公开(公告)号：US09102717B2

公开(公告)日：2015-08-11

申请号：US13581785

申请日：2011-02-25

申请人： Yadong Huang ,  Qin Xu ,  Thu Nga Bien-Ly ,  Karl H. Weisgraber ,  Ligong Chen ,  Clare Peters-Libeu

发明人： Yadong Huang ,  Qin Xu ,  Thu Nga Bien-Ly ,  Karl H. Weisgraber ,  Ligong Chen ,  Clare Peters-Libeu

IPC分类号： C07K16/00 ,  C12P21/08 ,  A61K39/395 ,  A61K39/00 ,  C07K16/18

CPC分类号： C07K16/18 ,  C07K2317/34 ,  C07K2317/76

摘要： The present disclosure provides synthetic antibodies specific for an epitope present on an apolipoprotein E polypeptide. The antibodies are useful in various treatment, diagnostic, and monitoring applications, which are also provided.

摘要翻译： 本公开提供对存在于载脂蛋白E多肽上的表位特异性的合成抗体。 抗体可用于各种治疗，诊断和监测应用，这些也被提供。

公开(公告)号：US20130062185A1

公开(公告)日：2013-03-14

申请号：US13640696

申请日：2011-03-07

申请人： Qin Xu ,  Congjun Wang

发明人： Qin Xu ,  Congjun Wang

IPC分类号： C10B7/00 ,  C10B57/04 ,  C10B53/08

CPC分类号： C10B47/46 ,  C10B7/14 ,  C10B53/08 ,  Y02P20/129

摘要： The invention refers to a tunnel typed coking furnace with a movable sliding bed and the method using the same belonging to the coking field, comprising a furnace body (48), a front sealing door (7), a back sealing door (25), a branch flue (10), a bottom flue (12) and a main flue (6), comprising a first preparation chamber (3) for coaling, a preheating segment (50), a carbonization segment (51), a coke dry quenching segment (52), and a second preparation chamber (23) for coke outlet; each part has different formation from the others, and are interconnected in series with the others; the sliding bed (37) for coaling and tamping coal material (44) passes through the abovementioned five segment in series in order to coke. The invention may realize a production coal material with fixed formation through formation process with pressure, so as to obtain the coke product with the same and big size, in addition to high strength, high utilization rate of heat energy, high degree of mechanization, and it also may realize the clean exhaustion of flue, so as to be able to protect the environment and water resource, and realize clean production.

摘要翻译： 本发明涉及一种具有可移动滑动床的隧道式焦化炉及其使用方法，包括炉体（48），前密封门（7），后密封门（25）， 分支烟道（10），底部烟道（12）和主烟道（6），包括用于堆肥的第一制备室（3），预热段（50），碳化段（51），焦炭干燥淬火 段（52）和用于焦炭出口的第二制备室（23） 每个部分与其他部分不同，与其他部分相互串联; 用于烧结和捣碎煤材料（44）的滑动床（37）通过上述五个片段串联以便焦化。 本发明除了具有高强度，高能量利用率，高机械化能力以外，还可以通过形成压力实现具有固定形成的生产煤材料，以获得大小相同和大的焦炭产品 也可以实现烟道清洁耗尽，从而能够保护环境和水资源，实现清洁生产。

公开(公告)号：US20120129782A1

公开(公告)日：2012-05-24

申请号：US13130003

申请日：2009-11-20

申请人： Yadong Huang ,  Qin Xu ,  Mei Xiu Steele ,  Robert W. Mahley ,  Karl H. Weisgraber ,  Stephen Barry Freedman

发明人： Yadong Huang ,  Qin Xu ,  Mei Xiu Steele ,  Robert W. Mahley ,  Karl H. Weisgraber ,  Stephen Barry Freedman

IPC分类号： A61K38/02 ,  C12Q1/37 ,  A61P25/28 ,  A61K31/713 ,  A61P29/00

CPC分类号： C12N15/1137 ,  A61K31/7088 ,  A61K45/06 ,  C07K14/775 ,  C12N2310/14 ,  C12N2310/531 ,  C12Y304/21092 ,  G01N33/92 ,  G01N2333/96433 ,  G01N2500/02 ,  G01N2800/2821 ,  A61K2300/00

摘要： The present invention provides methods for treating apoE-related disorders. The methods generally involve administering an effective amount of an agent that inhibits activity of an enzyme that cleaves apoE.

摘要翻译： 本发明提供了治疗apoE相关疾病的方法。 所述方法通常涉及施用有效量的抑制切割apoE的酶活性的试剂。

公开(公告)号：USD1007729S1

公开(公告)日：2023-12-12

申请号：US29894239

申请日：2023-06-07

申请人： Qin Xu

设计人： Qin Xu

摘要： FIG. 1 is a perspective view of a combined clock and night light showing my new design;
FIG. 2 is another perspective view thereof;
FIG. 3 is a front elevational view thereof;
FIG. 4 is a rear elevational view thereof;
FIG. 5 is a left side elevational view thereof;
FIG. 6 is a right side elevational view thereof;
FIG. 7 is a top plan view thereof; and,
FIG. 8 is a bottom plan view thereof.
The dash-dash broken lines in the drawings depict portions of the combined clock and night light that form no part of the claimed design.

公开(公告)号：US07771967B2

公开(公告)日：2010-08-10

申请号：US11960229

申请日：2007-12-19

申请人： Yadong Huang ,  Qin Xu

发明人： Yadong Huang ,  Qin Xu

IPC分类号： C12P21/06 ,  C12P21/04 ,  C12P1/00 ,  C12P19/34 ,  C12N15/00 ,  C12N1/20 ,  C07H21/02 ,  A01N63/00

CPC分类号： C07K14/775 ,  C12Q1/6883 ,  C12Q2600/136 ,  C12Q2600/142 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/5058 ,  G01N2333/775

摘要： The present invention provides nucleic acids comprising a nucleotide sequence encoding an apolipoprotein E (apoE) splice variant, e.g., an unprocessed apoE, that retains intron 3; and vectors and host cells comprising same. The present invention further provides screening methods to identify agents that inhibit cleavage of intron-3 from the apoE splice variant. The present invention further provides methods of treating apoE-related neurological disorders, involving administering an agent that inhibits removal of intron-3 from a precursor apoE mRNA.

摘要翻译： 本发明提供核酸，其包含编码保留内含子3的载脂蛋白E（apoE）剪接变体（例如未加工的apoE）的核苷酸序列; 以及包含其的载体和宿主细胞。 本发明还提供了鉴定抑制内含子-3从apoE剪接变体切割的试剂的筛选方法。 本发明还提供了治疗apoE相关神经系统疾病的方法，包括施用抑制内含子-3从前体apoE mRNA去除的药剂。

公开(公告)号：US20100038996A1

公开(公告)日：2010-02-18

申请号：US12228943

申请日：2008-08-18

申请人： Qin Xu ,  David A. Henderson

发明人： Qin Xu ,  David A. Henderson

IPC分类号： H02N2/04 ,  H01L41/22 ,  G02B7/09

CPC分类号： H02N2/026 ,  H02N2/0015 ,  H02N2/062 ,  H02N2/065 ,  H02N2/103 ,  H02N2/142 ,  H02N2/147 ,  Y10T29/42

摘要： A driving system in accordance with embodiments of the present invention includes a structure and a vibration system. The structure has at least one point to frictional couple to and drive a movable element in one of at least two directions. The structure also has at least two bending modes which each have a different resonant frequency. The vibration system applies two or more vibration signals which are at a vibration frequency to each of the bending modes of the structure. The vibration frequency is substantially the same as one of the resonant frequencies. At the vibration frequency one of the bending modes of the structure is vibrating substantially at resonance and the other of the bending modes of the structure is vibrating at partial resonance. The vibration system adjusts a phase shift between the two or more applied vibration signals to control which one of the at least two directions the moveable element is moved.

摘要翻译： 根据本发明的实施例的驱动系统包括结构和振动系统。 该结构具有至少一个点以摩擦联接到至少两个方向之一并驱动可移动元件。 该结构还具有至少两个各自具有不同谐振频率的弯曲模式。 振动系统将两个或更多个振动频率施加到结构的每个弯曲模式。 振动频率基本上与谐振频率之一相同。 在振动频率下，结构的一个弯曲模式基本上在共振时振动，并且结构的另一个弯曲模式在部分谐振下振动。 所述振动系统调整所述两个或更多施加的振动信号之间的相移，以控制所述至少两个方向中的所述可移动元件中的哪一个被移动。

公开(公告)号：US07045932B2

公开(公告)日：2006-05-16

申请号：US10793365

申请日：2004-03-04

申请人： Qin Xu ,  John C Fasick

发明人： Qin Xu ,  John C Fasick

IPC分类号： H02N2/02 ,  H02N2/04

CPC分类号： H02N2/101 ,  H02N2/023

摘要： Electromechanical translation apparatus provides power-off clamping because each clamp assembly comprises pressure means and clamp actuator means acting in opposition. The pressure means is arranged, when the actuator is de-energized, to apply clamping force to releasably clamp the associated movable member to the clamp assembly. The clamp actuator means is arranged, when energized, to act against the pressure means to release the movable member.

摘要翻译： 机电转换装置提供断电夹紧，因为每个夹具组件包括压力装置和夹紧致动器装置相对起作用。 当致动器断电时，压力装置被布置成施加夹紧力以将相关联的可移动构件可释放地夹紧到夹具组件。 夹紧致动器装置在通电时布置成抵抗压力装置以释放可动构件。

公开(公告)号：US09057596B2

公开(公告)日：2015-06-16

申请号：US13609863

申请日：2012-09-11

申请人： Qin Xu ,  Jonathan Geisheimer ,  Gérald Egger ,  Maddalena Violetti ,  Anja Skrivervik Favre

发明人： Qin Xu ,  Jonathan Geisheimer ,  Gérald Egger ,  Maddalena Violetti ,  Anja Skrivervik Favre

IPC分类号： G01N29/14 ,  G01B7/14 ,  G01B15/00

CPC分类号： G01B7/14 ,  G01B15/00 ,  G01N29/14

摘要： A device and a method for monitoring the operational state of rotor blades of a turbine from a position facing the blade tip of a passing rotor blade: A wavesource generates an electromagnetic wave and a wave guide directs the wave towards the blade tip. The waveguide is included in a resonator defining at least one discrete resonance frequency of the wave on the waveguide. An aperture at its front end emits an energy fraction of the wave toward the blade tip. The frequency of the wave is adjusted to the resonance frequency of the resonator at the momentary operation conditions, and a measuring unit compares at least one measurement parameter of the wave directed towards the blade tip with the corresponding measurement parameter of the wave reflected from the blade tip.

摘要翻译： 一种用于从面向通过的转子叶片的叶片尖端的位置监测涡轮机的转子叶片的操作状态的装置和方法：波源产生电磁波，波导将波导引向叶片尖端。 波导包括在限定波导上的波的至少一个离散谐振频率的谐振器中。 其前端的孔朝向叶片尖端发射波的能量分数。 在瞬时操作条件下，将波的频率调节到谐振器的谐振频率，并且测量单元将指向叶片尖端的波的至少一个测量参数与从叶片反射的波的相应测量参数进行比较 小费。

公开(公告)号：US20110241851A1

公开(公告)日：2011-10-06

申请号：US12751662

申请日：2010-03-31

申请人： David A. Henderson ,  Qin Xu

发明人： David A. Henderson ,  Qin Xu

IPC分类号： H04B3/36

CPC分类号： B06B1/16 ,  H02N2/0015 ,  H02N2/105

摘要： A haptic actuator system and a method of making the same include an ultrasonically vibrating motor body. A shaft is coupled to the vibrating motor body, the shaft arranged to rotate in at least one direction in response to the vibrating motor body. At least one unbalanced mass is coupled to and is moveable with the shaft to generate human-detectable vibrations in response to a motion of the shaft.

摘要翻译： 触觉致动器系统及其制造方法包括超声振动电动机体。 轴连接到振动电动机主体，轴被布置成响应于振动电动机主体在至少一个方向上旋转。 至少一个不平衡质量块与轴联接并且可移动，以响应于轴的运动而产生人可检测的振动。

公开(公告)号：US20100289381A1

公开(公告)日：2010-11-18

申请号：US12466929

申请日：2009-05-15

申请人： Qin Xu ,  Tom Guidarelli ,  Robert Culhane ,  Conrad Hoffman

发明人： Qin Xu ,  Tom Guidarelli ,  Robert Culhane ,  Conrad Hoffman

IPC分类号： H02N2/14

CPC分类号： H02N2/0095 ,  H02N2/0015 ,  H02N2/008 ,  H02N2/02 ,  H02N2/067

摘要： An actuator system includes an actuator device comprising at least one piezoelectric member, a driving system, and an actuator controller. The driving system drives the at least one piezoelectric member at a driving frequency. The actuator controller monitors at least one parameter of the actuator device and the direct driving system to determine an operational mechanical resonant frequency of the actuator device based on the at least one parameter. The actuator controller adjusts the driving frequency based at least in part on the determined operational mechanical resonant frequency.

摘要翻译： 致动器系统包括致动器装置，该致动器装置包括至少一个压电元件，驱动系统和致动器控制器。 驱动系统以驱动频率驱动至少一个压电构件。 致动器控制器监视致动器装置和直接驱动系统的至少一个参数，以基于至少一个参数来确定致动器装置的操作机械共振频率。 致动器控制器至少部分地基于所确定的操作机械共振频率来调节驱动频率。