公开(公告)号：US10696939B2

公开(公告)日：2020-06-30

申请号：US16079482

申请日：2016-04-22

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander Govyadinov ,  Erik D. Torniainen ,  David P. Markel ,  Pavel Kornilovich

IPC: B01L3/00 ,  C12M1/00 ,  C12N1/06

Abstract: In an example implementation, a method of cell lysis includes moving cell fluid from a first reservoir through a microfluidic channel toward a second reservoir, activating a lysing element multiple times as a cell from the cell fluid passes through the microfluidic channel, and moving lysate fluid that results from the activating through the microfluidic channel and into the second reservoir.

公开(公告)号：US20200147605A1

公开(公告)日：2020-05-14

申请号：US16616947

申请日：2017-07-18

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Jeremy Harlan Donaldson ,  Stephen Lee Frey ,  Pavel Kornilovich ,  Alexander Govyadinov

IPC: B01L3/00

Abstract: A sample test device is provided that includes a body having an insertion surface spaced apart from a distal end portion and a fluid manipulating assembly disposed in the distal end portion. A mixing receptacle is defined in the fluid manipulating assembly and provides a volume to mix a test mixture. A plunger is disposed in the body and creates a positive air pressure in the mixing receptacle when inserted into the body. A test die is disposed in the fluid manipulation assembly and a fluid path extends from the mixing receptacle to the test die. Activation of the plunger creates a positive pressure in the mixing receptacle to force the test mixture to flow from the mixing receptacle to the test die.

公开(公告)号：US20200003601A1

公开(公告)日：2020-01-02

申请号：US16462071

申请日：2017-02-23

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Ning GE ,  Chien-Hua Chen ,  Alexander Govyadinov

IPC: G01F23/24 ,  G01F23/00 ,  B41J2/175 ,  B23K26/364

Abstract: A fluid reservoir may include a number of metal traces along a wall of the fluid reservoir, and a number of fuse circuits along a length of the metal traces. Each of the fuse circuits may include a fuse along a length of a respective metal trace, and a number of parasitic resistive elements in parallel to the fuse. The parasitic resistive elements reduce current flow through the fuse in the presence of a fluid contained within the fluid reservoir.

公开(公告)号：US20190128248A1

公开(公告)日：2019-05-02

申请号：US16094433

申请日：2016-07-22

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander Govyadinov

IPC: F04B19/04 ,  B01L3/00 ,  F04B17/00 ,  F04B17/03 ,  F04B19/00 ,  F04B19/24

Abstract: According to an example, a microfluidic device may include a transport channel having an inlet and an outlet and a plurality of pump loops extending along the transport channel. Each of the plurality of pump loops may include a first branch, a second branch, and a connecting section connecting the first branch and the second branch. The first branch may include a first opening and the second branch may include a second opening, in which the first opening and the second opening are in direct fluid communication with the transport channel. The pump loops may also each include an actuator positioned in the first branch, in which the actuators in the pump loops are to be activated to induce a traveling wave that is to transport the fluid through the transport channel from the inlet to the outlet.

公开(公告)号：US20190030890A1

公开(公告)日：2019-01-31

申请号：US16146812

申请日：2018-09-28

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander Govyadinov ,  Chris Bakker

IPC: B41J2/14 ,  B41J2/045 ,  B41J2/135

Abstract: A fluid ejection device includes a fluid slot, a plurality of fluid ejection chambers communicated with the fluid slot, a plurality of drop ejecting elements one of each within one of the fluid ejection chambers, a plurality of fluid circulation channels each communicated with the fluid slot and one or more of the fluid ejection chambers, and a plurality of fluid circulating elements each communicated with one or more of the fluid circulation channels. The fluid circulating elements are to provide intermittent circulation of fluid from the fluid slot through the one or more of the fluid circulation channels and the one or more of the fluid ejection chambers.

公开(公告)号：US20190001695A1

公开(公告)日：2019-01-03

申请号：US16125701

申请日：2018-09-08

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander Govyadinov ,  Adam L. Ghozeil ,  Boon Bing Ng ,  Patrick Leonard ,  Raymond Connolly

IPC: B41J2/175 ,  B41J2/045 ,  B41J2/14 ,  B41J2/18

CPC classification number: B41J2/17566 ,  B41J2/04541 ,  B41J2/0458 ,  B41J2/1404 ,  B41J2/14072 ,  B41J2/14153 ,  B41J2/175 ,  B41J2/18 ,  B41J2002/14467 ,  B41J2202/11 ,  B41J2202/12

Abstract: A print head has a fluid slot and a sensing chamber having a first port connected to the fluid slot and a second port. The sensing chamber contains an ink level sensor. A circulation passage extends from the fluid slot and is fluidly coupled to the second port. A fluid pump circulates fluid through the circulation passage.

公开(公告)号：US10118389B2

公开(公告)日：2018-11-06

申请号：US15521848

申请日：2014-10-31

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Alexander Govyadinov ,  Chris Bakker

IPC: B41J2/14 ,  B41J2/045 ,  B41J2/135

Abstract: A fluid ejection device includes a fluid slot, a plurality of fluid ejection chambers communicated with the fluid slot, a plurality of drop ejecting elements one of each within one of the fluid ejection chambers, a plurality of fluid circulation channels each communicated with the fluid slot and one or more of the fluid ejection chambers, and a plurality of fluid circulating elements each communicated with one or more of the fluid circulation channels. The fluid circulating elements are to provide intermittent circulation of fluid from the fluid slot through the one or more of the fluid circulation channels and the one or more of the fluid ejection chambers.

公开(公告)号：US20180230518A1

公开(公告)日：2018-08-16

申请号：US15955364

申请日：2018-04-17

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Pavel Kornilovich ,  Erik D. Tornianinen ,  Alexander Govyadinov ,  David P. Markel

IPC: C12Q1/686

CPC classification number: C12Q1/686 ,  B01L3/50273 ,  B01L7/525 ,  B01L2200/10 ,  B01L2300/0681 ,  B01L2300/0867 ,  B01L2300/1827

Abstract: In one embodiment, a polymerase chain reaction (PCR) system includes a mixture chamber, a denature chamber, an annealing chamber, an extension chamber, and a product chamber, that are fluidically coupled to one another through a plurality of microfluidic channels. An inertial pump is associated with each microfluidic channel, and each inertial pump includes a fluid actuator integrated asymmetrically within its associated microfluidic channel. The fluid actuators are capable of selective activation to circulate fluid between the chambers in a controlled cycle.

公开(公告)号：US20180215146A1

公开(公告)日：2018-08-02

申请号：US15747966

申请日：2015-10-30

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Nicholas Matthew Cooper McGuinness ,  Alexander Govyadinov ,  Chris Bakker ,  Lawrence H. White ,  Paul A. Richards

IPC: B41J2/14

CPC classification number: B41J2/1404 ,  B41J2/14056 ,  B41J2202/11 ,  B41J2202/12

Abstract: According to an example, a fluid ejection device may include a fluid feed slot, a plurality of fluid ejection chambers in fluid communication with the fluid feed slot, a plurality of drop ejecting elements, in which a drop ejecting element of the plurality of drop ejecting elements is positioned within each of the plurality of fluid ejection chambers, a fluid circulation channel in fluid communication at a first end of the fluid circulation channel with the fluid feed slot and in fluid communication at multiple second ends of the fluid circulation channel with the plurality of fluid ejection chambers, and a fluid circulating element within the fluid circulation channel. The fluid ejection device may also include a bubble dissipating structure positioned within the fluid circulation channel outside of the plurality of fluid ejection chambers.

公开(公告)号：US20180214866A1

公开(公告)日：2018-08-02

申请号：US15748456

申请日：2016-01-08

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Erik D Torniainen ,  Alexander Govyadinov ,  Pavel Kornilovich ,  David P Markel

IPC: B01L3/00 ,  C12M3/06 ,  C12M1/34

CPC classification number: B01L3/50273 ,  B01L3/502784 ,  B01L7/52 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/087 ,  B01L2300/0896 ,  B01L2300/1827 ,  B01L2400/0442 ,  B01L2400/0481 ,  C12M23/16 ,  C12M41/12 ,  C12Q1/686

Abstract: Examples include polymerase chain reaction (PCR) devices. Example PCR devices comprise a fluid input, a fluid output, and a set of microfluidic channels that fluidly connect the fluid input and the fluid output. Each microfluidic channel comprises a reaction chamber, and examples further comprise at least one heating element, where the at least one heating element is positioned in the reaction chamber of each microfluidic channel. The at least one heating element is to heat fluid in the reaction chamber of each fluid channel, and the at least one heating element is to pump fluid to the reaction chamber and from the reaction chamber of each microfluidic channel.