公开(公告)号：US20090118728A1

公开(公告)日：2009-05-07

申请号：US11941894

申请日：2007-11-16

Applicant: Isaac Ostrovsky ,  Jon T. McIntyre

Inventor： Isaac Ostrovsky ,  Jon T. McIntyre

IPC: A61B18/18 ,  A61F2/00

CPC classification number: A61B18/1482 ,  A61B18/14 ,  A61B18/1442 ,  A61B18/1815 ,  A61B2018/00273 ,  A61B2018/00702 ,  A61B2018/00875 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61B2018/1475

Abstract: A tissue ablation device comprises first and second electrodes of opposite polarities, the first electrode being mounted to a first elongated member for movement relative to the second electrode for separation therefrom by a desired distance. A method of ablating a tissue comprises inserting first and second electrodes to desired initial positions relative to a tissue mass to be ablated and applying electrical energy to the first and second electrodes to ablate a first portion of tissue between the first and second electrodes in combination with the step of applying electrical energy to desired second positions separated from the desired initial positions by a distance selected to transfer electrical energy around the first portion of tissue through a second portion of tissue to be ablated, the second portion of tissue surrounding the first portion of tissue.

Abstract translation: 组织消融装置包括具有相反极性的第一和第二电极，第一电极被安装到第一细长构件，以相对于第二电极移动，以便将其与之隔离一段期望的距离。 消融组织的方法包括将第一和第二电极相对于要消融的组织块插入所需的初始位置，并将电能施加到第一和第二电极，以将第一和第二电极之间的组织的第一部分与 将电能施加到从期望的初始位置分离所需的第二位置的距离，所述距离被选择为通过待消融的组织的第二部分转移组织周围的电能，围绕第一部分的组织的第二部分 组织。

公开(公告)号：US07426037B2

公开(公告)日：2008-09-16

申请号：US11531211

申请日：2006-09-12

Applicant: Isaac Ostrovsky ,  Mark D. Modell ,  Robert J. Crowley

Inventor： Isaac Ostrovsky ,  Mark D. Modell ,  Robert J. Crowley

IPC: G01B11/02 ,  G01B9/02

CPC classification number: G01B9/02007 ,  G01B9/02002 ,  G01B9/02029 ,  G01B9/02032 ,  G01B9/02044 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70 ,  G01N21/4795

Abstract: Diffraction grating based fiber optic interferometric systems for use in optical coherence tomography, wherein sample and reference light beams are formed by a first beam splitter and the sample light beam received from a sample and a reference light beam are combined on a second beam splitter. In one embodiment, the first beam splitter is an approximately 50/50 beam splitter, and the second beam splitter is a non 50/50 beam splitter. More than half of the energy of the sample light beam is directed into the combined beam and less than half of the energy of the reference light beam are directed into the combined beam by the second beam splitter. In another embodiment, the first beam splitter is a non 50/50 beam splitter and the second beam splitter is an approximately 50/50 beam splitter. An optical circulator is provided to enable the sample light beam to bypass the first beam splitter after interaction with a sample. Two combined beams are formed by the second beam splitter for detection by two respective detectors. More than half of the energy of the light source provided to the first beam splitter is directed into the sample light beam and less than half of the energy is directed into the reference light beam. The energy distribution between the sample and reference light beams can be controlled by selection of the characteristics of the beam splitters.

Abstract translation: 用于光学相干断层摄影的基于衍射光栅的光纤干涉系统，其中采样和参考光束由第一分束器形成，并且从样本和参考光束接收的样本光束被组合在第二分束器上。 在一个实施例中，第一分束器是大约50/50分束器，并且第二分束器是非50/50分束器。 样品光束的一半以上的能量被引导到组合光束中，并且参考光束的能量的不到一半被第二分束器引导到组合光束中。 在另一个实施例中，第一分束器是非50/50分束器，第二分束器是大约50/50分束器。 提供光环行器以使得样品光束能够在与样品相互作用之后绕过第一分束器。 两个组合光束由第二分束器形成，用于由两个相应的检测器检测。 提供给第一分束器的光源的能量的一半以上被引导到样本光束中，并且少于一半的能量被引导到参考光束中。 可以通过选择分束器的特性来控制样品和参考光束之间的能量分布。

公开(公告)号：US07314448B2

公开(公告)日：2008-01-01

申请号：US10754292

申请日：2004-01-09

Applicant: Louis J. Barbato ,  Isaac Ostrovsky ,  Paul Goll ,  Thomas C. Moore ,  Douglas M. Petty ,  Mark Hamm ,  Richard Romley

Inventor： Louis J. Barbato ,  Isaac Ostrovsky ,  Paul Goll ,  Thomas C. Moore ,  Douglas M. Petty ,  Mark Hamm ,  Richard Romley

IPC: A61B8/12

CPC classification number: A61B8/4461 ,  A61B5/06 ,  A61B5/062 ,  A61B8/12 ,  A61B8/4254

Abstract: An improved medical imaging device assembly includes an imaging transducer coupled to the distal end of a drive shaft, and a conductive wire is wrapped around a distal portion of the drive shaft, wherein the conductive wire reinforces the imaging device assembly. In one embodiment, the conductive wire is part of a sensor adapted to communicate with a medical positioning system. In another embodiment, the conductive wire is configured to be a matching circuit for the imaging transducer. The conductive wire may be configured to be in parallel with the imaging transducer or configured to be in series with the imaging transducer.

Abstract translation: 一种改进的医学成像装置组件包括联接到驱动轴的远端的成像传感器，并且导电线围绕驱动轴的远端部分缠绕，其中导线加强成像装置组件。 在一个实施例中，导线是适于与医疗定位系统通信的传感器的一部分。 在另一实施例中，导线被配置为成像换能器的匹配电路。 导线可以被配置为与成像换能器并联或被配置成与成像换能器串联。

公开(公告)号：US07306595B2

公开(公告)日：2007-12-11

申请号：US10993306

申请日：2004-11-18

Applicant: Isaac Ostrovsky ,  Jon T. McIntyre

Inventor： Isaac Ostrovsky ,  Jon T. McIntyre

IPC: A61B18/18

CPC classification number: A61B18/1482 ,  A61B18/14 ,  A61B18/1442 ,  A61B18/1815 ,  A61B2018/00273 ,  A61B2018/00702 ,  A61B2018/00875 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61B2018/1475

Abstract: A tissue ablation device comprises first and second electrodes of opposite polarities, the first electrode being mounted to a first elongated member for movement relative to the second electrode for separation therefrom by a desired distance. A method of ablating a tissue comprises inserting first and second electrodes to desired initial positions relative to a tissue mass to be ablated and applying electrical energy to the first and second electrodes to ablate a first portion of tissue between the first and second electrodes in combination with the step of applying electrical energy to desired second positions separated from the desired initial positions by a distance selected to transfer electrical energy around the first portion of tissue through a second portion of tissue to be ablated, the second portion of tissue surrounding the first portion of tissue.

Abstract translation: 组织消融装置包括具有相反极性的第一和第二电极，第一电极被安装到第一细长构件，以相对于第二电极移动，以便将其与之隔离一段期望的距离。 消融组织的方法包括将第一和第二电极相对于要消融的组织块插入所需的初始位置，并将电能施加到第一和第二电极，以将第一和第二电极之间的组织的第一部分与 将电能施加到从期望的初始位置分离所需的第二位置的距离，所述距离被选择为通过待消融的组织的第二部分转移围绕组织的第一部分的电能，围绕第一部分的组织的第二部分 组织。

公开(公告)号：US20060106314A1

公开(公告)日：2006-05-18

申请号：US11289981

申请日：2005-11-29

Applicant: Isaac Ostrovsky

Inventor： Isaac Ostrovsky

IPC: A61B8/14

CPC classification number: A61B8/12 ,  A61B5/062 ,  A61B8/4254 ,  A61B8/4461

Abstract: The present invention is generally directed towards an imaging transducer assembly. Generally, the imaging transducer assembly is combined with a sensor of a medical positioning system. In one aspect, the transducer assembly and the sensor share the same voltage source. In another aspect of the invention, the sensor surrounds a portion of the imaging transducer assembly, forming a housing that reinforces the assembly.

公开(公告)号：US07006231B2

公开(公告)日：2006-02-28

申请号：US10017534

申请日：2001-10-18

Applicant: Isaac Ostrovsky ,  Mark D. Modell ,  Robert J. Crowley

Inventor： Isaac Ostrovsky ,  Mark D. Modell ,  Robert J. Crowley

IPC: G01B9/02

CPC classification number: G01B9/02007 ,  G01B9/02002 ,  G01B9/02029 ,  G01B9/02032 ,  G01B9/02044 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70 ,  G01N21/4795

Abstract: Diffraction grating based fiber optic interferometric systems for use in optical coherence tomography, wherein sample and reference light beams are formed by a first beam splitter and the sample light beam received from a sample and a reference light beam are combined on a second beam splitter. In one embodiment, the first beam splitter is an approximately 50/50 beam splitter, and the second beam splitter is a non 50/50 beam splitter. More than half of the energy of the sample light beam is directed into the combined beam and less than half of the energy of the reference light beam are directed into the combined beam by the second beam splitter. In another embodiment, the first beam splitter is a non 50/50 beam splitter and the second beam splitter is an approximately 50/50 beam splitter. An optical circulator is provided to enable the sample light beam to bypass the first beam splitter after interaction with a sample. Two combined beams are formed by the second beam splitter for detection by two respective detectors. More than half of the energy of the light source provided to the first beam splitter is directed into the sample light beam and less than half of the energy is directed into the reference light beam. The energy distribution between the sample and reference light beams can be controlled by selection of the characteristics of the beam splitters.

公开(公告)号：US06996432B2

公开(公告)日：2006-02-07

申请号：US10639299

申请日：2003-08-11

Applicant: Isaac Ostrovsky ,  William E. Webler ,  Mark S. Buhr

Inventor： Isaac Ostrovsky ,  William E. Webler ,  Mark S. Buhr

IPC: A61B5/05 ,  A61B8/12

CPC classification number: A61B8/12 ,  A61B5/06 ,  A61B5/062 ,  A61B8/4209 ,  A61B8/4245 ,  A61B8/4461 ,  G01S7/52079 ,  G01S15/8936

Abstract: An improved medical imaging system preferably includes an imaging device having a housing, an imaging transducer, and a position marker coupled near the imaging transducer. The system further includes a motor capable of driving the imaging transducer in a generally longitudinal direction relative to the housing. Data obtained from tracking the position marker may be cross-correlated with data obtained from the imaging transducer. In one aspect, the position marker may be a sensor capable of communicating with a medical positioning system.

Abstract translation: 改进的医学成像系统优选地包括具有壳体，成像换能器和耦合在成像换能器附近的位置标记的成像装置。 该系统还包括能够相对于壳体沿大致纵向方向驱动成像换能器的电动机。 从跟踪位置标记获得的数据可以与从成像换能器获得的数据互相关。 在一个方面，位置标记可以是能够与医疗定位系统通信的传感器。

公开(公告)号：US20050264826A1

公开(公告)日：2005-12-01

申请号：US11166522

申请日：2005-06-24

Applicant: Isaac Ostrovsky ,  Mark Modell ,  Robert Crowley

Inventor： Isaac Ostrovsky ,  Mark Modell ,  Robert Crowley

IPC: G01B9/02 ,  G01B11/02

CPC classification number: G01B9/02007 ,  G01B9/02002 ,  G01B9/02029 ,  G01B9/02032 ,  G01B9/02044 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70 ,  G01N21/4795

Abstract: Diffraction grating based fiber optic interferometric systems for use in optical coherence tomography, wherein sample and reference light beams are formed by a first beam splitter and the sample light beam received from a sample and a reference light beam are combined on a second beam splitter. In one embodiment, the first beam splitter is an approximately 50/50 beam splitter, and the second beam splitter is a non 50/50 beam splitter. More than half of the energy of the sample light beam is directed into the combined beam and less than half of the energy of the reference light beam are directed into the combined beam by the second beam splitter. In another embodiment, the first beam splitter is a non 50/50 beam splitter and the second beam splitter is an approximately 50/50 beam splitter. An optical circulator is provided to enable the sample light beam to bypass the first beam splitter after interaction with a sample. Two combined beams are formed by the second beam splitter for detection by two respective detectors. More than half of the energy of the light source provided to the first beam splitter is directed into the sample light beam and less than half of the energy is directed into the reference light beam. The energy distribution between the sample and reference light beams can be controlled by selection of the characteristics of the beam splitters.

Abstract translation: 用于光学相干断层摄影的基于衍射光栅的光纤干涉系统，其中采样和参考光束由第一分束器形成，并且从样本和参考光束接收的样本光束被组合在第二分束器上。 在一个实施例中，第一分束器是大约50/50分束器，并且第二分束器是非50/50分束器。 样品光束的一半以上的能量被引导到组合光束中，并且参考光束的能量的不到一半被第二分束器引导到组合光束中。 在另一个实施例中，第一分束器是非50/50分束器，第二分束器是大约50/50分束器。 提供光环行器以使得样品光束能够在与样品相互作用之后绕过第一分束器。 两个组合光束由第二分束器形成，用于由两个相应的检测器检测。 提供给第一分束器的光源的能量的一半以上被引导到样本光束中，并且少于一半的能量被引导到参考光束中。 可以通过选择分束器的特性来控制样品和参考光束之间的能量分布。

公开(公告)号：US20050107781A1

公开(公告)日：2005-05-19

申请号：US10993306

申请日：2004-11-18

Applicant: Isaac Ostrovsky ,  Jon McIntyre

Inventor： Isaac Ostrovsky ,  Jon McIntyre

IPC: A61B18/14

CPC classification number: A61B18/1482 ,  A61B18/14 ,  A61B18/1442 ,  A61B18/1815 ,  A61B2018/00273 ,  A61B2018/00702 ,  A61B2018/00875 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61B2018/1475

Abstract: A tissue ablation device comprises first and second electrodes of opposite polarities, the first electrode being mounted to a first elongated member for movement relative to the second electrode for separation therefrom by a desired distance. A method of ablating a tissue comprises inserting first and second electrodes to desired initial positions relative to a tissue mass to be ablated and applying electrical energy to the first and second electrodes to ablate a first portion of tissue between the first and second electrodes in combination with the step of applying electrical energy to desired second positions separated from the desired initial positions by a distance selected to transfer electrical energy around the first portion of tissue through a second portion of tissue to be ablated, the second portion of tissue surrounding the first portion of tissue.

Abstract translation: 组织消融装置包括具有相反极性的第一和第二电极，第一电极被安装到第一细长构件，以相对于第二电极移动，以便将其与之隔离一段期望的距离。 消融组织的方法包括将第一和第二电极相对于要消融的组织块插入所需的初始位置，并将电能施加到第一和第二电极，以将第一和第二电极之间的组织的第一部分与 将电能施加到从期望的初始位置分离所需的第二位置的距离，所述距离被选择为通过待消融的组织的第二部分转移围绕组织的第一部分的电能，围绕第一部分的组织的第二部分 组织。

公开(公告)号：US06847454B2

公开(公告)日：2005-01-25

申请号：US10020040

申请日：2001-10-18

Applicant: Robert J. Crowley ,  Louis J. Barbato ,  Isaac Ostrovsky ,  Mark D. Modell

Inventor： Robert J. Crowley ,  Louis J. Barbato ,  Isaac Ostrovsky ,  Mark D. Modell

IPC: G01N21/17 ,  A61B5/00 ,  A61B8/00 ,  A61B8/12 ,  G01B9/02 ,  G01N29/06 ,  G01N29/22

CPC classification number: A61B5/6852 ,  A61B5/0066 ,  A61B5/0095 ,  A61B5/02007 ,  A61B8/12 ,  G01B9/02002 ,  G01B9/02007 ,  G01B9/02028 ,  G01B9/0203 ,  G01B9/02087 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70 ,  G01N29/06 ,  G01N29/223 ,  G01N2291/02416 ,  G01N2291/02466

Abstract: An imaging system comprises an interferometer and an ultrasound console that processes signals from the interferometer into an image for display. The interferometer may include one or more multi-element photo detectors with a plurality of parallel outputs. A parallel to serial converter is provided between the parallel output of the interferometer and the input of the ultrasound console, to convert the signals provided on the parallel outputs into a serial signal for analysis by the ultrasound console. The interferometer may be selectively coupled to the ultrasound console and the system may further comprise an ultrasound device that may also be selectively coupled to the console, offering a user the option of using either the interferometer or the ultrasound device. The ultrasound console may also include two inputs, one for the interferometer and the other for the ultrasound device. The interferometer and the ultrasound device may both be carried by catheters for insertion into internal body cavities, such as blood vessels. Imaging methods are also disclosed.

Abstract translation: 成像系统包括干涉仪和超声控制台，其将来自干涉仪的信号处理成用于显示的图像。 干涉仪可以包括具有多个并行输出的一个或多个多元素光电检测器。 在干涉仪的并行输出和超声控制台的输入之间提供并行到串行转换器，以将并行输出上提供的信号转换为串行信号，以便由超声控制台进行分析。 所述干涉仪可选择性地耦合到所述超声控制台，并且所述系统还可包括超声装置，所述超声装置还可以选择性地耦合到所述控制台，为使用者提供使用所述干涉仪或所述超声装置的选项。 超声控制台还可以包括两个输入，一个用于干涉仪，另一个用于超声装置。 干涉仪和超声波装置都可以由导管承载以插入诸如血管的内部体腔中。 还公开了成像方法。