公开(公告)号：US20190033313A1

公开(公告)日：2019-01-31

申请号：US15579078

申请日：2016-06-02

Applicant: University of Florida Research Foundation, Inc.

Inventor： NIKOLAUS GRAVENSTEIN ,  CHRISTIANA M. SHAW ,  MICHAEL T. COSTANZO ,  RICK YOST ,  CANDICE Z. ULMER ,  LOUIS SEARCY

IPC: G01N33/574

Abstract: The present disclosure provides methods and systems for detecting melanoma in a host. The methods include non-invasive methods of detecting melanoma and methods and systems for providing a molecular signature and/or melanoma biomarker signature for a host.

公开(公告)号：US20190027303A1

公开(公告)日：2019-01-24

申请号：US15653805

申请日：2017-07-19

Applicant: Futurewei Technologies, Inc. ,  University of Florida Research Foundation, Inc.

Inventor： Huan Zhang ,  Heping Dai ,  Shuo Wang

IPC: H01F27/38

Abstract: A device comprises a magnetic core comprising a first leg and a second leg formed by a first magnetic component and a second magnetic component, wherein a first gap and a second gap are placed between the first magnetic component and the second magnetic component and are in the first leg and the second leg, respectively, a first winding wound around the first leg in a counter-clockwise direction and a second winding wound around the second leg in a clockwise direction.

公开(公告)号：US20190019967A1

公开(公告)日：2019-01-17

申请号：US16122511

申请日：2018-09-05

Applicant: University of Florida Research Foundation, Inc.

Inventor： Jiangeng Xue

IPC: H01L51/42 ,  H01L51/00 ,  G03F7/00

Abstract: Embodiments of the invention pertain to the use of alloyed semiconductor nanocrystals for use in solar cells. The use of alloyed semiconductor nanocrystals offers materials that have a flexible stoichiometry. The alloyed semiconductor may be a ternary semiconductor alloy, such as AxB1-xC or AB1-yCy, or a quaternary semiconductor alloy, such as AxByC1-x-yD, AxB1-xCyD1-y or ABxCyD1-x-y (where A, B, C, and D are different elements). In general, alloys with more than four elements can be used as well, although it can be much harder to control the synthesis and quality of such materials. Embodiments of the invention pertain to solar cells having a layer incorporating two or more organic materials such that percolated paths for one or both molecular species are created. Specific embodiments of the invention pertain to a method for fabricating nanostructured bulk heterojunction that facilitates both efficient exciton diffusion and charge transport. Embodiments of the subject invention pertain to a solar cell having an architecture that allows for efficient harvesting of solar energy. The organic solar cell architecture can incorporate a host/guest (or matrix/dopant) material system that utilizes the long diffusion lengths for triplet excitons without compromising light absorption efficiency.

公开(公告)号：US10181598B2

公开(公告)日：2019-01-15

申请号：US14987878

申请日：2016-01-05

Applicant: University of Florida Research Foundation, Inc.

Inventor： Kevin S. Jones ,  Nicholas G. Rudawski ,  Shadi Al Khateeb

IPC: H01M4/04 ,  H01M4/66 ,  H01M4/58 ,  H01M10/052 ,  H01M4/02

Abstract: Embodiments of the present disclosure provide for cathodes having a metal sulfide thin layer, devices including cathodes, lithium ion batteries including cathodes, methods of making cathodes, and the like.

公开(公告)号：US10174042B2

公开(公告)日：2019-01-08

申请号：US15348756

申请日：2016-11-10

Applicant: University of Florida Research Foundation, Inc. ,  STC.UNM

Inventor： David G. Whitten ,  Kirk S. Schanze ,  Anand Parthasarathy ,  Eunkyung Ji ,  Motokatsu Ogawa ,  Thomas S. Corbitt ,  Dimitri Dascier ,  Ying Wang ,  Linnea K. Ista ,  Eric H. Hill

IPC: C07D487/08 ,  C07C217/14 ,  C07C309/11 ,  C07C217/20 ,  C07C309/24 ,  C07D333/16 ,  C08G61/02 ,  C08G75/00 ,  C08G61/12

Abstract: The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.

公开(公告)号：US20180371433A1

公开(公告)日：2018-12-27

申请号：US15766447

申请日：2016-10-19

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Inventor： Julie A. MAUPIN-FURLOW ,  Nathaniel L. HEPOWIT ,  Lana McMILLAN

IPC: C12N9/14 ,  C12Q1/42

Abstract: The invention pertains to a PPA from a microorganism belonging to the family Halobacteriaceae (HPPA), for example, a PPA from Haloferax volcanii. The HPPA provided by the invention is soluble, thermostable and active at high concentrations of salt and/or organic solvent. An embodiment of the invention provides a method of increasing the rate of a reaction by adding an HPPA to the reaction mixture, wherein the reaction produces PPi, for example, an enzymatic reaction, and wherein the reaction is carried out at moderately high temperature and/or low water activity. Further embodiments of the invention provide an assay to detect the PPi released during a reaction which produces PPi by adding an HPPA to convert the PPi in to Pi and measuring the resultant Pi. The invention further pertains to an assay to monitor a reaction which produces PPi in the presence or the absence of an HPPA.

公开(公告)号：US10160946B2

公开(公告)日：2018-12-25

申请号：US14917035

申请日：2014-09-12

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Inventor： Mina-Elraheb Saad Hanna ,  Juan Claudio Nino

IPC: C12N5/00 ,  C12M3/00 ,  C12M1/26 ,  C12M1/00 ,  C12M1/12 ,  C12M1/42

Abstract: Disclosed herein is a tissue harvester comprising a substrate having an airfoil shape; and a textured surface disposed upon the substrate, where the textured surface comprises a spatial array of nanometer or micrometer sized pillars of varying cross-sections. Disclosed herein too is method comprising disposing upon a substrate a textured surface; where the substrate has an airfoil shape and where the textured surface where the textured surface comprises nanometer or micrometer sized pillars; contacting the tissue harvester with biological cells whose proliferation under different conditions is desired; and disposing the tissue harvester in a flow field such that cells disposed on the tissue harvester at different locations may experience different flow fields.

公开(公告)号：US20180353768A1

公开(公告)日：2018-12-13

申请号：US16061848

申请日：2017-01-05

Applicant: University of Florida Research Foundation, Inc.

Inventor： Jon P. Dobson ,  Josephine Allen

IPC: A61N2/02 ,  A61N2/06 ,  C12N15/115 ,  A61N2/00

CPC classification number: A61N2/02 ,  A61N2/002 ,  A61N2/06 ,  C12N15/115 ,  C12N2310/16 ,  C12N2310/351

Abstract: Embodiments of the present disclosure provide for magnetic particle conjugates, methods of making the magnetic particle conjugates, methods of using magnetic particle conjugates, and the like.

公开(公告)号：US20180333481A1

公开(公告)日：2018-11-22

申请号：US15762108

申请日：2016-09-25

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Inventor： JANET K. YAMAMOTO

IPC: A61K39/21 ,  A61K9/00 ,  C07K14/005 ,  A61P31/14 ,  A61P31/18

Abstract: The subject invention concerns methods and materials for inducing an immune response in an animal or person against an immunodeficiency virus, such as HIV, SIV, or FIV. In one embodiment, a method of the invention comprises administering one or more antigens and/or immunogens to the person or animal wherein the antigen and/or immunogen comprises one or more evolutionarily conserved epitopes of immunodeficiency viruses. In one embodiment, the epitope is one that is conserved between HIV and FIV.

公开(公告)号：US10130098B1

公开(公告)日：2018-11-20

申请号：US15497468

申请日：2017-04-26

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Inventor： Donald L. Hopkins

IPC: C12N1/20 ,  A01N63/00

Abstract: The subject invention pertains to methods for reducing the incidence or severity of citrus greening in desirable plants, such as orange trees, grapefruit trees, lime trees, lemon trees and the like.