公开(公告)号：US09827090B2

公开(公告)日：2017-11-28

申请号：US13692577

申请日：2012-12-03

Applicant: Medtronic, Inc.

Inventor： Alexander J. Hill ,  Cynthia Clague ,  Carol E. Eberhardt ,  Ana Menk ,  Mark J. Capps ,  Billie Millwee ,  Janice Lynn Shay ,  Debra Taitague ,  Joseph C. Morrow ,  Jerald Redmond

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/24 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/2454 ,  A61F2/2457 ,  A61F2/2463 ,  A61F2/2487 ,  A61F2210/0014 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/001 ,  A61F2230/0045 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0076 ,  A61F2230/008 ,  A61F2250/0039

Abstract: A stented valve having at least one leaflet made of pericardium or other material having a relatively thin profile at the annulus. The leaflets are attached via chords to a stent frame, where the chords are positioned to mimic the native valve anatomy and functionality. In particular, the valves of one exemplary embodiment of the invention are sized to replace a mitral valve and therefore the chords are arranged to prevent prolapse of the leaflets into the atrium. The stented valve has a relatively short height at its annulus due to the positioning of the chords. In addition, the stented valve is capable of being crimped to a small enough size that it can be delivered to the implantation site via transcatheter delivery systems and methods.

公开(公告)号：US20140221823A1

公开(公告)日：2014-08-07

申请号：US14174268

申请日：2014-02-06

Applicant: Medtronic, Inc.

Inventor： James R. Keogh ,  Timothy R. Ryan ,  Carol E. Eberhardt ,  Mark T. Stewart ,  James R. Skarda ,  Timothy G. Laske ,  Alexander J. Hill ,  Jack D. Lemmon ,  David E. Francischelli

IPC: A61F2/24 ,  A61B19/00 ,  A61B5/107 ,  A61B5/00

CPC classification number: A61F2/2496 ,  A61B5/0044 ,  A61B5/1076 ,  A61B5/6853 ,  A61B8/445 ,  A61B18/1442 ,  A61B34/20 ,  A61B90/37 ,  A61B90/39 ,  A61B2017/00243 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2034/2051 ,  A61B2034/2063 ,  A61B2090/378 ,  A61B2090/397 ,  A61F2/2433 ,  A61F2210/009 ,  A61F2250/0096 ,  A61N7/02

Abstract: A method for valve replacement or valve repair is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding a valve replacement delivery member or a valve repair delivery member within the patient while tracking the position of the delivery member in the patient, positioning the valve replacement member or valve repair member in a desired position to place a valve or repair valve and removing the delivery member from the patient. In one aspect, a method and device are provided that involve imaging a native root using an interoperative technique, then introducing a device that is easily visualized in a chosen imaging modality.

Abstract translation: 公开了一种用于瓣膜置换或瓣膜修复的方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，引导患者内的瓣膜置换递送构件或瓣膜修复递送构件，同时跟踪患者的位置 将所述阀更换构件或阀修复构件定位在期望位置以放置阀或修复阀并从所述患者移除​​所述递送构件。 在一个方面，提供了一种方法和装置，其涉及使用交互技术对本地根进行成像，然后引入在选择的成像模式中容易可视化的装置。

公开(公告)号：US10548723B2

公开(公告)日：2020-02-04

申请号：US15793639

申请日：2017-10-25

Applicant: Medtronic, Inc.

Inventor： Alexander J. Hill ,  Cynthia Clague ,  Carol E. Eberhardt ,  Ana Menk ,  Mark J. Capps ,  Billie Millwee ,  Janice Lynn Shay ,  Debra Taitague ,  Joseph C. Morrow ,  Jerald Redmond

IPC: A61F2/24

Abstract: A stented valve having at least one leaflet made of pericardium or other material having a relatively thin profile at the annulus. The leaflets are attached via chords to a stent frame, where the chords are positioned to mimic the native valve anatomy and functionality. In particular, the valves of one exemplary embodiment of the invention are sized to replace a mitral valve and therefore the chords are arranged to prevent prolapse of the leaflets into the atrium. The stented valve has a relatively short height at its annulus due to the positioning of the chords. In addition, the stented valve is capable of being crimped to a small enough size that it can be delivered to the implantation site via transcatheter delivery systems and methods.

公开(公告)号：US10335280B2

公开(公告)日：2019-07-02

申请号：US15098494

申请日：2016-04-14

Applicant: Medtronic, Inc.

Inventor： James R. Keogh ,  Timothy R. Ryan ,  Carol E. Eberhardt ,  Mark T. Stewart ,  James R. Skarda ,  Timothy G. Laske ,  Alexander J. Hill ,  Jack D. Lemmon ,  David E. Francischelli

IPC: A61N7/02 ,  A61F2/24 ,  A61B5/00 ,  A61B5/107 ,  A61B8/00 ,  A61B34/20 ,  A61B90/00 ,  A61B18/14 ,  A61B17/00 ,  A61B18/00

Abstract: A method for treating a human patient includes emitting ultrasound energy from an ultrasound transducer positioned remotely from target tissue of the patient. The ultrasound transducer is positioned at a desired location relative to the patient and target tissue using location and imaging techniques. The method further includes focusing the ultrasound energy such that one or more focal points are directed to the target tissue of the patient and ablating the target tissue at each focal point. The target tissue is ablated via the focused ultrasound energy without ablating non-target tissue through which the ultrasound energy passes between the ultrasound transducer and the one or more focal points.

公开(公告)号：US10130473B2

公开(公告)日：2018-11-20

申请号：US15712575

申请日：2017-09-22

Applicant: Medtronic, Inc.

Inventor： Timothy R. Ryan ,  Alexander J. Hill ,  Jason L. Quill ,  Jerald L. Redmond ,  Stephen Kuehn ,  Eugene Grossi ,  Aubrey Galloway ,  Hugo Vanermen ,  Rudiger Lange

IPC: A61F2/24 ,  A61B17/06

Abstract: Annuloplasty device for implantation adjacent an annulus of a tricuspid valve, the annulus comprising anterior, posterior and septal aspects adjacent anterior, posterior and septal leaflets, respectively, of the tricuspid valve, the device comprising: a ring body comprising: an anterior portion, a posterior portion and a septal portion shaped to conform to, and for implantation adjacent, the anterior, posterior and septal aspects of the annulus, respectively; and first and second end portions that are more flexible than a remainder of the ring body to provide a gradual transition from the remainder of the ring body to tissue of the tricuspid valve annulus; wherein the ring body is curvilinear, with substantially no flat portions, and forming a shape. Related devices, kits and sizer devices.

公开(公告)号：US20150018940A1

公开(公告)日：2015-01-15

申请号：US14328050

申请日：2014-07-10

Applicant: Medtronic, Inc.

Inventor： Jason Quill ,  Cynthia Clague ,  Michael Green ,  Alexander J. Hill ,  Ana Menk ,  Paul Rothstein ,  Georg Bortlein

IPC: A61F2/24

CPC classification number: A61F2/2442 ,  A61B17/068 ,  A61B2017/00243 ,  A61B2017/00331 ,  A61B2017/00349 ,  A61B2017/00783 ,  A61B2017/0649 ,  A61F2/2412 ,  A61F2002/249 ,  A61F2230/0091

Abstract: Systems and methods for modifying a heart valve annulus in a minimally invasive surgical procedure. A helical anchor is provided, having a memory set to a coiled shape or state. The helical anchor is further configured to self-revert from a substantially straight state to the coiled state. The helical anchor is loaded within a needle that constrains the helical anchor to the substantially straight state. The needle is delivered to the valve annulus and inserted into tissue of the annulus. The helical anchor is then deployed from the needle (e.g., the needle is retracted from over the helical anchor). Once deployed, the helical anchor self-transitions toward the coiled shape, cinching engaged tissue of the valve annulus.

Abstract translation: 用于在微创外科手术中改变心脏瓣膜环的系统和方法。 提供螺旋锚，其具有设置成盘绕形状或状态的存储器。 螺旋锚还被构造成从基本上直的状态自动恢复到卷绕状态。 螺旋锚被装载在针内，将螺旋锚定器约束到基本上直的状态。 针被递送到瓣膜环并插入环的组织中。 然后螺旋锚从针展开（例如，针从螺旋锚上方缩回）。 一旦被部署，螺旋锚自身向着线圈状转变，使阀环接合组织收紧。

公开(公告)号：US11963873B2

公开(公告)日：2024-04-23

申请号：US17087008

申请日：2020-11-02

Applicant: MEDTRONIC, INC.

Inventor： Jason Quill ,  Cynthia Clague ,  Michael Green ,  Alexander J. Hill ,  Ana Menk ,  Paul Rothstein ,  Georg Bortlein

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/064 ,  A61B17/068

CPC classification number: A61F2/2442 ,  A61B17/068 ,  A61B2017/00243 ,  A61B2017/00331 ,  A61B2017/00349 ,  A61B2017/00783 ,  A61B2017/0649 ,  A61F2/2412 ,  A61F2002/249 ,  A61F2230/0091

Abstract: Systems and methods for modifying a heart valve annulus in a minimally invasive surgical procedure. A helical anchor is provided, having a memory set to a coiled shape or state. The helical anchor is further configured to self-revert from a substantially straight state to the coiled state. The helical anchor is loaded within a needle that constrains the helical anchor to the substantially straight state. The needle is delivered to the valve annulus and inserted into tissue of the annulus. The helical anchor is then deployed from the needle (e.g., the needle is retracted from over the helical anchor). Once deployed, the helical anchor self-transitions toward the coiled shape, cinching engaged tissue of the valve annulus.

公开(公告)号：US09949831B2

公开(公告)日：2018-04-24

申请号：US14174268

申请日：2014-02-06

Applicant: Medtronic, Inc.

Inventor： James R. Keogh ,  Timothy R. Ryan ,  Carol E. Eberhardt ,  Mark T. Stewart ,  James R. Skarda ,  Timothy G. Laske ,  Alexander J. Hill ,  Jack D. Lemmon ,  David E. Francischelli

IPC: A61F2/24 ,  A61B5/00 ,  A61B5/107 ,  A61B8/00 ,  A61N7/02 ,  A61B18/14 ,  A61B17/00 ,  A61B18/00 ,  A61B34/20 ,  A61B90/00

CPC classification number: A61F2/2496 ,  A61B5/0044 ,  A61B5/1076 ,  A61B5/6853 ,  A61B8/445 ,  A61B18/1442 ,  A61B34/20 ,  A61B90/37 ,  A61B90/39 ,  A61B2017/00243 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2034/2051 ,  A61B2034/2063 ,  A61B2090/378 ,  A61B2090/397 ,  A61F2/2433 ,  A61F2210/009 ,  A61F2250/0096 ,  A61N7/02

Abstract: A method for determining whether a medical device is appropriate for implanting into a cardiovascular conduit of a patient is disclosed comprising imaging a first section of the conduit of the patient into which the medical device is to be implanted during a first expanded state occurring at a first portion of a heart rhythm; reimaging the first section of the conduit of the patient during a first contracted state occurring at a second portion of the heart rhythm; deriving, from the imaging and the reimaging, dimensional characteristics of the first section of the conduit; and determining whether the medical device is appropriate for implantation in the first section of conduit based on the derived dimensional characteristics. The first section of the conduit includes a sizing device providing a selected radial force on the patient.

公开(公告)号：US20170065412A1

公开(公告)日：2017-03-09

申请号：US15338124

申请日：2016-10-28

Applicant: Medtronic, Inc.

Inventor： Thierry Mesana ,  Timothy G. Laske ,  Allen Tower ,  Alexander J. Hill ,  Timothy R. Ryan

IPC: A61F2/24

Abstract: A compressible and expandable stent assembly for implantation in a body lumen such as a mitral valve, the stent assembly including at least one stent barrel that is shaped and sized so that it allows for normal operation of adjacent heart structures. One or more stent barrels can be included in the stent assembly, where one or more of the stent barrels can include a cylinder with tapered edge.

Abstract translation: 一种用于植入体腔（例如二尖瓣）的可压缩和可扩展的支架组件，所述支架组件包括至少一个成形和尺寸使其允许相邻心脏结构的正常操作的支架筒。 一个或多个支架套筒可以包括在支架组件中，其中一个或多个支架套筒可以包括具有锥形边缘的圆柱体。

公开(公告)号：US20170000608A1

公开(公告)日：2017-01-05

申请号：US15200929

申请日：2016-07-01

Applicant: Medtronic, Inc.

Inventor： Timothy R. Ryan ,  Alexander J. Hill ,  Jason L. Quill ,  Jerald L. Redmond ,  Stephen Kuehn ,  Eugene Grossi ,  Aubrey Galloway ,  Hugo Vanermen ,  Rudiger Lange

IPC: A61F2/24

CPC classification number: A61F2/2445 ,  A61B17/06066 ,  A61F2/2448 ,  A61F2230/0013

Abstract: Annuloplasty device for implantation adjacent an annulus of a tricuspid valve, the annulus comprising, anterior, posterior and septal aspects adjacent anterior, posterior and septal leaflets, respectively, of the tricuspid valve, the device comprising: a ring body comprising: an anterior portion, a posterior portion and a septal portion shaped to conform to, and for implantation adjacent, the anterior, posterior and septal aspects of the annulus, respectively; and first and second end portions that are more flexible than a remainder of the ring body to provide a gradual transition from the remainder of the ring body to tissue of the tricuspid valve annulus; wherein the ring body is curvilinear, with substantially no flat portions, and forming a shape. Related devices, kits and sizer devices.

Abstract translation: 用于植入邻近三尖瓣环的瓣膜成形术装置，所述环形空间包括分别邻近所述三尖瓣的前，后和间隔小叶的前，后和中隔方面，所述装置包括：环体，包括：前部， 后部和间隔部分，其分别成形为分别与环的前部，后部和中隔方面相邻并用于植入; 以及第一和第二端部，其比环体的其余部分更柔性，以提供从环体的其余部分到三尖瓣瓣环的组织的逐渐过渡; 其中所述环体是曲线形的，基本上没有平坦部分，并且形成形状。 相关设备，套件和分级设备。