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786 条记录 (耗时 0.058 秒)

    Proxy-based push service
    13.
    发明授权
    Proxy-based push service 有权

    公开(公告)号：US09749435B2

    公开(公告)日：2017-08-29

    申请号：US13355441

    申请日：2012-01-20

    申请人： Li Li

    发明人： Li Li

    IPC分类号： H04W68/00 ,  H04L29/08

    CPC分类号： H04L67/26 ,  H04L67/28

    摘要： A method and apparatus to proxy notification service connections between a mobile client and a notification server. In one embodiment of the invention, a proxy receives a proxy setup request for the notification service from the mobile client. The proxy further establishes a notification connection with the notification server for the mobile client and maintains the notification connection without waking an application processor of the mobile client. The proxy receives a notification from the notification service and forwards the notification to the mobile client.

    Controlled color transition
    15.
    发明授权
    Controlled color transition 有权

    公开(公告)号：US09603218B1

    公开(公告)日：2017-03-21

    申请号：US14657966

    申请日：2015-03-13

    申请人： Christopher Lee Bohler ,  Li Li

    发明人： Christopher Lee Bohler ,  Li Li

    IPC分类号： H05B33/08

    CPC分类号： H05B33/0866 ,  H05B33/0851 ,  H05B33/0896

    摘要： A method of iteratively adjusting a color of light emitted by a light source includes setting a weighted target color to an initial color of a light emitted by a light source. The method further includes determining a target color of the light by a color controller to iteratively adjust a color of the light to the target color of the light. The method also includes determining an updated weighted target color as a combination of a portion of the weighted target color and a portion of the target color. The method further includes adjusting the color of the light by the color controller to the weighted target color.

    Protein and gene biomarkers for rejection of organ transplants
    16.
    发明授权
    Protein and gene biomarkers for rejection of organ transplants 有权
    用于器官移植排斥的蛋白质和基因生物标志物

    公开(公告)号：US09535075B2

    公开(公告)日：2017-01-03

    申请号：US13635667

    申请日：2011-03-25

    申请人： Minnie M. Sarwal ,  Tara Sigdel ,  Amit Kaushal ,  Li Li ,  Wenzhong Xiao ,  Atul J. Butte ,  Purvesh Khatri

    发明人： Minnie M. Sarwal ,  Tara Sigdel ,  Amit Kaushal ,  Li Li ,  Wenzhong Xiao ,  Atul J. Butte ,  Purvesh Khatri

    IPC分类号： C12Q1/68 ,  G01N33/68

    CPC分类号： G01N33/6893 ,  C12Q1/6809 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N2800/245

    摘要： Aspects of the present invention include methods for determining a transplant category of a subject having a transplant. Common mechanisms of rejection injury are uncovered across different tissue transplants, and provide a means to understand rational drug design. Various sources of tissues are examined form the patient for understanding AR mechanism (graft biopsy), as well as monitoring by minimal invasive means (blood) or non-invasive means (urine for the kidney allograft). For biomarker discovery different categories of markers are examined such as genes, proteins, peptides and antibodies. These biomarkers can help determine the subject's transplant category (e.g., acute allograft rejection (AR), stable allograft (STA), BK viremia, BK nephritis, drug toxicity or chronic allograft injury (CAI), and the like). Also provided are compositions, systems, kits and computer program products that find use in practicing the subject methods. The methods and compositions find use in a variety of applications.

    摘要翻译： 本发明的方面包括用于确定具有移植物的受试者的移植类别的方法。 排除损伤的常见机制在不同的组织移植中被发现，并且提供了解理性药物设计的手段。 从患者身上检查各种来源的组织，以了解AR机制（移植物活检），以及通过最小侵入性手段（血液）或非侵入性手段（尿同种异体移植物的尿液）进行监测。 对于生物标志物发现，检查不同类别的标记物，例如基因，蛋白质，肽和抗体。 这些生物标志物可以帮助确定受试者的移植类别（例如急性同种异体移植排斥（AR），稳定的同种异体移植物（STA），BK病毒血症，BK肾炎，药物毒性或慢性同种异体移植物损伤（CAI）等）。 还提供了用于实践主题方法的组合物，系统，试剂盒和计算机程序产品。 这些方法和组合物可用于各种应用。

    Extending processing capacity of server
    17.
    发明授权
    Extending processing capacity of server 有权
    扩展服务器的处理能力

    公开(公告)号：US09531636B2

    公开(公告)日：2016-12-27

    申请号：US13989927

    申请日：2011-11-24

    申请人： Li Li ,  Xin Hui Li ,  Wei Xue ,  Yi Xin Zhao

    发明人： Li Li ,  Xin Hui Li ,  Wei Xue ,  Yi Xin Zhao

    IPC分类号： G06F15/16 ,  H04L12/911 ,  G06F9/50

    CPC分类号： H04L47/70 ,  G06F9/505 ,  G06F2209/5017 ,  G06F2209/509

    摘要： Embodiments of the present invention relate to a method and apparatus for extending processing capacity of a server side. In one embodiment, there is provided a method of extending processing capacity of the server side, comprising: deciding a job to be offloaded from the server side; partitioning the job into one or more tasks; allocating the one or more tasks to one or more clients in response to http requests transmitted from the one or more clients; receiving, from the http requests transmitted from the one or more clients, responses of the one or more clients to the from the server side one or more tasks.

    摘要翻译： 本发明的实施例涉及一种用于扩展服务器侧的处理能力的方法和装置。 在一个实施例中，提供了一种扩展服务器侧的处理能力的方法，包括：从服务器侧确定要卸载的作业; 将作业分成一个或多个任务; 响应于从一个或多个客户端发送的http请求，将一个或多个任务分配给一个或多个客户机; 从所述一个或多个客户端发送的所述http请求中，从所述服务器端向所述一个或多个任务接收所述一个或多个客户端的响应。

    Biomarkers for determining an allograft tolerant phenotype
    18.
    发明授权
    Biomarkers for determining an allograft tolerant phenotype 有权
    用于确定同种异体移植耐受性表型的生物标志物

    公开(公告)号：US09290813B2

    公开(公告)日：2016-03-22

    申请号：US13512539

    申请日：2010-12-01

    申请人： Minnie M. Sarwal ,  Li Li ,  Samuel Strober

    发明人： Minnie M. Sarwal ,  Li Li ,  Samuel Strober

    IPC分类号： C12Q1/68 ,  C07H21/04

    CPC分类号： C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/106 ,  C12Q2600/158 ,  G01N33/6893 ,  G01N2800/245 ,  G01N2800/52

    摘要： Methods are provided for determining whether a subject has a graft tolerant phenotype. In practicing the subject methods, the expression level of one or more gene in a sample from the subject, e.g., a blood sample, is assayed to obtain a gene expression result, where the gene expression result includes a result for a biomarker of graft tolerance. The obtained gene expression result is then employed to determine whether the subject has a graft tolerant phenotype. Also provided are compositions, systems and kits that find use in practicing the subject methods. The methods and compositions find use in a variety of applications, including the determination of an immunosuppressive therapy regimen.

    摘要翻译： 提供了用于确定受试者是否具有移植物耐受性表型的方法。 在实施本发明方法中，测定来自受试者的样品（例如血液样品）中的一种或多种基因的表达水平以获得基因表达结果，其中基因表达结果包括用于接种耐药性的生物标志物的结果 。 然后使用获得的基因表达结果来确定受试者是否具有接受耐受性表型。 还提供了用于实践主题方法的组合物，系统和试剂盒。 该方法和组合物可用于各种应用，包括测定免疫抑制治疗方案。

    Determining location of mobile device
    19.
    发明授权
    Determining location of mobile device 有权
    确定移动设备的位置

    公开(公告)号：US09265024B2

    公开(公告)日：2016-02-16

    申请号：US14241702

    申请日：2012-06-27

    申请人： Li Li ,  Rui Xiong Tian ,  Wei Xue ,  Yi Xin Zhao

    发明人： Li Li ,  Rui Xiong Tian ,  Wei Xue ,  Yi Xin Zhao

    IPC分类号： H04W4/02 ,  H04W64/00 ,  G01S5/00 ,  G01S5/02

    CPC分类号： H04W64/00 ,  G01S5/0072 ,  G01S5/0284

    摘要： Embodiments of the present invention relate to a method and apparatus for determining the location of a mobile device. Specifically, the method comprises: receiving the location message from a neighboring mobile device, the location message comprising the location of the neighboring mobile device at the current time which is obtained by the neighboring mobile device through calculation utilizing signals received from satellites; and estimating the location of the mobile device at the current time based on stored locations of the mobile device at historical time, stored locations of the neighboring mobile device at the historical time, and the received location of the neighboring mobile device at the current time.

    摘要翻译： 本发明的实施例涉及一种用于确定移动设备的位置的方法和装置。 具体地说，该方法包括：从邻近的移动设备接收定位消息，所述位置消息包括当前时间由相邻移动设备通过利用从卫星接收的信号的计算获得的邻近移动设备的位置; 以及基于当前时间的移动设备的存储位置，在历史时刻的相邻移动设备的存储位置和当前时间的相邻移动设备的接收位置来估计当前时间的移动设备的位置。