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公开(公告)号:US12125691B2
公开(公告)日:2024-10-22
申请号:US18208116
申请日:2023-06-09
Applicant: Purdue Research Foundation
Inventor: Robert Graham Cooks , Alan Keith Jarmusch , Valentina Pirro
CPC classification number: H01J49/0459 , A61B5/14503 , A61B5/7282 , A61B10/02 , A61F13/38 , G01N30/72 , H01J49/0409 , H01J49/165 , G01N2001/028
Abstract: The invention generally relates to systems and methods for sample analysis using swabs. In certain aspects, the invention provides systems that include a probe having a conductive proximal portion coupled to a porous material at a distal portion of the probe that is configured to retain a portion of a sample that has contacted the porous material, and a mass spectrometer having an inlet. The system is configured such that the porous material at a distal portion of the probe is aligned over the inlet of the mass spectrometer.
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公开(公告)号:US20210358732A1
公开(公告)日:2021-11-18
申请号:US17179715
申请日:2021-02-19
Applicant: Purdue Research Foundation
Inventor: Robert Graham Cooks , Ahmed Mohamed Hamid , Alan Keith Jarmusch , Zheng Ouyang
Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
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公开(公告)号:US10204772B2
公开(公告)日:2019-02-12
申请号:US15902068
申请日:2018-02-22
Applicant: Purdue Research Foundation
Inventor: Robert Graham Cooks , Ahmed Mohamed Hamid , Alan Keith Jarmusch , Zheng Ouyang
Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
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公开(公告)号:US20150147776A1
公开(公告)日:2015-05-28
申请号:US14594233
申请日:2015-01-12
Applicant: PURDUE RESEARCH FOUNDATION
Inventor: Robert Graham Cooks , Ahmed Mohamed Hamid , Alan Keith Jarmusch , Zheng Ouyang
CPC classification number: H01J49/0036 , C12Q1/04 , G01N2560/00 , H01J49/04 , H01J49/0409 , H01J49/0422 , H01J49/10 , H01J49/16 , H01J49/26
Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
Abstract translation: 本发明一般涉及样品中微生物的质谱分析系统和方法。
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公开(公告)号:US08937288B1
公开(公告)日:2015-01-20
申请号:US14481483
申请日:2014-09-09
Applicant: Purdue Research Foundation
Inventor: Robert Graham Cooks , Ahmed Mohamed Hamid , Alan Keith Jarmusch , Zheng Ouyang
CPC classification number: H01J49/0036 , C12Q1/04 , G01N2560/00 , H01J49/04 , H01J49/0409 , H01J49/0422 , H01J49/10 , H01J49/16 , H01J49/26
Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
Abstract translation: 本发明一般涉及样品中微生物的质谱分析系统和方法。
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公开(公告)号:US20150017712A1
公开(公告)日:2015-01-15
申请号:US14481483
申请日:2014-09-09
Applicant: PURDUE RESEARCH FOUNDATION
Inventor: Robert Graham Cooks , Ahmed Mohamed Hamid , Alan Keith Jarmusch , Zheng Ouyang
CPC classification number: H01J49/0036 , C12Q1/04 , G01N2560/00 , H01J49/04 , H01J49/0409 , H01J49/0422 , H01J49/10 , H01J49/16 , H01J49/26
Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
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公开(公告)号:US10811241B2
公开(公告)日:2020-10-20
申请号:US16809171
申请日:2020-03-04
Applicant: Purdue Research Foundation
Inventor: Robert Graham Cooks , Ahmed Mohamed Hamid , Alan Keith Jarmusch , Zheng Ouyang
Abstract: The invention generally relates to methods for analyzing an analyte in a sample. In certain embodiments, the methods involve providing a capture module, the module configured to capture an analyte in a sample in an ambient environment and generate ions of the analyte, wherein the capture module comprises a cartridge and a porous substrate within the cartridge that is connected to a voltage source, and wherein the porous substrate further comprises an internal standard; capturing the analyte in the sample to the porous substrate of the capture module; generating ions of the analyte and the internal standard held by the porous substrate via the voltage source that is coupled to the porous substrate; and analyzing the generated ions of the analyte and the internal standard in a mass analyzer that is operably coupled to the capture module.
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公开(公告)号:US09941105B2
公开(公告)日:2018-04-10
申请号:US15483132
申请日:2017-04-10
Applicant: Purdue Research Foundation
Inventor: Robert Graham Cooks , Ahmed Mohamed Hamid , Alan Keith Jarmusch , Zheng Ouyang
CPC classification number: H01J49/0445 , C12N13/00 , C12Q1/04 , G01N2560/00 , H01J49/16
Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
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公开(公告)号:US20170309462A1
公开(公告)日:2017-10-26
申请号:US15483132
申请日:2017-04-10
Applicant: Purdue Research Foundation
Inventor: Robert Graham Cooks , Ahmed Mohamed Hamid , Alan Keith Jarmusch , Zheng Ouyang
CPC classification number: H01J49/0445 , C12N13/00 , C12Q1/04 , G01N2560/00 , H01J49/16
Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
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公开(公告)号:US20170248607A1
公开(公告)日:2017-08-31
申请号:US15407876
申请日:2017-01-17
Applicant: Purdue Research Foundation
Inventor: Robert Graham Cooks , Kevin Scott Kerian , Alan Keith Jarmusch , Ahmed Mohamed Hamid , Livia Schiavinato Eberlin
IPC: G01N33/68 , G01N33/574 , H01J49/00 , G01N27/62 , H01J49/16
CPC classification number: G01N33/6848 , G01N27/62 , G01N33/50 , G01N33/57407 , G01N2560/00 , G01N2800/7028 , H01J49/0004 , H01J49/0031 , H01J49/142 , H01J49/165
Abstract: The invention generally relates to methods for analyzing a metabolite level in a sample. In certain embodiments, methods of the invention may involve obtaining a sample, analyzing the sample using a mass spectrometry technique to determine a level of at least one metabolite in the sample, and correlating the metabolite level with an originating source of the sample, thereby analyzing the sample.
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