公开(公告)号：USD325258S

公开(公告)日：1992-04-07

申请号：US454121

申请日：1989-12-21

Applicant: Joergen Andersen ,  Ib O. Sinnerup ,  Kristian J. Hvidtfeldt

Designer： Joergen Andersen ,  Ib O. Sinnerup ,  Kristian J. Hvidtfeldt

公开(公告)号：US4874501A

公开(公告)日：1989-10-17

申请号：US213243

申请日：1988-06-29

Applicant: Torben F. Christiansen ,  Finn Kokholm

Inventor： Torben F. Christiansen ,  Finn Kokholm

IPC: G01N27/404 ,  G01N27/27 ,  G01N27/30 ,  G01N27/40 ,  G01N27/416 ,  G01N27/49

CPC classification number: G01N27/404

Abstract: An electrochemical measuring electrode device (10) for polarographically measuring the partial pressure of oxygen in an electrolytic medium comprises a cathode (14) which is capable of reducing oxygen and defines an exposed oxygen-reducing cathode surface (20), an anode (18), which defines an exposed anode surface which is arranged relative to the exposed oxygen-reducing cathode surface so as to communicate electrolytically therewith through the electrolytic medium, and a membrane (24), which covers the exposed oxygen-reducing cathode surface and further defines an electrolyte chamber (22) in which the electrolytic medium is confined. In order to effectively promote the decomposition of H.sub.2 O.sub.2 generated in the electrolytic medium as an oxygen reduction intermediate and thereby reduce the response time of the electrode, a stable, non-biological catalytic means is provided catalytically communicating with the H.sub.2 O.sub.2. The stable, non-biological catalytic means is preferably constituted by platinum black particles which may be received by the membrane at a central region (42) thereof or alternatively be received by a support structure which may further constitute a covering of at least part of the membrane ( 24).

公开(公告)号：US4780192A

公开(公告)日：1988-10-25

申请号：US106959

申请日：1987-10-14

Applicant: Torben F. Christiansen ,  Finn Kokholm

Inventor： Torben F. Christiansen ,  Finn Kokholm

IPC: G01N27/404 ,  G01N27/27 ,  G01N27/30 ,  G01N27/40 ,  G01N27/416 ,  G01N27/49 ,  G01N27/54

CPC classification number: G01N27/404

Abstract: An electrochemical measuring electrode device (10) for polarographically measuring the partial pressure of oxygen in an electrolytic medium comprises a cathode (14) which is capable of reducing oxygen and defines an exposed oxygen-reducing cathode surface (20), an anode (18), which defines an exposed anode surface which is arranged relative to the exposed oxygen-reducing cathode surface so as to communicate electrolytically therewith through the electrolytic medium, and a membrane (24), which covers the exposed oxygen-reducing cathode surface and further defines an electrolyte chamber (22) in which the electrolytic medium is confined. In order to effectively promote the decomposition of H.sub.2 O.sub.2 generated in the electrolytic medium as an oxygen reduction intermediate and thereby reduce the response time of the electrode, a stable, non-biological catalytic means is provided catalytically communicating with the H.sub.2O 2. The stable, non-biological catalytic means is preferably constituted by platinum black particles which may be received by the membrane at a central region (42) thereof or alternatively be received by a support structure which may further constitute a covering of at least part of the membrane (24).The platinum black particles may be pressed into a foil material constituting a base material of the membrane or alternatively be applied in a suspension to the membrane whereupon the suspension is solidified.

Abstract translation: 用于极谱测量电解介质中的氧分压的电化学测量电极装置（10）包括能够还原氧并限定暴露的氧还原阴极表面（20）的阴极（14），阳极（18） ，其限定暴露的阳极表面，其相对于暴露的氧还原阴极表面布置以便通过电解介质与其电解连通;以及膜（24），其覆盖暴露的氧还原阴极表面，并进一步限定 电解质室（22），其中电解介质被限制。 为了有效地促进作为氧还原中间体的电解介质中产生的H 2 O 2的分解，从而减少电极的响应时间，提供了与H 2 O 2催化连通的稳定的非生物催化装置。 稳定的非生物催化装置优选由铂黑颗粒构成，其可以在膜的中心区域（42）处被膜接收，或者由支撑结构接收，该支撑结构可以进一步构成至少部分 膜（24）。 铂黑颗粒可以被压制成构成膜的基材的箔材料，或者以悬浮液施加到膜上，由此悬浮液固化。

公开(公告)号：US4415534A

公开(公告)日：1983-11-15

申请号：US308775

申请日：1981-10-05

Applicant: Finn C. Lundsgaard ,  Willy Andersen

Inventor： Finn C. Lundsgaard ,  Willy Andersen

IPC: G01N33/483 ,  G01N35/00 ,  G01N1/14

CPC classification number: G01N35/00

Abstract: An apparatus for analyzing biological liquids comprises a measuring block including measuring means for measuring characteristics of said liquids. The measuring block is mounted within a thermal shield or housing by means of a base member interconnecting a minor part of the inner wall of the housing and the measuring block so as to define a space between the inner walls of the housing and the measuring block, said space being filled with air or another medium having a poor thermal conductivity.The thermal shield or housing and the base member are made of a material with good thermal conductivity, and heating and/or cooling means are arranged in heat conductive contact with the said shield. The function of the heating and/or cooling means is controlled by a temperature sensor arranged in heat conductive contact with the measuring block, so as to maintain the temperature of said block at a substantially constant predetermined value.

Abstract translation: 用于分析生物液体的装置包括测量块，其包括用于测量所述液体的特性的测量装置。 测量块通过将壳体的内壁的小部分和测量块互相连接的基座构件安装在热屏蔽或壳体内，以便在壳体的内壁和测量块之间限定空间， 所述空间填充有空气或导热性差的介质。 热屏蔽或壳体和基座构件由具有良好导热性的材料制成，并且加热和/或冷却装置布置成与所述屏蔽件导热接触。 加热和/或冷却装置的功能由布置成与测量块导热接触的温度传感器控制，以便将所述块的温度保持在基本恒定的预定值。

公开(公告)号：US4324256A

公开(公告)日：1982-04-13

申请号：US20870

申请日：1979-03-15

Applicant: Peter K. R. Vesterager

Inventor： Peter K. R. Vesterager

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1477 ,  A61B5/1491 ,  G01N27/404 ,  G01N27/416

CPC classification number: A61B5/14539 ,  A61B5/1491 ,  G01N27/4162

Abstract: An electrode device for transcutaneous PCO.sub.2 measurement with a pH-sensitive measuring electrode behind a CO.sub.2 -permeable membrane, a reference electrode, and an electrical heating device for thermostating the measuring electrode and thermally stimulating the blood flow in the skin in the measuring area, the reference electrode being in direct heat-conductive contact with the electrical heating device and being designed so that it surrounds the measuring electrode. This permits compact design of the electrode in a very small size.

Abstract translation: 用于经皮PCO2测量的电极装置，其具有在CO 2可渗透膜后面的pH敏感测量电极，参考电极和用于恒温测量电极并热刺激测量区域中皮肤中的血流的电加热装置， 参考电极与电加热装置直接导热接触并且被设计成使其围绕测量电极。 这允许电极的紧凑设计非常小的尺寸。

公开(公告)号：US4308029A

公开(公告)日：1981-12-29

申请号：US147261

申请日：1980-05-05

Applicant: Ole Siggaard-Andersen

Inventor： Ole Siggaard-Andersen

IPC: G01N33/483 ,  G01N33/72 ,  G01N33/52

CPC classification number: G01N33/721 ,  Y10T436/205831 ,  Y10T436/25125

Abstract: Deoxygenation of a blood sample prior to determination of carbon monoxide hemoglobin is performed in a capillary tube containing a dry reducing agent. Ready for use capillary tubes having long storage life contain dry reducing agent and are sealed at both ends. Preferred capillary tubes contain mixture of reducing agent, pH buffer and anticoagulating agent present as a dry material on the interior tube wall.

Abstract translation: 在确定一氧化碳血红蛋白之前，血液样品的脱氧在含有干燥还原剂的毛细管中进行。 准备使用长寿命的毛细管含有干燥还原剂，并在两端密封。 优选的毛细管含有在内管壁上以干材料形式存在的还原剂，pH缓冲剂和抗凝剂的混合物。

公开(公告)号：US4274418A

公开(公告)日：1981-06-23

申请号：US45689

申请日：1979-06-05

Applicant: Peter K. R. Vesterager ,  Borge Jeppesen

Inventor： Peter K. R. Vesterager ,  Borge Jeppesen

IPC: A61B5/00 ,  A61B5/0408

CPC classification number: A61B5/14542 ,  A61B5/04082 ,  A61B5/1477 ,  A61B5/6833

Abstract: The invention relates to an electrochemical measuring device for transcutaneous measurement of arterial partial gas pressure, especially partial pressure of oxygen or carbon dioxide. The measuring device comprises an annular mounting member having a skin contacting surface adapted to be fastened to the skin surface of a patient, and a sensor of the type having a semi-permeable membrane adapted to be releasably connected to the mounting member. In the connected position of the sensor, the membrane is axially spaced from the skin contacting surface of the mounting member so that the membrane, the inner wall of the annular mounting member, and the skin surface define a measuring chamber which may be filled with a gel or another medium, if desired.

Abstract translation: 本发明涉及用于经皮测量动脉部分气体压力，特别是氧气或二氧化碳分压的电化学测量装置。 测量装置包括环形安装构件，其具有适于紧固到患者皮肤表面的皮肤接触表面，以及具有适于可释放地连接到安装构件的半透膜的类型的传感器。 在传感器的连接位置，膜与安装构件的皮肤接触表面轴向间隔开，使得膜，环形安装构件的内壁和皮肤表面限定测量室，其可以填充有 凝胶或另一种介质。

公开(公告)号：US4163734A

公开(公告)日：1979-08-07

申请号：US866951

申请日：1978-01-05

Applicant: Soren K. Sorensen ,  Carl C. Holbek

Inventor： Soren K. Sorensen ,  Carl C. Holbek

IPC: A61B5/00 ,  B01J13/02 ,  B65D65/40 ,  G01N33/483 ,  G01N33/96 ,  C09K3/00

CPC classification number: G01N33/96 ,  A61B5/1495 ,  B01J13/025 ,  A61B2560/0233 ,  G01N2496/10 ,  G01N2496/15 ,  G01N2496/70 ,  Y10T436/102499 ,  Y10T436/108331

Abstract: A stable synthetic water based reference liquid for quality control and/or calibration of blood gas measuring equipment, said liquid being enclosed in a gas-tight container and containing HCO.sub.3.sup.- ions, H.sup.+ ions, CO.sub.2 gas, and O.sub.2 gas plus an additional pH buffer system different from the pH buffer system constituted by the HCO.sub.3.sup.- ions and the CO.sub.2 gas, said liquid showing, at a fixed temperature, known pH, pCO.sub.2 and pO.sub.2 values, said liquid additionally containing oxygen reversibly contained in a dispersed non-proteinaceous organic substance which shows higher solubility for oxygen than does water, and, optionally, a coloring component showing maximum or significant absorption at about 500 nm, said organic substance being(a) a water-insoluble organic substance in which O.sub.2 l is soluble to an extent of at least 12% by volume at 1 atmosphere oxygen pressure and 25.degree. C., said water-insoluble substance being a liquid of lipoid character emulsified in a liquid-in-water type emulsion, in the water base of the reference liquid, or a solid suspended in the water base of the reference liquid, or(b) an oxygen complex-forming metal organic compound of a transition group metal dissolved in the water base of the reference liquid, the stability constant of the oxygen complex of which metal organic compound is in the range of 1.times.10.sup.3 to 10.sup.5.5.

Abstract translation: 一种稳定的合成水基参比液，用于血气测量设备的质量控制和/或校准，所述液体封闭在气密容器中并含有HCO3-离子，H +离子，CO2气体和O2气体以及另外的pH缓冲液 系统不同于由HCO 3 - 离子和CO 2气体构成的pH缓冲系统，所述液体在固定温度下显示已知pH，pCO 2和pO 2值，所述液体还含有可逆地包含在分散的非蛋白质有机物质中的氧 其显示出比水更高的氧气溶解度，以及任选的在约500nm处显示最大或显着吸收的着色组分，所述有机物质是（A）其中O 2的水不溶性有机物质可溶于 在1个大气压和25℃下至少12体积％，所述水不溶性物质是在水包油型乳液中在水中乳化的脂质的液体 参考液的碱或悬浮在参考液的水基中的固体，或（B）在参考液的水基中溶解的过渡金属组分的氧化复合金属有机化合物，稳定性恒定 金属有机化合物的氧气复合物的范围为1×103〜105.5。

公开(公告)号：US4151108A

公开(公告)日：1979-04-24

申请号：US806837

申请日：1977-06-15

Applicant: Soren K. Sorensen ,  Carl C. Holbek

Inventor： Soren K. Sorensen ,  Carl C. Holbek

IPC: A61B5/00 ,  B01J13/02 ,  G01N33/483 ,  G01N33/96 ,  C09K3/00

CPC classification number: G01N33/96 ,  A61B5/1495 ,  B01J13/025 ,  A61B2560/0233 ,  G01N2496/10 ,  G01N2496/15 ,  G01N2496/70 ,  Y10T428/2984 ,  Y10T428/2987 ,  Y10T436/102499 ,  Y10T436/108331

Abstract: A reference liquid for the calibration and/or quality control of blood gas analyzers. The reference liquid comprises an aqueous phase and either polymer-coated microcapsules containing at least one organic substance functioning as oxygen carrier, or porous particles of a solid substance functioning as oxygen carrier. An example of the polymer-coated microcapsules is nylon-coated microcapsules containing a mixture of perfluorotributyl amine and isooctane. An example of the porous particles of a solid substance is particles of porous silicone rubber.

Abstract translation: 用于血气分析仪校准和/或质量控制的参考液。 参考液体包含水相和包含至少一个作为氧载体起作用的有机物质的聚合物涂覆的微胶囊，或作为氧载体起作用的固体物质的多孔颗粒。 聚合物涂覆的微胶囊的实例是含有全氟三丁胺和异辛烷的混合物的尼龙涂覆的微胶囊。 固体物质的多孔颗粒的实例是多孔硅橡胶的颗粒。

公开(公告)号：US3943917A

公开(公告)日：1976-03-16

申请号：US576676

申请日：1975-05-12

Applicant: Ebbe Johansen

Inventor： Ebbe Johansen

IPC: A61B5/15 ,  A61B5/00

CPC classification number: A61B5/15003 ,  A61B5/150213 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150389 ,  A61B5/150519 ,  A61B5/153 ,  A61B5/150259

Abstract: The invention relates to a method for collecting a blood sample from a blood vessel, such as an artery, by means of a syringe, preferably of the type having a piston displaceably mounted within a cylinder which is provided with a hollow needle. Before the needle is inserted in the blood vessel from which the blood sample is to be collected the piston is displaced to a retracted position, and the cylinder space defined by the piston is vented to the atmosphere. The invention also relates to a blood sampling syringe having means for venting the cylinder space to the atmosphere in a retracted position of the syringe piston.

Abstract translation: 本发明涉及一种通过注射器从诸如动脉的血管收集血液样本的方法，该注射器优选地具有可移动地安装在设置有空心针的圆筒内的活塞的类型。 在将针插入要从其中收集血液样本的血管中之前，活塞移动到缩回位置，并且由活塞限定的气缸空间排放到大气中。 本发明还涉及一种采血注射器，其具有用于在注射器活塞的缩回位置将气缸空间排放到大气中的装置。