摘要:
The present invention relates to the IL-12p40 subunit mutant gene which can produce IL-12 (interleukin 12) of human and mouse origin with high activity, the expression vector including above mutant gene and the use of them to DNA vaccine adjuvant. Particularly, it relates to IL-12p40 mutant gene which inhibits the secretion of IL-12p40 but normally secretes active IL-12p70 by making mutation at Asn-222 (human) or Asn-220 (mouse) amino acid of IL-12p40, which acts as a competitive inhibitor of active form of IL-12, IL-12p70. Therefore, the IL-12p40 mutant gene of the present invention can be useful for DNA vaccination and gene therapy against various diseases, for example, AIDS, hepatitis C or hepatitis B, cancer, influenza, tuberculosis and malaria, which essentially require cellular immune responses for their therapy.
摘要:
Disclosed is a front substrate of a plasma display panel and fabricating method thereof, by which color temperature, color purity, and contrast of PDP are enhanced. The present invention includes an upper dielectric layer containing a colorant therein. And, the present invention includes the step of forming an upper dielectric layer having a colorant added thereto.
摘要:
A subminiature microphone and speaker having a plate spring structure and a speech recognition/synthesizing device using the microphone and speaker include frames, vibration plates, plate spring structures, elastic portions connected to the frames and the vibration plates, and sensor units which are disposed at the elastic portions and sense vibration of the vibration plates transmitted to the elastic portions.
摘要:
Provided is near-field optical probe including: a cantilever arm support portion that is formed of a lower silicon layer of a silicon-on-insulator (SOI) substrate, the cantilever arm support portion having a through hole formed therein at a side of the lower silicon layer; and a cantilever arm forming of a junction oxidation layer pattern and an upper silicon layer pattern on the SOI substrate that are supported on an upper surface of the lower silicon layer and each have a smaller hole than the through hole, a silicon oxidation layer pattern having a tip including an aperture at a vertical end, corresponding with the hole on the upper silicon layer pattern, and an optical transmission prevention layer that is formed on the silicon oxidation layer pattern and does not cover the aperture.
摘要:
Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetic structures have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetic structures of this invention are also disclosed as well as methods for screening the same to identify biologically active members. The invention also relates to the use of such compounds for inhibiting or treating disorders modulated by Wnt-signaling pathway, such as cancer, especially colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss, or ulcerative colitis.
摘要:
A prism sheet capable of achieving an enhancement in light efficiency and viewing angle characteristics and a backlight unit using the prism sheet are disclosed. The prism sheet includes: a condensing film which transmits light incident to the condensing film; a plurality of prism crests on the condensing film having apexes; and a plurality of reflection patterns formed on the condensing film such that each of the reflection patterns faces a boundary of adjacent prism crests associated with the reflection pattern to reflect light incident onto the reflection patterns.
摘要:
There is provided a plasma display apparatus and a driving method thereof. The plasma display apparatus includes a plasma display panel; and a scan driver commonly using a voltage source supplying a sustain pulse voltage, a setup bias voltage, a setdown pulse voltage, and a scan pulse voltage among a plurality of driving voltages supplied to a scan electrode of the plasma display panel.
摘要:
A method for controlling recording at a mobile terminal includes receiving a video signal having stream data, determining signal quality of the stream data, and obtaining loss information associated with a lost portion of the stream data responsive to the signal quality. In addition, a mobile terminal includes a receiver for receiving a video signal having stream data. The controller may be configured to determine signal quality of the stream data and obtain loss information associated with a lost portion of the stream data responsive to the signal quality. Alternatively, the mobile terminal includes a controller configured to obtain previously stored loss information, such that the loss information is associated with a lost portion of stream data of a video signal, and a receiver for receiving lost stream data corresponding to the loss information from a video data server responsive to an information request.
摘要:
A method of forming a bit line of a semiconductor device wherein an etch-stop nitride film, a trench oxide film and a hard mask nitride film are formed on a semiconductor substrate. The hard mask nitride film and the trench oxide film are etched to a limited etch thickness of a photo mask. The remaining trench oxide film is etched using the hard mask nitride film as a mask, thus forming a trench. The etch-stop nitride film and the hard mask nitride film are etched on condition that an oxide film has a high selectivity with respect to a nitride film. Accordingly, the loss of a top surface of the trench oxide film can be minimized and a bit line can be formed to have a uniform height. In accordance with the invention, bit line resistance and capacitance variation can be reduced and the reliability of a device can be improved.
摘要:
The present invention provides a light emitting diode (LED) package and the fabrication method thereof. The LED package includes a lower metal layer, and a first silicon layer, a first insulation layer, a second silicon layer, a second insulation layer, and a package electrode pattern formed in their order on the lower metal layer. The LED package also includes a spacer having a cavity, formed on the electrode pattern. The LED package further includes an LED mounted in the cavity by flip-chip bonding to the electrode patterns, and an optical element attached to the upper surface of the spacer.