公开(公告)号：US5525518A

公开(公告)日：1996-06-11

申请号：US720530

申请日：1991-06-21

申请人： Finn C. Lundsgaard ,  Niels-Henrik Jensen ,  Willy Andersen

发明人： Finn C. Lundsgaard ,  Niels-Henrik Jensen ,  Willy Andersen

IPC分类号： G01N33/49 ,  G01N21/03 ,  G01N21/11 ,  G01N21/25 ,  G01N21/27 ,  G01N21/31 ,  G01N21/64 ,  G01N21/76 ,  G01N21/77 ,  G01N21/80 ,  G01N21/84 ,  G01N33/48 ,  G01N33/497 ,  G01N33/84 ,  G01N35/00 ,  G01N35/10 ,  G01N33/50

CPC分类号： G01N21/03 ,  G01N21/251 ,  G01N21/255 ,  G01N21/276 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/78 ,  G01N33/4925 ,  G01N33/497 ,  G01N2021/0346 ,  G01N2021/036 ,  G01N2021/0364 ,  G01N2021/3148 ,  G01N2021/3166 ,  G01N2021/6417 ,  G01N2021/6432 ,  G01N2021/6439 ,  G01N2021/7786 ,  G01N2021/8405 ,  G01N2035/00306 ,  G01N2035/00316 ,  G01N2035/1062 ,  G01N21/05 ,  G01N21/80 ,  G01N2201/0407 ,  G01N2201/0476 ,  G01N2201/0618 ,  G01N2201/1288

摘要： A method of photometric in vitro determination of at least one blood gas parameter in a sample of whole blood. The whole blood sample is obtained by connecting an at least partially transparent sample container to an in vivo locality and transferring whole blood into the sample container, then breaking the connection. The sample container is arranged in an optical system which has a radiation source and a means for detecting radiation to locate the sample container between the radiation source and the radiation detection means. Radiation is transmitted to the sample from the radiation source and radiation emitted from the sample is transmitted to the radiation detection means. The detected radiation is used to determine the blood gas parameter of the sample. A system for use in this method has a radiation source, a radiation detection means, an at least partially transparent sample container, and a sample container station.

摘要翻译： PCT No.PCT / DK89 / 00302 Sec。 371日期1991年6月21日 102（e）1991年6月21日PCT 1989年12月21日PCT PCT。 公开号WO90 / 07106 日期：1990年6月28日。全血样品中至少一种血气参数的光度测定方法。 通过将至少部分透明的样品容器连接到体内局部并将全血转移到样品容器中，然后断开连接而获得全血样品。 样品容器布置在具有辐射源的光学系统和用于检测辐射的装置以将样品容器定位在辐射源和辐射检测装置之间的光学系统中。 辐射从辐射源发射到样品，并且从样品发射的辐射被传输到辐射检测装置。 检测到的辐射用于确定样品的血气参数。 用于该方法的系统具有辐射源，辐射检测装置，至少部分透明的样品容器和样品容器台。

公开(公告)号：US5366903A

公开(公告)日：1994-11-22

申请号：US199858

申请日：1994-02-22

申请人： Finn C. Lundsgaard ,  Niels-Henrik Jensen ,  Willy Andersen

发明人： Finn C. Lundsgaard ,  Niels-Henrik Jensen ,  Willy Andersen

IPC分类号： G01N33/49 ,  G01N21/03 ,  G01N21/11 ,  G01N21/25 ,  G01N21/27 ,  G01N21/31 ,  G01N21/64 ,  G01N21/76 ,  G01N21/77 ,  G01N21/80 ,  G01N21/84 ,  G01N33/48 ,  G01N33/497 ,  G01N33/84 ,  G01N35/00 ,  G01N35/10

CPC分类号： G01N21/03 ,  G01N21/251 ,  G01N21/255 ,  G01N21/276 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/78 ,  G01N33/4925 ,  G01N33/497 ,  G01N2021/0346 ,  G01N2021/036 ,  G01N2021/0364 ,  G01N2021/3148 ,  G01N2021/3166 ,  G01N2021/6417 ,  G01N2021/6432 ,  G01N2021/6439 ,  G01N2021/7786 ,  G01N2021/8405 ,  G01N2035/00306 ,  G01N2035/00316 ,  G01N2035/1062 ,  G01N21/05 ,  G01N21/80 ,  G01N2201/0407 ,  G01N2201/0476 ,  G01N2201/0618 ,  G01N2201/1288

摘要： A sampling device for photometric determination of the content of an analyte in a sample of whole blood has at least one measuring chamber having two wall parts, at least one wall part being locally transparent, at least one wall part being sufficiently deformable to facilitate displacement of the whole blood sample from the measuring chamber. The measuring chamber also contains a transparent body having a radiation transmission characteristic dependent upon the concentration of a predetermined analyte in the whole blood sample. The sample device is employed in an analyzer for photometric determination of the content of an analyte in a sample of whole blood and in a method of photometric in vitro determination of the content of an analyte in a sample of whole blood. In the method, a sample of whole blood is transferred directly from an in vivo locality to the sampling device, the measuring chamber therein is deformed in a controlled manner to substantially drain the whole blood from the measuring chamber, radiation is transmitted through the substantially drained measuring chamber, detected, and the analyte content determined.

摘要翻译： 用于对全血样品中的分析物的含量进行光度测定的取样装置具有至少一个具有两个壁部分的测量室，至少一个壁部分局部透明，至少一个壁部分具有足够的可变形性， 来自测量室的全血样品。 测量室还包含具有取决于全血样品中预定分析物浓度的辐射透射特性的透明体。 样品装置用于用于光度测定全血样品中的分析物的含量的分析仪中，以及全血样品中分析物的含量的光度测定方法。 在该方法中，将全血样品直接从体内局部转移到采样装置，其中的测量室以受控的方式变形，从而从测量室基本上排出全部血液，辐射通过基本排出的 测量室，检测，并确定分析物含​​量。

公开(公告)号：US5288646A

公开(公告)日：1994-02-22

申请号：US720531

申请日：1991-06-21

申请人： Finn C. Lundsgaard ,  Niels-Henrik Jensen ,  Willy Andersen

发明人： Finn C. Lundsgaard ,  Niels-Henrik Jensen ,  Willy Andersen

IPC分类号： G01N33/49 ,  G01N21/03 ,  G01N21/11 ,  G01N21/25 ,  G01N21/27 ,  G01N21/31 ,  G01N21/64 ,  G01N21/76 ,  G01N21/77 ,  G01N21/80 ,  G01N21/84 ,  G01N33/48 ,  G01N33/497 ,  G01N33/84 ,  G01N35/00 ,  G01N35/10

CPC分类号： G01N21/03 ,  G01N21/251 ,  G01N21/255 ,  G01N21/276 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/78 ,  G01N33/4925 ,  G01N33/497 ,  G01N2021/0346 ,  G01N2021/036 ,  G01N2021/0364 ,  G01N2021/3148 ,  G01N2021/3166 ,  G01N2021/6417 ,  G01N2021/6432 ,  G01N2021/6439 ,  G01N2021/7786 ,  G01N2021/8405 ,  G01N2035/00306 ,  G01N2035/00316 ,  G01N2035/1062 ,  G01N21/05 ,  G01N21/80 ,  G01N2201/0407 ,  G01N2201/0476 ,  G01N2201/0618 ,  G01N2201/1288

摘要： A sampling device for photometric determination of the content of an analyte in a sample of whole blood has at least one measuring chamber having locally transparent wall parts, at least one wall part being sufficiently deformable to facilitate displacement of the whole blood sample from the measuring chamber, with a transparent body having a radiation transmission characteristic dependent upon the concentration of a predetermined analyte in the whole blood sample disposed between the wall parts. The sampling device is employed in an analyzer for photometric determination of the content of analyte in a sample of whole blood and in a method of photometric in vitro determination of the content of an analyte in a sample of whole blood. In the method, a sample of whole blood is transferred directly from an in vivo locality to the sampling device, the measuring chamber therein is deformed in a controlled manner to substantially drain the whole blood from the measuring chamber, radiation is transmitted through the substantially drained measuring chamber, detected, and the analyte content determined. A measuring chamber for photometric determination of an analyte in a sample of whole blood has locally transparent wall parts, at least one being sufficiently deformable to facilitate displacement of the whole blood sample from the measuring chamber, and a transparent body disposed between the wall parts. The measuring chamber is employed in an analyzer and in a method for the photometric determination of an analyte in a sample of whole blood.

摘要翻译： PCT No.PCT / DK89 / 00301 Sec。 371日期1991年6月21日 102（e）1991年6月21日PCT 1989年12月21日PCT PCT。 公开号WO90 / 07109 日本1990年6月28日。用于光度测定全血样品中分析物含量的采样装置具有至少一个具有局部透明壁部分的测量室，至少一个壁部分可充分变形， 来自测量室的全血样本，具有取决于设置在壁部之间的全血样品中的预定分析物的浓度的透射特性的透明体。 采样装置用于测量全血样品中分析物含量的光度测定仪和全血样品中分析物含量的光度测定方法。 在该方法中，将全血样品直接从体内局部转移到采样装置，其中的测量室以受控的方式变形，从而从测量室基本上排出全部血液，辐射通过基本排出的 测量室，检测，并确定分析物含​​量。 用于光度测定全血样品中的分析物的测量室具有局部透明的壁部分，至少一个可充分变形以促进全血样品从测量室排出，以及设置在壁部之间的透明体。 测量室用于分析仪和全血样品中的分析物的光度测定方法。

公开(公告)号：US4415534A

公开(公告)日：1983-11-15

申请号：US308775

申请日：1981-10-05

申请人： Finn C. Lundsgaard ,  Willy Andersen

发明人： Finn C. Lundsgaard ,  Willy Andersen

IPC分类号： G01N33/483 ,  G01N35/00 ,  G01N1/14

CPC分类号： G01N35/00

摘要： An apparatus for analyzing biological liquids comprises a measuring block including measuring means for measuring characteristics of said liquids. The measuring block is mounted within a thermal shield or housing by means of a base member interconnecting a minor part of the inner wall of the housing and the measuring block so as to define a space between the inner walls of the housing and the measuring block, said space being filled with air or another medium having a poor thermal conductivity.The thermal shield or housing and the base member are made of a material with good thermal conductivity, and heating and/or cooling means are arranged in heat conductive contact with the said shield. The function of the heating and/or cooling means is controlled by a temperature sensor arranged in heat conductive contact with the measuring block, so as to maintain the temperature of said block at a substantially constant predetermined value.

摘要翻译： 用于分析生物液体的装置包括测量块，其包括用于测量所述液体的特性的测量装置。 测量块通过将壳体的内壁的小部分和测量块互相连接的基座构件安装在热屏蔽或壳体内，以便在壳体的内壁和测量块之间限定空间， 所述空间填充有空气或导热性差的介质。 热屏蔽或壳体和基座构件由具有良好导热性的材料制成，并且加热和/或冷却装置布置成与所述屏蔽件导热接触。 加热和/或冷却装置的功能由布置成与测量块导热接触的温度传感器控制，以便将所述块的温度保持在基本恒定的预定值。

公开(公告)号：US06605471B1

公开(公告)日：2003-08-12

申请号：US09194372

申请日：1999-04-21

申请人： Finn C. Lundsgaard ,  Henrik Kagenow ,  Willy Andersen ,  Peter Aage Frischauf

发明人： Finn C. Lundsgaard ,  Henrik Kagenow ,  Willy Andersen ,  Peter Aage Frischauf

IPC分类号： G01N2111

CPC分类号： G01N35/025 ,  G01N33/4925 ,  G01N2035/00277 ,  G01N2035/00752 ,  G01N2035/041 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/113332 ,  Y10T436/114165 ,  Y10T436/25

摘要： The present invention relates to a method for determining at least one parameter of samples of physiological liquids, to test devices which may be used in the method, to a holder comprising a plurality of such test devices, and to a measuring apparatus adapted to accommodate the holder and to be used in the method and to a system comprising the apparatus and the holder.

摘要翻译： 本发明涉及一种用于确定生理液体样本的至少一个参数的方法，将可用于该方法的装置测试到包括多个这样的测试装置的保持器以及适于容纳 并且用于该方法和包括该装置和该保持器的系统。

公开(公告)号：US5564419A

公开(公告)日：1996-10-15

申请号：US269950

申请日：1994-06-30

申请人： Finn C. Lundsgaard ,  Niels-Henrik Jensen ,  Willy Andersen

发明人： Finn C. Lundsgaard ,  Niels-Henrik Jensen ,  Willy Andersen

IPC分类号： G01N21/03 ,  G01N21/25 ,  G01N21/27 ,  G01N21/31 ,  G01N21/64 ,  G01N21/80 ,  G01N21/84 ,  G01N33/49 ,  G01N33/497 ,  G01N35/00 ,  G01N35/10 ,  A61B5/00

CPC分类号： G01N33/4925 ,  G01N21/251 ,  G01N21/255 ,  G01N21/276 ,  G01N21/6428 ,  G01N33/497 ,  G01N2021/036 ,  G01N2021/3148 ,  G01N2021/3166 ,  G01N2021/6432 ,  G01N2021/6439 ,  G01N2021/8405 ,  G01N2035/00306 ,  G01N2035/00316 ,  G01N2035/1062 ,  G01N21/80 ,  G01N2201/0407 ,  G01N2201/0476 ,  G01N2201/0618 ,  G01N2201/1288 ,  Y10T436/207497

摘要： In a method of photometric in vitro determination of the content of oxygen in a blood sample, a blood sample is transferred directly from an in vivo locality to an at least partially transparent sample container of a sampling device. The sample container has a measuring chamber containing a luminophor, the luminescence of which is quenched in the presence of oxygen. The luminophor is excited by irradiation with radiation from a radiation source. The luminescence emitted by the excited luminophor is detected by a radiation detector and the oxygen content determined on the basis of the radiation detected by the radiation detector. A sampling device and a system for photometric in vitro determination of oxygen in a blood sample are also described.

摘要翻译： 在光度测定血液样品中的氧含量的方法中，将血液样品直接从体内局部转移到采样装置的至少部分透明的样品容器中。 样品容器具有含有发光体的测量室，其发光在氧气存在下淬火。 发光体被来自辐射源的辐射照射而激发。 由激发的发光体发射的发光由辐射检测器检测，并且基于由辐射检测器检测的辐射确定的氧含量。 还描述了用于血液样品中的氧的体外测定的取样装置和系统。