公开(公告)号：US11353446B2

公开(公告)日：2022-06-07

申请号：US17433092

申请日：2020-11-06

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding

IPC: G01N33/487 ,  A61B5/145 ,  G01N33/53 ,  G01N33/66 ,  G01N33/49 ,  G01N33/58 ,  G01N35/08 ,  G01N1/22

Abstract: Disclosed is a method for correlating a biomarker in a non-blood bodily fluid with the same biomarker in the blood of an individual, including: measuring, in a first period in time, the biomarker in non-blood bodily fluid and measuring the same biomarker in the blood of the same individual to establish an R ratio of [NBBF1]/[BB1], where [NBBF1] is the biomarker concentration in non-blood bodily fluid in the first period in time, and [BB1] is the biomarker concentration in the blood in the first period in time; storing the ratio in a memory; measuring, in a second period in time, the biomarker in non-blood bodily fluid to determine [NBBF2], where [NBBF2] is the biomarker concentration in the non-blood bodily fluid in the second period in time; and correlating the measured [NBBF2] with the R ratio to generate a correlated [BB2] biomarker concentration in the blood of the individual in the second period in time. Also disclosed is a device, apparatus, and method for correlating the glucose concentration in a non-blood bodily fluid such as saliva with the glucose in the blood of an individual.

公开(公告)号：US20220091092A1

公开(公告)日：2022-03-24

申请号：US17433092

申请日：2020-11-06

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Wei DING

IPC: G01N33/487 ,  G01N33/66 ,  G01N33/53 ,  A61B5/145

Abstract: Disclosed is a method for correlating a biomarker in a non-blood bodily fluid with the same biomarker in the blood of an individual, including: measuring, in a first period in time, the biomarker in non-blood bodily fluid and measuring the same biomarker in the blood of the same individual to establish an R ratio of [NBBF1]/[BB1], where [NBBF1] is the biomarker concentration in non-blood bodily fluid in the first period in time, and [BB1] is the biomarker concentration in the blood in the first period in time; storing the ratio in a memory; measuring, in a second period in time, the biomarker in non-blood bodily fluid to determine [NBBF2], where [NBBF2] is the biomarker concentration in the non-blood bodily fluid in the second period in time; and correlating the measured [NBBF2] with the R ratio to generate a correlated [BB2] biomarker concentration in the blood of the individual in the second period in time. Also disclosed is a device, apparatus, and method for correlating the glucose concentration in a non-blood bodily fluid such as saliva with the glucose in the blood of an individual.

公开(公告)号：USD912842S1

公开(公告)日：2021-03-09

申请号：US29671683

申请日：2018-11-29

Applicant: Essenlix Corporation

Designer： Stephen Y. Chou ,  Wei Ding ,  Ji Qi ,  Hua Tan

公开(公告)号：US10830761B2

公开(公告)日：2020-11-10

申请号：US16533722

申请日：2019-08-06

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding

IPC: G01N33/497 ,  B01L3/00 ,  G01N1/28 ,  A61B5/083 ,  A61B5/093 ,  A61B5/097 ,  G01N21/01 ,  G01N33/58 ,  G01N1/22

Abstract: The present invention is related to the field of bio/chemical sensing, assays and applications. Particularly, the present invention is related to collecting a small amount of a vapor condensate sample (e.g. the exhaled breath condensate (EBC) from a subject of a volume as small as 10 fL (femto-Liter) in a single drop), preventing or significantly reducing an evaporation of the collected vapor condensate sample, analyzing the sample, analyzing the sample by mobile-phone, and performing such collection and analysis by a person without any professionals.

公开(公告)号：US20200330029A1

公开(公告)日：2020-10-22

申请号：US16772852

申请日：2018-12-14

Applicant: Essenlix Corporation

Inventor： Stephen CHOU ,  Wei DING

IPC: A61B5/00 ,  G01N33/53 ,  G06T7/00 ,  G16H30/20 ,  G16H50/20

Abstract: Device, systems, and methods are provided that can be used to monitor, examine, and/or analyze hair conditions and make suggestions to improve the hair conditions.

公开(公告)号：US20200284790A1

公开(公告)日：2020-09-10

申请号：US16759050

申请日：2018-10-26

Applicant: Essenlix Corporation

Inventor： Stephen CHOU ,  Wei DING ,  Ji LI ,  Sheng-Jian CAI

IPC: G01N33/543 ,  G01N33/577 ,  G01N33/50 ,  G01N33/58 ,  G01N21/64

Abstract: Methods and devices are provided for rapid detection in a sample of bacteria that cause sexually transmitted diseases (chlamydia, gonorrhea, or syphilis). Methods and devices are also provided for the rapid detection of immune cells (CD3, CD4 and CD8 cells).

公开(公告)号：US10605805B2

公开(公告)日：2020-03-31

申请号：US15742744

申请日：2016-09-14

Applicant: ESSENLIX CORPORATION

Inventor： Stephen Y. Chou ,  Wei Ding

IPC: G01N33/543 ,  G01N1/28 ,  G16H80/00 ,  B01L3/00 ,  G01N1/30 ,  G01N33/50

Abstract: The present invention is related to the field of bio/chemical sampling, sensing, assays and applications. Particularly, the present invention is related to how to make the sampling/sensing/assay become simple to use, fast to results, highly sensitive, easy to use, using tiny sample volume (e.g. 0.5 uL or less), operated by a person without any professionals, reading by mobile-phone, or low cost, or a combination of them.

公开(公告)号：US20200038859A1

公开(公告)日：2020-02-06

申请号：US16484620

申请日：2018-02-08

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding ,  Yufan Zhang

IPC: B01L3/00 ,  C12Q1/686 ,  G01N33/53

Abstract: Provided herein is a method and device for partitioning a fluidic sample. The device contains a plate containing microwells. The method comprises depositing a sample on one or both of the plates when the plates are in an open configuration, wherein the deposition is in the form of a single or multiple droplet of the sample, wherein at least one of the droplets has a volume that occupies more than two microwells and closing the plates to the closed configuration to partition the sample in the microwells.

公开(公告)号：US10324009B2

公开(公告)日：2019-06-18

申请号：US15742521

申请日：2016-08-10

Applicant: ESSENLIX CORPORATION

Inventor： Stephen Y. Chou ,  Wei Ding

IPC: G01N1/28 ,  G01N35/00 ,  G01N21/64 ,  G01N33/49 ,  G01N33/543 ,  G01N1/30 ,  G01N15/14 ,  G01N21/69 ,  G01N21/76 ,  G01N21/65 ,  G01N15/00

Abstract: The present invention is related to the field of bio/chemical sampling, sensing, assays and applications. Particularly, the present invention is related to how to make the sampling/sensing/assay become simple to use, fast to results, highly sensitive, easy to use, using tiny sample volume (e.g. 0.5 uL or less), operated by a person without any professionals, reading by mobile-phone, or low cost, or a combination of them.

公开(公告)号：US10132794B2

公开(公告)日：2018-11-20

申请号：US15561014

申请日：2016-09-14

Applicant: ESSENLIX CORPORATION

Inventor： Stephen Y. Chou ,  Wei Ding

IPC: G01N33/497 ,  A61B5/083 ,  A61B5/093 ,  A61B5/097 ,  G01N21/01 ,  G01N33/58

Abstract: The present invention is related to the field of bio/chemical sensing, assays and applications. Particularly, the present invention is related to collecting a small amount of a vapor condensate sample (e.g. the exhaled breath condensate (EBC) from a subject of a volume as small as 10 fL (femto-Liter) in a single drop), preventing or significantly reducing an evaporation of the collected vapor condensate sample, analyzing the sample, analyzing the sample by mobile-phone, and performing such collection and analysis by a person without any professionals.