摘要:
The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.
摘要:
The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.
摘要:
The present invention is directed to polymer compositions with flame retardant properties that are made from a polymer blended using a defined process with a smectite clay that has been reacted with a specified mixture of organic materials. The inventive compositions have the property that when the organically modified clay is added to the polymer, a composite results which has flame-retardant properties and is based on the finding that degree of dispersion of a smectite organoclay in a polymer matrix will give the compositions flame-retardant properties. Further, it has been found that it is very important to proper functioning of the flame retardant polymer compositions that they have the organoclay dispersed in the polymer such that it is not completely exfoliated.
摘要:
Benzamide derivatives of formula I are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, and n are as defined herein.
摘要:
The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.
摘要:
Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds. A representative thienyl compound has the structure
摘要:
This invention is of a hybrid organoclay that consists of an organic chemical/phyllosilicate clay intercalate that has been ion-exchanged with quaternary ammonium compounds. Since this hybrid organoclay is hydrophobic, it can be washed in water to remove reaction salts and excess water soluble or water dispersible polymers to give a clean product via inexpensive means such as filtration. This allows a better dispersing composition to be prepared without the difficulties of isolation presented by prior art which uses energy intensive means to remove the bulk of the water from the final product and cannot be easily washed. In one aspect, the present invention provides a solid clay/chemical composition that comprises: (a) one or more smectite clays, (b) a quaternary ammonium compound which reacts via an ion exchange mechanism with the smectite clay, and (c) one or more non-anionic organic materials that intercalate with the clay. The invention is useful both as an ingredient to form nanocomposites and as a rheological additive.