Rapid production of high titer virus
    29.
    发明授权
    Rapid production of high titer virus 有权
    快速生产高滴度病毒

    公开(公告)号:US07524626B2

    公开(公告)日:2009-04-28

    申请号:US11542093

    申请日:2006-10-03

    申请人: Alex J. Harvey

    发明人: Alex J. Harvey

    IPC分类号: C12Q1/70 C12N15/00

    摘要: The invention includes methods of producing viral particles which include introducing into avian cells a nucleotide sequence encoding a replication deficient retroviral vector and introducing into the avian cells nucleotide sequences encoding products required for replication of the replication deficient retroviral vector under the control of a promoter that is functional in the avian cell line, and harvesting the viral particles.

    摘要翻译: 本发明包括产生病毒颗粒的方法,其包括将编码复制缺陷型逆转录病毒载体的核苷酸序列引入禽类细胞,并将编码在复制缺陷型逆转录病毒载体复制的产物所需的核苷酸序列引入到启动子的控制下, 在禽类细胞系中起作用,并收获病毒颗粒。