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公开(公告)号：US12274775B2
公开(公告)日：2025-04-15
申请号：US17428309
申请日：2019-02-04
Applicant: SYMRISE AG
Inventor： Peter Mayser , Manuel Pesaro , Gerhard Schmaus , Jessica Grieger , Nikolas Bugdahn
Abstract: The present invention primarily relates to a fatty acid ester or mixture of two or more fatty acid esters or mixture comprising one or more fatty acid esters, wherein the fatty acid ester or one, two, three or more, preferably all, of the fatty acid ester(s) is/are selected from the group consisting of 3-hydroxypropyl caprylate, glyceryl monocaprylate, 3-hydroxypropyl undecylenate and glyceryl monoundecylenate, for use in the treatment of an excess of Malassezia on the skin surface of mammals, preferably of humans. The present invention further relates to particular mixtures or products, and to the cosmetic, non-therapeutic use of fatty acid esters or of mixtures or products comprising fatty acid esters as defined herein to reduce the amount of Malassezia on the skin surface of mammals, preferably of humans.
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公开(公告)号：US20230338249A1
公开(公告)日：2023-10-26
申请号：US18009314
申请日：2021-12-09
Applicant: Symrise AG
Inventor： Nikolas Bugdahn , Sabine Lange , Christin Koch , Frank Struever , Dietmar Droege
CPC classification number: A61K8/345 , A61K47/10 , A61K2800/10 , A61K2800/49 , A61K2800/522 , A61K2800/524 , A61K2800/5922
Abstract: The present invention relates to compositions, including cosmetic, pharmaceutical or homecare compositions, comprising at least one linear 2,3-alkanediol having a carbon chain of 5 to 13 atoms. The compositions may further comprise at least one linear 1,2-alkanediol having a carbon chain of 5 to 13 carbon atoms. Additionally, the present invention relates to the use of the compositions of the present invention for enhancing the antioxidative effect of an antioxidant, for improving the sensory properties, i.e. skin sensation, of a liquid lipophilic component, for sebum control, or for malodour management, or for modulating fragrance notes, or for modification of fragrance notes, or for suppression of fragrance notes, or for topical applications, or for coverage of the malodour of 1-octen-3-ol, or for masking insect alluring odours, or for repelling insects.
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公开(公告)号：US20230293407A1
公开(公告)日：2023-09-21
申请号：US18009295
申请日：2021-12-09
Applicant: Symrise AG
Inventor： Sabine Lange , Nikolas Bugdahn , Christin Koch
CPC classification number: A61K8/345 , A61K47/10 , A23L3/349 , A61K2800/5922 , A61K2800/524 , A61K2800/49 , A61K2800/10
Abstract: The present invention relates to a composition comprising or consisting of a synergistic combination of an effective amount of antimicrobial component and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols. Furthermore, the present invention relates to food, cosmetic or pharmaceutical preparations comprising said composition. Additionally, the present invention refers to the use of said composition for suppressing or inhibiting microorganism growth in food, a cosmetic or a pharmaceutical preparation or homecare product. Additionally, the present invention relates to the use of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols in an effective amount for boosting the efficacy of an antimicrobial active component. Finally, the present invention relates to a method for suppressing or inhibiting of microorganism growth in food, a cosmetic or a pharmaceutical preparation or homecare product.
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公开(公告)号：US20230118467A1
公开(公告)日：2023-04-20
申请号：US17909693
申请日：2020-03-06
Applicant: SYMRISE AG
Inventor： Martina Herrmann , Gerhard Schmaus , Nikolas Bugdahn , Dominik Stuhlmann , Katharina Striewe , Holger Joppe
IPC: A61K8/42 , A61K8/9794 , A61Q19/00 , A61Q19/02 , A61Q3/00 , A61Q5/00 , A61K31/164 , A61K36/899 , A23L33/105
Abstract: The present invention relates generally to: the cosmetic or pharmaceutical use of avenanthramide L or an oat extract comprising avenanthramide L; avenanthramide L or an oat extract comprising avenanthramide L as a neurokinin-1 receptor NK1R antagonist; and a method for preparing of preparing avenalumic acid and/or avenanthramide L.
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Patent Agency Ranking
公开(公告)号：US12049441B2
公开(公告)日：2024-07-30
申请号：US17799506
申请日：2020-02-18
Applicant: SYMRISE AG
Inventor： Nikolas Bugdahn , Angela Köckritz , Elka Kraleva , Reinhard Eckelt
CPC classification number: C07C5/31 , B01J29/7038 , C07C2529/70
Abstract: What is proposed is a continuous process for producing limonene which has the feature that beta-pinene or beta-pinene-containing starting materials are isomerized in a trickle-bed reactor in the presence of acid catalysts.
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公开(公告)号：US20230364027A1
公开(公告)日：2023-11-16
申请号：US18301051
申请日：2023-04-14
Applicant: Symrise AG
Inventor： Sabine Lange , Nikolas Bugdahn , Christin Koch
IPC: A61P31/04 , A61K31/047 , A23L33/10 , A61K45/06 , A61K31/164
CPC classification number: A61K31/047 , A23L33/127 , A61K31/164 , A61K45/06 , A61P31/04
Abstract: The present invention relates to a composition comprising or consisting of a synergistic combination of an effective amount of antimicrobial component and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols. Furthermore, the present invention relates to food, cosmetic or pharmaceutical preparations comprising said composition. Additionally, the present invention refers to the use of said composition for suppressing or inhibiting microorganism growth in food, a cosmetic or a pharmaceutical preparation. Additionally, the present invention relates to the use of 1,2-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols in an effective amount for boosting the efficacy of an anitmicrobial active component. Finally, the present invention relates to a method for suppressing or inhbiting of microorganism growth in food, a cosmetic or a pharmaceutical preparation.
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公开(公告)号：US20230293410A1
公开(公告)日：2023-09-21
申请号：US18301004
申请日：2023-04-14
Applicant: Symrise AG
Inventor： Nikolas Bugdahn , Sebastian Bruncke , Vanessa Schade , Sabine Lange
CPC classification number: A61K8/345 , A61K45/06 , A61K47/10 , A61Q19/00 , A61K2800/5922
Abstract: The present invention relates to a cosmetic or pharmaceutical, preferably dermatological, composition comprising or consisting of a liquid lipophilic component and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and the use of said compositions as a cosmetic, for personal care, as a pharmaceutical or for animal care. Additionally, the present invention relates to the use of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or of a mixture of two or more different specific alkanediols for improving the sensory properties, i.e. skin sensation, of a cosmetic or pharmaceutical composition upon topical application, or as silicone replacer.
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公开(公告)号：US20230293408A1
公开(公告)日：2023-09-21
申请号：US18009298
申请日：2021-12-09
Applicant: Symrise AG
Inventor： Nikolas Bugdahn , Sven Siegel , Sabine Lange , Dominik Stuhlmann
CPC classification number: A61K8/345 , A61K47/10 , A61K2800/5922 , A61K2800/524 , A61K2800/49 , A61K2800/10 , A61K2800/522
Abstract: The present invention is in the field of antioxidants and relates to cosmetic or pharmaceutical, preferably dermatological, compositions or homecare product comprising or consisting of a synergistic combination of a specific antioxidant and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and the use of said compositions as a cosmetic, for personal care, as a pharmaceutical or homecare product, in particular for scavenging reactive oxygen species (ROS), for inhibition matrix metalloproteinases expression and/or for inhibiting interleukin 8 (IL-8) secretion. Additionally, the present invention relates to the use of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols for enhancing the antioxidative effect of an antioxidant in a cosmetic or pharmaceutical, preferably dermatological, composition or homecare product, and/or for enhancing the antioxidative effect of a cosmetic or pharmaceutical, preferably dermatological, composition upon application.
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公开(公告)号：US20230248663A1
公开(公告)日：2023-08-10
申请号：US18301072
申请日：2023-04-14
Applicant: Symrise AG
Inventor： Nikolas Bugdahn , Sven Siegel , Sabine Lange , Dominik Stuhlmann
IPC: A61K31/047 , A61K31/355 , A61K47/22 , A61K47/10 , A61K31/23 , A61K31/222 , A61K31/375 , A61K47/14 , A61K47/08 , A61K8/67 , A61K8/34 , A61K8/37 , A61K8/39 , A61K8/35 , A61P17/18 , A61K31/167 , A61K31/4172 , A61K31/00 , A61K36/82 , A61K36/9068 , A61K47/18 , A61K8/42 , A61K8/49 , A61K47/46 , A61K8/9789 , A61K8/9794 , A61K31/07 , A61K31/198 , A61K8/43 , A61Q19/08 , A61Q19/00 , A61Q19/02 , A61Q5/00 , A61Q5/12 , A61Q15/00 , A61Q17/04 , A61Q9/02 , A61Q5/02
CPC classification number: A61K31/047 , A61K31/355 , A61K47/22 , A61K47/10 , A61K31/23 , A61K31/222 , A61K31/375 , A61K47/14 , A61K47/08 , A61K8/678 , A61K8/345 , A61K8/375 , A61K8/676 , A61K8/39 , A61K8/35 , A61P17/18 , A61K31/167 , A61K31/4172 , A61K31/658 , A61K36/82 , A61K36/9068 , A61K47/18 , A61K8/42 , A61K8/4946 , A61K8/347 , A61K47/46 , A61K8/9789 , A61K8/9794 , A61K31/07 , A61K8/671 , A61K31/198 , A61K47/183 , A61K8/43 , A61Q19/08 , A61Q19/007 , A61Q19/02 , A61Q19/002 , A61Q5/006 , A61Q5/12 , A61Q15/00 , A61Q17/04 , A61Q9/02 , A61Q5/02
Abstract: The present invention is in the field of antioxidants and relates to cosmetic or pharmaceutical, preferably dermatological, compositions or homecare product comprising or consisting of a synergistic combination of a specific antioxidant and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and the use of said compositions as a cosmetic, for personal care, as a pharmaceutical or homecare product, in particular for scavenging reactive oxygen species (ROS), for inhibition matrix metalloproteinases expression and/or for inhibiting interleukin 8 (IL-8) secretion. Additionally, the present invention relates to the use of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols for enhancing the antioxidative effect of an antioxidant in a cosmetic or pharmaceutical, preferably dermatological, composition or homecare product, and/or for enhancing the antioxidative effect of a cosmetic or pharmaceutical, preferably dermatological, composition upon application.
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