病原微生物的组合物，制备组合物的方法及其使用方法公开(公告)号：US20120171249A1
公开(公告)日：2012-07-05
申请号：US11930535
申请日：2007-10-31
IPC分类号： A61K9/00 , A61K47/44 , A61P31/22 , A61P31/12 , A61P31/00 , A61P31/04 , A61K31/522 , A61P31/10 , B82Y5/00
CPC分类号： A01N25/04 , A01N25/02 , A61K9/0014 , A61K9/0034 , A61K9/0043 , A61K9/0073 , A61K9/1075 , A61K31/7048 , A61K39/00 , A61K2039/5252 , C12N7/00 , C12N2760/16163
摘要： Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.
摘要翻译： 描述了显示出微生物的广谱灭活或预防疾病的低毒性的纳米乳剂组合物。 纳米乳剂含有水相，包含油和有机溶剂的油相和一种或多种表面活性剂。 还提供了制备纳米乳剂和灭活病原微生物的方法。
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公开(公告)号：US20130011443A1
公开(公告)日：2013-01-10
申请号：US13543493
申请日：2012-07-06
IPC分类号： A61K9/107 , A61P37/04 , A61K39/155 , B82Y5/00
CPC分类号： A61K39/12 , A61K9/0019 , A61K9/06 , A61K9/1075 , A61K9/1271 , A61K9/5115 , A61K31/716 , A61K31/722 , A61K47/26 , A61K47/38 , A61K47/44 , A61K2039/5252 , A61K2039/543 , A61K2039/55555 , A61K2039/55566 , A61K2039/55583 , C07K16/1027 , C07K2317/33 , C07K2317/76 , C12N7/00 , C12N2760/18521 , C12N2760/18522 , C12N2760/18534 , A61K2300/00
摘要： The present invention relates to RSV vaccines and methods for inducing an immune response to RSV in a subject comprising administering an RSV vaccine.
摘要翻译： 本发明涉及用于在受试者中诱导对RSV的免疫应答的RSV疫苗和方法，包括施用RSV疫苗。
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公开(公告)号：US20120219602A1
公开(公告)日：2012-08-30
申请号：US13407695
申请日：2012-02-28
IPC分类号： A61K9/107 , A61P31/22 , A61K31/20 , A61K31/4164 , B82Y5/00
CPC分类号： A61K9/1075 , A61K9/0014
摘要： The present invention relates to methods for treating, killing, and/or inhibiting the growth of Herpes viruses in human subjects comprising topically administering to a human subject in need thereof a nanoemulsion composition having antiviral properties.
摘要翻译： 本发明涉及用于治疗，杀死和/或抑制人类受试者中疱疹病毒生长的方法，包括向有需要的人类受试者局部施用具有抗病毒性质的纳米乳剂组合物。
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