公开(公告)号：US20240377389A1

公开(公告)日：2024-11-14

申请号：US18416792

申请日：2024-01-18

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Wei DING ,  Ji LI ,  Yufan Zhang

IPC: G01N33/543 ,  B01L3/00 ,  G01N21/29 ,  G01N33/50

Abstract: Among other things, the present invention is related to bio/chemical sampling, sensing, assays and applications.

公开(公告)号：US20240309369A1

公开(公告)日：2024-09-19

申请号：US18388193

申请日：2023-11-09

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Wei DING ,  Ji QI ,  Jun Tian ,  Wu Chou

IPC: C12N15/113 ,  A61K31/7088 ,  A61K45/06 ,  A61K47/54 ,  A61P31/04

CPC classification number: C12N15/113 ,  A61K31/7088 ,  A61K45/06 ,  A61K47/554 ,  A61P31/04 ,  C12N15/1137 ,  C12N2310/127 ,  C12N2310/3515 ,  C12Y305/02006

Abstract: Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between containing between two plates.

公开(公告)号：US20230408534A1

公开(公告)日：2023-12-21

申请号：US18030980

申请日：2021-10-08

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Wei DING ,  Wu CHOU ,  Xing LI ,  Mingquan WU

IPC: G01N35/00 ,  G06T7/00

CPC classification number: G01N35/00613 ,  G01N35/00029 ,  G06T2207/20081 ,  G01N2035/00148 ,  G06T2207/30024 ,  G06T7/0012

Abstract: The present invention is related to, among other things, the devices and methods that improve the accuracy and reliability of an assay, even when the assay device and/or the operation of the assay device has certain errors, and in some embodiments, the errors are random. One aspect of the present invention is to overcome the random errors or imperfections of an assay device or the operation of the assay device by measuring, in addition to measuring the analyte in a sample to generate an analyte test result, the trustworthiness of the analyte test result. The analyte test result will be reported, only when the trustworthiness meets a predetermined threshold, otherwise the analyte test result will be discarded. Various of parameter variation have been used for test trustworthy determination.

公开(公告)号：US20230061137A1

公开(公告)日：2023-03-02

申请号：US17975752

申请日：2022-10-28

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Wei DING

IPC: A61B5/00 ,  G16H30/20 ,  G16H50/20 ,  G01N33/53 ,  G06T7/00

Abstract: Device, systems, and methods are provided that can be used to monitor, examine, and/or analyze hair conditions and make suggestions to improve the hair conditions.

公开(公告)号：US20220357271A1

公开(公告)日：2022-11-10

申请号：US17621216

申请日：2020-06-22

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Wei DING ,  Ji QI ,  Jun TIAN ,  Wu CHOU ,  Hongbing LI

IPC: G01N21/31 ,  G01N21/03

Abstract: The disclosure provides an apparatus, a device, and methods for improving optical analysis of a thin layer of a sample between two plates, particularly for multiple wavelengths.

公开(公告)号：US20220276235A1

公开(公告)日：2022-09-01

申请号：US17627877

申请日：2020-09-18

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Wei DING ,  Ji LI

IPC: G01N33/543 ,  G06V20/69 ,  G06V10/70 ,  G06V10/60

Abstract: Among other things, the present disclosure provides devices and methods for improving a homogeneous assay, particularly in improving accuracy, reduce noises, none-perfect conditions, multiplexing, etc.

公开(公告)号：US20220091092A1

公开(公告)日：2022-03-24

申请号：US17433092

申请日：2020-11-06

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Wei DING

IPC: G01N33/487 ,  G01N33/66 ,  G01N33/53 ,  A61B5/145

Abstract: Disclosed is a method for correlating a biomarker in a non-blood bodily fluid with the same biomarker in the blood of an individual, including: measuring, in a first period in time, the biomarker in non-blood bodily fluid and measuring the same biomarker in the blood of the same individual to establish an R ratio of [NBBF1]/[BB1], where [NBBF1] is the biomarker concentration in non-blood bodily fluid in the first period in time, and [BB1] is the biomarker concentration in the blood in the first period in time; storing the ratio in a memory; measuring, in a second period in time, the biomarker in non-blood bodily fluid to determine [NBBF2], where [NBBF2] is the biomarker concentration in the non-blood bodily fluid in the second period in time; and correlating the measured [NBBF2] with the R ratio to generate a correlated [BB2] biomarker concentration in the blood of the individual in the second period in time. Also disclosed is a device, apparatus, and method for correlating the glucose concentration in a non-blood bodily fluid such as saliva with the glucose in the blood of an individual.

公开(公告)号：US20250116593A1

公开(公告)日：2025-04-10

申请号：US18739128

申请日：2024-06-10

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Wu CHOU ,  Xing LI ,  Hongbing LI ,  Yuecheng Zhang ,  Mingquan WU ,  Wei DING ,  Jun TIAN

IPC: G01N15/1433 ,  G06N20/00 ,  G06T7/00 ,  G06T7/10 ,  G06T7/40 ,  G06T7/62

Abstract: The present invention is related to, among other things, the devices and methods that improve the accuracy and reliability of an assay, even when the assay device and/or the operation of the assay device has certain errors, and in some embodiments the errors are random.

公开(公告)号：US20240125705A1

公开(公告)日：2024-04-18

申请号：US18389758

申请日：2023-12-19

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Wei DING ,  Ji LI ,  Shengjian Cai ,  Yufan Zhang ,  Jia Peng

IPC: G01N21/64 ,  G01N1/30 ,  G01N21/76 ,  G01N33/543

CPC classification number: G01N21/6458 ,  G01N1/30 ,  G01N21/76 ,  G01N33/54373

Abstract: The present invention provides, among other things, devices, kits, apparatus, and methods for rapid homogenous cell staining and imaging. Particularly, in some embodiments, the present invention can immunochemically stain a cell or a tissue in less than 60 seconds without washing. In some embodiments, the present invention stains and observes analyte (protein or nucleic acid) inside a cell in 60 seconds without washing.

公开(公告)号：US20230400469A1

公开(公告)日：2023-12-14

申请号：US17787804

申请日：2020-12-21

Applicant: Essenlix Corporation

Inventor： Stephen Y. CHOU ,  Susan Y. SUN ,  Shengjian CAI ,  Wei DING

IPC: G01N33/58 ,  G01N21/64 ,  G01N1/30

CPC classification number: G01N33/582 ,  G01N21/6428 ,  G01N2800/26 ,  G01N2001/302 ,  G01N2021/6439 ,  G01N1/30

Abstract: The present invention is to provide methods and devices that monitoring health and diagnosing a disease by directly measuring the biomarkers inside a cell (intra-cellular detection) rapidly and easily.