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公开(公告)号:US11819845B2
公开(公告)日:2023-11-21
申请号:US17469656
申请日:2021-09-08
Applicant: TECAN TRADING AG
Inventor: Thomas Perroud , Dan Tran , Daniel Hoffmeyer , Tiffany Lay , Manjeet Dhindsa
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01L3/508 , B01L3/50273 , B01L3/502761 , B01L3/502792 , B01L2200/025 , B01L2200/0668 , B01L2300/0816 , B01L2300/123 , B01L2400/043 , B01L2400/0427
Abstract: A digital microfluidics system with electrodes attached to a substrate and covered by a hydrophobic surface and a control unit for manipulating liquid droplets by electrowetting, providing in close proximity to electrodes a magnetic conduit for directing a magnetic field of a backing magnet to the first hydrophobic surface, providing on the hydrophobic surface a liquid droplet that has magnetically responsive beads moving by electrowetting the liquid droplet with the magnetically responsive beads until a part of which is placed atop of the magnetic conduit, actuating the backing magnet of the magnetic conduit and attracting/concentrating magnetically responsive beads while actuating the backing magnet, moving by electrowetting the liquid droplet with decreased number of magnetically responsive beads away from the specific magnetic conduit. Also disclosed are a method for suspending magnetically responsive beads in liquid portions or droplets in digital microfluidics and a disposable cartridge to carry out the methods.
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公开(公告)号:USD1002866S1
公开(公告)日:2023-10-24
申请号:US29805771
申请日:2021-08-30
Applicant: Tecan Trading AG
Designer: Marina Knoppke , Sven Pflumm , Claudio Bohli
Abstract: FIG. 1 is a perspective view of a pipetting tip box according to a First Embodiment of our new design;
FIG. 2 is a front view thereof;
FIG. 3 is a rear view thereof;
FIG. 4 is a left-side view thereof;
FIG. 5 is a right-side view thereof;
FIG. 6 is an enlarged top plan view thereof;
FIG. 7 is a bottom plan view thereof;
FIG. 8 is a perspective view of a pipetting tip box according to a Second Embodiment our new design;
FIG. 9 is a front view thereof;
FIG. 10 is a rear view thereof;
FIG. 11 is a left-side view thereof;
FIG. 12 is a right-side view thereof;
FIG. 13 is an enlarged top plan view thereof; and,
FIG. 14 is a bottom plan view thereof.
The broken lines depict portions of the pipetting tip box that form no part of the claimed design.-
公开(公告)号:US11666914B2
公开(公告)日:2023-06-06
申请号:US15975283
申请日:2018-05-09
Applicant: TECAN TRADING AG
Inventor: Patrick Kinney , Sujata Iyer , Tin Ngo , Jennifer Ji , Marta Matvienko , Tiffany Ding (Lay)
IPC: B01L3/00
CPC classification number: B01L3/502761 , B01L3/502792 , B01L2300/123 , B01L2400/0427
Abstract: A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge contains an internal gap with at least one hydrophobic surface for enabling an electrowetting induced movement of a microfluidic droplet that has magnetic beads and further has a bead accumulation zone, into which the microfluidic droplet is transferable by electrowetting force and the magnetic beads are exposable to a magnetic force of a bead manipulation magnet. The internal gap has a bead extraction opening adjacent to the bead accumulation zone. The bead extraction opening provides a passage from the gap to an exterior space of the cartridge and is configured to removably receive the bead manipulation magnet for enabling an extraction of the magnetic beads from the microfluidic droplet by a removal of the bead manipulation magnet.
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公开(公告)号:US20230152338A1
公开(公告)日:2023-05-18
申请号:US17980009
申请日:2022-11-03
Applicant: TECAN TRADING AG
Inventor: Philipp OTT , Yves WURMITZER , Volfgang VILAJ
CPC classification number: G01N35/00029 , G01N1/34 , G01N35/1009
Abstract: Some embodiments are directed to a method for tracking lysis progress in an automated lysing device. For example, the lysing device may be configured to execute multiple iterations of lysing at a defined location on the tissue section and imaging the defined location on the tissue section using a camera. From the images a lysing parameter may be determined to improve lysing.
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公开(公告)号:US11630117B2
公开(公告)日:2023-04-18
申请号:US16213787
申请日:2018-12-07
Applicant: TECAN TRADING AG
Inventor: Ronan Leboudec
Abstract: A laboratory automation device (10) includes a plurality of device components (14, 16), which are controlled by digital control commands (26). The digital control commands (26) are generated by a controller (20) of the laboratory automation device (10) from assay definition data (38) defining an assay procedure for the laboratory automation device (10).
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公开(公告)号:US11525727B2
公开(公告)日:2022-12-13
申请号:US17258596
申请日:2019-07-09
Applicant: TECAN TRADING AG
Inventor: Philipp Ott , Luca Frei , Pascal Dieterich
IPC: G01F23/26 , G01F23/263
Abstract: A device for controlling an optical recognition unit with the help of a capacitive filling level measurement in liquid containers having a sensor with a measuring electrode, a conductive base plate suitable for arranging at least one liquid container or a carrier unit having at least one receptacle for receiving a liquid container, a sensor electronics unit that is connected to the measuring electrode and the base plate adapted to determine a capacitance between the measuring electrode and base plate, an evaluation unit, and a control unit for controlling the optical recognition unit, is disclosed.
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公开(公告)号:US20210402415A1
公开(公告)日:2021-12-30
申请号:US17294499
申请日:2018-11-20
Applicant: TECAN TRADING AG
Inventor: Fred SCHINZEL
Abstract: A centrifugal processing unit for directing the movement of substances within a sample processing cartridge has a rotor with an accommodation for receiving the sample processing cartridge, the accommodation only allowing a free pivoting motion of the cartridge about a respective pivot axis, wherein each pivot axis is orthogonal to the rotor axis and to a respective force vector of a centrifugal force, a rotor drive to create the centrifugal force, a blocking element, allowing the free pivoting motion of the cartridge in a release position and preventing the free pivoting motion in a blocking position, wherein the blocking element is arranged on the rotor spaced apart above the accommodation is disclosed.
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18.
公开(公告)号:US20210402402A1
公开(公告)日:2021-12-30
申请号:US17470669
申请日:2021-09-09
Applicant: TECAN TRADING AG
Inventor: Manjeet DHINDSA , Khushroo GANDHI
IPC: B01L3/00
Abstract: A cartridge configured to control and manipulate liquids and to be positioned at a cartridge accommodation site of a digital microfluidics system is disclosed. The digital microfluidics system has a number or array of individual electrodes attached to a first substrate or PCB, a central control unit in operative contact with individual electrodes for controlling selection and for providing a number of individual electrodes that define a path of individual electrodes with voltage for manipulating liquid portions or liquid droplets by electrowetting, and a cartridge accommodation site that is configured for taking up the cartridge.
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公开(公告)号:US11207693B2
公开(公告)日:2021-12-28
申请号:US16765112
申请日:2018-10-25
Applicant: TECAN TRADING AG
Inventor: Nicolas Cors , Martin Kuster
Abstract: A gripper having a mechanical coupling that can be connected to a pipetting tube, at least one fluid channel extends from the coupling and a negative pressure can be transmitted, the gripper having at least one suction cup that is connected to the coupling through the at least one fluid channel as a result of which the negative pressure can be transmitted from the coupling to the at least one suction cup, and the at least one suction cup in the intended use position of the gripper is aligned such that a rim of a suction cup of the at least one suction cup is aligned in a substantially vertical plane.
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20.
公开(公告)号:US11161108B2
公开(公告)日:2021-11-02
申请号:US16307215
申请日:2017-07-21
Applicant: TECAN TRADING AG
Inventor: Philipp Ott
Abstract: A pipetting device having a lube has an opening al one end for suctioning or discharging a sample fluid and can be operatively connected to a pressure generation device at the other end, a first electrode is formed on the pipetting device and forms a measuring capacitor together with a second electrode formed by at least one part of the sample fluid that can be received in the tube and that measuring capacitor is operatively connected to a measuring unit, and the measuring unit is designed to determine a volume of the suctioned or discharged sample fluid according to the capacity of the measuring capacitor, as well as having a first electrical contact that is designed to create an electrical connection with the working fluid, the first electrical contact can be electrically connected to the measuring unit via a low-resistance converter circuit.
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