公开(公告)号：US07372556B2

公开(公告)日：2008-05-13

申请号：US11264076

申请日：2005-10-31

Applicant: Roger W Engelbart ,  Reed Hannebaum ,  Tim Pollock ,  Sam Orr ,  Jeff Putnam ,  Eric Rector

Inventor： Roger W Engelbart ,  Reed Hannebaum ,  Tim Pollock ,  Sam Orr ,  Jeff Putnam ,  Eric Rector

IPC: G01N11/00

CPC classification number: G01N21/88 ,  B29C70/382 ,  B29C70/386 ,  G01N2021/8472 ,  G01N2021/8867 ,  G01N2201/0635 ,  G01N2201/0636

Abstract: A system and method of inspecting material laid by a material placement machine. Light is directed onto the material in a direction essentially normal to the material to illuminate a section of the material. Laser energy is projected onto the section at an angle predetermined to reveal inconsistencies in the section. This system provides improved illumination for material widths exceeding six inches and is scalable for inspecting various material widths.

Abstract translation: 一种材料放置机器放置材料的检查系统和方法。 光以基本上垂直于材料的方向被引导到材料上以照射材料的一部分。 激光能量以预定的角度投影到部分上，以显示该部分中的不一致。 该系统为超过6英寸的材料宽度提供改进的照明，并且可扩展以用于检查各种材料宽度。

公开(公告)号：US07298477B1

公开(公告)日：2007-11-20

申请号：US11506639

申请日：2006-08-18

Applicant: Brian T. Cunningham ,  Peter Y. Li ,  Frank DiFilippi

Inventor： Brian T. Cunningham ,  Peter Y. Li ,  Frank DiFilippi

IPC: G01J3/28

CPC classification number: G01N21/253 ,  B01L3/5085 ,  B01L2300/0645 ,  B01L2300/0654 ,  B01L2300/0829 ,  G01N21/4788 ,  G01N21/7743 ,  G01N33/54373 ,  G01N2201/0635 ,  G01N2201/08 ,  G01N2201/0833 ,  G01N2201/0846 ,  G01N2201/1248 ,  G02B5/1809 ,  G02B5/1814 ,  G02B21/06

Abstract: Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light source. A first optical fiber is coupled to the light source and illuminates the biosensor. A second optical fiber detects a wavelength reflected from the biosensor. A spectrometer determines spectra of a reflected signal from the biosensor.

公开(公告)号：US20070090309A1

公开(公告)日：2007-04-26

申请号：US11256904

申请日：2005-10-24

Applicant: Qingying Hu ,  Kevin Harding ,  Joseph Ross ,  Xiaoping Qian

Inventor： Qingying Hu ,  Kevin Harding ,  Joseph Ross ,  Xiaoping Qian

IPC: G01N21/88

CPC classification number: G01B11/25 ,  F01D21/003 ,  F01D25/00 ,  G01N21/21 ,  G01N21/55 ,  G01N21/8806 ,  G01N21/9515 ,  G01N2201/0635

Abstract: A method for inspecting an object using a structured light measurement system that includes a light source for projecting light onto a surface of the object and an imaging sensor for receiving light reflected from the object. The method includes determining a position of at least one of the light source and the imaging sensor with respect to the object based on at least one of a three-dimensional model of the object and a three-dimensional model of the structured light measurement system.

Abstract translation: 一种用于使用结构化光测量系统检查物体的方法，该系统包括用于将光投射到物体的表面上的光源和用于接收从物体反射的光的成像传感器。 该方法包括基于物体的三维模型和结构光测量系统的三维模型中的至少一个来确定光源和成像传感器中的至少一个相对于对象的位置。

公开(公告)号：US20070041012A1

公开(公告)日：2007-02-22

申请号：US11404485

申请日：2006-04-13

Applicant: Brian Cunningham ,  Peter Li ,  Frank DeFilippi

Inventor： Brian Cunningham ,  Peter Li ,  Frank DeFilippi

IPC: G01J3/28

CPC classification number: G01N21/253 ,  B01L3/5085 ,  B01L2300/0645 ,  B01L2300/0654 ,  B01L2300/0829 ,  G01N21/4788 ,  G01N21/7743 ,  G01N33/54373 ,  G01N2201/0635 ,  G01N2201/08 ,  G01N2201/0833 ,  G01N2201/0846 ,  G01N2201/1248 ,  G02B5/1809 ,  G02B5/1814 ,  G02B21/06

Abstract: Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light source. A first optical fiber is coupled to the light source and illuminates the biosensor. A second optical fiber detects a wavelength reflected from the biosensor. A spectrometer determines spectra of a reflected signal from the biosensor.

公开(公告)号：US07148964B2

公开(公告)日：2006-12-12

申请号：US11404162

申请日：2006-04-13

Applicant: Brian T. Cunningham ,  Peter Y. Li ,  Frank DiFilippi

Inventor： Brian T. Cunningham ,  Peter Y. Li ,  Frank DiFilippi

IPC: G01J3/28

CPC classification number: G01N21/253 ,  B01L3/5085 ,  B01L2300/0645 ,  B01L2300/0654 ,  B01L2300/0829 ,  G01N21/4788 ,  G01N21/7743 ,  G01N33/54373 ,  G01N2201/0635 ,  G01N2201/08 ,  G01N2201/0833 ,  G01N2201/0846 ,  G01N2201/1248 ,  G02B5/1809 ,  G02B5/1814 ,  G02B21/06

Abstract: Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light source. A first optical fiber is coupled to the light source and illuminates the biosensor. A second optical fiber detects a wavelength reflected from the biosensor. A spectrometer determines spectra of a reflected signal from the biosensor.

公开(公告)号：US20060199259A1

公开(公告)日：2006-09-07

申请号：US11406148

申请日：2006-04-18

Applicant: Anthony Cerrone ,  Edward Lakatos ,  Michael Gambini ,  Eugene Young ,  Susan Stone ,  Judith Atwood ,  John Atwood

Inventor： Anthony Cerrone ,  Edward Lakatos ,  Michael Gambini ,  Eugene Young ,  Susan Stone ,  Judith Atwood ,  John Atwood

IPC: C12M1/34

CPC classification number: G01N21/6428 ,  B01L3/5085 ,  B01L7/52 ,  B01L2200/10 ,  B01L2300/0654 ,  B01L2300/0663 ,  B01L2300/1811 ,  C12Q1/686 ,  C12Q2545/101 ,  G01N21/274 ,  G01N21/645 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2021/6463 ,  G01N2021/6482 ,  G01N2201/0245 ,  G01N2201/06113 ,  G01N2201/0628 ,  G01N2201/0635 ,  G01N2201/0636 ,  G01N2201/068 ,  C12Q2563/107

Abstract: An instrument for monitoring replication of DNA is provided.

Abstract translation: 提供了一种用于监测DNA复制的工具。

公开(公告)号：US20060181704A1

公开(公告)日：2006-08-17

申请号：US11404162

申请日：2006-04-13

Applicant: Brian Cunningham ,  Peter Li ,  Frank DeFilippi

Inventor： Brian Cunningham ,  Peter Li ,  Frank DeFilippi

IPC: G01J3/28

CPC classification number: G01N21/253 ,  B01L3/5085 ,  B01L2300/0645 ,  B01L2300/0654 ,  B01L2300/0829 ,  G01N21/4788 ,  G01N21/7743 ,  G01N33/54373 ,  G01N2201/0635 ,  G01N2201/08 ,  G01N2201/0833 ,  G01N2201/0846 ,  G01N2201/1248 ,  G02B5/1809 ,  G02B5/1814 ,  G02B21/06

Abstract: Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light source. A first optical fiber is coupled to the light source and illuminates the biosensor. A second optical fiber detects a wavelength reflected from the biosensor. A spectrometer determines spectra of a reflected signal from the biosensor.

公开(公告)号：US20060181703A1

公开(公告)日：2006-08-17

申请号：US11404158

申请日：2006-04-13

Applicant: Brian Cunningham ,  Peter Li ,  Frank DeFilippi

Inventor： Brian Cunningham ,  Peter Li ,  Frank DeFilippi

IPC: G01J3/28

CPC classification number: G01N21/253 ,  B01L3/5085 ,  B01L2300/0645 ,  B01L2300/0654 ,  B01L2300/0829 ,  G01N21/4788 ,  G01N21/7743 ,  G01N33/54373 ,  G01N2201/0635 ,  G01N2201/08 ,  G01N2201/0833 ,  G01N2201/0846 ,  G01N2201/1248 ,  G02B5/1809 ,  G02B5/1814 ,  G02B21/06

Abstract: Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light source. A first optical fiber is coupled to the light source and illuminates the biosensor. A second optical fiber detects a wavelength reflected from the biosensor. A spectrometer determines spectra of a reflected signal from the biosensor.

公开(公告)号：US07008789B2

公开(公告)日：2006-03-07

申请号：US10216620

申请日：2002-08-09

Applicant: Michael R. Gambini ,  Susan Atwood Stone, legal representative ,  Judith K. Atwood, legal representative ,  Eugene F. Young ,  Edward J. Lakatos ,  Anthony L. Cerrone

Inventor： John G. Atwood, deceased

IPC: C12M1/34

CPC classification number: G01N21/6428 ,  B01L3/5085 ,  B01L7/52 ,  B01L2200/10 ,  B01L2300/0654 ,  B01L2300/0663 ,  B01L2300/1811 ,  C12Q1/686 ,  C12Q2545/101 ,  G01N21/274 ,  G01N21/645 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2021/6463 ,  G01N2021/6482 ,  G01N2201/0245 ,  G01N2201/06113 ,  G01N2201/0628 ,  G01N2201/0635 ,  G01N2201/0636 ,  G01N2201/068 ,  C12Q2563/107

Abstract: An optical instrument monitors PCR replication of DNA in a reaction apparatus having a temperature cycled block with vials of reaction ingredients including dye that fluoresces in presence of double-stranded DNA. A beam splitter passes an excitation beam to the vials to fluoresce the dye. An emission beam from the dye is passed by the beam splitter to a CCD detector from which a processor computes DNA concentration. A reference strip with a plurality of reference emitters emit reference beams of different intensity, from which the processor selects an optimum emitter for compensating for drift. Exposure time is automatically adjusted for keeping within optimum dynamic ranges of the CCD and processor. A module of the beam splitter and associated optical filters is associated with selected dye, and is replaceable for different dyes.

公开(公告)号：US20040145737A1

公开(公告)日：2004-07-29

申请号：US10352828

申请日：2003-01-28

Applicant: Honeywell International Inc.

Inventor： G. Benjamin Hocker

IPC: G01J003/28

CPC classification number: G01N29/2425 ,  G01J3/28 ,  G01J3/457 ,  G01N21/1702 ,  G01N2021/1725 ,  G01N2201/0635 ,  G01N2201/0691

Abstract: A programmable substance detector includes a light source, a sample cell, a programmable diffraction grating positioned to receive light from the light source and to direct diffracted light to the sample cell, and a detector associated with the cell to detect a match between a characteristic of the diffracted light and a corresponding characteristic of a substance within the cell.

Abstract translation: 可编程物质检测器包括光源，样品池，定位成接收来自光源的光并将衍射光引导到样品池的可编程衍射光栅，以及与该电池相关联的检测器，用于检测 衍射光和细胞内物质的相应特征。