摘要:
There is provided an industrial production method of an aminopyrrolidine derivative having chemokine receptor antagonist activity represented by the following formula, a synthetic intermediate thereof and a production method thereof: wherein R11 is H, C1-C6 alkyl or C2-C7 alkanoyl; R12, R14, R15, R16 and R17 are H, halogen, optionally halogenated C1-C6 alkyl, optionally halogenated C1-C6 alkoxy, hydroxyl or C2-C7 alkoxycarbonyl; R23, R24, R25 and R26 are H, halogen, optionally halogenated C1-C6 alkyl, optionally halogenated C1-C6 alkoxy or hydroxyl; and R3 is H or C1-C6 alkyl.
摘要翻译:提供了具有下式表示的趋化因子受体拮抗剂活性的氨基吡咯烷衍生物及其合成中间体及其制备方法的工业生产方法:其中R 11是H,C 1 C 6 -C 6烷基或C 2 -C 7烷酰基; R 12,R 14,R 15,R 16和R 17均为 H,卤素,任选卤代C 1 -C 6烷基,任意卤代C 1 -C 6烷氧基, 羟基或C 2 -C 7烷氧基羰基; R 23,R 24,R 25和R 26是H,卤素,任选卤代的C 1 -C 12烷基, C 1 -C 6烷基,任选卤代C 1 -C 6烷氧基或羟基; R 3是H或C 1 -C 6烷基。
摘要:
A benzimidazole derivative or its medically acceptable salt, represented by the following formula (1), that is a human chymase activity inhibitor capable of being applied clinically: wherein, R1 and R2 represent a hydrogen atom, an alkyl group or an alkoxy group, etc., A represents an alkylene group or an alkenylene group, E represents —COOR3, —SO3R3, —CONHR3 or —SO2NHR3, etc., G represents an alkylene group, M represents a single bond or —S(O)m—, J represents a heterocyclic group, and X represents —CH═ or a nitrogen atom.
摘要:
A diesel engine control system and control method capable of conducting accurate fuel injection unaffected by variations in injector performance caused by differences among individual injectors or change with aging. The diesel engine control system includes an injector for directly injecting fuel into a combustion chamber of a diesel engine, injection quantity controller for controlling fuel injection quantity by varying a period of electric current supply to the injector, estimator for estimating that an electric current supply period when a prescribed (stable) combustion state is obtained is the current supply period for injecting the amount of fuel required for the prescribed combustion state, and control data correcting device for correcting control data of the injection quantity controller based on the estimated current supply period.
摘要:
Disclosed is an apparatus for displaying a travel position, which, in carrying out steps of calculating X- and Y-coordinates of a current position of the moving body; renewably presents said current position on a road map indicated on a display screen; matches between a travel trace pattern formed by subsequent current positions and each road pattern on the road map; and puts the travel trace on the mated road pattern for correction of the current position of the moving body deviated from the road on the map, to determine what class of the road the moving body is running on, e.g. mountain road, superhighway or other ordinary road, and also changes the pattern matching condition to be adapted for the class of the road, as determined by a measured number of curves per unit of distance.
摘要:
There is disclosed an apparatus for displaying a current location of a running body in which a constantly changing location of the running body on a two-dimensional coordinates is successively computed, while detecting a running distance of the running body and a running direction of the same, and the current location of said running body is displayed renewally, in accordance with the data thus computed, on a display screen having a map previously displayed thereon. The apparatus comprises means for extracting a linear running portion from current location of the running body obtained by storing data of the current location, means for extracting a linear road portion from adjoining roads on the map which corresponds to the linear running portion extracted from the current location means for effecting matching between the extracted linear running portion and linear road portion, depending on their positional relationship and means for putting the current location, onto the road to which the matching has been effected.
摘要:
In a data conversion auxiliary module which is at a higher level than a file system in a disk management hierarchy, data stored in a storage medium, which becomes an object, is successively accessed. Then, a data conversion module captures a sector-unit access request to a device driver from the file system, converts data of a sector which is returned from the device driver, and writes the conversion data in the sector. Thereby, data conversion can be executed on a specific region of the storage medium, which is associated with the data in the storage medium.
摘要:
In a data conversion auxiliary module which is at a higher level than a file system in a disk management hierarchy, data stored in a storage medium, which becomes an object, is successively accessed. Then, a data conversion module captures a sector-unit access request to a device driver from the file system, converts data of a sector which is returned from the device driver, and writes the conversion data in the sector. Thereby, data conversion can be executed on a specific region of the storage medium, which is associated with the data in the storage medium.
摘要:
A display device for a vehicle is provided in which when a first image and a second image are projected from a single projection means (18) disposed in the interior of an instrument panel (13) toward the rear of the vehicle, the first image is shown on a transmission type first screen (16) provided on the instrument panel (13) so as to be visible from the vehicle compartment side, and the second image shown on a reflection type second screen (17) integrally provided beneath the first screen (16) is reflected by a reflection means (19) and projected on a front windshield (14) as a virtual image that is visible from the vehicle compartment side. Therefore, it is possible to display the first image and the second image on the instrument panel (13) and the front windshield (14), respectively, while using the single projection means (18), and not only can the weight, number of components, installation space and cost be reduced, but also it becomes easy for the first and second images to work in cooperation.
摘要:
An oblique forward vision device for making an area constituting a blind spot diagonally in front a vehicle visible to a driver. The device includes a first reflective mirror, provided on a reverse side of a door mirror oriented in a forward direction, for showing an area located diagonally in front of the vehicle, and a second reflective mirror, provided on an interior side of a front pillar, for reflecting light reflected off the first reflective mirror toward the driver. The driver looks at the second reflective mirror via the first reflective mirror and checks the blind spot diagonally in front of the vehicle.
摘要:
A vehicular integrated mirror system is provided that is supported on a vehicle body that includes a door, and has an outside mirror disposed outside a vehicle compartment and an interior mirror disposed within the vehicle compartment at a position in the proximity of the outside mirror so that, in cooperation with the outside mirror, a vehicle rear field of vision is obtained, wherein a mirror holder retaining the outside mirror and the inside mirror is swingably supported on mirror support means mounted on the vehicle body in order to change the reflection angle of the two mirror relative to a vehicle driver, and the reflection angle of the outside mirror and the inside mirror is changed by remote drive means that makes the mirror holder swing by remote operation. This enables the reflection angle of the outside mirror and the inside mirror to be remotely controlled.