公开(公告)号：US11685930B2

公开(公告)日：2023-06-27

申请号：US16988589

申请日：2020-08-07

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Larry A. Gilbertson ,  David K. Kovalic ,  Thomas J. LaRosa ,  Maolong Lu ,  Tichafa R. I. Munyikwa ,  James K. Roberts ,  Wei Wu ,  Bei Zhang

IPC: C12N15/82 ,  A01N63/50 ,  A01N63/60

CPC classification number: C12N15/8286 ,  A01N63/50 ,  A01N63/60 ,  C12N15/8275 ,  C12N15/8279 ,  C12N15/8285 ,  Y02A40/146 ,  A01N63/50 ,  A01N63/23

Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.

公开(公告)号：US20210310015A1

公开(公告)日：2021-10-07

申请号：US17229604

申请日：2021-04-13

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Barrett C. Foat ,  Mohammed Oufattole ,  Randall W. Shultz ,  Xiaoping Wei ,  Wei Wu ,  Shiaw-Pyng Yang

IPC: C12N15/82

Abstract: The invention provides DNA molecules and constructs, including their nucleotide sequences, useful for modulating gene expression in plants and plant cells. Transgenic plants, plant cells, plant parts, seeds, and commodity products comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided, as are methods of their use.

公开(公告)号：US20210230621A1

公开(公告)日：2021-07-29

申请号：US17165055

申请日：2021-02-02

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Charles R. Dietrich ,  Wei Wu ,  Zhaolong Li ,  Bo-Xing Qiu ,  Liang Guo ,  Jaishree M. Chittoor

IPC: C12N15/82 ,  C12N15/113

Abstract: The invention provides DNA molecules and constructs, and their nucleotide sequences, useful for modulating gene expression in plants, and for specifying intracellular or extracellular localization of a gene product of interest. Transgenic plants, plant cells, plant parts, and seeds, comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided.

公开(公告)号：US20190292542A1

公开(公告)日：2019-09-26

申请号：US16374211

申请日：2019-04-03

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Charles R. Dietrich ,  Wei Wu ,  Zhaolong Li ,  Bo-Xing Qiu ,  Liang Guo ,  Jaishree M. Chittoor

IPC: C12N15/113 ,  C12N15/82

Abstract: The invention provides DNA molecules and constructs, and their nucleotide sequences, useful for modulating gene expression in plants, and for specifying intracellular or extracellular localization of a gene product of interest. Transgenic plants, plant cells, plant parts, and seeds, comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided.

公开(公告)号：US20180155734A1

公开(公告)日：2018-06-07

申请号：US15881270

申请日：2018-01-26

Applicant: Monsanto Technology LLC

Inventor： Liang Guo ,  David Kovalic ,  Bo-Xing Qiu ,  Jack Tabaska ,  Wei Wu

IPC: C12N15/82 ,  A01H5/10 ,  C07K14/415

CPC classification number: C12N15/8218 ,  A01H5/10 ,  C07K14/415 ,  C12N15/8273 ,  C12N15/8274 ,  C12N15/8275 ,  C12N15/8278

Abstract: This disclosure provides purified nucleic acids and polypeptides. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of the proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants, methods of making such plants and methods of making agricultural commodity including seeds and hybrid seeds from such plants.

公开(公告)号：US20180073037A1

公开(公告)日：2018-03-15

申请号：US15709291

申请日：2017-09-19

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： James A. Baum ,  Larry A. Gilbertson ,  David K. Kovalic ,  Thomas J. LaRosa ,  Maolong Lu ,  Tichafa R.I. Munyikwa ,  James K. Roberts ,  Wei Wu ,  Bei Zhang

IPC: C12N15/82 ,  A01N63/02

CPC classification number: C12N15/8286 ,  A01N63/02 ,  C12N15/8275 ,  C12N15/8279 ,  C12N15/8285 ,  Y02A40/162 ,  Y02A40/164

Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.

公开(公告)号：US20180002690A1

公开(公告)日：2018-01-04

申请号：US15476701

申请日：2017-03-31

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Charles R. Dietrich ,  Wei Wu ,  Zhaolong Li ,  Bo-Xing Qiu ,  Liang Guo ,  Jaishree M. Chittoor

IPC: C12N15/113 ,  C12N15/82

CPC classification number: C12N15/113 ,  C12N15/8222

Abstract: The invention provides DNA molecules and constructs, and their nucleotide sequences, useful for modulating gene expression in plants, and for specifying intracellular or extracellular localization of a gene product of interest. Transgenic plants, plant cells, plant parts, and seeds, comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided.

公开(公告)号：US20170183684A1

公开(公告)日：2017-06-29

申请号：US15373377

申请日：2016-12-08

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Renata Bolognesi ,  Lex Evan Flagel ,  Gerrit Cornelis Segers ,  Larry A. Gilbertson ,  David K. Kovalic ,  Thomas J. LaRosa ,  Maolong Lu ,  Tichafa R. I. Munyikwa ,  James K. Roberts ,  Wei Wu ,  Bei Zhang

IPC: C12N15/82 ,  C12N15/113

CPC classification number: C12N15/8286 ,  A01N57/16 ,  C12N15/113 ,  C12N2310/14 ,  Y02A40/162

Abstract: The present invention provides methods for controlling invertebrate pest infestations, for instance in plants, and related compositions and polynucleotides useful in such methods. More specifically, the present invention provides polynucleotides and methods of use thereof for modifying the expression of genes in an invertebrate pest, for instance through RNA interference.

公开(公告)号：US20170029834A1

公开(公告)日：2017-02-02

申请号：US15222783

申请日：2016-07-28

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Shirley Xiaoli Guo ,  Wei Wu

IPC: C12N15/82 ,  C12N7/00

CPC classification number: C12N15/8216 ,  C12N15/8227 ,  C12N2730/00043

Abstract: The present invention provides regulatory polynucleotide molecules isolated from plant proline rich protein genes and linked to a viral enhancer molecule. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the regulatory polynucleotide sequences, and methods for preparing and using the same.

Abstract translation: 本发明提供从植物富含脯氨酸的蛋白质基因分离并连接到病毒增强子分子的调节性多核苷酸分子。 本发明进一步公开了组合物，多核苷酸构建体，转化的宿主细胞，含有调控多核苷酸序列的转基因植物和种子，以及制备和使用其的方法。

公开(公告)号：US09388409B2

公开(公告)日：2016-07-12

申请号：US14011647

申请日：2013-08-27

Applicant: Monsanto Technology LLC

Inventor： Andrey A. Boukharov ,  Zijin Du ,  Liang Guo ,  Michelle C. Hresko ,  David K. Kovalic ,  Zhaolong Li ,  Maolong Lu ,  James P. McCarter ,  Nancy M. Miller ,  Mark Vaudin ,  Deryck J. Williams ,  Wei Wu

IPC: C12N15/82 ,  C12N15/87 ,  A01H1/00 ,  C12N15/113 ,  C07K14/435 ,  A61K31/713

CPC classification number: C12N15/8285 ,  A01N57/16 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/713 ,  C07K14/435 ,  C07K14/4354 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/8261 ,  C12N15/8273 ,  C12N2310/11 ,  C12Q1/6888 ,  Y02A40/164

Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.