公开(公告)号：US10065950B2

公开(公告)日：2018-09-04

申请号：US13034866

申请日：2011-02-25

申请人： Susumu Miyazaki ,  Yuki Bessho ,  Kaoru Adachi ,  Seiji Kawashita ,  Hirotaka Isoshima ,  Kengo Oshita ,  Shunichi Fukuda

发明人： Susumu Miyazaki ,  Yuki Bessho ,  Kaoru Adachi ,  Seiji Kawashita ,  Hirotaka Isoshima ,  Kengo Oshita ,  Shunichi Fukuda

IPC分类号： A61K31/427 ,  C07D277/20 ,  C07D471/04 ,  A61K31/4985 ,  A61K31/5377

摘要： [Problem] Provided is a novel 1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine derivative or a pharmaceutically acceptable salt thereof, or a solvate thereof, which is useful as an anti-HIV agent.[Solving Means] The present invention provides a compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof, or a solvate thereof.

公开(公告)号：US08038929B2

公开(公告)日：2011-10-18

申请号：US11946341

申请日：2007-11-28

申请人： Yuki Bessho ,  Hiroyuki Shindo

发明人： Yuki Bessho ,  Hiroyuki Shindo

IPC分类号： C04B35/01

CPC分类号： B22F3/225 ,  B22F1/0059 ,  B22F2998/00 ,  C04B35/111 ,  C04B35/624 ,  C04B35/6261 ,  C04B35/62625 ,  C04B35/6263 ,  C04B35/62635 ,  C04B35/62655 ,  C04B35/63 ,  C04B35/632 ,  C04B35/63424 ,  C04B2235/3217 ,  C04B2235/5409 ,  C04B2235/5445 ,  C04B2235/6021 ,  C04B2235/6022 ,  C04B2235/77 ,  B22F3/10 ,  B22F3/22

摘要： A method of manufacturing a sintered body is provided. A molding powder, a gel-forming material powder and a solvent are mixed at a temperature not higher than a dissolving point of the gel-forming material. A treatment of pulverizing agglomerates containing the molding powder, gel-forming material powder and solvent absorbed in the gel-forming material powder is carried out. The mixture is then heated to a temperature not lower than the dissolving point thereby forming a sol. The sol is then cooled to a temperature not higher than the gel point, thereby forming a molding material. The molding material is used for producing a sintering body.

摘要翻译： 提供一种制造烧结体的方法。 将成型粉末，凝胶形成材料粉末和溶剂在不高于凝胶形成材料的溶解点的温度下混合。 进行粉碎含有成型粉末，凝胶形成材料粉末和凝胶形成材料粉末中吸收的溶剂的附聚物的处理。 然后将混合物加热至不低于溶解点的温度，从而形成溶胶。 然后将溶胶冷却至不高于凝胶点的温度，从而形成模塑材料。 成型材料用于制造烧结体。

公开(公告)号：US07518131B2

公开(公告)日：2009-04-14

申请号：US11385483

申请日：2006-03-21

申请人： Tsutomu Nanataki ,  Iwao Ohwada ,  Yuki Bessho ,  Takayoshi Akao

发明人： Tsutomu Nanataki ,  Iwao Ohwada ,  Yuki Bessho ,  Takayoshi Akao

IPC分类号： A61N5/00

CPC分类号： G21K5/04 ,  H01J37/317 ,  H01L21/67005

摘要： An electron beam irradiating apparatus includes a chamber being kept under vacuum, and housing a planar electron emitting element and a positioning unit and an object to be irradiated is directly irradiated with an electron beam emitted from the element. The planar electron emitting element includes: an emitter portion composed of a dielectric material; and a first electrode and a second electrode applied with a driving voltage for emitting electrons, and the first electrode is formed on a first surface of the emitter portion and has a plurality of through-holes where the emitter portion is exposed, a surface of the first electrode facing to the emitter portion around the through-holes is separated from the emitter portion, and the electron beam is emitted from the first surface of the emitter portion through the through-holes.

摘要翻译： 电子束照射装置包括保持在真空下的室，并容纳平面电子发射元件和定位单元，并且被照射物体直接用从元件发射的电子束照射。 平面电子发射元件包括：由电介质材料构成的发射极部分; 以及施加有用于发射电子的驱动电压的第一电极和第二电极，并且所述第一电极形成在所述发射极部分的第一表面上，并且具有多个通过所述发射极部分露出的通孔， 面向通孔周围的发射极部分的第一电极与发射极部分分离，并且电子束通过通孔从发射器部分的第一表面发射。

公开(公告)号：US20050008545A1

公开(公告)日：2005-01-13

申请号：US10886258

申请日：2004-07-06

申请人： Yuki Bessho ,  Yukihisa Takeuchi

发明人： Yuki Bessho ,  Yukihisa Takeuchi

IPC分类号： B01J19/00 ,  B01L3/00 ,  B01L3/02 ,  F04B43/04

CPC分类号： B01L3/50273 ,  B01J19/0093 ,  B01J2219/00162 ,  B01J2219/00164 ,  B01J2219/00783 ,  B01J2219/00824 ,  B01J2219/00833 ,  B01J2219/00853 ,  B01J2219/00867 ,  B01J2219/00891 ,  B01J2219/0095 ,  B01L3/0241 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2400/0439 ,  B01L2400/0442 ,  F04B43/046

摘要： A micro reactor comprising: a first substrate comprising a predetermined number each of micro channels, reactors connected to micro channels at respective connection points, injection ports for feeding/receiving a sample solution, and discharge ports for recovering a sample solution after reaction from respective reactors; and a second substrate in which at least one micro pump is disposed so as to be faced to the injection ports and the discharge ports, the at least one micro pump being provided with a substrate including a cavity made of a ceramic in the inner surface thereof; a piezoelectric/electrostrictive operation section formed on the outer surface of the substrate, and at least two connection ports for feeding/receiving a sample solution in the cavity; and the micro reactor being formed integrally by laminating the first substrate and the second substrate.

摘要翻译： 一种微反应器，包括：包含预定数量的每个微通道的第一基板，在相应连接点处连接到微通道的反应器，用于进料/接收样品溶液的注入口和用于从各个反应器反应后回收样品溶液的排出口 ; 以及第二基板，其中至少一个微泵设置成面对所述喷射口和所述排出口，所述至少一个微型泵设置有在其内表面中包括由陶瓷制成的空腔的基板 ; 形成在所述基板的外表面上的压电/电致伸缩操作部，以及用于在所述空腔内供给/接收样品溶液的至少两个连接端口; 并且所述微反应器通过层叠所述第一基板和所述第二基板而一体地形成。

公开(公告)号：US20080117713A1

公开(公告)日：2008-05-22

申请号：US11946341

申请日：2007-11-28

申请人： Yuki Bessho ,  Hiroyuki Shindo

发明人： Yuki Bessho ,  Hiroyuki Shindo

IPC分类号： B01F15/06

CPC分类号： B22F3/225 ,  B22F1/0059 ,  B22F2998/00 ,  C04B35/111 ,  C04B35/624 ,  C04B35/6261 ,  C04B35/62625 ,  C04B35/6263 ,  C04B35/62635 ,  C04B35/62655 ,  C04B35/63 ,  C04B35/632 ,  C04B35/63424 ,  C04B2235/3217 ,  C04B2235/5409 ,  C04B2235/5445 ,  C04B2235/6021 ,  C04B2235/6022 ,  C04B2235/77 ,  B22F3/10 ,  B22F3/22

摘要： A method of manufacturing a sintered body is provided. A molding powder, a gel-forming material powder and a solvent are mixed at a temperature not higher than a dissolving point of the gel-forming material. A treatment of pulverizing agglomerates containing the molding powder, gel-forming material powder and solvent absorbed in the gel-forming material powder is carried out. The mixture is then heated to a temperature not lower than the dissolving point thereby forming a sol. The sol is then cooled to a temperature not higher than the gel point, thereby forming a molding material. The molding material is used for producing a sintering body.

摘要翻译： 提供一种制造烧结体的方法。 将成型粉末，凝胶形成材料粉末和溶剂在不高于凝胶形成材料的溶解点的温度下混合。 进行粉碎含有成型粉末，凝胶形成材料粉末和凝胶形成材料粉末中吸收的溶剂的附聚物的处理。 然后将混合物加热至不低于溶解点的温度，从而形成溶胶。 然后将溶胶冷却至不高于凝胶点的温度，从而形成模塑材料。 成型材料用于制造烧结体。

公开(公告)号：US20070040130A1

公开(公告)日：2007-02-22

申请号：US11385483

申请日：2006-03-21

申请人： Tsutomu Nanataki ,  Iwao Ohwada ,  Yuki Bessho ,  Takayoshi Akao

发明人： Tsutomu Nanataki ,  Iwao Ohwada ,  Yuki Bessho ,  Takayoshi Akao

IPC分类号： A61N5/00

CPC分类号： G21K5/04 ,  H01J37/317 ,  H01L21/67005

摘要： An electron beam irradiating apparatus includes a chamber being kept under vacuum, and housing a planar electron emitting element and a positioning unit and an object to be irradiated is directly irradiated with an electron beam emitted from the element. The planar electron emitting element includes: an emitter portion composed of a dielectric material; and a first electrode and a second electrode applied with a driving voltage for emitting electrons, and the first electrode is formed on a first surface of the emitter portion and has a plurality of through-holes where the emitter portion is exposed, a surface of the first electrode facing to the emitter portion around the through-holes is separated from the emitter portion, and the electron beam is emitted from the first surface of the emitter portion through the through-holes.

摘要翻译： 电子束照射装置包括保持在真空下的室，并容纳平面电子发射元件和定位单元，并且被照射物体直接用从元件发射的电子束照射。 平面电子发射元件包括：由电介质材料构成的发射极部分; 以及施加有用于发射电子的驱动电压的第一电极和第二电极，并且所述第一电极形成在所述发射极部分的第一表面上，并且具有多个通过所述发射极部分露出的通孔， 面向通孔周围的发射极部分的第一电极与发射极部分分离，并且电子束通过通孔从发射器部分的第一表面发射。

公开(公告)号：US06174583B1

公开(公告)日：2001-01-16

申请号：US09391381

申请日：1999-09-08

申请人： Naohito Yamada ,  Yukimasa Mori ,  Yuki Bessho ,  Hiromichi Kobayashi

发明人： Naohito Yamada ,  Yukimasa Mori ,  Yuki Bessho ,  Hiromichi Kobayashi

IPC分类号： B32B1500

CPC分类号： C04B35/581 ,  C04B37/021 ,  C04B2237/366 ,  C04B2237/40 ,  C04B2237/402 ,  C04B2237/403 ,  C04B2237/404 ,  C04B2237/408 ,  C04B2237/62 ,  C04B2237/704 ,  C04B2237/706 ,  Y10T279/23 ,  Y10T428/22 ,  Y10T428/31678

摘要： An aluminum nitride sintered body has characteristics such that an amount of total metal elements other than aluminum is smaller than 100 ppm, and a volume resistivity at room temperature is greater than 1.0×109 &OHgr;·cm and is smaller than 1.0×1013 &OHgr;·cm. A metal including member has such a construction that a metal member is embedded in the aluminum nitride sintered body mentioned above. An electrostatic chuck is made by the metal including member mentioned above. In the metal including member mentioned above in which the metal member is embedded in the aluminum nitride sintered body mentioned above, a volume resistivity thereof can be controlled without adding a low resistance material in aluminum nitride.

摘要翻译： 氮化铝烧结体具有以下特性：除了铝以外的总金属元素的量小于100ppm，室温下的体积电阻率大于1.0×10 9欧米汞厘米，小于1.0×10 13欧姆·厘米。 包含金属的构件具有金属构件嵌入在上述氮化铝烧结体中的结构。 由上述金属构成的静电卡盘构成。 在上述金属构件中，金属构件嵌入上述的氮化铝烧结体中，其体积电阻率可以在氮化铝不添加低电阻材料的情况下进行控制。

公开(公告)号：US6001760A

公开(公告)日：1999-12-14

申请号：US824560

申请日：1997-03-25

申请人： Yuji Katsuda ,  Yukimasa Mori ,  Michio Takahashi ,  Yuki Bessho

发明人： Yuji Katsuda ,  Yukimasa Mori ,  Michio Takahashi ,  Yuki Bessho

IPC分类号： C04B35/581 ,  H01L21/683

CPC分类号： C04B35/581 ,  H01L21/6833 ,  Y10T279/23

摘要： In AlN crystal grains constituting a sintered body, is contained: 150 ppm-0.5 wt. %, preferably at most 0.1 wt.%, of at least one rare earth element (as oxide thereof); at most 900 ppm, preferably at most 500 ppm of at least one metal impurity except rare earth elements; and preferably at least 0.5 wt. % of oxygen measured by an electron probe X-ray microanalyzer. The grains have an average grain diameter of preferably at least 3.0 .mu.m and show a main peak in the wavelength range of 350-370 nm of spectrum obtained by a cathode luminescence method. The sintered body composed of AlN crystal grains has a volume resistivity at room temperature of at most 1.0.times.10.sup.12 .OMEGA..multidot.cm.

摘要翻译： 在构成烧结体的AlN晶粒中含有150ppm-0.5wt。 ％，优选至多0.1重量％的至少一种稀土元素（作为其氧化物）; 至少一个金属杂质除了稀土元素之外，最多900ppm，优选至多500ppm; 优选至少0.5wt。 通过电子探针X射线微量分析仪测量的氧的百分比。 晶粒的平均粒径优选为3.0μm以上，在通过阴极发光法得到的光谱的350〜370nm的波长范围内呈现主峰。 由AlN晶粒构成的烧结体的体积电阻率在室温下为1.0×10 12Ω以下，OMEGA×cm。

公开(公告)号：US5908799A

公开(公告)日：1999-06-01

申请号：US922023

申请日：1997-09-02

申请人： Hiromichi Kobayashi ,  Yuki Bessho ,  Yukimasa Mori

发明人： Hiromichi Kobayashi ,  Yuki Bessho ,  Yukimasa Mori

IPC分类号： C04B35/581 ,  H01L23/15

CPC分类号： H01L23/15 ,  C04B35/581 ,  H01L2924/0002 ,  H01L2924/09701 ,  Y10S156/914

摘要： An aluminum nitride sintered body is characterized by having a g-value of an unpaired electron in a spectrum of an electron spin resonance being not less than 2.0010. The aluminum nitride sintered body is produced by sintering a raw material composed of powdery aluminum nitride at a temperature of not less than 1730.degree. C. to not more than 1920.degree. under a pressure of not less than 80 kg/cm.sup.2.

摘要翻译： 氮化铝烧结体的特征在于在电子自旋共振谱中具有不成对电子的g值不小于2.0010。 氮化铝烧结体通过在不低于80kg / cm 2的压力下在不低于1730℃至不超过1920℃的温度下烧结由氮化铝粉末组成的原料来制备。