公开(公告)号：US09257709B2

公开(公告)日：2016-02-09

申请号：US13997545

申请日：2011-12-23

Applicant: Scott Sibbett ,  Carolin Lau ,  Gustavo Pio Marchesi Krall Ciniciato ,  Plamen Atanassov

Inventor： Scott Sibbett ,  Carolin Lau ,  Gustavo Pio Marchesi Krall Ciniciato ,  Plamen Atanassov

IPC: H01M8/16 ,  H01M8/04 ,  H01M8/00 ,  H01M8/02 ,  H01M8/08 ,  H01M8/24 ,  H01M8/10

CPC classification number: H01M8/04216 ,  H01M8/004 ,  H01M8/023 ,  H01M8/0247 ,  H01M8/0252 ,  H01M8/08 ,  H01M8/1009 ,  H01M8/16 ,  H01M8/2455 ,  Y02E60/527

Abstract: The present disclosure provides biological fuel cells comprising a paper-based fuel delivery layer which delivery fuel to the biological anode and cathode via capillary action and/or evaporation. In some embodiments the paper-based fuel delivery layer incorporates an outwardly extending fan-shaped region which enables a constant volumetric flow rate through the cell.

Abstract translation: 本公开提供了包括纸基燃料输送层的生物燃料电池，其通过毛细作用和/或蒸发将燃料输送到生物阳极和阴极。 在一些实施例中，基于纸的燃料输送层包括向外延伸的扇形区域，其能够通过电池的恒定体积流量。

公开(公告)号：US20110127165A1

公开(公告)日：2011-06-02

申请号：US13023807

申请日：2011-02-09

Applicant: Scott Sibbett

Inventor： Scott Sibbett

IPC: C25B7/00 ,  F16K11/20 ,  B82Y99/00

CPC classification number: G01N30/0005 ,  B01D67/0062 ,  G01N27/44756 ,  Y10S977/701 ,  Y10S977/72 ,  Y10S977/723 ,  Y10T137/87249 ,  G01N30/6095

Abstract: Disclosed herein are an apparatus and a method for separating molecules on the basis of size and or structure, and to a method of making the apparatus. Generally, the separation method includes passing a fluid comprising particles having different effective molecular diameters through a plurality of open, nanoscale channels disposed in surfaces of substrates. The method also includes obtaining a plurality of fractions of the passed fluid such that each of the fractions includes a major portion containing particles having similar size and shape and substantially free of particles having larger size and shape. The apparatus includes first and second substrates each of which has a surface containing a plurality of open, nanoscale channels disposed therein. The surfaces are bonded together such that each of the channels of the first substrate is in fluid communication with at least two of the channels of the second substrate and is misaligned relative to the channels of the second substrate. Interferometric lithography and anodic bonding or flip-chip bonding techniques can be used to make the apparatus.

Abstract translation: 本文公开了基于尺寸和/或结构分离分子的装置和方法，以及制造该装置的方法。 通常，分离方法包括使包含具有不同有效分子直径的颗粒的流体通过设置在基材表​​面中的多个开放的纳米级通道。 该方法还包括获得通过的流体的多个部分，使得每个级分包含主要部分，其含有具有相似尺寸和形状的颗粒，并且基本上不含具有较大尺寸和形状的颗粒。 该装置包括第一和第二基板，每个基板具有包含设置在其中的多个开放的纳米级通道的表面。 表面被接合在一起，使得第一基底的每个通道与第二基底的至少两个通道流体连通，并且相对于第二基底的通道不对准。 可以使用干涉光刻和阳极结合或倒装芯片接合技术来制造该装置。

公开(公告)号：US20100170798A1

公开(公告)日：2010-07-08

申请号：US12655423

申请日：2009-12-29

Applicant: Scott Sibbett ,  Dimiter Petsev

Inventor： Scott Sibbett ,  Dimiter Petsev

IPC: B01D57/02

CPC classification number: G01N27/44791 ,  B01L3/5027 ,  C25D17/002 ,  G01N27/44765

Abstract: A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrode positioned in the first channel and a second electrode positioned in the second channel wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the gel layer. In another embodiment, a microfluidic device includes a body having a surface with a channel separating two first reservoirs. One or more membranes are positioned on the surface covering a portion of the channel and a blank is positioned covering the channel and the one or more membranes. A second reservoir through the blank is in contact with the membrane, each second reservoir in communication with the channel via the membrane. A first electrode is positioned in the first reservoir and a second electrode is positioned in the second reservoir wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the membranes.

Abstract translation: 公开了具有一个或多个用于控制电解的膜的微流体装置和方法。 在一个实施例中，公开了一种微流体装置，其包括具有由凝胶层隔开的第一通道和第二通道的主体。 位于第一通道中的第一电极和位于第二通道中的第二电极，其中施加到第一和第二电极的电势通过凝胶层将电子从第一通道传递到第二通道。 在另一个实施例中，微流体装置包括具有表面的主体，该表面具有分隔两个第一储存器的通道。 一个或多个膜定位在覆盖通道的一部分的表面上，并且覆盖通道和一个或多个膜的空白被定位。 通过坯件的第二储存器与膜接触，每个第二储存器经由膜与通道连通。 第一电极定位在第一储存器中，第二电极定位在第二储存器中，其中施加到第一和第二电极的电势将电子从第一通道传递到通过膜的第二通道。

公开(公告)号：US20050217990A1

公开(公告)日：2005-10-06

申请号：US10815346

申请日：2004-03-31

Applicant: Scott Sibbett ,  Dimiter Petsev

Inventor： Scott Sibbett ,  Dimiter Petsev

IPC: B01L3/00 ,  B01L99/00 ,  C25B9/00 ,  C25D17/00 ,  G01N27/447

CPC classification number: G01N27/44791 ,  B01L3/5027 ,  C25D17/002 ,  G01N27/44765

Abstract: A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrodes positioned in the first channel and a second electrode positioned in the second channel wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the gel layer. In another embodiment, a microfluidic device includes a body having a surface with a channel separating two first reservoirs. One or more membranes are positioned on the surface covering a portion of the channel and a blank is positioned covering the channel and the one or more membranes. A second reservoir through the blank is in contact with the membrane, each second reservoir in communication with the channel via the membrane. A first electrode is positioned in the first reservoir and a second electrode is positioned in the second reservoir wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the membranes.

Abstract translation: 公开了具有一个或多个用于控制电解的膜的微流体装置和方法。 在一个实施例中，公开了一种微流体装置，其包括具有由凝胶层隔开的第一通道和第二通道的主体。 位于第一通道中的第一电极和位于第二通道中的第二电极，其中施加到第一和第二电极的电势将电子从第一通道传递到通过凝胶层的第二通道。 在另一个实施例中，微流体装置包括具有表面的主体，该表面具有分隔两个第一储存器的通道。 一个或多个膜定位在覆盖通道的一部分的表面上，并且覆盖通道和一个或多个膜的空白被定位。 通过坯件的第二储存器与膜接触，每个第二储存器经由膜与通道连通。 第一电极定位在第一储存器中，第二电极定位在第二储存器中，其中施加到第一和第二电极的电势将电子从第一通道传递到通过膜的第二通道。

公开(公告)号：US08088282B2

公开(公告)日：2012-01-03

申请号：US13023807

申请日：2011-02-09

Applicant: Scott Sibbett

Inventor： Scott Sibbett

IPC: B01D15/34 ,  B01D15/08

CPC classification number: G01N30/0005 ,  B01D67/0062 ,  G01N27/44756 ,  Y10S977/701 ,  Y10S977/72 ,  Y10S977/723 ,  Y10T137/87249 ,  G01N30/6095

Abstract: Disclosed herein are an apparatus and a method for separating molecules on the basis of size and or structure, and to a method of making the apparatus. Generally, the separation method includes passing a fluid comprising particles having different effective molecular diameters through a plurality of open, nanoscale channels disposed in surfaces of substrates. The method also includes obtaining a plurality of fractions of the passed fluid such that each of the fractions includes a major portion containing particles having similar size and shape and substantially free of particles having larger size and shape. The apparatus includes first and second substrates each of which has a surface containing a plurality of open, nanoscale channels disposed therein. The surfaces are bonded together such that each of the channels of the first substrate is in fluid communication with at least two of the channels of the second substrate and is misaligned relative to the channels of the second substrate. Interferometric lithography and anodic bonding or flip-chip bonding techniques can be used to make the apparatus.

Abstract translation: 本文公开了基于尺寸和/或结构分离分子的装置和方法，以及制造该装置的方法。 通常，分离方法包括使包含具有不同有效分子直径的颗粒的流体通过设置在基材表​​面中的多个开放的纳米级通道。 该方法还包括获得通过的流体的多个部分，使得每个级分包含主要部分，其含有具有相似尺寸和形状的颗粒，并且基本上不含具有较大尺寸和形状的颗粒。 该装置包括第一和第二基板，每个基板具有包含设置在其中的多个开放的纳米级通道的表面。 表面被接合在一起，使得第一基底的每个通道与第二基底的至少两个通道流体连通，并且相对于第二基底的通道不对准。 可以使用干涉光刻和阳极结合或倒装芯片接合技术来制造该装置。

公开(公告)号：US07976691B2

公开(公告)日：2011-07-12

申请号：US11711819

申请日：2007-02-28

Applicant: Scott Sibbett ,  Dimiter Petsev

Inventor： Scott Sibbett ,  Dimiter Petsev

IPC: G01N27/453

CPC classification number: G01N27/44791 ,  B01L3/5027 ,  C25D17/002 ,  G01N27/44765

Abstract: A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrode positioned in the first channel and a second electrode positioned in the second channel wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the gel layer. In another embodiment, a microfluidic device includes a body having a surface with a channel separating two first reservoirs. One or more membranes are positioned on the surface covering a portion of the channel and a blank is positioned covering the channel and the one or more membranes. A second reservoir through the blank is in contact with the membrane, each second reservoir in communication with the channel via the membrane. A first electrode is positioned in the first reservoir and a second electrode is positioned in the second reservoir wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the membranes.

Abstract translation: 公开了具有一个或多个用于控制电解的膜的微流体装置和方法。 在一个实施例中，公开了一种微流体装置，其包括具有由凝胶层隔开的第一通道和第二通道的主体。 位于第一通道中的第一电极和位于第二通道中的第二电极，其中施加到第一和第二电极的电势通过凝胶层将电子从第一通道传递到第二通道。 在另一个实施例中，微流体装置包括具有表面的主体，该表面具有分隔两个第一储存器的通道。 一个或多个膜定位在覆盖通道的一部分的表面上，并且覆盖通道和一个或多个膜的空白被定位。 通过坯件的第二储存器与膜接触，每个第二储存器经由膜与通道连通。 第一电极定位在第一储存器中，第二电极定位在第二储存器中，其中施加到第一和第二电极的电势将电子从第一通道传递到通过膜的第二通道。

公开(公告)号：US07906026B2

公开(公告)日：2011-03-15

申请号：US12315219

申请日：2008-12-01

Applicant: Scott Sibbett

Inventor： Scott Sibbett

IPC: B01D15/34 ,  B01D63/08

CPC classification number: G01N30/0005 ,  B01D67/0062 ,  G01N27/44756 ,  Y10S977/701 ,  Y10S977/72 ,  Y10S977/723 ,  Y10T137/87249 ,  G01N30/6095

Abstract: Disclosed herein are an apparatus and a method for separating molecules on the basis of size and or structure, and to a method of making the apparatus. Generally, the separation method includes passing a fluid comprising particles having different effective molecular diameters through a plurality of open, nanoscale channels disposed in surfaces of substrates. The method also includes obtaining a plurality of fractions of the passed fluid such that each of the fractions includes a major portion containing particles having similar size and shape and substantially free of particles having larger size and shape. The apparatus includes first and second substrates each of which has a surface containing a plurality of open, nanoscale channels disposed therein. The surfaces are bonded together such that each of the channels of the first substrate is in fluid communication with at least two of the channels of the second substrate and is misaligned relative to the channels of the second substrate. Interferometric lithography and anodic bonding or flip-chip bonding techniques can be used to make the apparatus.

Abstract translation: 本文公开了基于尺寸和/或结构分离分子的装置和方法，以及制造该装置的方法。 通常，分离方法包括使包含具有不同有效分子直径的颗粒的流体通过设置在基材表​​面中的多个开放的纳米级通道。 该方法还包括获得通过的流体的多个部分，使得每个级分包含主要部分，其含有具有相似尺寸和形状的颗粒，并且基本上不含具有较大尺寸和形状的颗粒。 该装置包括第一和第二基板，每个基板具有包含设置在其中的多个开放的纳米级通道的表面。 表面被接合在一起，使得第一基底的每个通道与第二基底的至少两个通道流体连通，并且相对于第二基底的通道不对准。 可以使用干涉光刻和阳极结合或倒装芯片接合技术来制造该装置。

公开(公告)号：US07402229B2

公开(公告)日：2008-07-22

申请号：US10815346

申请日：2004-03-31

Applicant: Scott Sibbett ,  Dimiter Petsev

Inventor： Scott Sibbett ,  Dimiter Petsev

IPC: G01N27/453 ,  B01L11/00

CPC classification number: G01N27/44791 ,  B01L3/5027 ,  C25D17/002 ,  G01N27/44765

Abstract: A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrode positioned in the first channel and a second electrode positioned in the second channel wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the gel layer. In another embodiment, a microfluidic device includes a body having a surface with a channel separating two first reservoirs. One or more membranes are positioned on the surface covering a portion of the channel and a blank is positioned covering the channel and the one or more membranes. A second reservoir through the blank is in contact with the membrane, each second reservoir in communication with the channel via the membrane. A first electrode is positioned in the first reservoir and a second electrode is positioned in the second reservoir wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the membranes.

Abstract translation: 公开了具有一个或多个用于控制电解的膜的微流体装置和方法。 在一个实施例中，公开了一种微流体装置，其包括具有由凝胶层隔开的第一通道和第二通道的主体。 位于第一通道中的第一电极和位于第二通道中的第二电极，其中施加到第一和第二电极的电势通过凝胶层将电子从第一通道传递到第二通道。 在另一个实施例中，微流体装置包括具有表面的主体，该表面具有分隔两个第一储存器的通道。 一个或多个膜定位在覆盖通道的一部分的表面上，并且覆盖通道和一个或多个膜的空白被定位。 通过坯件的第二储存器与膜接触，每个第二储存器经由膜与通道连通。 第一电极定位在第一储存器中，第二电极定位在第二储存器中，其中施加到第一和第二电极的电势将电子从第一通道传递到通过膜的第二通道。

公开(公告)号：US20060213776A1

公开(公告)日：2006-09-28

申请号：US11446326

申请日：2006-06-01

Applicant: Scott Sibbett ,  Dimiter Petsev

Inventor： Scott Sibbett ,  Dimiter Petsev

IPC: G01N27/00

CPC classification number: G01N27/44791 ,  B01L3/5027 ,  C25D17/002 ,  G01N27/44765

Abstract: A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrodes positioned in the first channel and a second electrode positioned in the second channel wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the gel layer. In another embodiment, a microfluidic device includes a body having a surface with a channel separating two first reservoirs. One or more membranes are positioned on the surface covering a portion of the channel and a blank is positioned covering the channel and the one or more membranes. A second reservoir through the blank is in contact with the membrane, each second reservoir in communication with the channel via the membrane. A first electrode is positioned in the first reservoir and a second electrode is positioned in the second reservoir wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the membranes.

Abstract translation: 公开了具有一个或多个用于控制电解的膜的微流体装置和方法。 在一个实施例中，公开了一种微流体装置，其包括具有由凝胶层隔开的第一通道和第二通道的主体。 位于第一通道中的第一电极和位于第二通道中的第二电极，其中施加到第一和第二电极的电势将电子从第一通道传递到通过凝胶层的第二通道。 在另一个实施例中，微流体装置包括具有表面的主体，该表面具有分隔两个第一储存器的通道。 一个或多个膜定位在覆盖通道的一部分的表面上，并且覆盖通道和一个或多个膜的空白被定位。 通过坯件的第二储存器与膜接触，每个第二储存器经由膜与通道连通。 第一电极定位在第一储存器中，第二电极定位在第二储存器中，其中施加到第一和第二电极的电势将电子从第一通道传递到通过膜的第二通道。

公开(公告)号：US20050126914A1

公开(公告)日：2005-06-16

申请号：US10868702

申请日：2004-06-14

Applicant: Scott Sibbett

Inventor： Scott Sibbett

IPC: G01N27/447 ,  G01N30/00 ,  G01N30/02 ,  G01N30/52 ,  G01N27/453

CPC classification number: G01N30/0005 ,  G01N27/44773 ,  G01N30/02 ,  G01N2030/0035 ,  G01N2030/528 ,  B01D15/34

Abstract: The present invention relates to a method of classifying charged molecules such as proteins for quantitative analysis. An analyte solution of the molecules is subjected to separational forces may be fluid drag and electrophoretic force in opposition. The analyte solution may be subjected to a two-phase process. The two-phase process may add both electrophoretic force based upon molecule charge, and differential mobility resistance based upon molecule mass and/or size.

Abstract translation: 本发明涉及用于定量分析的带电分子如蛋白质的分类方法。 分子的分析物溶液经受分离力可能是相反的流体阻力和电泳力。 分析物溶液可以进行两相处理。 两相方法可以基于分子电荷增加电泳力，并且基于分子质量和/或尺寸增加差动迁移率。