公开(公告)号：US20170161429A1

公开(公告)日：2017-06-08

申请号：US15350444

申请日：2016-11-14

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jacob Freudenthal ,  Jeffrey Marks ,  Francis Cheng ,  Thomas Wessel

IPC: G06K9/00

CPC classification number: G06T7/0012 ,  G06T5/008 ,  G06T5/50 ,  G06T2207/10024 ,  G06T2207/10064 ,  G06T2207/10144 ,  G06T2207/20021 ,  G06T2207/20216 ,  G06T2207/30072

Abstract: A method for calibrating a biological instrument is provided. The method comprises the steps of acquiring an image of at least one biological sample array, determining a first region of interest within the image, wherein the first region of interest comprises a first plurality of locations on the at least one biological array; and identifying within the first region of interest, a plurality of image elements associated with each of the first plurality of locations on the at least one biological array.

公开(公告)号：US20160228876A1

公开(公告)日：2016-08-11

申请号：US15017393

申请日：2016-02-05

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Yong Chu ,  Jeffrey Marks ,  Jacob Freudenthal ,  Mingsong Chen ,  Tiong Han Toh ,  Mauro Aguanno ,  Lik Seng Lau ,  Lian Seng Loh ,  Kok Siong Teo ,  Zeng Wei Chu ,  Xin Mathers ,  Michael Uy ,  Huei Yeo ,  Kuan Moon Boo ,  Way Xuang Lee ,  Chin Yong Koo ,  Wei Fuh Teo ,  Soo Yong Lau ,  Hon Siu Shin ,  Zeqi Tan ,  Thomas Wessel ,  Woo David

IPC: B01L7/00 ,  C12Q1/68 ,  G01N21/64

CPC classification number: B01L7/52 ,  B01L2200/145 ,  B01L2300/18 ,  B01L2300/1822 ,  C12Q1/6806 ,  G01N21/274 ,  G01N21/6452 ,  G01N21/6486 ,  G01N35/026 ,  G01N2021/6439 ,  G01N2035/00316 ,  G01N2035/00366 ,  G01N2201/061 ,  G01N2201/12

Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.

Abstract translation: 提供生物分析系统。 该系统包括样品块组件。 样品块组件包括被配置为容纳样品架的样品块，样品保持器被配置为接收多个样品。 该系统还包括配置成使多个样品循环通过一系列温度的控制系统。 所述系统还包括自动盘，其包括滑动组件，所述托盘被配置为可将所述样品块组件从关闭位置可逆地滑动至打开位置，以允许使用者接近所述多个样品保持器。

公开(公告)号：US09267170B2

公开(公告)日：2016-02-23

申请号：US14348881

申请日：2012-09-28

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Ronald Danehy ,  Gary Lim ,  Jacob Freudenthal

IPC: C12Q1/68 ,  C12M1/32 ,  C12M1/00 ,  B01L3/00

CPC classification number: C12Q1/6806 ,  B01L3/50851 ,  B01L3/50855 ,  B01L3/50857 ,  B01L2200/026 ,  B01L2200/0642 ,  B01L2200/0684 ,  B01L2200/142 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/0858 ,  B01L2300/0893 ,  B01L2300/161 ,  C12M23/12 ,  C12M23/38

Abstract: A case for containing a plurality of biological samples contains a base, a substrate and a cover. The substrate is attached to the base and comprises a plurality of reaction regions configured to receive one or more biological samples. The cover comprises an inner surface and is configured to be attached to the base such that the base and cover together provide a cavity containing the substrate. The inner surface includes a central area and a recessed area disposed about the central area. The central area is configured to cover the reaction regions, while the recessed area is offset from the central area in a direction normal to the inner surface.

Abstract translation: 用于容纳多个生物样品的壳体包含基底，基底和盖。 底物附着到基底上，并且包括被配置成接收一个或多个生物样品的多个反应区域。 盖子包括内表面，并且被构造成附接到基座，使得基座和盖子一起提供容纳基底的空腔。 内表面包括中心区域和围绕中心区域设置的凹陷区域。 中心区域构造成覆盖反应区域，而凹陷区域在垂直于内表面的方向上偏离中心区域。